DE602005008622D1 - Neue tellurium-verbindungen und ihre verwendung als immunmodulatoren - Google Patents
Neue tellurium-verbindungen und ihre verwendung als immunmodulatorenInfo
- Publication number
- DE602005008622D1 DE602005008622D1 DE602005008622T DE602005008622T DE602005008622D1 DE 602005008622 D1 DE602005008622 D1 DE 602005008622D1 DE 602005008622 T DE602005008622 T DE 602005008622T DE 602005008622 T DE602005008622 T DE 602005008622T DE 602005008622 D1 DE602005008622 D1 DE 602005008622D1
- Authority
- DE
- Germany
- Prior art keywords
- immunomodulators
- tellurium compounds
- new
- new tellurium
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000002955 immunomodulating agent Substances 0.000 title 1
- 229940121354 immunomodulator Drugs 0.000 title 1
- 150000003498 tellurium compounds Chemical class 0.000 title 1
- 102100035904 Caspase-1 Human genes 0.000 abstract 2
- 108090000426 Caspase-1 Proteins 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 229910052714 tellurium Inorganic materials 0.000 abstract 1
- PORWMNRCUJJQNO-UHFFFAOYSA-N tellurium atom Chemical compound [Te] PORWMNRCUJJQNO-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C395/00—Compounds containing tellurium
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F11/00—Compounds containing elements of Groups 6 or 16 of the Periodic Table
- C07F11/005—Compounds containing elements of Groups 6 or 16 of the Periodic Table compounds without a metal-carbon linkage
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Cardiology (AREA)
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- Dermatology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
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- Addiction (AREA)
- Obesity (AREA)
- Molecular Biology (AREA)
- Ophthalmology & Optometry (AREA)
- Biochemistry (AREA)
- AIDS & HIV (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61066004P | 2004-09-17 | 2004-09-17 | |
PCT/IL2005/000989 WO2006030437A2 (en) | 2004-09-17 | 2005-09-15 | Novel tellurium compounds and their use as immunomodulators |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005008622D1 true DE602005008622D1 (de) | 2008-09-11 |
Family
ID=35985262
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005008622T Active DE602005008622D1 (de) | 2004-09-17 | 2005-09-15 | Neue tellurium-verbindungen und ihre verwendung als immunmodulatoren |
Country Status (11)
Country | Link |
---|---|
US (5) | US20090269418A1 (de) |
EP (3) | EP1802292A4 (de) |
JP (1) | JP2008513439A (de) |
AT (1) | ATE402709T1 (de) |
AU (1) | AU2005283719A1 (de) |
CA (3) | CA2580642C (de) |
DE (1) | DE602005008622D1 (de) |
ES (2) | ES2614113T3 (de) |
HK (1) | HK1103355A1 (de) |
PT (1) | PT1796660T (de) |
WO (3) | WO2006030439A2 (de) |
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AU2004304716B2 (en) | 2003-12-18 | 2010-05-27 | Biomas Ltd. | Tellurium derivatives for prevention and treatment of neurodegenerative processes |
JP4903057B2 (ja) * | 2004-01-22 | 2012-03-21 | バイオマス リミテッド | いぼをテルル化合物により治療するための治療法および医薬組成物 |
CA2580642C (en) * | 2004-09-17 | 2014-09-02 | Biomas, Ltd. | Novel tellurium compounds and their use as immunomodulators |
CA2580805A1 (en) * | 2004-09-17 | 2006-03-23 | Biomas Ltd. | Use of tellurium compounds as adjuvants |
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EP1924254A4 (de) * | 2005-09-15 | 2011-01-19 | Biomas Ltd | Verwendung von tellurium-verbindungen zum schutz vor ultravioletter strahlung |
