DE60321318D1 - Gewinnung von delta-9 tetrahydrocannabinol - Google Patents

Gewinnung von delta-9 tetrahydrocannabinol

Info

Publication number
DE60321318D1
DE60321318D1 DE60321318T DE60321318T DE60321318D1 DE 60321318 D1 DE60321318 D1 DE 60321318D1 DE 60321318 T DE60321318 T DE 60321318T DE 60321318 T DE60321318 T DE 60321318T DE 60321318 D1 DE60321318 D1 DE 60321318D1
Authority
DE
Germany
Prior art keywords
acid
tetrahydrocannabinol
gaining
delta
thc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60321318T
Other languages
English (en)
Inventor
Neil John Goodwin
Nicolas James Archer
Christopher Murray
Alan Kenneth Greenwood
Derek Mchattie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Resolution Chemicals Ltd
Original Assignee
Resolution Chemicals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0202396A external-priority patent/GB0202396D0/en
Application filed by Resolution Chemicals Ltd filed Critical Resolution Chemicals Ltd
Application granted granted Critical
Publication of DE60321318D1 publication Critical patent/DE60321318D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Optical Integrated Circuits (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Pyrane Compounds (AREA)
  • Extraction Or Liquid Replacement (AREA)
DE60321318T 2002-02-01 2003-02-03 Gewinnung von delta-9 tetrahydrocannabinol Expired - Lifetime DE60321318D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0202396A GB0202396D0 (en) 2002-02-01 2002-02-01 Production of delta 9 tetrahydrocannabinol
GB0214022A GB0214022D0 (en) 2002-02-01 2002-06-18 Production of delta 9 tetrahydrocannabinol
PCT/GB2003/000441 WO2003064407A2 (en) 2002-02-01 2003-02-03 Production of δ9 tetrahydrocannabinol

Publications (1)

Publication Number Publication Date
DE60321318D1 true DE60321318D1 (de) 2008-07-10

Family

ID=27665366

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60332776T Expired - Lifetime DE60332776D1 (de) 2002-02-01 2003-02-03 Herstellung von Delta-9-Tetrahydrocannabinol
DE60321318T Expired - Lifetime DE60321318D1 (de) 2002-02-01 2003-02-03 Gewinnung von delta-9 tetrahydrocannabinol

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60332776T Expired - Lifetime DE60332776D1 (de) 2002-02-01 2003-02-03 Herstellung von Delta-9-Tetrahydrocannabinol

Country Status (17)

