ATE334147T1 - Agonisten des corticotropin-freisetzenden faktor rezeptors 2 - Google Patents

Agonisten des corticotropin-freisetzenden faktor rezeptors 2

Info

Publication number: ATE334147T1
Authority: AT; Austria
Prior art keywords: agonists; factor receptor; releasing factor; corticotropin releasing; corticotropin
Prior art date: 2002-01-16

Application number

AT03703867T

Other languages

English (en)

Inventor

Robert Joseph Isfort

Wieslaw Adam Mazur

Original Assignee

Procter & Gamble

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-01-16

Filing date

2003-01-16

Publication date

2006-08-15

2003-01-16 Application filed by Procter & Gamble filed Critical Procter & Gamble

2006-08-15 Application granted granted Critical

2006-08-15 Publication of ATE334147T1 publication Critical patent/ATE334147T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57509—Corticotropin releasing factor [CRF] (Urotensin)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Gastroenterology & Hepatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Molecular Biology (AREA)
Physical Education & Sports Medicine (AREA)
Toxicology (AREA)
Zoology (AREA)
Neurology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Immunology (AREA)
Epidemiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

AT03703867T 2002-01-16 2003-01-16 Agonisten des corticotropin-freisetzenden faktor rezeptors 2 ATE334147T1 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US34911702P	2002-01-16	2002-01-16
US37633702P	2002-04-29	2002-04-29
US38889502P	2002-06-14	2002-06-14
US41198802P	2002-09-19	2002-09-19

Publications (1)

Publication Number	Publication Date
ATE334147T1 true ATE334147T1 (de)	2006-08-15

Family

ID=27617822

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
AT06117810T ATE398632T1 (de)	2002-01-16	2003-01-16	Agonisten des corticotropin-freisetzenden faktor rezeptors 2
AT03703867T ATE334147T1 (de)	2002-01-16	2003-01-16	Agonisten des corticotropin-freisetzenden faktor rezeptors 2
AT03731963T ATE383372T1 (de)	2002-01-16	2003-01-16	Agonisten des corticotropin-freisetzenden faktor rezeptors 2
AT03731965T ATE362488T1 (de)	2002-01-16	2003-01-16	Agonisten des corticotropin-freisetzenden faktor rezeptors 2

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT06117810T ATE398632T1 (de)	2002-01-16	2003-01-16	Agonisten des corticotropin-freisetzenden faktor rezeptors 2

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
AT03731963T ATE383372T1 (de)	2002-01-16	2003-01-16	Agonisten des corticotropin-freisetzenden faktor rezeptors 2
AT03731965T ATE362488T1 (de)	2002-01-16	2003-01-16	Agonisten des corticotropin-freisetzenden faktor rezeptors 2

Country Status (30)

