DE60321730D1 - Agonisten des corticotropin-freisetzenden Faktor Rezeptors 2 - Google Patents

Agonisten des corticotropin-freisetzenden Faktor Rezeptors 2

Info

Publication number
DE60321730D1
DE60321730D1 DE60321730T DE60321730T DE60321730D1 DE 60321730 D1 DE60321730 D1 DE 60321730D1 DE 60321730 T DE60321730 T DE 60321730T DE 60321730 T DE60321730 T DE 60321730T DE 60321730 D1 DE60321730 D1 DE 60321730D1
Authority
DE
Germany
Prior art keywords
agonists
factor receptor
releasing factor
corticotropin releasing
corticotropin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60321730T
Other languages
English (en)
Inventor
Robert Isfort
Wieslaw Mazur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Chilcott Co LLC
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Application granted granted Critical
Publication of DE60321730D1 publication Critical patent/DE60321730D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57509Corticotropin releasing factor [CRF] (Urotensin)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE60321730T 2002-01-16 2003-01-16 Agonisten des corticotropin-freisetzenden Faktor Rezeptors 2 Expired - Lifetime DE60321730D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US34911702P 2002-01-16 2002-01-16
US37633702P 2002-04-29 2002-04-29
US38889502P 2002-06-14 2002-06-14
US41198802P 2002-09-19 2002-09-19

Publications (1)

Publication Number Publication Date
DE60321730D1 true DE60321730D1 (de) 2008-07-31

Family

ID=27617822

Family Applications (4)

Application Number Title Priority Date Filing Date
DE60321730T Expired - Lifetime DE60321730D1 (de) 2002-01-16 2003-01-16 Agonisten des corticotropin-freisetzenden Faktor Rezeptors 2
DE60313845T Expired - Lifetime DE60313845T2 (de) 2002-01-16 2003-01-16 Agonisten des corticotropin-freisetzenden faktor rezeptors 2
DE60318547T Expired - Lifetime DE60318547T2 (de) 2002-01-16 2003-01-16 Agonisten des corticotropin-freisetzenden faktor rezeptors 2
DE60307044T Expired - Lifetime DE60307044T2 (de) 2002-01-16 2003-01-16 Agonisten des corticotropin-freisetzenden faktor rezeptors 2

Family Applications After (3)

Application Number Title Priority Date Filing Date
DE60313845T Expired - Lifetime DE60313845T2 (de) 2002-01-16 2003-01-16 Agonisten des corticotropin-freisetzenden faktor rezeptors 2
DE60318547T Expired - Lifetime DE60318547T2 (de) 2002-01-16 2003-01-16 Agonisten des corticotropin-freisetzenden faktor rezeptors 2
DE60307044T Expired - Lifetime DE60307044T2 (de) 2002-01-16 2003-01-16 Agonisten des corticotropin-freisetzenden faktor rezeptors 2

Country Status (30)

