DE602005006806D1 - Pyrazolderivate, zusammensetzungen, die solche verbindungen enthalten, und anwendungsverfahren - Google Patents
Pyrazolderivate, zusammensetzungen, die solche verbindungen enthalten, und anwendungsverfahrenInfo
- Publication number
- DE602005006806D1 DE602005006806D1 DE602005006806T DE602005006806T DE602005006806D1 DE 602005006806 D1 DE602005006806 D1 DE 602005006806D1 DE 602005006806 T DE602005006806 T DE 602005006806T DE 602005006806 T DE602005006806 T DE 602005006806T DE 602005006806 D1 DE602005006806 D1 DE 602005006806D1
- Authority
- DE
- Germany
- Prior art keywords
- compounds
- methods
- compositions containing
- pyrazole derivatives
- pyrazole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57711604P | 2004-06-04 | 2004-06-04 | |
PCT/US2005/018828 WO2005121097A2 (en) | 2004-06-04 | 2005-05-31 | Pyrazole derivatives, compositions containing such compounds and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005006806D1 true DE602005006806D1 (de) | 2008-06-26 |
Family
ID=35335786
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005006806T Active DE602005006806D1 (de) | 2004-06-04 | 2005-05-31 | Pyrazolderivate, zusammensetzungen, die solche verbindungen enthalten, und anwendungsverfahren |
Country Status (34)
Country | Link |
---|---|
US (2) | US7598285B2 (de) |
EP (1) | EP1756064B1 (de) |
JP (2) | JP4108739B2 (de) |
CN (1) | CN1964947A (de) |
AR (2) | AR049291A1 (de) |
AT (1) | ATE395338T1 (de) |
AU (2) | AU2005252183B2 (de) |
BR (1) | BRPI0511703B8 (de) |
CA (1) | CA2566945C (de) |
CR (1) | CR8766A (de) |
CY (1) | CY1108544T1 (de) |
DE (1) | DE602005006806D1 (de) |
DK (1) | DK1756064T3 (de) |
EA (1) | EA012431B1 (de) |
EC (1) | ECSP067062A (de) |
ES (1) | ES2306165T3 (de) |
GE (1) | GEP20094605B (de) |
HR (1) | HRP20080311T3 (de) |
IL (1) | IL179754A (de) |
MA (1) | MA28673B1 (de) |
MX (1) | MXPA06014084A (de) |
MY (1) | MY143599A (de) |
NI (1) | NI200600290A (de) |
NO (1) | NO339149B1 (de) |
NZ (1) | NZ551405A (de) |
PE (1) | PE20060427A1 (de) |
PL (1) | PL1756064T3 (de) |
PT (1) | PT1756064E (de) |
SI (1) | SI1756064T1 (de) |
TN (1) | TNSN06397A1 (de) |
TW (1) | TWI293952B (de) |
UA (1) | UA85884C2 (de) |
WO (1) | WO2005121097A2 (de) |
ZA (1) | ZA200609489B (de) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7572922B2 (en) | 2003-01-27 | 2009-08-11 | Merck & Co., Inc. | Substituted pyrazoles, compositions containing such compounds and methods of use |
AU2005252183B2 (en) | 2004-06-04 | 2008-07-17 | Merck Sharp & Dohme Corp. | Pyrazole derivatives, compositions containing such compounds and methods of use |
JP2008507528A (ja) * | 2004-07-22 | 2008-03-13 | メルク エンド カムパニー インコーポレーテッド | 置換ピラゾール、このような化合物を含有する組成物及び使用方法 |
CN101300232A (zh) * | 2005-07-26 | 2008-11-05 | 默克公司 | 合成取代的吡唑的方法 |
AR056574A1 (es) * | 2005-10-19 | 2007-10-10 | Merck & Co Inc | Derivados de pirazol, composiciones que contienen dichos compuestos y procedimientos de uso |
US20100099712A1 (en) * | 2007-01-17 | 2010-04-22 | Laboratorios Del Dr. Esteve, S.A. | Substituted pyrazoline compounds with acat inhibition activity |
CA2894112C (en) | 2007-02-09 | 2020-09-15 | Metabasis Therapeutics, Inc. | Novel antagonists of the glucagon receptor |
EP2170337A4 (de) * | 2007-06-28 | 2013-12-18 | Abbvie Inc | Neue triazolopyridazine |
WO2009035558A1 (en) * | 2007-09-12 | 2009-03-19 | Merck & Co., Inc. | Process for the production of a crystalline glucagon receptor antagonist compound |
