DE60329237D1 - Kristalline form von linezolid - Google Patents
Kristalline form von linezolidInfo
- Publication number
- DE60329237D1 DE60329237D1 DE60329237T DE60329237T DE60329237D1 DE 60329237 D1 DE60329237 D1 DE 60329237D1 DE 60329237 T DE60329237 T DE 60329237T DE 60329237 T DE60329237 T DE 60329237T DE 60329237 D1 DE60329237 D1 DE 60329237D1
- Authority
- DE
- Germany
- Prior art keywords
- linezolid
- crystalline form
- preparation
- relates
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- TYZROVQLWOKYKF-ZDUSSCGKSA-N linezolid Chemical compound O=C1O[C@@H](CNC(=O)C)CN1C(C=C1F)=CC=C1N1CCOCC1 TYZROVQLWOKYKF-ZDUSSCGKSA-N 0.000 title abstract 2
- 229960003907 linezolid Drugs 0.000 title abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Photoreceptors In Electrophotography (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IN2003/000336 WO2005035530A1 (en) | 2003-10-16 | 2003-10-16 | A novel crystalline form of linezolid |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60329237D1 true DE60329237D1 (de) | 2009-10-22 |
Family
ID=34430675
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE2009163348 Pending DE09163348T1 (de) | 2003-10-16 | 2003-10-16 | Kristalline Form von Linezolid |
DE60329237T Expired - Lifetime DE60329237D1 (de) | 2003-10-16 | 2003-10-16 | Kristalline form von linezolid |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE2009163348 Pending DE09163348T1 (de) | 2003-10-16 | 2003-10-16 | Kristalline Form von Linezolid |
Country Status (10)
Country | Link |
---|---|
US (4) | US7714128B2 (de) |
EP (3) | EP2902386B1 (de) |
AT (1) | ATE442364T1 (de) |
AU (1) | AU2003278592A1 (de) |
DE (2) | DE09163348T1 (de) |
DK (1) | DK1673370T3 (de) |
ES (3) | ES2803516T3 (de) |
HU (1) | HUE051230T2 (de) |
PT (1) | PT1673370E (de) |
WO (1) | WO2005035530A1 (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2803516T3 (es) | 2003-10-16 | 2021-01-27 | Symed Labs Ltd | Una forma cristalina de linezolid |
WO2005099353A2 (en) | 2004-04-19 | 2005-10-27 | Symed Labs Limited | A novel process for the preparation of linezolid and related compounds |
US20060142283A1 (en) * | 2004-06-29 | 2006-06-29 | Judith Aronhime | Crystalline form IV of linezolid |
US20060111350A1 (en) * | 2004-06-29 | 2006-05-25 | Judith Aronhime | Solid forms of linezolid and processes for preparation thereof |
WO2006091731A2 (en) * | 2005-02-24 | 2006-08-31 | Teva Pharmaceutical Industries Ltd. | Processes for the preparation of linezolid intermediate |
DK1749517T3 (da) * | 2005-07-20 | 2008-11-03 | Teva Pharma | Stabil farmaceutiske sammensætning af linezolid form IV |
EP2033960A3 (de) | 2007-09-04 | 2009-04-29 | Dipharma Francis S.r.l. | Kristalline Linezolidhydratform und Linezolidsalze |
IT1390957B1 (it) * | 2008-07-07 | 2011-10-27 | Dipharma Francis Srl | Sali di linezolid e loro uso nella preparazione di forme cristalline di linezolid |
US20090093631A1 (en) * | 2007-09-06 | 2009-04-09 | Ben-Zion Dolitzky | Processes for the preparation of a linezolid intermediate, linezolid hydroxide |
WO2009140466A2 (en) * | 2008-05-14 | 2009-11-19 | Dr. Reddy's Laboratories Ltd. | Linezolid co-crystals |
EP2493867A1 (de) | 2009-10-28 | 2012-09-05 | Synthon BV | Verfahren zur herstellung einer kristallinen form von linezolid |
WO2011050826A1 (en) * | 2009-10-28 | 2011-05-05 | Synthon B.V. | Process for making crystalline form a of linezolid |
EP2516408A1 (de) | 2009-12-26 | 2012-10-31 | Alembic Pharmaceuticals Limited | Verfahren zur herstellung von linezolid |
CN103140487A (zh) | 2010-08-11 | 2013-06-05 | 斯索恩有限公司 | 制备利奈唑胺的方法 |
EP2690100A1 (de) | 2010-08-11 | 2014-01-29 | Synhton B.V. | Verfahren zur Linezpolid Herstellung |
WO2012029074A2 (en) | 2010-09-02 | 2012-03-08 | Hetero Research Foundation | Pharmaceutical compositions of linezolid |
