DE60336887D1 - Verbindungen für die modulation der proliferation von zellen - Google Patents
Verbindungen für die modulation der proliferation von zellenInfo
- Publication number
- DE60336887D1 DE60336887D1 DE60336887T DE60336887T DE60336887D1 DE 60336887 D1 DE60336887 D1 DE 60336887D1 DE 60336887 T DE60336887 T DE 60336887T DE 60336887 T DE60336887 T DE 60336887T DE 60336887 D1 DE60336887 D1 DE 60336887D1
- Authority
- DE
- Germany
- Prior art keywords
- 6alkyl
- compounds
- proliferation
- modulation
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
- C07C255/41—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by carboxyl groups, other than cyano groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
- C07D213/71—Sulfur atoms to which a second hetero atom is attached
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34921602P | 2002-01-18 | 2002-01-18 | |
US34921402P | 2002-01-18 | 2002-01-18 | |
US34921502P | 2002-01-18 | 2002-01-18 | |
PCT/CA2003/000032 WO2003062190A1 (en) | 2002-01-18 | 2003-01-17 | Compounds for modulating cell proliferation |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60336887D1 true DE60336887D1 (de) | 2011-06-09 |
Family
ID=27617577
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60336887T Expired - Lifetime DE60336887D1 (de) | 2002-01-18 | 2003-01-17 | Verbindungen für die modulation der proliferation von zellen |
Country Status (11)
Country | Link |
---|---|
US (1) | US7563820B2 (de) |
EP (1) | EP1467967B1 (de) |
JP (1) | JP4383885B2 (de) |
CN (1) | CN1633411A (de) |
AT (1) | ATE507203T1 (de) |
BR (1) | BR0307000A (de) |
CA (1) | CA2473763A1 (de) |
DE (1) | DE60336887D1 (de) |
GB (1) | GB2401363B (de) |
MX (1) | MXPA04006920A (de) |
WO (1) | WO2003062190A1 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0307000A (pt) | 2002-01-18 | 2004-11-03 | Hospital For Sick Children | Compostos para modulação de proliferação celular |
EP1551381A2 (de) * | 2002-10-11 | 2005-07-13 | The Hospital for Sick Children | Styrol-acrylnitril derivate zur hemmung des vaskulären endothelischen wachstumsfaktors |
CH696238A5 (de) * | 2003-06-30 | 2007-02-28 | Lymphosign Inc | Verfahren zur Herstellung von Zimtaldehydverbindungen. |
CA2533287A1 (en) * | 2003-07-30 | 2005-02-10 | The Hospital For Sick Children | Compounds for modulating cell proliferation |
US7598419B2 (en) | 2004-03-26 | 2009-10-06 | Hsc Research And Development Limited Partnership | Compounds for modulating cell proliferation |
US7807719B2 (en) | 2004-09-14 | 2010-10-05 | Chaim Roifman | Compounds useful for modulating abnormal cell proliferation |
US7202383B2 (en) | 2004-09-14 | 2007-04-10 | The Hospital For Sick Children | Compounds useful for modulating abnormal cell proliferation |
WO2007006143A1 (en) * | 2005-07-13 | 2007-01-18 | The Hospital For Sick Children | Compositions and methods for detecting transformed cells |
KR102079160B1 (ko) * | 2009-12-10 | 2020-02-19 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 아밀로이드 결합제 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3718472A (en) * | 1971-03-04 | 1973-02-27 | Eastman Kodak Co | Filter dyes for photographic elements |
US4632895A (en) * | 1984-08-23 | 1986-12-30 | Minnesota Mining And Manufacturing Company | Diffusion or sublimation transfer imaging system |
GB8421398D0 (en) | 1984-08-23 | 1984-09-26 | Minnesota Mining & Mfg | Sublimation transfer imaging system |
US4617373A (en) * | 1985-02-15 | 1986-10-14 | Eastman Kodak Company | Condensation polymers and products therefrom |
US5217999A (en) | 1987-12-24 | 1993-06-08 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Styryl compounds which inhibit EGF receptor protein tyrosine kinase |
US5418245A (en) | 1990-04-16 | 1995-05-23 | Rhone-Poulenc Rorer International (Holdings) Inc. | Styryl-substituted monocyclic and bicyclic heteroaryl compounds which inhibit EGF receptor tyrosine kinase |
WO1995024190A2 (en) | 1994-03-07 | 1995-09-14 | Sugen, Inc. | Receptor tyrosine kinase inhibitors for inhibiting cell proliferative disorders and compositions thereof |
US5656655A (en) | 1994-03-17 | 1997-08-12 | Rhone-Poulenc Rorer Pharmaceuticals, Inc. | Styryl-substituted heteroaryl compounds which inhibit EGF receptor tyrosine kinase |
AU6112896A (en) | 1995-06-07 | 1996-12-30 | Sugen, Inc. | Tyrphostin-like compounds for the treatment of cell prolifer ative disorders or cell differentiation disorders |
JP2001066605A (ja) | 1999-08-30 | 2001-03-16 | Hayashi Telempu Co Ltd | 液晶配向膜およびその製造方法、液晶表示装置 |
AU4820101A (en) * | 2000-04-13 | 2001-10-30 | Hsc Res Dev Lp | Novel compounds for modulating cell proliferation |
BR0307000A (pt) | 2002-01-18 | 2004-11-03 | Hospital For Sick Children | Compostos para modulação de proliferação celular |
-
2003
- 2003-01-17 BR BR0307000-0A patent/BR0307000A/pt not_active IP Right Cessation
- 2003-01-17 CA CA002473763A patent/CA2473763A1/en not_active Abandoned
- 2003-01-17 WO PCT/CA2003/000032 patent/WO2003062190A1/en active Application Filing
- 2003-01-17 US US10/501,699 patent/US7563820B2/en not_active Expired - Fee Related
- 2003-01-17 MX MXPA04006920A patent/MXPA04006920A/es active IP Right Grant
- 2003-01-17 JP JP2003562074A patent/JP4383885B2/ja not_active Expired - Lifetime
- 2003-01-17 GB GB0418331A patent/GB2401363B/en not_active Expired - Fee Related
- 2003-01-17 AT AT03700255T patent/ATE507203T1/de not_active IP Right Cessation
- 2003-01-17 EP EP03700255A patent/EP1467967B1/de not_active Expired - Lifetime
- 2003-01-17 CN CNA038040646A patent/CN1633411A/zh active Pending
- 2003-01-17 DE DE60336887T patent/DE60336887D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1467967A1 (de) | 2004-10-20 |
GB2401363B (en) | 2005-10-12 |
CA2473763A1 (en) | 2003-07-31 |
JP4383885B2 (ja) | 2009-12-16 |
ATE507203T1 (de) | 2011-05-15 |
CN1633411A (zh) | 2005-06-29 |
BR0307000A (pt) | 2004-11-03 |
EP1467967B1 (de) | 2011-04-27 |
US20050085538A1 (en) | 2005-04-21 |
US7563820B2 (en) | 2009-07-21 |
GB0418331D0 (en) | 2004-09-22 |
MXPA04006920A (es) | 2005-06-17 |
JP2005515252A (ja) | 2005-05-26 |
GB2401363A (en) | 2004-11-10 |
WO2003062190A1 (en) | 2003-07-31 |
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