Country Link
US (7) US6936585B2 (de)
EP (4) EP1465922B1 (de)
JP (3) JP4508648B2 (de)
KR (3) KR100735586B1 (de)
CN (3) CN100475844C (de)
AR (3) AR038143A1 (de)
AT (4) ATE398632T1 (de)
AU (2) AU2003205197B2 (de)
BR (3) BR0306838A (de)
CA (3) CA2470731C (de)
CY (1) CY1106133T1 (de)
DE (4) DE60321730D1 (de)
DK (2) DK1465921T3 (de)
ES (4) ES2299701T3 (de)
HK (1) HK1078095A1 (de)
IL (5) IL162530A0 (de)
MA (3) MA27592A1 (de)
MX (3) MXPA04006884A (de)
MY (1) MY140306A (de)
NO (3) NO20043366L (de)
NZ (3) NZ533598A (de)
PE (3) PE20030849A1 (de)
PL (3) PL371364A1 (de)
PT (2) PT1465921E (de)
RU (1) RU2294333C2 (de)
SA (3) SA03230565B1 (de)
SI (1) SI1465921T1 (de)
TW (3) TWI300442B (de)
WO (3) WO2003062277A1 (de)
ZA (1) ZA200404995B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2427490A1 (en) * 2000-09-22 2002-03-28 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Methods for improving the antagonistic/agonistic properties of peptidic antagonists/agonists of the corticotropin-releasing factor receptor (crfr)
US6936585B2 (en) * 2002-01-16 2005-08-30 The Procter & Gamble Company Corticotropin releasing factor 2 receptor agonists
WO2005103690A2 (en) * 2004-04-24 2005-11-03 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with corticotropin releasing hormone receptor 2 (crhr2)
EP1871888A4 (de) * 2005-03-30 2013-08-21 Novartis Vaccines & Diagnostic Haemophilus-influenzae vom typ b
WO2007090087A2 (en) * 2006-01-27 2007-08-09 Research Development Foundation Use of corticotropin releasing factor receptor-2 inhibitors for treating insulin-related diseases
US20100216722A1 (en) * 2007-09-11 2010-08-26 Dorian Bevec Use of the peptide pro-gly-thr-cys-glu-ile-cys-ala-tyr-ala-ala-cys-thr-gly-cys as a therapeutic agent
RU2010114038A (ru) * 2007-09-11 2011-10-20 Мондобайотек Лабораториз Аг (Li) Применение адреномедуллина в качестве терапевтического средства для лечения избыточного ангиогенеза
WO2009046874A1 (en) * 2007-09-11 2009-04-16 Mondobiotech Laboratories Ag Therapeutic combination of trh-potentiating peptide and stresscopin
AU2009313619A1 (en) 2008-11-04 2010-05-14 Janssen Pharmaceutica Nv CRHR2 peptide agonists and uses thereof
EP2206726A1 (de) * 2009-01-08 2010-07-14 Universite Joseph Fourier Nichtinvasive Instrumente zum Nachweisen anfälliger atherosklerotischer Plaques
AU2010315131A1 (en) * 2009-11-04 2012-05-31 Janssen Pharmaceutica Nv Method for treating heart failure with stresscopin-like peptides
US9314506B2 (en) 2011-10-24 2016-04-19 Research Development Foundation Methods for increasing insulin secretion by co-stimulation of corticotropin-releasing factor receptors
HUE036640T2 (hu) * 2012-02-14 2018-07-30 Univ California Parakrin gének szisztémás bejuttatása és szabályozott expressziója szív és érrendszeri betegségekre és egyéb állapotokra
JOP20170153A1 (ar) * 2016-07-15 2019-01-30 Lilly Co Eli نظائر urocortin-2 جديدة معدلة بحمض دهني لعلاج داء السكري وأمراض الكلى المزمنة
CA3040889A1 (en) * 2016-10-20 2018-04-26 Cortene Inc. Methods of treating diseases resulting from a maladapted stress response
CN110755434B (zh) * 2018-07-27 2022-03-15 中国医学科学院药物研究所 化合物palosuran防治骨骼肌萎缩等疾病的用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5235036A (en) * 1991-05-31 1993-08-10 The Salk Institute For Biological Studies Crf analogs
EP0860501A3 (de) 1994-06-14 1999-05-19 Neurocrine Biosciences, Inc. Corticotropin freisetzende Rezeptoren des Faktor 2
US5786203A (en) * 1994-06-14 1998-07-28 Neurocrine Biosciences, Inc. Isolated nucleic acid encoding corticotropin-releasing factor2 receptors
US5663292A (en) * 1994-12-12 1997-09-02 The Salk Institute For Biological Studies Cyclic CRF analogs
US5824771A (en) * 1994-12-12 1998-10-20 The Salk Institute For Biological Studies Cyclic CRF agonists
US5660824A (en) 1995-05-24 1997-08-26 Grabstein; Kenneth H. Muscle trophic factor
WO1997000063A2 (en) 1995-06-13 1997-01-03 The Salk Institute For Biological Studies Urocortin peptides
US5869450A (en) * 1996-03-06 1999-02-09 The Regents Of The University Of California Anti-inflammatory compositions and method with corticotropin-releasing factor analogs
EP1305334B1 (de) 2000-08-04 2008-09-17 Research Development Foundation Urocortinproteine und deren verwendungen
US20020082409A1 (en) 2000-10-26 2002-06-27 Hsu Sheau Yu Stresscopins and their uses
US6670140B2 (en) * 2001-03-06 2003-12-30 The Procter & Gamble Company Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors
US6936585B2 (en) 2002-01-16 2005-08-30 The Procter & Gamble Company Corticotropin releasing factor 2 receptor agonists

