DE60308435D1 - Verfahren zur Umwandlung von Dihidroisoxazol Derivate in Gamma-Hydroxaminsäurederivate, z.B Monatins - Google Patents
Verfahren zur Umwandlung von Dihidroisoxazol Derivate in Gamma-Hydroxaminsäurederivate, z.B MonatinsInfo
- Publication number
- DE60308435D1 DE60308435D1 DE60308435T DE60308435T DE60308435D1 DE 60308435 D1 DE60308435 D1 DE 60308435D1 DE 60308435 T DE60308435 T DE 60308435T DE 60308435 T DE60308435 T DE 60308435T DE 60308435 D1 DE60308435 D1 DE 60308435D1
- Authority
- DE
- Germany
- Prior art keywords
- derivatives
- gamma
- dihidroisoxazole
- monatin
- conversion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Health & Medical Sciences (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Indole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002098515 | 2002-04-01 | ||
JP2002098515A JP2003292484A (ja) | 2002-04-01 | 2002-04-01 | γ−ヒドロキシアミノ酸誘導体及びモナティン類の製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60308435D1 true DE60308435D1 (de) | 2006-11-02 |
DE60308435T2 DE60308435T2 (de) | 2007-05-03 |
Family
ID=28035889
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60308435T Expired - Lifetime DE60308435T2 (de) | 2002-04-01 | 2003-03-10 | Verfahren zur Umwandlung von Dihidroisoxazol Derivate in Gamma-Hydroxaminsäurederivate, z.B Monatins |
Country Status (6)
Country | Link |
---|---|
US (1) | US7329427B2 (de) |
EP (1) | EP1350791B1 (de) |
JP (1) | JP2003292484A (de) |
AT (1) | ATE340174T1 (de) |
CA (1) | CA2423691C (de) |
DE (1) | DE60308435T2 (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4991091B2 (ja) * | 2001-11-30 | 2012-08-01 | 味の素株式会社 | モナティンの非天然型立体異性体塩の結晶及びその使用 |
US7297800B2 (en) | 2001-12-27 | 2007-11-20 | Ajinomoto Co., Inc. | Process of producing glutamate derivatives |
JP4196832B2 (ja) * | 2001-12-27 | 2008-12-17 | 味の素株式会社 | グルタミン酸化合物及びそれらの製造中間体の製造方法並びにそのための新規中間体 |
JP2003292484A (ja) | 2002-04-01 | 2003-10-15 | Ajinomoto Co Inc | γ−ヒドロキシアミノ酸誘導体及びモナティン類の製造方法 |
US8372989B2 (en) | 2002-04-23 | 2013-02-12 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin and its precursors |
US7572607B2 (en) | 2002-04-23 | 2009-08-11 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of monatin and its precursors |
ATE463568T1 (de) | 2002-08-26 | 2010-04-15 | Ajinomoto Kk | Neue aldolasen und verfahren zur herstellung von substituierter alpha-ketosäure |
JP4544154B2 (ja) * | 2002-12-09 | 2010-09-15 | 味の素株式会社 | 変異型d−アミノトランスフェラーゼおよびこれを用いた光学活性グルタミン酸誘導体の製造方法 |
JP4770174B2 (ja) * | 2003-01-09 | 2011-09-14 | 味の素株式会社 | グルタミン酸誘導体及びピログルタミン酸誘導体の製造方法並びに新規製造中間体 |
WO2005014839A2 (en) * | 2003-08-01 | 2005-02-17 | Cargill, Incorporated | Monatin tabletop sweetener compositions and methods of making same |
ATE360370T1 (de) * | 2003-08-14 | 2007-05-15 | Cargill Inc | Monatinhaltige kaugummizusammensetzungen und verfahren zu ihrer herstellung |
US20050106305A1 (en) * | 2003-08-25 | 2005-05-19 | Cargill, Inc. | Beverage compositions comprising monatin and methods of making same |
EP1678313B1 (de) | 2003-10-21 | 2011-02-16 | Cargill, Incorporated | Herstellung von monatin und monatinvorstufen |
JP5113978B2 (ja) * | 2003-11-21 | 2013-01-09 | 味の素株式会社 | グルタミン酸誘導体の有機アミン塩及びその利用 |
JP5319885B2 (ja) * | 2004-02-27 | 2013-10-16 | 味の素株式会社 | モナティンの製造方法 |
US7935377B2 (en) * | 2004-06-04 | 2011-05-03 | Ajinomoto Co., Inc. | Crystals of free (2R, 4R)-monatin and use thereof |
CA2506247C (en) * | 2004-06-07 | 2012-02-21 | Ajinomoto Co., Inc. | Novel aldolase, and method for producing optically active ihog and monatin |