Country	Link
US (7)	US7192923B2 (de)
EP (4)	EP1465923B1 (de)
JP (3)	JP4489434B2 (de)
KR (3)	KR100758857B1 (de)
CN (3)	CN100391972C (de)
AR (3)	AR038142A1 (de)
AT (4)	ATE398632T1 (de)
AU (2)	AU2003205197B2 (de)
BR (3)	BR0306838A (de)
CA (3)	CA2470731C (de)
CY (1)	CY1106133T1 (de)
DE (4)	DE60321730D1 (de)
DK (2)	DK1465921T3 (de)
ES (4)	ES2287484T3 (de)
HK (1)	HK1078095A1 (de)
IL (5)	IL162431A0 (de)
MA (3)	MA27590A1 (de)
MX (3)	MXPA04006885A (de)
MY (1)	MY140306A (de)
NO (3)	NO20043371L (de)
NZ (3)	NZ533599A (de)
PE (3)	PE20030849A1 (de)
PL (3)	PL373139A1 (de)
PT (2)	PT1465921E (de)
RU (1)	RU2294333C2 (de)
SA (3)	SA03230564A (de)
SI (1)	SI1465921T1 (de)
TW (3)	TW200302278A (de)
WO (3)	WO2003062277A1 (de)
ZA (1)	ZA200404995B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040049009A1 (en) *	2000-09-22	2004-03-11	Klaus Eckart	Methods for improving the antagonistic/agonistic properties of peptidic antagonists/agonists of the corticotropin-releasing factor receptor (crfr)
US7192923B2 (en) *	2002-01-16	2007-03-20	The Procter & Gamble Company	Corticotropin releasing factor 2 receptor agonists
WO2005103690A2 (en) *	2004-04-24	2005-11-03	Bayer Healthcare Ag	Diagnostics and therapeutics for diseases associated with corticotropin releasing hormone receptor 2 (crhr2)
CN101687025A (zh) *	2005-03-30	2010-03-31	诺华疫苗和诊断公司	B型流感嗜血杆菌
US7815905B2 (en)	2006-01-27	2010-10-19	Research Development Foundation	Methods of increasing insulin sensitivity or decreasing insulin secretion by administering corticotropin releasing factor receptor-2 inhibitors
WO2009043481A2 (en) *	2007-09-11	2009-04-09	Mondobiotech Laboratories Ag	Use of a peptide as a therapeutic agent
WO2009033692A2 (en) *	2007-09-11	2009-03-19	Mondobiotech Laboratories Ag	Use of the peptides fibrinopeptide a and pyx-i as a therapeutic agents
WO2009046874A1 (en) *	2007-09-11	2009-04-16	Mondobiotech Laboratories Ag	Therapeutic combination of trh-potentiating peptide and stresscopin
JP2012508014A (ja)	2008-11-04	2012-04-05	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	Ｃｒｈｒ２ペプチド作動薬及びその使用
EP2206726A1 (de) *	2009-01-08	2010-07-14	Universite Joseph Fourier	Nichtinvasive Instrumente zum Nachweisen anfälliger atherosklerotischer Plaques
US20110105397A1 (en) *	2009-11-04	2011-05-05	Gengo Peter J	Method for treating heart failure with stresscopin-like peptides
WO2013063046A1 (en)	2011-10-24	2013-05-02	Research Development Foundation	Methods for increasing insulin secretion by co-stimulation of corticotropin-releasing factor receptors
ES2660492T3 (es) *	2012-02-14	2018-03-22	The Regents Of The University Of California	Administración sistémica y expresión regulada de genes paracrinos para enfermedades cardiovasculares y otras afecciones
JOP20170153A1 (ar) *	2016-07-15	2019-01-30	Lilly Co Eli	نظائر urocortin-2 جديدة معدلة بحمض دهني لعلاج داء السكري وأمراض الكلى المزمنة
MX2019004401A (es) *	2016-10-20	2019-09-26	Cortene Inc	Metodos de tratamiento y enfermedades resultantes de una respuesta de tension mal adaptada.
CN110755434B (zh) *	2018-07-27	2022-03-15	中国医学科学院药物研究所	化合物palosuran防治骨骼肌萎缩等疾病的用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5235036A (en)	1991-05-31	1993-08-10	The Salk Institute For Biological Studies	Crf analogs
US5786203A (en)	1994-06-14	1998-07-28	Neurocrine Biosciences, Inc.	Isolated nucleic acid encoding corticotropin-releasing factor2 receptors
EP0860501A3 (de)	1994-06-14	1999-05-19	Neurocrine Biosciences, Inc.	Corticotropin freisetzende Rezeptoren des Faktor 2
US5824771A (en)	1994-12-12	1998-10-20	The Salk Institute For Biological Studies	Cyclic CRF agonists
US5663292A (en)	1994-12-12	1997-09-02	The Salk Institute For Biological Studies	Cyclic CRF analogs
US5660824A (en)	1995-05-24	1997-08-26	Grabstein; Kenneth H.	Muscle trophic factor
JP2002504802A (ja)	1995-06-13	2002-02-12	ザソルクインスティテュートフォアバイオロジカルスタディース	ウロコルチンペプチド
US5869450A (en)	1996-03-06	1999-02-09	The Regents Of The University Of California	Anti-inflammatory compositions and method with corticotropin-releasing factor analogs
JP4873825B2 (ja)	2000-08-04	2012-02-08	リサーチディベロップメントファンデーション	ウロコルチン蛋白質及びその利用
US20020082409A1 (en)	2000-10-26	2002-06-27	Hsu Sheau Yu	Stresscopins and their uses
US6670140B2 (en) *	2001-03-06	2003-12-30	The Procter & Gamble Company	Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors
US7192923B2 (en) *	2002-01-16	2007-03-20	The Procter & Gamble Company	Corticotropin releasing factor 2 receptor agonists