CN102070548B (zh) * | 2011-01-13 | 2012-12-26 | 浙江新东港药业股份有限公司 | 一种晶型ⅰ型利奈唑胺的蒸发结晶工艺 |
WO2012114354A1 (en) | 2011-02-24 | 2012-08-30 | Lee Pharma Limited | Anhydrous linezolid crystalline form-ii |
WO2012119653A1 (en) | 2011-03-09 | 2012-09-13 | Synthon Bv | Process for making crystalline form a of linezolid |
CN102766106A (zh) * | 2011-05-03 | 2012-11-07 | 江苏豪森医药集团有限公司 | 利奈唑胺的新晶型及其制备方法 |
ITMI20111311A1 (it) * | 2011-07-14 | 2013-01-15 | Dipharma Francis Srl | Sali di linezolid e loro uso nella preparazione di forme cristalline di linezolid |
WO2013072923A1 (en) | 2011-09-19 | 2013-05-23 | Cadila Healthcare Limited | Process for the preparation of crystalline linezolid |
WO2013093751A1 (en) * | 2011-12-24 | 2013-06-27 | Alembic Pharmaceuticals Limited | Packaging for linezolid |
EP2852580A1 (de) | 2012-01-24 | 2015-04-01 | Jubilant Life Sciences Ltd. | Verbessertes verfahren zur herstellung von stabiler kristalliner form-i von linezolid, im wesentlichen frei von lösungsmittelresten |
WO2013120496A1 (en) | 2012-02-14 | 2013-08-22 | Pharmathen S.A. | Process for the preparation of linezolid in crystalline form and salts thereof |
WO2013190559A1 (en) * | 2012-06-19 | 2013-12-27 | Symed Labs Limited | Improved processes for the preparation of linezolid crystalline form iii |
US9492459B2 (en) * | 2012-08-10 | 2016-11-15 | Indoco Remedies Limited | Pharmaceutical composition of linezolid |
WO2014071990A1 (en) | 2012-11-09 | 2014-05-15 | Synthon Bv | Process for making linezolid |
WO2014118809A1 (en) | 2013-01-29 | 2014-08-07 | Actavis Group Ptc Ehf. | Pharmaceutical composition with linezolid |
IN2013MU03508A (de) | 2013-11-06 | 2015-07-24 | Unimark Remedies Ltd | |
CN105254580B (zh) * | 2014-04-22 | 2018-01-02 | 江苏豪森药业集团有限公司 | 利奈唑胺晶型的制备方法 |
IN2015CH00214A (de) * | 2015-01-13 | 2015-04-24 | Nosch Labs Private Ltd | |
WO2018051360A1 (en) * | 2016-09-16 | 2018-03-22 | Lee Pharma Limited | A novel process for the preparation of crystalline linezolid form-iii |
SG11202003537TA (en) | 2017-11-16 | 2020-05-28 | Persica Pharmaceuticals Ltd | Linezolid formulations |
CN110194750A (zh) * | 2019-06-19 | 2019-09-03 | 四川美大康华康药业有限公司 | 一种利奈唑胺的制备方法及精制方法 |
WO2023062080A1 (en) | 2021-10-12 | 2023-04-20 | Persica Pharmaceuticals Ltd. | Low back pain treatment |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US583870A (en) * | 1897-06-01 | Wrench | ||
DE2810349A1 (de) | 1978-03-10 | 1979-09-20 | Kali Chemie Pharma Gmbh | Verfahren zur herstellung von 3-hydroxy-6-phenyl-1,2,3,4-tetrahydro- 1,5-benzodiazocinen |
FR2506769A2 (fr) | 1978-06-09 | 1982-12-03 | Delalande Sa | Para-((cyano-5 n pentyl-1) phenyl)-3 methoxymethyl-5 oxazolidinone-2, son procede de preparation et ses applications en therapeutique |
US4340606A (en) | 1980-10-23 | 1982-07-20 | E. I. Du Pont De Nemours And Company | 3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents |
FR2608604B1 (fr) | 1986-12-19 | 1989-04-28 | Delalande Sa | Derives 5-hydroxyethyles de l'oxazolidinone-2, leurs procedes de preparation et leurs applications en therapeutique |
US5006528A (en) | 1988-10-31 | 1991-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
DE9310451U1 (de) | 1993-03-05 | 1994-06-30 | Landis & Gyr Business Support Ag, Zug | Steuer- bzw. Regeleinrichtung für Gas-Feuerungsautomaten von Heizungsanlagen |
EP0615095B1 (de) | 1993-03-11 | 1997-05-07 | Landis & Gyr Technology Innovation AG | Brennerregler |
MY115155A (en) | 1993-09-09 | 2003-04-30 | Upjohn Co | Substituted oxazine and thiazine oxazolidinone antimicrobials. |
US5688792A (en) | 1994-08-16 | 1997-11-18 | Pharmacia & Upjohn Company | Substituted oxazine and thiazine oxazolidinone antimicrobials |
SK284703B6 (sk) | 1996-04-11 | 2005-09-08 | Pharmacia & Upjohn Company | Spôsob prípravy substituovaných oxazolidinón alkoholov |
EP0890791A1 (de) | 1997-07-11 | 1999-01-13 | Electrowatt Technology Innovation AG | Steuer- und Regelgerät für einen Brenner |
