DE60233436D1 - In der mundhöhle dispergierbare feste pharmazeutische form - Google Patents

In der mundhöhle dispergierbare feste pharmazeutische form

Info

Publication number
DE60233436D1
DE60233436D1 DE60233436T DE60233436T DE60233436D1 DE 60233436 D1 DE60233436 D1 DE 60233436D1 DE 60233436 T DE60233436 T DE 60233436T DE 60233436 T DE60233436 T DE 60233436T DE 60233436 D1 DE60233436 D1 DE 60233436D1
Authority
DE
Germany
Prior art keywords
mouthhouse
solid pharmaceutical
pharmaceutical form
dispersible solid
dispersible
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60233436T
Other languages
English (en)
Inventor
Michel Serpelloni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roquette Freres SA
Original Assignee
Roquette Freres SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roquette Freres SA filed Critical Roquette Freres SA
Application granted granted Critical
Publication of DE60233436D1 publication Critical patent/DE60233436D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60233436T 2002-01-18 2002-12-19 In der mundhöhle dispergierbare feste pharmazeutische form Expired - Lifetime DE60233436D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0200647A FR2834889B1 (fr) 2002-01-18 2002-01-18 Forme pharmaceutique solide orodispersible
PCT/FR2002/004454 WO2003061623A1 (fr) 2002-01-18 2002-12-19 Forme pharmaceutique solide orodispersible

Publications (1)

Publication Number Publication Date
DE60233436D1 true DE60233436D1 (de) 2009-10-01

Family

ID=27589521

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60233436T Expired - Lifetime DE60233436D1 (de) 2002-01-18 2002-12-19 In der mundhöhle dispergierbare feste pharmazeutische form

Country Status (22)