2002
- 2002-12-11 US US10/315,964 patent/US7192923B2/en not_active Expired - Fee Related
- 2002-12-11 US US10/317,252 patent/US6936585B2/en not_active Expired - Lifetime
- 2002-12-11 US US10/317,251 patent/US7192924B2/en not_active Expired - Fee Related
2003
- 2003-01-10 TW TW092100535A patent/TW200302278A/zh unknown
- 2003-01-10 TW TW092100533A patent/TWI300442B/zh not_active IP Right Cessation
- 2003-01-10 TW TW092100532A patent/TW200302276A/zh unknown
- 2003-01-14 PE PE2003000041A patent/PE20030849A1/es not_active Application Discontinuation
- 2003-01-14 PE PE2003000040A patent/PE20030974A1/es not_active Application Discontinuation
- 2003-01-14 PE PE2003000039A patent/PE20030747A1/es not_active Application Discontinuation
- 2003-01-15 AR ARP030100099A patent/AR038142A1/es unknown
- 2003-01-15 AR ARP030100101A patent/AR038144A1/es unknown
- 2003-01-15 MY MYPI20030136A patent/MY140306A/en unknown
- 2003-01-15 AR ARP030100100A patent/AR038143A1/es unknown
- 2003-01-16 BR BR0306838-2A patent/BR0306838A/pt not_active Application Discontinuation
- 2003-01-16 AT AT06117810T patent/ATE398632T1/de not_active IP Right Cessation
- 2003-01-16 WO PCT/US2003/001454 patent/WO2003062277A1/en active IP Right Grant
- 2003-01-16 AU AU2003205197A patent/AU2003205197B2/en not_active Ceased
- 2003-01-16 AT AT03703867T patent/ATE334147T1/de not_active IP Right Cessation
- 2003-01-16 DE DE60321730T patent/DE60321730D1/de not_active Expired - Lifetime
- 2003-01-16 KR KR1020047011052A patent/KR100758857B1/ko not_active IP Right Cessation
- 2003-01-16 RU RU2004124847/13A patent/RU2294333C2/ru active
- 2003-01-16 IL IL16243103A patent/IL162431A0/xx unknown
- 2003-01-16 AT AT03731963T patent/ATE383372T1/de not_active IP Right Cessation
- 2003-01-16 CA CA2470731A patent/CA2470731C/en not_active Expired - Fee Related
- 2003-01-16 JP JP2003562154A patent/JP4489434B2/ja not_active Expired - Fee Related
- 2003-01-16 ES ES03731965T patent/ES2287484T3/es not_active Expired - Lifetime
- 2003-01-16 MX MXPA04006885A patent/MXPA04006885A/es active IP Right Grant
- 2003-01-16 MX MXPA04006884A patent/MXPA04006884A/es active IP Right Grant
- 2003-01-16 AT AT03731965T patent/ATE362488T1/de not_active IP Right Cessation
- 2003-01-16 CN CNB038023644A patent/CN100391972C/zh not_active Expired - Fee Related
- 2003-01-16 PT PT03703867T patent/PT1465921E/pt unknown
- 2003-01-16 EP EP03731965A patent/EP1465923B1/de not_active Expired - Lifetime
- 2003-01-16 JP JP2003562145A patent/JP4508648B2/ja not_active Expired - Fee Related
- 2003-01-16 DK DK03703867T patent/DK1465921T3/da active
- 2003-01-16 ES ES03703867T patent/ES2269976T3/es not_active Expired - Lifetime
- 2003-01-16 EP EP06117810A patent/EP1724283B1/de not_active Expired - Lifetime
- 2003-01-16 WO PCT/US2003/001461 patent/WO2003062269A2/en active IP Right Grant
- 2003-01-16 NZ NZ533599A patent/NZ533599A/en unknown
- 2003-01-16 PT PT03731965T patent/PT1465923E/pt unknown