RU2007116971A (ru) * | 2004-10-05 | 2008-11-27 | Адзиномото Ко., Инк. (Jp) | Способ получения производного аминокислоты из гидроксииминокислоты |
CA2583434A1 (en) * | 2004-10-15 | 2006-04-20 | Ajinomoto Co., Inc. | Sweetener composition comprising monatin or a salt thereof and method for preserving monatin |
WO2006113897A2 (en) | 2005-04-20 | 2006-10-26 | Cargill, Incorporated | Products and methods for in vivo secretion of monatin |
US8158389B2 (en) | 2005-04-20 | 2012-04-17 | Cargill, Incorporated | Products and methods for in vivo secretion of monatin |
US8076108B2 (en) | 2005-04-26 | 2011-12-13 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
US7582455B2 (en) | 2005-04-26 | 2009-09-01 | Cargill, Incorporated | Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors |
EP2361976B1 (de) * | 2005-04-26 | 2016-05-25 | Cargill, Incorporated | Polypeptide und Biosynthesewege zur Herstellung von Stereoisomeren von Monatin und ihren Vorläufern |
US9101160B2 (en) | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
MX2008011477A (es) | 2006-03-07 | 2008-09-23 | Cargill Inc | Aldolasas, acidos nucleicos que las codifican y metodos para hacerlas y usarlas. |
JP2009538145A (ja) | 2006-05-24 | 2009-11-05 | カーギル・インコーポレイテッド | 平衡反応の収量を増加させるための方法およびシステム |
US20090198072A1 (en) * | 2006-05-24 | 2009-08-06 | Cargill, Incorporated | Methods and systems for increasing production of equilibrium reactions |
US8017168B2 (en) | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
US8076107B2 (en) * | 2007-10-01 | 2011-12-13 | Cargill, Incorporated | Production of monatin stereoisomers |
US8003361B2 (en) | 2007-10-01 | 2011-08-23 | Cargill Incorporated | Production of monatin enantiomers |
US8367847B2 (en) | 2007-10-01 | 2013-02-05 | Cargill, Incorporated | Production of monatin enantiomers |
EP2107053A1 (de) * | 2008-03-11 | 2009-10-07 | Ajinomoto Co., Inc. | Hydratkristalle von (2R,4R)-Monatin Mononatrium-Salz |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2240105B (en) * | 1990-01-19 | 1993-06-09 | Technology Finance Corp | Process for the production of 3-(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl) indole |
US5994559A (en) * | 1998-08-06 | 1999-11-30 | The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations | Synthesis of monatin-A high intensity natural sweetener |
JP2002060382A (ja) * | 2000-08-22 | 2002-02-26 | Ajinomoto Co Inc | モナティンの立体異性体及びその使用、並びにモナティン類の製造方法及びそのための中間体 |
JP2003292484A (ja) | 2002-04-01 | 2003-10-15 | Ajinomoto Co Inc | γ−ヒドロキシアミノ酸誘導体及びモナティン類の製造方法 |
-
2002
- 2002-04-01 JP JP2002098515A patent/JP2003292484A/ja active Pending
-
2003
- 2003-03-10 EP EP03005268A patent/EP1350791B1/de not_active Expired - Lifetime
- 2003-03-10 DE DE60308435T patent/DE60308435T2/de not_active Expired - Lifetime
- 2003-03-10 AT AT03005268T patent/ATE340174T1/de not_active IP Right Cessation
- 2003-03-27 CA CA2423691A patent/CA2423691C/en not_active Expired - Fee Related
- 2003-03-27 US US10/397,407 patent/US7329427B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2423691C (en) | 2010-09-14 |
CA2423691A1 (en) | 2003-10-01 |
US7329427B2 (en) | 2008-02-12 |
DE60308435T2 (de) | 2007-05-03 |
JP2003292484A (ja) | 2003-10-15 |
EP1350791B1 (de) | 2006-09-20 |
US20030228403A1 (en) | 2003-12-11 |
ATE340174T1 (de) | 2006-10-15 |
EP1350791A1 (de) | 2003-10-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |