DE602005002653D1 - Stabilisierte zusammensetzungen mit einem therapeutischen wirkstoff; zitronensäure oder einer konjugierten base und chlordioxid - Google Patents

Stabilisierte zusammensetzungen mit einem therapeutischen wirkstoff; zitronensäure oder einer konjugierten base und chlordioxid

Info

Publication number
DE602005002653D1
DE602005002653D1 DE602005002653T DE602005002653T DE602005002653D1 DE 602005002653 D1 DE602005002653 D1 DE 602005002653D1 DE 602005002653 T DE602005002653 T DE 602005002653T DE 602005002653 T DE602005002653 T DE 602005002653T DE 602005002653 D1 DE602005002653 D1 DE 602005002653D1
Authority
DE
Germany
Prior art keywords
citric acid
chlorine dioxide
active substance
therapeutic active
conjugated base
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005002653T
Other languages
English (en)
Other versions
DE602005002653T2 (de
Inventor
Robert T Lyons
Robert S Jordan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Inc
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of DE602005002653D1 publication Critical patent/DE602005002653D1/de
Application granted granted Critical
Publication of DE602005002653T2 publication Critical patent/DE602005002653T2/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE602005002653T 2004-06-09 2005-05-19 Stabilisierte zusammensetzungen mit einem therapeutischen wirkstoff; zitronensäure oder einer konjugierten base und chlordioxid Active DE602005002653T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/865,639 US20050276867A1 (en) 2004-06-09 2004-06-09 Stabilized compositions comprising a therapeutically active agent and an oxidizing preservative
US865639 2004-06-09
PCT/US2005/018026 WO2005123135A1 (en) 2004-06-09 2005-05-19 Stabilized compositions comprising a therapeutically active agent, citric acid or a conjugated base and chlorine dioxide

Publications (2)

Publication Number Publication Date
DE602005002653D1 true DE602005002653D1 (de) 2007-11-08
DE602005002653T2 DE602005002653T2 (de) 2008-07-17

Family

ID=34970420

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005002653T Active DE602005002653T2 (de) 2004-06-09 2005-05-19 Stabilisierte zusammensetzungen mit einem therapeutischen wirkstoff; zitronensäure oder einer konjugierten base und chlordioxid

Country Status (15)

Country Link
US (4) US20050276867A1 (de)
EP (1) EP1753461B1 (de)
JP (1) JP5108517B2 (de)
KR (1) KR101184166B1 (de)
CN (1) CN100579530C (de)
AT (1) ATE374043T1 (de)
AU (1) AU2005253931B2 (de)
BR (1) BRPI0511923A (de)
CA (1) CA2570148C (de)
DE (1) DE602005002653T2 (de)
ES (1) ES2289713T3 (de)
HK (1) HK1104212A1 (de)
MX (1) MXPA06014096A (de)
NZ (1) NZ589247A (de)
WO (1) WO2005123135A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9241918B2 (en) 2005-03-16 2016-01-26 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
US7851504B2 (en) 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
US9561178B2 (en) * 2006-07-25 2017-02-07 Allergan, Inc. Cyclosporin compositions
US20100012892A1 (en) * 2008-07-15 2010-01-21 Basf Catalysts Llc Tooth Whitening Compositions and Methods
DE102009021372A1 (de) * 2009-05-14 2010-11-18 Ursapharm Arzneimittel Gmbh Phosphatfreie pharmazeutische Zusammensetzung zur Glaukombehandlung
AU2010266539A1 (en) * 2009-06-30 2012-01-19 Allergan, Inc. Pharmaceutical ophthalmological liquid compositions containing propionic acid derivatives as a preservative
US20110136872A1 (en) * 2009-12-09 2011-06-09 Burk Robert M Stable aqueous compositions of prostglandin agonist prodrugs and methods for use thereof
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure
EP2714007A2 (de) * 2011-05-27 2014-04-09 Ratiopharm GmbH Augenärztliche zubereitung mit einem pgf2alpha-analogon
JP2013082682A (ja) * 2011-09-29 2013-05-09 Senju Pharmaceut Co Ltd 亜塩素酸塩を含有する水性製剤
AU2012351948A1 (en) 2011-12-16 2014-07-10 Allergan, Inc. Ophthalmic compositions comprising polyvinyl capralactam - polyvinyl acetate - polyethylene glycol graft copolymer
CN108310442B (zh) * 2017-01-17 2021-08-27 台北科技大学 眼科用组合物
TW202014194A (zh) 2018-04-27 2020-04-16 美商歐樂根公司 抗微生物功效增強且毒性降低之亞氯酸鈉組成物
US20220125801A1 (en) * 2019-03-06 2022-04-28 Mankind Pharma Ltd. Ophthalmic composition of bimatoprost
US10881111B1 (en) 2019-11-26 2021-01-05 NEOCL Co., Ltd. Composition for providing room temperature long-term constant-concentration chlorine dioxide solution in aqueous medium and preparation method thereof
US11786538B2 (en) 2019-12-11 2023-10-17 Somerset Therapeutics, Llc Low benzalkonium chloride bimatoprost ophthalmic compositions with effective penetration and preservation properties
US20230293541A1 (en) 2022-03-21 2023-09-21 Somerset Therapeutics, Llc Methods of treating ophthalmic conditions with enhanced penetration compositions of bimatoprost and timolol