- 2003-01-16 PL PL03373139A patent/PL373139A1/xx not_active Application Discontinuation
- 2003-01-16 PL PL03373529A patent/PL373529A1/xx not_active Application Discontinuation
- 2003-01-16 EP EP03703867A patent/EP1465921B1/de not_active Expired - Lifetime
- 2003-01-16 DE DE60313845T patent/DE60313845T2/de not_active Expired - Lifetime
- 2003-01-16 IL IL15252903A patent/IL162529A0/xx unknown
- 2003-01-16 DE DE60318547T patent/DE60318547T2/de not_active Expired - Lifetime
- 2003-01-16 ES ES06117810T patent/ES2309909T3/es not_active Expired - Lifetime
- 2003-01-16 IL IL16253003A patent/IL162530A0/xx unknown
- 2003-01-16 WO PCT/US2003/001451 patent/WO2003062268A2/en active IP Right Grant
- 2003-01-16 JP JP2003562146A patent/JP4508649B2/ja not_active Expired - Fee Related
- 2003-01-16 MX MXPA04006883A patent/MXPA04006883A/es active IP Right Grant
- 2003-01-16 DK DK03731965T patent/DK1465923T3/da active
- 2003-01-16 NZ NZ533600A patent/NZ533600A/en unknown
- 2003-01-16 ES ES03731963T patent/ES2299701T3/es not_active Expired - Lifetime
- 2003-01-16 SI SI200330360T patent/SI1465921T1/sl unknown
- 2003-01-16 CA CA2470743A patent/CA2470743C/en not_active Expired - Fee Related
- 2003-01-16 CA CA2470656A patent/CA2470656C/en not_active Expired - Fee Related
- 2003-01-16 AU AU2003237419A patent/AU2003237419B2/en not_active Ceased
- 2003-01-16 KR KR1020047011051A patent/KR100735586B1/ko not_active IP Right Cessation
- 2003-01-16 KR KR1020047011057A patent/KR100758858B1/ko not_active IP Right Cessation
- 2003-01-16 DE DE60307044T patent/DE60307044T2/de not_active Expired - Lifetime
- 2003-01-16 CN CNA038023709A patent/CN1617887A/zh active Pending
- 2003-01-16 CN CNB038023520A patent/CN100475844C/zh not_active Expired - Fee Related
- 2003-01-16 EP EP03731963A patent/EP1465922B1/de not_active Expired - Lifetime
- 2003-01-16 PL PL03371364A patent/PL371364A1/xx unknown
- 2003-01-16 NZ NZ533598A patent/NZ533598A/en unknown
- 2003-01-16 BR BR0306826-9A patent/BR0306826A/pt not_active IP Right Cessation
- 2003-01-16 BR BR0306878-1A patent/BR0306878A/pt not_active IP Right Cessation
- 2003-03-01 SA SA03230564D patent/SA03230564A/ar unknown
- 2003-03-01 SA SA3230564A patent/SA03230564B1/ar unknown
- 2003-03-01 SA SA3230565A patent/SA03230565B1/ar unknown
2004
- 2004-06-24 ZA ZA2004/04995A patent/ZA200404995B/en unknown
- 2004-07-13 MA MA27778A patent/MA27590A1/fr unknown
- 2004-07-13 MA MA27779A patent/MA27591A1/fr unknown
- 2004-07-13 MA MA27780A patent/MA27592A1/fr unknown
- 2004-08-13 NO NO20043371A patent/NO20043371L/no not_active Application Discontinuation
- 2004-08-13 NO NO20043366A patent/NO20043366L/no not_active Application Discontinuation
- 2004-08-16 NO NO20043396A patent/NO20043396L/no not_active Application Discontinuation
2005
- 2005-05-04 US US11/121,612 patent/US7462597B2/en not_active Expired - Fee Related
- 2005-11-11 HK HK05110114A patent/HK1078095A1/xx not_active IP Right Cessation