EA019752B1 (ru) * | 2008-03-05 | 2014-06-30 | Такеда Фармасьютикал Компани Лимитед | Гетероциклическое амидное соединение и его применение для лечения/профилактики диабета |
CA2718255C (en) | 2008-03-11 | 2016-08-23 | Aska Pharmaceutical Co., Ltd. | Solid dispersion and pharmaceutical composition of the same, and production processes thereof |
AU2009246424A1 (en) | 2008-05-16 | 2009-11-19 | Schering Corporation | Glucagon receptor antagonists, compositions, and methods for their use |
US8907103B2 (en) | 2008-08-13 | 2014-12-09 | Metabasis Therapeutics, Inc. | Glucagon antagonists |
RU2008135294A (ru) * | 2008-08-29 | 2010-03-10 | Дик Корпорейшн (Jp) | Нафталиновые производные |
US8436015B2 (en) * | 2008-09-15 | 2013-05-07 | Merck Sharp & Dohme Corp. | Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use |
WO2010039789A1 (en) * | 2008-10-03 | 2010-04-08 | Schering Corporation | Spiro-imidazolone derivatives as glucagon receptor antagonists |
US8324384B2 (en) | 2009-02-12 | 2012-12-04 | Merck Sharp & Dohme Corp. | Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use |
WO2010098994A1 (en) | 2009-02-25 | 2010-09-02 | Merck Sharp & Dohme Corp. | Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use |
US8470773B2 (en) | 2009-06-12 | 2013-06-25 | Merck Sharp & Dohme Corp. | Thiophenes as glucagon receptor antagonists, compositions, and methods for their use |
WO2011037815A1 (en) | 2009-09-22 | 2011-03-31 | Schering Corporation | Novel pyrrolidines as glucagon receptor antagonists, compositions, and methods for their use |
CN103261165B (zh) | 2010-12-23 | 2015-08-26 | 辉瑞公司 | 胰高血糖素受体调节剂 |
JP5562495B2 (ja) | 2011-02-08 | 2014-07-30 | ファイザー・インク | グルカゴン受容体モジュレーター |
ES2550345T3 (es) | 2011-07-22 | 2015-11-06 | Pfizer Inc. | Moduladores del receptor de quinolinilglucagón |
TW201427658A (zh) * | 2012-12-10 | 2014-07-16 | Merck Sharp & Dohme | 藉由投予升糖素受體拮抗劑及膽固醇吸收抑制劑治療糖尿病之方法 |
WO2015066252A1 (en) | 2013-11-04 | 2015-05-07 | Merck Sharp & Dohme Corp. | Glucagon receptor antagonist compounds, compositions thereof, and methods of use |
CN103933032B (zh) * | 2013-12-30 | 2019-08-23 | 北京赛林泰医药技术有限公司 | 作为抗癌药物的吡唑类衍生物的使用方法和用途 |
US10076504B2 (en) | 2014-06-12 | 2018-09-18 | Ligand Pharmaceuticals, Inc. | Glucagon antagonists |
KR20190044079A (ko) | 2016-08-30 | 2019-04-29 | 리제너론 파마슈티칼스 인코포레이티드 | 글루카곤 수용체 신호전달을 간섭함에 의한 중증 인슐린 저항성의 치료 방법 |
TWI763705B (zh) * | 2016-09-06 | 2022-05-11 | 比利時商健生藥品公司 | 可作為升糖素受體拮抗劑之吲哚衍生物 |
US20190248888A1 (en) | 2016-10-20 | 2019-08-15 | Regeneron Pharmaceuticals, Inc. | Methods of lowering blood glucose levels |
EP3672620A1 (de) | 2017-08-22 | 2020-07-01 | Regeneron Pharmaceuticals, Inc. | Verfahren zur behandlung von harnstoffzyklusstörungen durch interferenz mit glucagon-rezeptorsignalisierung |
CN111954560A (zh) | 2018-02-13 | 2020-11-17 | 配体药物公司 | 胰高血糖素受体拮抗剂 |
Family Cites Families (35)
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GB9303993D0 (en) | 1993-02-26 | 1993-04-14 | Fujisawa Pharmaceutical Co | New heterocyclic derivatives |
AU702887B2 (en) | 1995-10-31 | 1999-03-11 | Merck & Co., Inc. | Substituted pyridyl pyrroles, compositions containing such compounds and methods of use |
AR008789A1 (es) | 1996-07-31 | 2000-02-23 | Bayer Corp | Piridinas y bifenilos substituidos |
US5776954A (en) | 1996-10-30 | 1998-07-07 | Merck & Co., Inc. | Substituted pyridyl pyrroles, compositions containing such compounds and methods of use |
