DE602005019167D1 - Angiopoietin-like 4 protein hemmer kombinationen und deren verwendung - Google Patents

Angiopoietin-like 4 protein hemmer kombinationen und deren verwendung

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Publication number
DE602005019167D1
DE602005019167D1 DE602005019167T DE602005019167T DE602005019167D1 DE 602005019167 D1 DE602005019167 D1 DE 602005019167D1 DE 602005019167 T DE602005019167 T DE 602005019167T DE 602005019167 T DE602005019167 T DE 602005019167T DE 602005019167 D1 DE602005019167 D1 DE 602005019167D1
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Germany
Prior art keywords
angiopoietin
protein
combinations
hemmer
cancer
Prior art date
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Active
Application number
DE602005019167T
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English (en)
Inventor
Napoleone Ferrara
Hans-Peter Gerber
Xiao Huan Liang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
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Genentech Inc
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Application filed by Genentech Inc filed Critical Genentech Inc
Publication of DE602005019167D1 publication Critical patent/DE602005019167D1/de
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Anticipated expiration legal-status Critical

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
DE602005019167T 2004-07-20 2005-07-19 Angiopoietin-like 4 protein hemmer kombinationen und deren verwendung Active DE602005019167D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58978204P 2004-07-20 2004-07-20
PCT/US2005/025734 WO2006014729A2 (en) 2004-07-20 2005-07-19 Inhibitors of angiopoietin-like 4 protein, combinations, and their use

Publications (1)

Publication Number Publication Date
DE602005019167D1 true DE602005019167D1 (de) 2010-03-18

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ID=35787710

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DE602005019167T Active DE602005019167D1 (de) 2004-07-20 2005-07-19 Angiopoietin-like 4 protein hemmer kombinationen und deren verwendung

Country Status (23)

Country Link
US (2) US7740846B2 (de)
EP (3) EP1771474B1 (de)
JP (2) JP4947717B2 (de)
KR (1) KR101254815B1 (de)
CN (2) CN101044164A (de)
AT (1) ATE456579T1 (de)
AU (2) AU2005269716B2 (de)
BR (1) BRPI0513534A (de)
CA (1) CA2574758A1 (de)
CY (1) CY1109931T1 (de)
DE (1) DE602005019167D1 (de)
DK (1) DK1771474T3 (de)
ES (1) ES2339789T3 (de)
IL (1) IL180725A0 (de)
MX (1) MX2007000784A (de)
NO (1) NO20070951L (de)
NZ (1) NZ552956A (de)
PL (1) PL1771474T3 (de)
PT (1) PT1771474E (de)
RU (1) RU2392966C2 (de)
SI (1) SI1771474T1 (de)
WO (1) WO2006014729A2 (de)
ZA (1) ZA200701183B (de)

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