2006
- 2006-07-28 CY CY20061101051T patent/CY1106133T1/el unknown
2007
- 2007-02-02 US US11/701,576 patent/US7608701B2/en not_active Expired - Fee Related
- 2007-02-02 US US11/701,912 patent/US7632933B2/en not_active Expired - Fee Related
2009
- 2009-01-07 IL IL196384A patent/IL196384A0/en unknown
- 2009-03-24 IL IL197774A patent/IL197774A0/en unknown
- 2009-10-26 US US12/605,718 patent/US7897731B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AR038143A1 (es)	2004-12-29
CN100475844C (zh)	2009-04-08
BR0306826A (pt)	2005-09-06
IL162431A0 (en)	2005-11-20
NO20043396L (no)	2004-10-06
US20030148956A1 (en)	2003-08-07
DE60321730D1 (de)	2008-07-31
MY140306A (en)	2009-12-31
RU2004124847A (ru)	2005-04-20
NZ533598A (en)	2007-03-30
DE60307044D1 (de)	2006-09-07
MXPA04006883A (es)	2004-12-06
CN1617886A (zh)	2005-05-18
EP1465921B1 (de)	2006-07-26
CA2470656C (en)	2011-06-28
US7462597B2 (en)	2008-12-09
ZA200404995B (en)	2005-06-29
TW200302278A (en)	2003-08-01
ATE383372T1 (de)	2008-01-15
IL196384A0 (en)	2011-07-31
US20100197579A1 (en)	2010-08-05
SA03230564B1 (ar)	2006-10-31
CA2470731C (en)	2011-06-21
MA27592A1 (fr)	2005-11-01
DE60313845T2 (de)	2008-01-31
US7192924B2 (en)	2007-03-20
PE20030974A1 (es)	2003-12-26
PT1465921E (pt)	2006-12-29
KR100758857B1 (ko)	2007-09-14
TW200302277A (en)	2003-08-01
US20030148957A1 (en)	2003-08-07
EP1724283A2 (de)	2006-11-22
IL197774A0 (en)	2009-12-24
JP2005521387A (ja)	2005-07-21
SI1465921T1 (sl)	2006-10-31
US7897731B2 (en)	2011-03-01
CY1106133T1 (el)	2011-06-08
BR0306878A (pt)	2004-10-26
JP4489434B2 (ja)	2010-06-23
KR100758858B1 (ko)	2007-09-14
NZ533600A (en)	2007-02-23
MXPA04006884A (es)	2004-12-06
CA2470656A1 (en)	2003-07-31
ES2269976T3 (es)	2007-04-01
RU2294333C2 (ru)	2007-02-27
TWI300442B (en)	2008-09-01
PL373529A1 (en)	2005-09-05
AR038144A1 (es)	2004-12-29
DK1465921T3 (da)	2006-11-27
SA03230564A (ar)	2005-12-03
US7608701B2 (en)	2009-10-27
DE60318547T2 (de)	2008-12-24
EP1724283B1 (de)	2008-06-18
US20090124793A1 (en)	2009-05-14
AU2003205197B2 (en)	2006-03-02
EP1724283A3 (de)	2007-04-11
SA03230565B1 (ar)	2006-10-31
CN1617887A (zh)	2005-05-18
PL371364A1 (en)	2005-06-13
IL162529A0 (en)	2005-11-20
US20030148958A1 (en)	2003-08-07
WO2003062268A2 (en)	2003-07-31
DE60318547D1 (de)	2008-02-21
US6936585B2 (en)	2005-08-30
DE60313845D1 (de)	2007-06-28
EP1465921A2 (de)	2004-10-13
JP2005522191A (ja)	2005-07-28
TW200302276A (en)	2003-08-01
MA27591A1 (fr)	2005-11-01
JP4508649B2 (ja)	2010-07-21
EP1465922B1 (de)	2008-01-09
US7192923B2 (en)	2007-03-20
MXPA04006885A (es)	2004-12-06
PL373139A1 (en)	2005-08-22
PE20030849A1 (es)	2003-12-01
US20060025339A1 (en)	2006-02-02
ES2287484T3 (es)	2007-12-16
KR20040082390A (ko)	2004-09-24
BR0306838A (pt)	2005-04-05
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US20080004435A1 (en)	2008-01-03
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WO2003062269A2 (en)	2003-07-31
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