EP1862166A1 (de) * | 2006-06-01 | 2007-12-05 | Yolanda Rodemer | Verwendung von Allopurinol zur behandlung von palmar-plantarer Erythrodysesthesie |
DK2035006T3 (da) * | 2006-06-01 | 2010-04-19 | Nobera Pharma Sl | Anvendelse af allopurinol til behandling af palmar-plantar erythrodysestesi |
WO2008032227A2 (en) | 2006-09-11 | 2008-03-20 | Biomas, Ltd. | Topical formulations of tellurium-containing compounds |
LT2826371T (lt) * | 2007-11-23 | 2019-06-25 | Feramda Ltd. | Būdai ir kompozicijos, skirti integrinų slopinimui naudojant telūro turinčius junginius |
WO2009066301A2 (en) * | 2007-11-23 | 2009-05-28 | Biomas Ltd. | Methods and compositions for treating pox virus with tellurium-containing compounds |
US20110275709A1 (en) * | 2009-01-08 | 2011-11-10 | Biomas Ltd. | Tellurium-containing compounds for affecting male's fertility following chemotherapy and/or radiotherapy |
EP2385758A4 (de) * | 2009-01-08 | 2013-01-23 | Biomas Ltd | Tellurhaltige verbindungen zur manipulation des weiblichen fortpflanzungssystems nach einer chemotherapie und/oder strahlentherapie |
EP2246057A1 (de) | 2009-04-29 | 2010-11-03 | Nobera Pharma, S.L. | Verwendung von Allopurinol zur Behandlung der Hand-Fuß-Hautreaktion |
WO2010146547A1 (en) * | 2009-06-16 | 2010-12-23 | Biomas Ltd. | Tellurium-containing compounds for facilitating transplantation |
CA2774999A1 (en) | 2009-09-30 | 2011-04-07 | President And Fellows Of Harvard College | Methods for modulation of autophagy through the modulation of autophagy-enhancing gene products |
WO2012065065A1 (en) * | 2010-11-12 | 2012-05-18 | Follica, Inc. | Methods and compositions for modulating hair growth, wound healing and scar revision |
EP2648676A4 (de) | 2010-12-06 | 2016-05-04 | Follica Inc | Verfahren zur behandlung von kahlköpfigkeit und zur förderung des haarwuchses |
US11497767B2 (en) | 2015-02-18 | 2022-11-15 | Enlivex Therapeutics R&D Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
US11000548B2 (en) | 2015-02-18 | 2021-05-11 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
US11304976B2 (en) | 2015-02-18 | 2022-04-19 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
WO2016132366A1 (en) | 2015-02-18 | 2016-08-25 | Enlivex Therapeutics Ltd. | Combination immune therapy and cytokine control therapy for cancer treatment |
US11596652B2 (en) | 2015-02-18 | 2023-03-07 | Enlivex Therapeutics R&D Ltd | Early apoptotic cells for use in treating sepsis |
US11318163B2 (en) | 2015-02-18 | 2022-05-03 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
CN107708811B (zh) | 2015-04-21 | 2021-04-30 | 恩立夫克治疗有限责任公司 | 治疗性汇集的血液凋亡细胞制剂与其用途 |
US11730761B2 (en) | 2016-02-18 | 2023-08-22 | Enlivex Therapeutics Rdo Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
US11427538B2 (en) * | 2017-04-28 | 2022-08-30 | Kyoto University | Organic tellurium compound, method for producing same, living radical polymerization initiator, method for producing vinyl polymer, and vinyl polymer |
MX2019015475A (es) | 2017-06-30 | 2020-02-19 | Univ California | Composiciones y metodos para modular el crecimiento del cabello. |
EP3687528A4 (de) * | 2017-09-29 | 2021-07-21 | The Regents of the University of California | Zusammensetzungen und verfahren zur modulation des haarwachstums |
JP2021042161A (ja) * | 2019-09-11 | 2021-03-18 | 国立大学法人東海国立大学機構 | 脱毛剤、脱毛モデル動物及び白髪モデル動物 |
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IL146694A (en) * | 2001-11-22 | 2010-12-30 | Biomas Ltd | Use of an aqueous solution containing a biologically active complex of tellurium dioxide for manufacturing a medicament |