Country Link
US (1) US7201922B2 (de)
EP (1) EP1465593B1 (de)
JP (1) JP2005515240A (de)
KR (1) KR100961367B1 (de)
CN (1) CN1248681C (de)
AT (1) ATE439828T1 (de)
AU (1) AU2002364468C1 (de)
BR (1) BR0208161A (de)
CA (1) CA2441796A1 (de)
CZ (1) CZ20032486A3 (de)
DE (1) DE60233436D1 (de)
FR (1) FR2834889B1 (de)
HU (1) HUP0303948A2 (de)
IL (2) IL158691A0 (de)
MX (1) MXPA03008420A (de)
NO (1) NO326259B1 (de)
NZ (1) NZ529694A (de)
PL (1) PL209144B1 (de)
RU (1) RU2317812C2 (de)
SK (1) SK287812B6 (de)
WO (1) WO2003061623A1 (de)
ZA (1) ZA200308664B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7815937B2 (en) * 1998-10-27 2010-10-19 Biovail Laboratories International Srl Quick dissolve compositions and tablets based thereon
CA2348452A1 (en) * 1998-10-27 2000-05-04 Biovail Technologies Ltd. Microparticles containing peg and/or peg glyceryl esters
FR2834894B1 (fr) * 2002-01-21 2004-02-27 Servier Lab Composition pharmaceutique orodispersible de piribedil
FR2834893B1 (fr) * 2002-01-23 2004-02-27 Servier Lab Composition pharmaceutique orodispersible de perindopril
FR2834890B1 (fr) * 2002-01-23 2004-02-27 Servier Lab Composition pharmaceutique orodispersible d'agomelatine
FR2834896B1 (fr) * 2002-01-23 2004-02-27 Servier Lab Composition pharmaceutique orodispersible d'ivabradine
DE10229472A1 (de) * 2002-07-01 2004-01-15 Symrise Gmbh & Co. Kg Kompaktierter Milchsäurementhylester
FR2857263B1 (fr) * 2003-07-09 2005-09-09 Sanofi Synthelabo Nouvelle composition pharmaceutique solide comprenant de l'amisulpride
FR2858556B1 (fr) * 2003-08-06 2006-03-10 Galenix Innovations Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparation
TWI358407B (en) * 2005-06-22 2012-02-21 Lundbeck & Co As H Crystalline base of escitalopram and orodispersibl
KR101109633B1 (ko) 2007-08-03 2012-01-31 제이더블유중외제약 주식회사 활성성분의 코팅막이 보호되는 구강내붕해제형을 제조하기위한 조성물
FR2920311B1 (fr) * 2007-08-31 2010-06-18 Galenix Innovations Composition solide, orodispersible et/ou dispersible, sans excipient a effet notoire et son procede de preparation
US20120040001A1 (en) * 2009-02-12 2012-02-16 Fuji Chemical Industry Co., Ltd. Disintegrating particle composition and rapidly disintegrating compression-molded material used the same
RU2497505C1 (ru) * 2012-11-07 2013-11-10 Максим Эдуардович Запольский Новая лекарственная композиция для лечения болевого синдрома при спазме гладкой мускулатуры
RU2503447C1 (ru) * 2012-11-20 2014-01-10 Максим Эдуардович Запольский Лекарственное средство в форме ородисперсной таблетки и способ получения лекарственного средства
JP5713421B1 (ja) * 2013-07-19 2015-05-07 株式会社三和化学研究所 口腔内崩壊錠
DE102017103346A1 (de) * 2017-02-17 2018-08-23 Lts Lohmann Therapie-Systeme Ag Strukturierte orodispergierbare Filme
WO2019146642A1 (ja) * 2018-01-24 2019-08-01 大原薬品工業株式会社 γ－アミノ酪酸誘導体含有錠剤の化学的安定性を改善する方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4327077A (en) * 1981-05-29 1982-04-27 Life Savers, Inc. Compressed chewable antacid tablet and method for forming same
US5464632C1 (en) 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
JP3349535B2 (ja) * 1993-01-12 2002-11-25 フロイント産業株式会社 球形顆粒の製造方法
US5895664A (en) * 1993-09-10 1999-04-20 Fuisz Technologies Ltd. Process for forming quickly dispersing comestible unit and product therefrom
IL112106A0 (en) * 1993-12-22 1995-03-15 Ergo Science Inc Accelerated release composition containing bromocriptine
DE69738829D1 (de) * 1996-07-12 2008-08-21 Daiichi Seiyaku Co Schnell zerfallende, druckgeformte Materialien sowie Prozess zu deren Herstellung
FR2752162B1 (fr) 1996-08-07 1998-11-06 Jouveinal Lab Comprime de maleate de trimebutine pellicule
FR2766089B1 (fr) 1997-07-21 2000-06-02 Prographarm Lab Comprime multiparticulaire perfectionne a delitement rapide
AU3574500A (en) 1999-03-25 2000-10-16 Yuhan Corporation Rapidly disintegrable tablet for oral administration
US6316029B1 (en) * 2000-05-18 2001-11-13 Flak Pharma International, Ltd. Rapidly disintegrating solid oral dosage form
EP1175899B1 (de) 2000-07-27 2007-08-29 Roquette FrÀ¨res Granulat bestehend aus Stärke und Laktose
CN1469737A (zh) * 2000-10-16 2004-01-21 ��һ��������ҩ��ʽ���� 口腔内快速崩解的药用组合物及其制备方法
FR2823668B1 (fr) * 2001-04-20 2004-02-27 Ethypharm Lab Prod Ethiques Comprimes effervescents orodispersibles
US6723348B2 (en) * 2001-11-16 2004-04-20 Ethypharm Orodispersible tablets containing fexofenadine
US7118765B2 (en) * 2001-12-17 2006-10-10 Spi Pharma, Inc. Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms
PL371259A1 (en) * 2001-12-21 2005-06-13 Pfizer Products Inc. Directly compressible formulations of azithromycin
FR2834890B1 (fr) * 2002-01-23 2004-02-27 Servier Lab Composition pharmaceutique orodispersible d'agomelatine
JP2005526095A (ja) * 2002-03-20 2005-09-02 エラン ファーマ インターナショナル，リミティド 脆砕性の低い急速溶解投与剤型