Country Link
US (3) US7524881B2 (de)
EP (2) EP1474412B1 (de)
JP (1) JP2005526715A (de)
CN (2) CN1642934A (de)
AT (1) ATE396984T1 (de)
AU (2) AU2003205844B2 (de)
BR (1) BR0307330A (de)
CA (1) CA2474951A1 (de)
DE (2) DE60332776D1 (de)
DK (1) DK1474412T3 (de)
ES (1) ES2305437T3 (de)
NO (1) NO20043209L (de)
NZ (2) NZ552547A (de)
PT (1) PT1474412E (de)
SI (1) SI1474412T1 (de)
WO (1) WO2003064407A2 (de)
ZA (1) ZA200405938B (de)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60332776D1 (de) * 2002-02-01 2010-07-08 Resolution Chemicals Ltd Herstellung von Delta-9-Tetrahydrocannabinol
GB2391865B (en) * 2002-08-14 2005-06-01 Gw Pharma Ltd Improvements in the extraction of pharmaceutically active components from plant materials
EP1536810B1 (de) * 2002-08-14 2012-08-01 GW Pharma Limited Extraktion von pharmazeutisch aktiven cannabinoiden aus pflanzlichem material
GB0222077D0 (en) 2002-09-23 2002-10-30 Gw Pharma Ltd Methods of preparing cannabinoids from plant material
GB2408978B (en) * 2002-09-23 2006-04-05 Gw Pharma Ltd Methods of preparing delta-9 tetrahydrocannabinol from plant material
TWI436991B (zh) 2004-11-22 2014-05-11 Euro Celtique Sa 用於純化反-(-)-△9-四氫***酚與反-(+)-△9-四氫***酚之方法
WO2006063109A2 (en) * 2004-12-09 2006-06-15 Insys Therapeutics, Inc. Room-temperature stable dronabinol formulations
TWI366460B (en) * 2005-06-16 2012-06-21 Euro Celtique Sa Cannabinoid active pharmaceutical ingredient for improved dosage forms
KR20080063800A (ko) * 2005-09-29 2008-07-07 에이엠알 테크놀로지, 인크. 델타-9-테트라히드로칸나비놀의 제조 방법
CA2659775A1 (en) * 2006-08-04 2008-02-14 Insys Therapeutics Inc. Aqueous dronabinol formulations
US20080103193A1 (en) * 2006-10-26 2008-05-01 Trevor Percival Castor Methods for making compositions and compositions for treating pain and cachexia
GB0703284D0 (en) 2007-02-20 2007-03-28 Resolution Chemicals Ltd Delta 9 - tetrahydrocannabinol processing
US20090181080A1 (en) * 2007-08-06 2009-07-16 Insys Therapeutics Inc. Oral cannabinnoid liquid formulations and methods of treatment
US20090042974A1 (en) * 2007-08-07 2009-02-12 Anson David Parker Compositions And Methods Relating To Extensible Transgenic Vector Assembler, Pestilence Ridder, Plus Cannabinoid Producer
GB0807915D0 (en) * 2008-05-01 2008-06-04 Resolution Chemicals Ltd Production of delta 9 tetrahydrocannabinol
US8343553B2 (en) 2011-04-18 2013-01-01 Hospodor Andrew D Essential element extractor
EP2760444B1 (de) * 2011-09-29 2020-04-22 THC Pharm GmbH The Health Concept Cannabinoidcarbonsäuren, salze von cannabinoidcarbonsäuren, deren herstellung und anwendungen
US9358259B2 (en) 2012-03-20 2016-06-07 Andrew David Hospodor Recycling cannabinoid extractor
SI2844243T1 (sl) * 2012-05-03 2020-02-28 Echo Pharmaceuticals B.V. Metoda za pripravo izolata iz rastline konoplje, ki obsega delta-9-tetrahidrokanabinol
US20130337052A1 (en) * 2012-06-19 2013-12-19 Patricia Linert System and Method of Reducing Impairment of Alertness, Concentration, Motivation, and Creativity Caused by Medication
US9155767B2 (en) 2012-10-18 2015-10-13 Andrew D. Hospodor Essential element management
EP4137142A1 (de) 2013-03-14 2023-02-22 Purple Mundo, Inc. Bioaktive konzentrate und verwendungen davon
US9199960B2 (en) * 2013-05-02 2015-12-01 Frederick R. Ferri Method and apparatus for processing herbaceous plant materials including the cannabis plant
US9380813B2 (en) 2014-02-11 2016-07-05 Timothy McCullough Drug delivery system and method
US9220294B2 (en) 2014-02-11 2015-12-29 Timothy McCullough Methods and devices using cannabis vapors
US10821240B2 (en) 2014-02-11 2020-11-03 Vapor Cartridge Technology Llc Methods and drug delivery devices using cannabis
US20170312327A1 (en) * 2014-11-17 2017-11-02 Connoisseur Holdings, Llc Extraction devices, systems, and methods
US10207198B2 (en) * 2015-01-22 2019-02-19 Phytoplant Research S.L. Methods of purifying cannabinoids using liquid:liquid chromatography
US11034639B2 (en) 2015-01-22 2021-06-15 Phytoplant Research S.L. Methods of purifying cannabinoids using liquid:liquid chromatography
US9765000B2 (en) * 2015-01-22 2017-09-19 Phytoplant Research S.L. Methods of purifying cannabinoids, compositions and kits thereof
US11040295B2 (en) 2015-02-06 2021-06-22 Joseph Francis Payack Method and apparatus for extracting plant oils using ethanol water
WO2016179247A1 (en) 2015-05-07 2016-11-10 Axim Biotechnologies, Inc. Process to extract and purify delta-9-tetrahydrocannabinol
US10913071B2 (en) 2016-03-09 2021-02-09 Pearson Incorporated Scalper apparatus and processing system
US10499584B2 (en) 2016-05-27 2019-12-10 New West Genetics Industrial hemp Cannabis cultivars and seeds with stable cannabinoid profiles
AU2017290107A1 (en) 2016-06-29 2019-01-17 CannScience Innovations Inc. Decarboxylated cannabis resins, uses thereof and methods of making same
US10322487B1 (en) 2016-07-15 2019-06-18 Pearson Incorporated Roller mill grinding apparatus with regenerative capability
CN109803643A (zh) * 2016-07-15 2019-05-24 S.S.斯坦纳公司 ***生物质和***提取物中***二酚酸的脱羧
US10239808B1 (en) 2016-12-07 2019-03-26 Canopy Holdings, LLC Cannabis extracts
US10702495B2 (en) 2017-02-20 2020-07-07 Nexien Biopharma, Inc. Method and compositions for treating dystrophies and myotonia
IT201700085508A1 (it) * 2017-07-26 2019-01-26 Inalco S R L Metodo per la produzione di cannabinoidi da varietà di canapa industriale
US10807098B1 (en) 2017-07-26 2020-10-20 Pearson Incorporated Systems and methods for step grinding
US10272360B2 (en) 2017-08-05 2019-04-30 Priya Naturals, Inc. Phytochemical extraction system and methods to extract phytochemicals from plants including plants of the family Cannabaceae sensu stricto
US10406453B2 (en) * 2017-09-29 2019-09-10 NextLeaf Solutions Ltd. Cannabinoid extraction process using brine
US10941102B2 (en) * 2017-11-29 2021-03-09 Robert Henry Wohleb Aqueous leaching method to produce microcrystalline powder
CN111788171A (zh) * 2018-01-29 2020-10-16 菲拓普兰特研究公司 使用液:液色谱法纯化***素的方法
EP3745884A1 (de) 2018-01-31 2020-12-09 Canopy Holdings, Llc Hanfpulver
US11325133B1 (en) 2018-07-26 2022-05-10 Pearson Incorporated Systems and methods for monitoring the roll diameter and shock loads in a milling apparatus
WO2020060959A1 (en) * 2018-09-17 2020-03-26 Sorbent Technologies, Inc. Methods for removing contaminants from plant-derived pharmaceuticals
US11040932B2 (en) 2018-10-10 2021-06-22 Treehouse Biotech, Inc. Synthesis of cannabigerol
US10751722B1 (en) 2018-10-24 2020-08-25 Pearson Incorporated System for processing cannabis crop materials
EP3911148A4 (de) * 2019-01-17 2022-10-12 Synthonics, Inc. Feste mizellare zusammensetzungen von cannabinoidsäuren
US10785906B2 (en) 2019-02-19 2020-09-29 Pearson Incorporated Plant processing system
KR20220007855A (ko) * 2019-03-24 2022-01-19 오메가 라이프 사이언스 리미티드 전자 담배
US20200323791A1 (en) 2019-04-11 2020-10-15 Mantrose-Haueser Co., Inc. Cannabis delivery with protective glaze coating
AU2020262269B2 (en) 2019-04-23 2024-03-28 Soma Oil Llc Cannabis processing systems and methods
EP3750528A1 (de) 2019-06-11 2020-12-16 Nexien Biopharma, Inc. Zusammensetzungen zur behandlung von dystrophien und myotonie
US11497249B2 (en) 2019-09-16 2022-11-15 Vapor Cartridge Technology Llc Drug delivery system with stackable substrates
US10757860B1 (en) 2019-10-31 2020-09-01 Hemp Processing Solutions, LLC Stripper apparatus crop harvesting system
US10933424B1 (en) 2019-12-11 2021-03-02 Pearson Incorporated Grinding roll improvements
CN111039760A (zh) * 2019-12-16 2020-04-21 福建省中科生物股份有限公司 一种制备酚类化合物的方法
US11351476B2 (en) * 2020-01-07 2022-06-07 Agrify Corporation Method for chemical separation of cannabinoids
US20230271930A1 (en) * 2020-06-09 2023-08-31 Protonify Corporation Process for isolation and purification of thca from cannabis
CN116847913A (zh) 2020-09-04 2023-10-03 赫博利生物科技股份公司 不含thc的***素浓缩物、其获得方法及其用途
US11242328B1 (en) * 2021-02-25 2022-02-08 Acid Neutral Alkaline Laboratory Heterogeneous catalyst and method for preparation of aromatic tricyclic pyrans
US11352337B1 (en) * 2021-06-02 2022-06-07 Acid Neutral Alkaline Laboratory Zeolite catalyst and method for preparation of aromatic tricyclic pyrans
CN115260005B (zh) * 2022-08-30 2024-01-30 晨光生物科技集团股份有限公司 一种纯化提取***二酚的方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342971A (en) * 1992-12-29 1994-08-30 The Australian National University Process for the preparation of dibenzo[b,d]pyrans
EP0824320A4 (de) 1995-05-05 2000-06-07 Hauser Inc Carnosinsäure hoher reinheit aus rosmarin-und salbeiextrakten durch ph-gesteuerte fällung
GB9726916D0 (en) * 1997-12-19 1998-02-18 Danbiosyst Uk Nasal formulation
US20020039795A1 (en) 1998-10-26 2002-04-04 Elsohly Et Al Method of preparing delta-9-tetrahydrocannabinol
US6730519B2 (en) * 1998-10-26 2004-05-04 The University Of Mississippi Method of preparing delta-9-tetrahydrocannabinol
DE60332776D1 (de) * 2002-02-01 2010-07-08 Resolution Chemicals Ltd Herstellung von Delta-9-Tetrahydrocannabinol