KR100580408B1 (ko) | 1997-11-07 | 2006-05-16 | 파마시아 앤드 업존 캄파니 엘엘씨 | 옥사졸리디논의 제조 방법 |
US6444813B2 (en) * | 2000-02-02 | 2002-09-03 | Pharmacia & Upjohn Company | Linezolid-crystal form II |
AR027261A1 (es) | 2000-02-02 | 2003-03-19 | Upjohn Co | Linezolid forma cristalina ii |
MY127336A (en) | 2000-03-22 | 2006-11-30 | Upjohn Co | Container for linezolid iv solution |
DE10037585A1 (de) * | 2000-08-02 | 2002-02-14 | Valeo Schalter & Sensoren Gmbh | Rückstellvorrichtung für einen Blinkerschalter in Kraftfahrzeugen |
WO2002014286A1 (en) * | 2000-08-14 | 2002-02-21 | Teva Pharmaceutical Industries Ltd. | Preparation of risperidone |
JP2004520432A (ja) * | 2001-02-05 | 2004-07-08 | ファルマシア・アンド・アップジョン・カンパニー | オキサゾリジノン抗菌薬の直腸送達のための組成物 |
JP2005504007A (ja) | 2001-04-20 | 2005-02-10 | ファルマシア アンド アップジョン カンパニー リミティド ライアビリティー カンパニー | オキサゾリジノンの製法 |
CN1155585C (zh) | 2001-12-19 | 2004-06-30 | 中国医学科学院医药生物技术研究所 | 3,5-取代噁唑烷酮衍生物及其制备方法和应用 |
US6992219B2 (en) * | 2002-08-09 | 2006-01-31 | Cephalon France | Modafinil polymorphic forms |
ES2803516T3 (es) | 2003-10-16 | 2021-01-27 | Symed Labs Ltd | Una forma cristalina de linezolid |
WO2005099353A2 (en) | 2004-04-19 | 2005-10-27 | Symed Labs Limited | A novel process for the preparation of linezolid and related compounds |
US20060142283A1 (en) * | 2004-06-29 | 2006-06-29 | Judith Aronhime | Crystalline form IV of linezolid |
US7429661B2 (en) | 2004-07-20 | 2008-09-30 | Symed Labs Limited | Intermediates for linezolid and related compounds |
-
2003
- 2003-10-16 ES ES15155714T patent/ES2803516T3/es not_active Expired - Lifetime
- 2003-10-16 DK DK03769887T patent/DK1673370T3/da active
- 2003-10-16 HU HUE15155714A patent/HUE051230T2/hu unknown
- 2003-10-16 EP EP15155714.7A patent/EP2902386B1/de not_active Expired - Lifetime
- 2003-10-16 AT AT03769887T patent/ATE442364T1/de active
- 2003-10-16 ES ES03769887T patent/ES2331001T3/es not_active Expired - Lifetime
- 2003-10-16 US US10/524,478 patent/US7714128B2/en active Active
- 2003-10-16 DE DE2009163348 patent/DE09163348T1/de active Pending
- 2003-10-16 WO PCT/IN2003/000336 patent/WO2005035530A1/en active Application Filing
- 2003-10-16 PT PT03769887T patent/PT1673370E/pt unknown
- 2003-10-16 ES ES09163348T patent/ES2331454T1/es active Pending
- 2003-10-16 DE DE60329237T patent/DE60329237D1/de not_active Expired - Lifetime
- 2003-10-16 AU AU2003278592A patent/AU2003278592A1/en not_active Abandoned
- 2003-10-16 EP EP03769887A patent/EP1673370B1/de not_active Revoked
- 2003-10-16 EP EP20090163348 patent/EP2100884A1/de not_active Withdrawn
-
2007
- 2007-09-26 US US11/861,340 patent/US7718799B2/en not_active Expired - Fee Related
- 2007-09-26 US US11/861,433 patent/US7718800B2/en not_active Expired - Fee Related
- 2007-09-26 US US11/861,406 patent/US7732597B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES2331001T3 (es) | 2009-12-18 |
EP2100884A1 (de) | 2009-09-16 |
WO2005035530A1 (en) | 2005-04-21 |
ATE442364T1 (de) | 2009-09-15 |
US7714128B2 (en) | 2010-05-11 |
ES2803516T3 (es) | 2021-01-27 |
DE09163348T1 (de) | 2010-01-07 |
US7718799B2 (en) | 2010-05-18 |
US20080091011A1 (en) | 2008-04-17 |
US7718800B2 (en) | 2010-05-18 |
EP2902386A1 (de) | 2015-08-05 |
EP1673370B1 (de) | 2009-09-09 |
EP1673370A1 (de) | 2006-06-28 |
PT1673370E (pt) | 2009-11-05 |
US7732597B2 (en) | 2010-06-08 |
HUE051230T2 (hu) | 2021-03-01 |
DK1673370T3 (da) | 2009-12-07 |
EP2902386B1 (de) | 2020-04-08 |
AU2003278592A1 (en) | 2005-04-27 |
US20080090820A1 (en) | 2008-04-17 |
US20080090824A1 (en) | 2008-04-17 |
ES2331454T1 (es) | 2010-01-05 |
US20060128703A1 (en) | 2006-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
R082 | Change of representative |
Ref document number: 1673370 Country of ref document: EP Representative=s name: LEDERER & KELLER, 80538 MUENCHEN, DE |