DE60322630D1 - Modifizierte Reduktase von Penicillium citrinum und das dafür kodierende Gen - Google Patents

Modifizierte Reduktase von Penicillium citrinum und das dafür kodierende Gen

Info

Publication number
DE60322630D1
DE60322630D1 DE60322630T DE60322630T DE60322630D1 DE 60322630 D1 DE60322630 D1 DE 60322630D1 DE 60322630 T DE60322630 T DE 60322630T DE 60322630 T DE60322630 T DE 60322630T DE 60322630 D1 DE60322630 D1 DE 60322630D1
Authority
DE
Germany
Prior art keywords
gene coding
penicillium citrinum
modified reductase
reductase
modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60322630T
Other languages
English (en)
Inventor
Hiroyuki Asako
Masatoshi Shimizu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Application granted granted Critical
Publication of DE60322630D1 publication Critical patent/DE60322630D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE60322630T 2002-07-02 2003-06-30 Modifizierte Reduktase von Penicillium citrinum und das dafür kodierende Gen Expired - Lifetime DE60322630D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2002193074A JP4228605B2 (ja) 2002-07-02 2002-07-02 改変型還元酵素、その遺伝子及びそれらの利用

Publications (1)

Publication Number Publication Date
DE60322630D1 true DE60322630D1 (de) 2008-09-18

Family

ID=29720245

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60322630T Expired - Lifetime DE60322630D1 (de) 2002-07-02 2003-06-30 Modifizierte Reduktase von Penicillium citrinum und das dafür kodierende Gen

Country Status (4)

Country Link
US (1) US7135318B2 (de)
EP (1) EP1378566B1 (de)
JP (1) JP4228605B2 (de)
DE (1) DE60322630D1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010227023A (ja) * 2009-03-27 2010-10-14 Asahi Kasei Chemicals Corp Ｎａｄｈ／ｎａｄ比の制御による２−デオキシ−シロ−イノソースの製造方法
CN113881647B (zh) * 2020-12-28 2023-11-17 上海合全药物研发有限公司 转氨酶及其在制备光学纯手性胺中的应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US186400A (en) * 1877-01-16 Improvement in indicators for drawing liquids from bottles
US4455373A (en) * 1980-08-01 1984-06-19 Imperial Chemical Industries Plc Microbiological oxidations
JPS60251890A (ja) 1984-05-30 1985-12-12 Nippon Synthetic Chem Ind Co Ltd:The γ−ハロ−β−ヒドロキシ酪酸エステルの製造法
US5233095A (en) * 1986-03-18 1993-08-03 Catalytica, Inc. Process for manufacture of resorcinol
JPS63123387A (ja) 1986-11-13 1988-05-27 Denki Kagaku Kogyo Kk γ−ハロ−β−ヒドロキシ酪酸エステルの製造法
JP2566962B2 (ja) 1987-06-11 1996-12-25 電気化学工業株式会社 γ−置換−β−ハイドロキシ酪酸エステルの製造法
JPH0678277B2 (ja) * 1988-02-19 1994-10-05 高砂香料工業株式会社 光学活性アルコールおよびその誘導体の製造方法
JPH01222787A (ja) 1988-02-29 1989-09-06 Nippon Synthetic Chem Ind Co Ltd:The β−ケト酸類の還元方法
JPH02312593A (ja) 1989-05-26 1990-12-27 Daito Koeki Kk パン酵母によるケトン類の不斉還元反応方法
JP2532299B2 (ja) 1989-10-06 1996-09-11 富士レビオ株式会社 パントテン酸誘導体
US5215919A (en) * 1991-02-25 1993-06-01 Takeda Chemical Industries, Ltd. Process for producing optically active 2-hydroxycycloalkanecarboxylic acid esters using microbially derived reductase
JPH1094399A (ja) 1996-09-24 1998-04-14 Fukui Pref Gov Sangyo Shinko Zaidan 酵素を用いる光学活性アルコールの製造法
US5908953A (en) * 1996-12-18 1999-06-01 Mitsubishi Chemical Corporation Method for producing (R)-4-cyano-3-hydroxybutyric acid lower alkyl ester
KR100506134B1 (ko) * 1997-02-07 2005-08-08 카네카 코포레이션 신규한 카르보닐 환원효소 및 이것을 코딩하는 유전자 및 이러한 환원효소 및 유전자 이용방법
JP2000236883A (ja) * 1998-12-21 2000-09-05 Daicel Chem Ind Ltd 新規なカルボニル還元酵素、該酵素の製造方法、該酵素をコードするｄｎａおよびこれを利用したアルコールの製造方法
EP1134207A1 (de) 2000-03-15 2001-09-19 Pfizer Products Inc. Verfahren zur Herstellung von Resorcinolderivaten
EP1201647B1 (de) 2000-10-31 2004-09-22 Sumitomo Chemical Company, Limited Verfahren zur Herstellung von 4-Cyano-4-Oxobuttersäureester und 4-Cyano-3-Hydroxybuttersäureester
US6884607B2 (en) 2000-12-07 2005-04-26 Sumitomo Chemical Company, Limited Process for producing optically active 4-halo-3-hydroxybutanoate
JP2003250577A (ja) 2001-12-27 2003-09-09 Sumitomo Chem Co Ltd ２‐ヒドロキシシクロアルカンカルボン酸エステルの製造方法

Also Published As

Publication number Publication date
US7135318B2 (en) 2006-11-14
JP4228605B2 (ja) 2009-02-25
US20040091902A1 (en) 2004-05-13
EP1378566A2 (de) 2004-01-07
EP1378566B1 (de) 2008-08-06
EP1378566A3 (de) 2004-01-14
JP2004033074A (ja) 2004-02-05

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