AU726311B2 (en) | 1996-11-20 | 2000-11-02 | Merck & Co., Inc. | Triaryl substituted imidazoles and methods of use |
WO1998021957A1 (en) | 1996-11-20 | 1998-05-28 | Merck & Co., Inc. | Triaryl substituted imidazoles, compositions containing such compounds and methods of use |
WO1998022109A1 (en) | 1996-11-20 | 1998-05-28 | Merck & Co., Inc. | Triaryl substituted imidazoles as glucagon antagonists |
DE69719544T2 (de) | 1996-12-12 | 2003-11-06 | Banyu Pharma Co Ltd | Pyrazolderivate |
HUP0001777A3 (en) | 1997-04-18 | 2001-07-30 | G D Searle & Co Chicago | Use of cyclooxygenase-2 inhibitors for producing medicaments useful for the prevention of cardiovascular disorders |
US6613942B1 (en) | 1997-07-01 | 2003-09-02 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
CN1282319A (zh) | 1997-10-09 | 2001-01-31 | 小野药品工业株式会社 | 氨基丁酸衍生物 |
CN1284945A (zh) | 1997-12-19 | 2001-02-21 | 安姆根有限公司 | 取代的吡啶和哒嗪化合物及其药物用途 |
HUP0104240A2 (hu) | 1998-09-17 | 2002-03-28 | Bristol-Myers Squibb Company | Eljárás ateroszklerozis kezelésére egy aP2 inhibítor vagy kombinációja alkalmazásával |
US6503949B1 (en) | 1999-05-17 | 2003-01-07 | Noro Nordisk A/S | Glucagon antagonists/inverse agonists |
CA2381532A1 (en) | 1999-08-10 | 2001-02-15 | Akihiko Yanagi | Herbicidal tetrazolinone derivatives |
BR0015466A (pt) * | 1999-11-10 | 2002-08-06 | Takeda Chemical Industries Ltd | Composto, prodroga, composição farmacêutica, agentes para evitar ou tratar diabetes mellitus, hiperlipidemia e toler ncia à glicose prejudicada, para regular a função do receptor relacionado a retinóide e para melhorar a resistência à insulina e uso de um composto |
US6562807B2 (en) | 2000-06-23 | 2003-05-13 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
JP2004513076A (ja) * | 2000-07-25 | 2004-04-30 | メルク エンド カムパニー インコーポレーテッド | 糖尿病治療で有用なn−置換インドール類 |
US20030203946A1 (en) | 2000-11-17 | 2003-10-30 | Carsten Behrens | Glucagon antagonists/inverse agonists |
WO2002040444A1 (en) | 2000-11-17 | 2002-05-23 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
ITMI20010733A1 (it) | 2001-04-05 | 2002-10-05 | Recordati Chem Pharm | Uso di inibitori dell'isoenzina cox-2 per il trattamento dell'incontinenza urinaria |
US6881746B2 (en) | 2001-12-03 | 2005-04-19 | Novo Nordick A/S | Glucagon antagonists/inverse agonists |
US6762318B2 (en) | 2001-12-03 | 2004-07-13 | Novo Nordisk A/S | Glucagon antagonists |
AU2002351730A1 (en) | 2001-12-19 | 2003-06-30 | Novo Nordisk A/S | Glucagon receptor antagonists/inverse agonists |
AU2002347022A1 (en) | 2001-12-20 | 2003-07-09 | Novo Nordisk A/S | Benzimidazols and indols as glucagon receptor antagonists/inverse agonisten |
KR20090083491A (ko) | 2002-02-01 | 2009-08-03 | 다이닛본 스미토모 세이야꾸 가부시끼가이샤 | 2-퓨란 카르복시산 하이드라지드 화합물 및 그것을 함유하는 의약 조성물 |
MXPA05000816A (es) | 2002-07-19 | 2005-04-28 | Baxter Int | Sistemas y metodos para realizar dialisis peritoneal. |
EP1400243A1 (de) | 2002-09-19 | 2004-03-24 | Tanabe Seiyaku Co., Ltd. | Aktivator von Kalzium-abhängiger Kaliumkanälen |
WO2004050039A2 (en) * | 2002-12-04 | 2004-06-17 | Merck & Co., Inc. | Spirocyclic ureas, compositions containing such compounds and methods of use |
US7572922B2 (en) | 2003-01-27 | 2009-08-11 | Merck & Co., Inc. | Substituted pyrazoles, compositions containing such compounds and methods of use |
CN1794989A (zh) * | 2003-04-14 | 2006-06-28 | 药物研发有限责任公司 | 用于治疗糖尿病的n-(((((1,3-噻唑-2-基)氨基)羰基)苯基)磺酰基)苯丙氨酸衍生物及相关化合物 |