CN100503572C (zh) * | 2002-06-28 | 2009-06-24 | 沃泰克斯药物股份有限公司 | 天冬氨酸特异性半胱氨酸蛋白酶抑制剂及其用途 |
US7612091B2 (en) * | 2002-12-20 | 2009-11-03 | Vertex Pharmaceuticals Incorporated | Caspase inhibitors and uses thereof |
AU2004304716B2 (en) * | 2003-12-18 | 2010-05-27 | Biomas Ltd. | Tellurium derivatives for prevention and treatment of neurodegenerative processes |
WO2006030441A2 (en) | 2004-09-15 | 2006-03-23 | Itamar Medical Ltd. | Measuring blood flow and venous capacitance |
CA2580805A1 (en) * | 2004-09-17 | 2006-03-23 | Biomas Ltd. | Use of tellurium compounds as adjuvants |
CA2580642C (en) | 2004-09-17 | 2014-09-02 | Biomas, Ltd. | Novel tellurium compounds and their use as immunomodulators |
-
2005
- 2005-09-15 CA CA2580642A patent/CA2580642C/en not_active Expired - Fee Related
- 2005-09-15 EP EP05784166A patent/EP1802292A4/de not_active Withdrawn
- 2005-09-15 EP EP05779639.3A patent/EP1796660B1/de not_active Not-in-force
- 2005-09-15 AU AU2005283719A patent/AU2005283719A1/en not_active Abandoned
- 2005-09-15 ES ES05779639.3T patent/ES2614113T3/es active Active
- 2005-09-15 WO PCT/IL2005/000991 patent/WO2006030439A2/en active Application Filing
- 2005-09-15 US US11/662,743 patent/US20090269418A1/en not_active Abandoned
- 2005-09-15 AT AT05779419T patent/ATE402709T1/de not_active IP Right Cessation
- 2005-09-15 DE DE602005008622T patent/DE602005008622D1/de active Active
- 2005-09-15 WO PCT/IL2005/000989 patent/WO2006030437A2/en active IP Right Grant
- 2005-09-15 CA CA2580643A patent/CA2580643C/en not_active Expired - Fee Related
- 2005-09-15 PT PT57796393T patent/PT1796660T/pt unknown
- 2005-09-15 JP JP2007531953A patent/JP2008513439A/ja active Pending
- 2005-09-15 EP EP05779419A patent/EP1791535B1/de not_active Not-in-force
- 2005-09-15 US US11/663,031 patent/US7652065B2/en not_active Expired - Fee Related
- 2005-09-15 US US11/663,032 patent/US7709524B2/en not_active Expired - Fee Related
- 2005-09-15 CA CA002580804A patent/CA2580804A1/en not_active Abandoned
- 2005-09-15 WO PCT/IL2005/000990 patent/WO2006030438A2/en active Application Filing
- 2005-09-15 ES ES05779419T patent/ES2312012T3/es active Active
-
2007
- 2007-10-30 HK HK07111672.5A patent/HK1103355A1/xx not_active IP Right Cessation
-
2009
- 2009-12-02 US US12/629,071 patent/US20100081623A1/en not_active Abandoned
-
2010
- 2010-03-22 US US12/728,362 patent/US8623908B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20080015175A1 (en) | 2008-01-17 |
EP1791535A2 (de) | 2007-06-06 |
CA2580642A1 (en) | 2006-03-23 |
CA2580643C (en) | 2018-06-12 |
WO2006030437A2 (en) | 2006-03-23 |
AU2005283719A1 (en) | 2006-03-23 |
EP1802292A4 (de) | 2008-02-13 |
US8623908B2 (en) | 2014-01-07 |
US20100233294A1 (en) | 2010-09-16 |
WO2006030437A3 (en) | 2006-06-22 |
US20100081623A1 (en) | 2010-04-01 |
CA2580643A1 (en) | 2006-03-23 |
US20090269418A1 (en) | 2009-10-29 |
US7709524B2 (en) | 2010-05-04 |
CA2580642C (en) | 2014-09-02 |
EP1796660A4 (de) | 2008-01-16 |
ES2614113T3 (es) | 2017-05-29 |
WO2006030439A3 (en) | 2007-05-18 |
JP2008513439A (ja) | 2008-05-01 |
EP1802292A2 (de) | 2007-07-04 |
HK1103355A1 (en) | 2007-12-21 |
EP1791535B1 (de) | 2008-07-30 |
WO2006030438A2 (en) | 2006-03-23 |
EP1796660B1 (de) | 2016-11-23 |
ES2312012T3 (es) | 2009-02-16 |
ATE402709T1 (de) | 2008-08-15 |
PT1796660T (pt) | 2017-02-13 |
WO2006030439A2 (en) | 2006-03-23 |
US20070298124A1 (en) | 2007-12-27 |
CA2580804A1 (en) | 2006-03-23 |
WO2006030438A3 (en) | 2006-05-04 |
EP1796660A2 (de) | 2007-06-20 |
US7652065B2 (en) | 2010-01-26 |
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