DE627218T1 - Schnelllösliche tablette. - Google Patents

Schnelllösliche tablette.

Info

Publication number
DE627218T1
DE627218T1 DE0627218T DE93904312T DE627218T1 DE 627218 T1 DE627218 T1 DE 627218T1 DE 0627218 T DE0627218 T DE 0627218T DE 93904312 T DE93904312 T DE 93904312T DE 627218 T1 DE627218 T1 DE 627218T1
Authority
DE
Germany
Prior art keywords
rapidly
tablet
water
soluble
sugar alcohol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE0627218T
Other languages
English (en)
Inventor
Shogo Izumi
Kouichi Nakamichi
Hiroyuki Yasuura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=13406427&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE627218(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of DE627218T1 publication Critical patent/DE627218T1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Claims (6)

PATENTANSPRÜCHE
1. Schnellösliche Tablette mit zwei Merkmalen: (1) der Grundbestandteil der Tablette ist ein in Wasser schnell ösl icher pharmazeutischer Zusatzstoff, und (2) eine Knetmischung aus einem Medikament und einem in Wasser schnellösliehen pharmazeutischen Zusatzstoff wird vor dem Trocknen formgepreßt, wenn in dem Verfahren zur Herstellung medi kamentenhal tiger Tabletten durch Naßgranulation ein Formpressen erfolgt.
2. Schnellösliche Tablette nach Anspruch 1, wobei der in Wasser schnellösliche pharmazeutische Zusatzstoff ein Zuckeralkohol oder Zucker ist.
3. Schnellösliche Tablette nach Anspruch 2, wobei der Zuckeralkohol Xylit ist.
4. Schnellösliche Tablette nach Anspruch 3, wobei die Tablette bei einer Formpreßdruckkraft von 50 - 300 kgf hergestellt wird.
5. Schnellösliche Tablette nach Anspruch 1, wobei der in Wasser schnellösliehe Zusatzstoff eine Mischung aus Xylit und Lactose ist.
6. Schnellösliehe Tablette nach Anspruch 1, wobei der in Wasser schnellösliche Zusatzstoff eine Mischung aus Xylit und Mannit ist.
DE0627218T 1992-02-18 1993-02-17 Schnelllösliche tablette. Pending DE627218T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6956592 1992-02-18
PCT/JP1993/000192 WO1993015724A1 (en) 1992-02-18 1993-02-17 Fast soluble tablet

Publications (1)

Publication Number Publication Date
DE627218T1 true DE627218T1 (de) 1995-08-24

Family

ID=13406427

Family Applications (2)

Application Number Title Priority Date Filing Date
DE0627218T Pending DE627218T1 (de) 1992-02-18 1993-02-17 Schnelllösliche tablette.
DE69331378T Expired - Lifetime DE69331378D1 (de) 1992-02-18 1993-02-17 Verfahren zur Herstellung von schnelllöslicher Tabletten und schnelllöslichen Tablette beinhaltend Xylitol

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69331378T Expired - Lifetime DE69331378D1 (de) 1992-02-18 1993-02-17 Verfahren zur Herstellung von schnelllöslicher Tabletten und schnelllöslichen Tablette beinhaltend Xylitol

Country Status (7)

Country Link
US (1) US5837285A (de)
EP (1) EP0627218B1 (de)
KR (1) KR100286505B1 (de)
AT (1) ATE210968T1 (de)
CA (1) CA2130487A1 (de)
DE (2) DE627218T1 (de)
WO (1) WO1993015724A1 (de)