EP1626717A4 (de) * | 2003-05-09 | 2009-09-09 | Merck & Co Inc | Benzimidazole, diese verbindungen enthaltende zusammensetzungen und anwendungsverfahren |
AU2005252183B2 (en) | 2004-06-04 | 2008-07-17 | Merck Sharp & Dohme Corp. | Pyrazole derivatives, compositions containing such compounds and methods of use |
JP2008507528A (ja) * | 2004-07-22 | 2008-03-13 | メルク エンド カムパニー インコーポレーテッド | 置換ピラゾール、このような化合物を含有する組成物及び使用方法 |
AR056574A1 (es) * | 2005-10-19 | 2007-10-10 | Merck & Co Inc | Derivados de pirazol, composiciones que contienen dichos compuestos y procedimientos de uso |
-
2005
- 2005-05-31 AU AU2005252183A patent/AU2005252183B2/en not_active Ceased
- 2005-05-31 MY MYPI20052470A patent/MY143599A/en unknown
- 2005-05-31 CA CA2566945A patent/CA2566945C/en not_active Expired - Fee Related
- 2005-05-31 UA UAA200700111A patent/UA85884C2/uk unknown
- 2005-05-31 NZ NZ551405A patent/NZ551405A/en not_active IP Right Cessation
- 2005-05-31 PT PT05754758T patent/PT1756064E/pt unknown
- 2005-05-31 GE GEAP20059788A patent/GEP20094605B/en unknown
- 2005-05-31 PL PL05754758T patent/PL1756064T3/pl unknown
- 2005-05-31 JP JP2007515416A patent/JP4108739B2/ja not_active Expired - Fee Related
- 2005-05-31 EP EP05754758A patent/EP1756064B1/de active Active
- 2005-05-31 AT AT05754758T patent/ATE395338T1/de active
- 2005-05-31 WO PCT/US2005/018828 patent/WO2005121097A2/en active IP Right Grant
- 2005-05-31 EA EA200602196A patent/EA012431B1/ru not_active IP Right Cessation
- 2005-05-31 SI SI200530296T patent/SI1756064T1/sl unknown
- 2005-05-31 ES ES05754758T patent/ES2306165T3/es active Active
- 2005-05-31 DK DK05754758T patent/DK1756064T3/da active
- 2005-05-31 DE DE602005006806T patent/DE602005006806D1/de active Active
- 2005-05-31 BR BRPI0511703A patent/BRPI0511703B8/pt not_active IP Right Cessation
- 2005-05-31 MX MXPA06014084A patent/MXPA06014084A/es active IP Right Grant
- 2005-05-31 CN CNA2005800182634A patent/CN1964947A/zh active Pending
- 2005-06-02 PE PE2005000624A patent/PE20060427A1/es not_active Application Discontinuation
- 2005-06-02 AR ARP050102266A patent/AR049291A1/es active IP Right Grant
- 2005-06-03 TW TW094118496A patent/TWI293952B/zh not_active IP Right Cessation
- 2005-06-03 US US11/144,332 patent/US7598285B2/en active Active
-
2006
- 2006-11-15 ZA ZA200609489A patent/ZA200609489B/en unknown
- 2006-11-23 CR CR8766A patent/CR8766A/es unknown
- 2006-11-30 NI NI200600290A patent/NI200600290A/es unknown
- 2006-11-30 IL IL179754A patent/IL179754A/en active IP Right Grant
- 2006-12-01 TN TNP2006000397A patent/TNSN06397A1/en unknown
- 2006-12-04 EC EC2006007062A patent/ECSP067062A/es unknown
- 2006-12-20 MA MA29545A patent/MA28673B1/fr unknown
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2007
- 2007-01-04 NO NO20070073A patent/NO339149B1/no not_active IP Right Cessation
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2008
- 2008-02-05 JP JP2008025035A patent/JP4733153B2/ja not_active Expired - Fee Related
- 2008-07-01 HR HR20080311T patent/HRP20080311T3/xx unknown
- 2008-07-21 CY CY20081100762T patent/CY1108544T1/el unknown
- 2008-09-30 AU AU2008229701A patent/AU2008229701C1/en not_active Ceased
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2009
- 2009-03-17 US US12/405,600 patent/US7799818B2/en active Active
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2012
- 2012-11-20 AR ARP120104354A patent/AR088919A2/es unknown
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