Also Published As

Publication number Publication date
JP2005515240A (ja) 2005-05-26
CZ20032486A3 (cs) 2004-01-14
AU2002364468C1 (en) 2009-01-22
EP1465593B1 (de) 2009-08-19
KR100961367B1 (ko) 2010-06-07
NO20034139D0 (no) 2003-09-17
NO20034139L (no) 2003-11-11
HU0303948D0 (en) 2004-01-28
CN1516576A (zh) 2004-07-28
US7201922B2 (en) 2007-04-10
US20030147947A1 (en) 2003-08-07
FR2834889A1 (fr) 2003-07-25
ATE439828T1 (de) 2009-09-15
NZ529694A (en) 2006-04-28
CN1248681C (zh) 2006-04-05
MXPA03008420A (es) 2004-03-16
NO326259B1 (no) 2008-10-27
RU2317812C2 (ru) 2008-02-27
SK11712003A3 (sk) 2004-02-03
PL209144B1 (pl) 2011-07-29
SK287812B6 (sk) 2011-10-04
FR2834889B1 (fr) 2004-04-02
AU2002364468B2 (en) 2008-06-26
PL362762A1 (en) 2004-11-02
HUP0303948A2 (hu) 2004-04-28
IL158691A (en) 2008-08-07
KR20040073288A (ko) 2004-08-19
EP1465593A1 (de) 2004-10-13
WO2003061623A1 (fr) 2003-07-31
RU2003128025A (ru) 2005-03-27
ZA200308664B (en) 2004-11-08
CA2441796A1 (fr) 2003-07-31
IL158691A0 (en) 2004-05-12
BR0208161A (pt) 2004-03-02

Similar Documents

Publication Publication Date Title
DE60233436D1 (de) In der mundhöhle dispergierbare feste pharmazeutische form
CY2014001I1 (el) Συνδυασμος αζελαστινης και φλουτικαζονης
NO20033556L (no) Farmasöytiske formuleringer
CY1110385T1 (el) Χρηση αναστολεων της il-18 για τη θεραπεια και/ή προληψη της αθηροσκληρωσης
DE60307677D1 (de) Dispergierbare pharmazeutische zusammensetzungen
DK1198233T3 (da) Sulfonamid- og sulfamidsubstituerede imidazoquinoliner
HRP20041152B1 (en) Pharmaceutical formulations
DK1501534T3 (da) Desmopressin i orodispergerbar dosisform
NO20033785L (no) Farmasöytisk formulering
DE60131760D1 (de) Vorrichtung zur verabreichung von physiologisch aktiven wirkstoffen in pulverform
DK1425019T3 (da) Farmaceutisk sammensætning omfattende et androgen
DE60210139D1 (de) Pharmazeutische zusammensetzungen enthaltend tegaserod
TW200602062A (en) Improved formulations of 6-mercaptopurine
NO20035627D0 (no) Farmasöytisk formulering
DE60329755D1 (de) Basische nichtpeptid-bradykinin-antagonisten und pharmazeutische zusammensetzungen daraus
DE60134575D1 (de) Kombination enthaltend einen at1-rezeptor antagonisten und einen insulinsekretion verstärker oder einen insulin sensibilisator
ATE405293T1 (de) Selbstemulgierende und selbstmicroemulgierende formulierungen zur oralen verabreichung von taxoiden
DK1474152T3 (da) Orodispergerbar farmaceutisk sammensætning omfattende ivabradin
DK1467750T3 (da) Orodispergerbar farmaceutisk sammensætning omfattende perindopril
EE05263B1 (et) IL-18 inhibiitorite kasutamine keskn„rvissteemi kahjustuste raviks v?i ennetamiseks
FR2834894B1 (fr) Composition pharmaceutique orodispersible de piribedil
DE60228736D1 (de) Menschliches bmcc1-gen
ITRM20030219A0 (it) Uso della liquerizia per la prevenzione e la cura di aids e sars.
NO20041236L (no) Farmasoytisk formulering
ITRM20030436A1 (it) Procedimento e dispositivo per la creazione di vuoti

Legal Events

Date Code Title Description
8364 No opposition during term of opposition