Also Published As

Publication number Publication date
US7632933B2 (en) 2009-12-15
CA2470743A1 (en) 2003-07-31
HK1078095A1 (en) 2006-03-03
EP1724283A3 (de) 2007-04-11
DE60313845D1 (de) 2007-06-28
WO2003062268A3 (en) 2003-11-27
US20100197579A1 (en) 2010-08-05
US20060025339A1 (en) 2006-02-02
CA2470731A1 (en) 2003-07-31
PE20030974A1 (es) 2003-12-26
IL162530A0 (en) 2005-11-20
JP4508649B2 (ja) 2010-07-21
JP2005525101A (ja) 2005-08-25
SA03230564B1 (ar) 2006-10-31
KR100758858B1 (ko) 2007-09-14
DK1465921T3 (da) 2006-11-27
NZ533600A (en) 2007-02-23
ES2269976T3 (es) 2007-04-01
EP1465922A2 (de) 2004-10-13
MA27592A1 (fr) 2005-11-01
BR0306826A (pt) 2005-09-06
IL197774A0 (en) 2009-12-24
US20030148956A1 (en) 2003-08-07
EP1465921A2 (de) 2004-10-13
US20090124793A1 (en) 2009-05-14
US20030148958A1 (en) 2003-08-07
SA03230565B1 (ar) 2006-10-31
CY1106133T1 (el) 2011-06-08
KR20040082392A (ko) 2004-09-24
ATE362488T1 (de) 2007-06-15
NO20043366L (no) 2004-10-06
AR038143A1 (es) 2004-12-29
BR0306878A (pt) 2004-10-26
US7192924B2 (en) 2007-03-20
CA2470731C (en) 2011-06-21
PL371364A1 (en) 2005-06-13
PL373529A1 (en) 2005-09-05
BR0306838A (pt) 2005-04-05
AU2003205197B2 (en) 2006-03-02
CA2470743C (en) 2011-12-13
ATE398632T1 (de) 2008-07-15
EP1465923B1 (de) 2007-05-16
IL162431A0 (en) 2005-11-20
NZ533598A (en) 2007-03-30
WO2003062269A3 (en) 2003-11-06
PL373139A1 (en) 2005-08-22
US7462597B2 (en) 2008-12-09
ES2309909T3 (es) 2008-12-16
KR20040082389A (ko) 2004-09-24
PT1465921E (pt) 2006-12-29
CN100391972C (zh) 2008-06-04
JP4508648B2 (ja) 2010-07-21
US7897731B2 (en) 2011-03-01
US20030148957A1 (en) 2003-08-07
SA03230565A (ar) 2005-12-03
JP2005522191A (ja) 2005-07-28
CN1617887A (zh) 2005-05-18
WO2003062277A1 (en) 2003-07-31
CN100475844C (zh) 2009-04-08
EP1724283A2 (de) 2006-11-22
WO2003062268A2 (en) 2003-07-31
IL162529A0 (en) 2005-11-20
NO20043396L (no) 2004-10-06
MXPA04006884A (es) 2004-12-06
MXPA04006883A (es) 2004-12-06
CA2470656C (en) 2011-06-28
RU2004124847A (ru) 2005-04-20
EP1465921B1 (de) 2006-07-26
US7608701B2 (en) 2009-10-27
SA03230564A (ar) 2005-12-03
CN1617886A (zh) 2005-05-18
DE60307044T2 (de) 2007-02-15
PE20030849A1 (es) 2003-12-01
ATE383372T1 (de) 2008-01-15
DE60318547D1 (de) 2008-02-21
US6936585B2 (en) 2005-08-30
ES2299701T3 (es) 2008-06-01
KR100758857B1 (ko) 2007-09-14
MA27591A1 (fr) 2005-11-01
ZA200404995B (en) 2005-06-29
AR038142A1 (es) 2004-12-29
RU2294333C2 (ru) 2007-02-27
EP1724283B1 (de) 2008-06-18
CA2470656A1 (en) 2003-07-31
NO20043371L (no) 2004-10-06
AU2003237419B2 (en) 2006-04-13
MA27590A1 (fr) 2005-11-01
EP1465922B1 (de) 2008-01-09
EP1465923A1 (de) 2004-10-13
US7192923B2 (en) 2007-03-20
TW200302277A (en) 2003-08-01
DE60313845T2 (de) 2008-01-31
PT1465923E (pt) 2007-08-06
KR100735586B1 (ko) 2007-07-04
MXPA04006885A (es) 2004-12-06
ATE334147T1 (de) 2006-08-15
JP4489434B2 (ja) 2010-06-23
TW200302276A (en) 2003-08-01
KR20040082390A (ko) 2004-09-24
ES2287484T3 (es) 2007-12-16
AR038144A1 (es) 2004-12-29
US20080004435A1 (en) 2008-01-03
IL196384A0 (en) 2011-07-31
PE20030747A1 (es) 2003-10-23
DE60318547T2 (de) 2008-12-24
SI1465921T1 (sl) 2006-10-31
TWI300442B (en) 2008-09-01
WO2003062269A2 (en) 2003-07-31
TW200302278A (en) 2003-08-01
NZ533599A (en) 2007-03-30
DE60307044D1 (de) 2006-09-07
MY140306A (en) 2009-12-31
CN1617885A (zh) 2005-05-18
DK1465923T3 (da) 2007-07-02
JP2005521387A (ja) 2005-07-21

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Legal Events

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Owner name: WARNER CHILCOTT COMPANY, LLC, FAJARDO, P.R., US