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US20040062799A1 (en) * 1997-09-29 2004-04-01 Ayer Atul D. Therapeutic composition and delivery system for administering drug
US20030095927A1 (en) * 1997-10-01 2003-05-22 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating muscular and skeletal disorders
CN100379407C (zh) * 1997-12-19 2008-04-09 史密丝克莱恩比彻姆公司 生产咀嚼分散片的方法
US6413541B1 (en) 1999-01-13 2002-07-02 Dainippon Pharmaceutical Co., Ltd. Disintegrating tablet in oral cavity and production thereof
US6465009B1 (en) * 1998-03-18 2002-10-15 Yamanouchi Pharmaceutical Co., Ltd. Water soluble polymer-based rapidly dissolving tablets and production processes thereof
ATE308343T1 (de) 1998-07-15 2005-11-15 Asahi Kasei Chemicals Corp Trägerhilfstoff
US6368625B1 (en) * 1998-08-12 2002-04-09 Cima Labs Inc. Orally disintegrable tablet forming a viscous slurry
FR2786665B1 (fr) * 1998-12-08 2001-02-23 Maurel Sante Compositions de type fondant a base de polyols, compositions pharmaceutiques et complements alimentaires incluant de telles compositions et leurs procedes de preparation
FR2787110B1 (fr) * 1998-12-11 2001-02-16 Roquette Freres Sorbitol pulverulent et son procede de preparation
US6552024B1 (en) 1999-01-21 2003-04-22 Lavipharm Laboratories Inc. Compositions and methods for mucosal delivery
US6680071B1 (en) 1999-03-03 2004-01-20 R. P. Scherer Technologies, Inc. Opioid agonist in a fast dispersing dosage form
DE19931708A1 (de) 1999-07-08 2001-01-18 Bayer Ag Verfahren zur Herstellung schnell zerfallender, fester pharmazeutischer Zubereitungen
US6375982B1 (en) 2000-07-05 2002-04-23 Capricorn Pharma, Inc. Rapid-melt semi-solid compositions, methods of making same and method of using same
AU2001279284A1 (en) * 2000-07-05 2002-01-14 Capricorn Pharma, Inc Rapid-melt semi-solid compositions, methods of making same and methods of using same
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US7799342B2 (en) 2000-12-06 2010-09-21 Wyeth Llc Fast dissolving tablet
US6733781B2 (en) * 2000-12-06 2004-05-11 Wyeth Fast dissolving tablet
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WO2002062315A1 (en) * 2001-02-08 2002-08-15 Pharmacia Corporation Rapid-onset medicament for the treatment of sexual dysfunction
CA2440361A1 (en) * 2001-03-06 2002-09-12 Kyowa Hakko Kogyo Co. Ltd. Intraorally rapidly disintegrable preparation
US6872405B2 (en) * 2001-05-10 2005-03-29 Yamanouchi Pharmaceutical Co., Ltd. Quick-disintegrating tablet in buccal cavity and manufacturing method thereof
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US6455557B1 (en) * 2001-11-28 2002-09-24 Elan Pharmaceuticals, Inc. Method of reducing somnolence in patients treated with tizanidine
US20040220240A1 (en) * 2001-11-28 2004-11-04 Pellegrini Cara A. Method of increasing the extent of absorption of tizanidine
US20040010035A1 (en) * 2002-07-15 2004-01-15 Ciociola Arthur A. Gastrointestinal compositions
US6986901B2 (en) * 2002-07-15 2006-01-17 Warner-Lambert Company Llc Gastrointestinal compositions
BR0312501A (pt) * 2002-07-10 2005-04-12 Warner Lambert Co Combinação de um inibidor alostérico ou metaloproteinase de matriz-13 com um inibidor de ciclooxigenase-2 diferente de celecoxib ou valdecoxib
WO2004014337A2 (en) * 2002-08-02 2004-02-19 Ranbaxy Laboratories Limited A process for the preparation of dispersible tablet of cephalexin
AU2003277296A1 (en) * 2002-10-04 2004-05-04 Pharmacia Corporation Compositions and methods for treating sexual dysfunction
WO2004043431A1 (en) 2002-11-12 2004-05-27 Teva Pharmaceutical Industries Ltd. Pharmaceutical compositions and dosage forms for buccal and sublingual delivery of tizanidine and methods of administering tizanidine sublingually or bucally
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
US7282217B1 (en) 2003-08-29 2007-10-16 Kv Pharmaceutical Company Rapidly disintegrable tablets
JP4771956B2 (ja) 2003-11-04 2011-09-14 スパーナス ファーマシューティカルズ インコーポレイテッド バイオアベイラビリティーエンハンサを含む第四級アンモニウム化合物の組成物
DK2210605T3 (en) * 2003-11-04 2017-05-22 Tcd Royalty Sub Llc Daily single dose doses of trospium.
US20050244347A1 (en) * 2004-04-30 2005-11-03 Mehra Dev K Oral care products comprising calcium phosphates
US20050244343A1 (en) * 2004-04-30 2005-11-03 Withiam Michael C Oral care products comprising silica
US20070196477A1 (en) * 2004-04-30 2007-08-23 Withiam Michael C Rapidly dissolving tablets comprising low surface area calcium phosphates
DE102004023930A1 (de) * 2004-05-12 2005-12-08 Boehringer Ingelheim Vetmedica Gmbh Schnell lösliches Granulat von Bromhexin/Bromhexinhydrochlorid, Verfahren zu dessen Herstellung und dessen Verwendung
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
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US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
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MY149082A (en) * 2005-12-28 2013-07-15 Meiji Co Ltd Solid milk and method of making the same
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US20080260823A1 (en) * 2007-04-20 2008-10-23 Sciele Pharma, Inc. Orally disintegrating tablet comprising glycopyrrolate for treating sialorrhea
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KR101352689B1 (ko) * 2012-12-31 2014-01-17 (주) 에프엔지리서치 불연속상과 연속상으로 이루어지는 응집단위를 포함하는 마이크로그래뉼 제형

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Also Published As

Publication number Publication date
US5837285A (en) 1998-11-17
KR950700052A (ko) 1995-01-16
EP0627218A4 (de) 1995-06-14
DE69331378D1 (de) 2002-01-31
EP0627218A1 (de) 1994-12-07
KR100286505B1 (ko) 2001-04-16
EP0627218B1 (de) 2001-12-19
WO1993015724A1 (en) 1993-08-19
CA2130487A1 (en) 1993-08-19
ATE210968T1 (de) 2002-01-15

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