DE68905633D1 - Markierer der t-zelle aktivierung. - Google Patents

Markierer der t-zelle aktivierung.

Info

Publication number
DE68905633D1
DE68905633D1 DE8989301341T DE68905633T DE68905633D1 DE 68905633 D1 DE68905633 D1 DE 68905633D1 DE 8989301341 T DE8989301341 T DE 8989301341T DE 68905633 T DE68905633 T DE 68905633T DE 68905633 D1 DE68905633 D1 DE 68905633D1
Authority
DE
Germany
Prior art keywords
cells
activated
cell activation
activation marker
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989301341T
Other languages
English (en)
Other versions
DE68905633T2 (de
Inventor
Keith D Brown
Timothy R Mosmann
Gerald Zurawski
Sandra M Zurawski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Biotech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Biotech Corp filed Critical Schering Biotech Corp
Publication of DE68905633D1 publication Critical patent/DE68905633D1/de
Application granted granted Critical
Publication of DE68905633T2 publication Critical patent/DE68905633T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DE8989301341T 1988-02-18 1989-02-13 Markierer der t-zelle aktivierung. Expired - Fee Related DE68905633T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/157,743 US5001230A (en) 1988-02-18 1988-02-18 T cell activation markers

Publications (2)

Publication Number Publication Date
DE68905633D1 true DE68905633D1 (de) 1993-05-06
DE68905633T2 DE68905633T2 (de) 1993-07-08

Family

ID=22565071

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989301341T Expired - Fee Related DE68905633T2 (de) 1988-02-18 1989-02-13 Markierer der t-zelle aktivierung.

Country Status (9)

Country Link
US (1) US5001230A (de)
EP (2) EP0329363B1 (de)
JP (1) JP2910861B2 (de)
AT (1) ATE87655T1 (de)
AU (1) AU3192889A (de)
CA (1) CA1340869C (de)
DE (1) DE68905633T2 (de)
ES (1) ES2046462T3 (de)
WO (1) WO1989007646A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705612A (en) 1984-10-18 1998-01-06 Institut Pasteur And Centre National De La Recherche Scientifique NEF peptide encoded by human immunodefiency virus type 1 (HIV-1)
AU582288B2 (en) * 1986-03-07 1989-03-16 Damon Biotech Inc. Vector and method for achieving high level expression in eukaryotic cells
US5637488A (en) * 1987-06-01 1997-06-10 The United States Of America As Represented By The Department Of Health And Human Services HIV protease gene and method for its expression
JP2716503B2 (ja) * 1987-12-23 1998-02-18 ジ・アップジョン・カンパニー ヒト呼吸系シンシチウムウイルスの糖蛋白類の免疫原性セグメントを含有するキメラ糖蛋白類
EP0437516A4 (en) * 1988-10-06 1991-09-25 Dana Farber Cancer Institute H. saimiri-htlv-x region vector
IL92685A0 (en) * 1988-12-16 1990-09-17 Us Commerce Dna encoding lymphokine/cytokine like proteins,cells transformed thereby and production of said proteins and antibodies against them
JP2903414B2 (ja) * 1989-05-31 1999-06-07 味の素株式会社 抗酸菌分泌発現ベクター及び抗酸菌
US6004776A (en) * 1989-07-07 1999-12-21 Unilever Patent Holdings, B.V. Process for preparing a protein by a fungus transformed by multicopy integration of an expression vector
EP0481008B1 (de) * 1989-07-07 1997-11-12 Unilever Plc Verfahren zur herstellung eines proteins mittels eines durch mehrfachkopieintegrierung eines expressionsvektors transformierten pilzes
EP0484440A4 (en) * 1989-07-28 1993-01-07 Us Health Efficient directional genetic cloning system
US5541083A (en) * 1989-10-24 1996-07-30 The Regents Of The University Of California Method for producing secretable glycosyltransferases and other golgi processing enzymes
US5976877A (en) * 1990-01-08 1999-11-02 Institut National De La Sante Et De La Recherche Medicale (Inserm) Proteins produced by human lymphocytes DNA sequence encoding these proteins and their pharmaceutical and biological uses
FR2656800B1 (fr) * 1990-01-08 1992-05-15 Roussy Inst Gustave Nouvelles proteines produits par les lymphocytes humains, sequence d'adn codant pour ces proteines et applications pharmaceutiques et biologiques.
FR2656866B1 (fr) * 1990-01-10 1992-05-15 Cis Bio Int Derives de porphyrine et metalloporphyrines eventuellement couples a une molecule biologiquement active, et composition pharmaceutique les contenant.
US5652118A (en) * 1991-03-11 1997-07-29 Creative Biomolecules, Inc. Nucleic acid encoding a novel morphogenic protein, OP-3
US5403581A (en) * 1991-07-12 1995-04-04 Hoffmann-La Roche Inc. Coccidiosis vaccines
US6008342A (en) * 1991-07-12 1999-12-28 Roche Vitamins Inc. DNA encoding eimeria antigen
US5413927A (en) * 1991-09-03 1995-05-09 North Carolina State University Feline immunodeficiency virus isolate NCSU1Lb
EP0620852A1 (de) * 1991-11-29 1994-10-26 Monsanto Company Zyklisches Di-Guanylat metabolisierende Enzyme.
TW318189B (de) * 1991-12-06 1997-10-21 American Cyanamid Co
US5721349A (en) * 1992-02-26 1998-02-24 Vanderbilt University Vacuolating toxin-deficient H. pylori
US5792751A (en) * 1992-04-13 1998-08-11 Baylor College Of Medicine Tranformation of cells associated with fluid spaces
IL108707A (en) * 1993-02-19 1999-06-20 Weiner David B Pharmaceutical compositions and diagnostic kits containing RPH protein or RPV-binding proteins
US5597707A (en) * 1993-04-15 1997-01-28 Bristol-Myers Squibb Company Tumor associated antigen recognized by the murine monoclonal antibody L6, its oligonucleotide sequence and methods for their use
WO1995016705A1 (en) * 1993-12-15 1995-06-22 The Trustees Of The University Of Pennsylvania Vpr receptor protein
US5653686A (en) * 1995-01-13 1997-08-05 Coulter Corporation Closed vial transfer method and system
US6087486A (en) * 1996-01-29 2000-07-11 The Trustees Of The University Of Pennsylvania Nucleotide sequences encoding vpr receptor protein
US6060587A (en) 1996-01-29 2000-05-09 The Trustees Of The University Of Pennsylvania Cellular receptor for HIV-1 VPR essential for G2/M phase transition of the cell cycle
EP0990001B1 (de) * 1997-05-29 2006-05-10 Agresearch Limited Verfahren zur herstellung von immunoglobulin a in milch
US6121021A (en) * 1997-12-16 2000-09-19 Connaught Laboratories Limited Constitutive expression of non-infectious HIV-like particles
US6087128A (en) 1998-02-12 2000-07-11 Ndsu Research Foundation DNA encoding an avian E. coli iss
US6448078B1 (en) 1998-10-09 2002-09-10 The Trustees Of The University Of Pennsylvania Cellular receptor for HIV-1 Vpr essential for G2/M phase transition of the cell cycle
CA2376245A1 (en) * 1999-07-29 2001-02-08 Dyax Corp. Binding moieties for fibrin
TWI240632B (en) 2001-07-30 2005-10-01 Epix Medical Inc Purified peptides for peptide-based multimeric targeted contrast agents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4358535A (en) * 1980-12-08 1982-11-09 Board Of Regents Of The University Of Washington Specific DNA probes in diagnostic microbiology
US4483920A (en) * 1982-05-17 1984-11-20 Hahnemann University Immobilization of message RNA directly from cells onto filter material
EP0194626A3 (de) * 1985-03-15 1988-05-18 Sloan-Kettering Institute For Cancer Research Verfahren zur Transformation und direkten Selektion von Transformanten in eukaryotischen Zellen
US4788137A (en) * 1985-10-29 1988-11-29 Dana-Farber Cancer Institute, Inc. Detection of activated T-cells
ATE116329T1 (de) * 1985-12-03 1995-01-15 T Cell Sciences Inc Zellenfreier t-zellenantigenrezeptor und klinische verwendung.
DE260880T1 (de) * 1986-09-11 1988-11-03 Dana-Farber Cancer Institute, Inc., Boston, Mass., Us Verfahren zur ausloesung der zytotoxizitaet.

Also Published As

Publication number Publication date
EP0415930A1 (de) 1991-03-13
ATE87655T1 (de) 1993-04-15
EP0329363A1 (de) 1989-08-23
JP2910861B2 (ja) 1999-06-23
ES2046462T3 (es) 1994-02-01
EP0329363B1 (de) 1993-03-31
JPH03504316A (ja) 1991-09-26
US5001230A (en) 1991-03-19
AU3192889A (en) 1989-09-06
DE68905633T2 (de) 1993-07-08
CA1340869C (en) 2000-01-04
WO1989007646A1 (en) 1989-08-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SCHERING CORP., KENILWORTH, N.J., US

8339 Ceased/non-payment of the annual fee