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE578918A (de) * 1958-06-11
US3278447A (en) * 1963-12-02 1966-10-11 Cloro Bac Products Inc Process for stabilizing chlorine dioxide solution
JPS60184002A (ja) * 1984-03-01 1985-09-19 Daiichi Seimo Kk 赤腐れ菌又は青海苔の防除剤
US4689215A (en) * 1984-07-30 1987-08-25 Ratcliff Perry A Method and composition for prevention and treatment of oral disease
US4696811A (en) * 1984-07-30 1987-09-29 Ratcliff Perry A Method and composition for prevention and treatment of oral disease
JP2638611B2 (ja) 1988-06-17 1997-08-06 紀久雄 及川 安定化二酸化塩素水溶液の製造法
CA2003198C (en) 1988-11-29 1995-03-21 Anthony J. Dziabo, Jr. Aqueous ophthalmic solutions and method for preserving same
WO1990006126A1 (en) 1988-11-29 1990-06-14 Bio-Cide International, Inc. Disinfectant compositions for ophthalmic devices
JPH02290240A (ja) * 1989-04-28 1990-11-30 Takasugi Seiyaku Kk 凝固状環境浄化組成物
US5246662A (en) * 1989-10-02 1993-09-21 Allergan, Inc. Methods for generating chlorine dioxide and compositions for disinfecting
US5279673A (en) * 1990-01-05 1994-01-18 Allergan, Inc. Methods to disinfect contact lenses
JP2759538B2 (ja) * 1990-01-24 1998-05-28 第一製薬株式会社 マコンブ種苗の赤変病防除方法
JPH04349104A (ja) * 1991-05-07 1992-12-03 Takasugi Seiyaku Kk 粉末又は粒状環境浄化組成物
US5736165A (en) 1993-05-25 1998-04-07 Allergan In-the-eye use of chlorine dioxide-containing compositions
US5538974A (en) * 1994-01-27 1996-07-23 Senju Pharamceutical Co., Ltd. Ophthalmic composition for lowering intraocular pressure
JPH10211265A (ja) * 1997-01-29 1998-08-11 M Y Corp:Kk 消臭・防腐・除菌作用を有する剤
PE20020146A1 (es) * 2000-07-13 2002-03-31 Upjohn Co Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2)
WO2002072105A2 (en) * 2001-02-21 2002-09-19 Alcon, Inc. Improved prostanoid therapies for the treatment of glaucoma
US6982079B2 (en) * 2002-04-26 2006-01-03 Allergan, Inc. Compositions for treating hyperemia

Also Published As

Publication number Publication date
CA2570148A1 (en) 2005-12-29
JP5108517B2 (ja) 2012-12-26
WO2005123135A1 (en) 2005-12-29
US8343949B2 (en) 2013-01-01
HK1104212A1 (en) 2008-01-11
ES2289713T3 (es) 2008-02-01
AU2005253931B2 (en) 2011-05-19
US20130090387A1 (en) 2013-04-11
KR20070028405A (ko) 2007-03-12
EP1753461B1 (de) 2007-09-26
US20150283240A1 (en) 2015-10-08
EP1753461A1 (de) 2007-02-21
KR101184166B1 (ko) 2012-09-19
CN100579530C (zh) 2010-01-13
ATE374043T1 (de) 2007-10-15
CN1964743A (zh) 2007-05-16
MXPA06014096A (es) 2007-01-31
US20080300315A1 (en) 2008-12-04
US8691802B2 (en) 2014-04-08
NZ589247A (en) 2012-06-29
CA2570148C (en) 2012-10-23
WO2005123135A8 (en) 2006-06-22
BRPI0511923A (pt) 2008-01-22
DE602005002653T2 (de) 2008-07-17
JP2008502723A (ja) 2008-01-31
AU2005253931A1 (en) 2005-12-29
US20050276867A1 (en) 2005-12-15

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