Also Published As

Publication number Publication date
DK1474412T3 (da) 2008-09-01
CN1642934A (zh) 2005-07-20
EP1803717B1 (de) 2010-05-26
NZ552547A (en) 2008-03-28
ZA200405938B (de) 2006-05-31
US7592468B2 (en) 2009-09-22
WO2003064407A3 (en) 2003-10-16
US20090253783A1 (en) 2009-10-08
JP2005526715A (ja) 2005-09-08
CA2474951A1 (en) 2003-08-07
NZ534430A (en) 2007-09-28
CN100999513A (zh) 2007-07-18
EP1803717A3 (de) 2007-07-11
NO20043209L (no) 2004-10-28
ATE396984T1 (de) 2008-06-15
WO2003064407A2 (en) 2003-08-07
DE60332776D1 (de) 2010-07-08
US7524881B2 (en) 2009-04-28
PT1474412E (pt) 2008-07-04
AU2006252300B2 (en) 2009-02-12
BR0307330A (pt) 2004-12-07
EP1803717A2 (de) 2007-07-04
SI1474412T1 (sl) 2008-10-31
AU2006252300A1 (en) 2007-01-25
AU2003205844B2 (en) 2006-10-12
US20050171361A1 (en) 2005-08-04
EP1474412A2 (de) 2004-11-10
US20050049298A1 (en) 2005-03-03
ES2305437T3 (es) 2008-11-01
EP1474412B1 (de) 2008-05-28

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