DE602005000874D1 - Screening-verfahren unter verwendung von zebrafisch und der blut-hirn-schranke - Google Patents
Screening-verfahren unter verwendung von zebrafisch und der blut-hirn-schrankeInfo
- Publication number
- DE602005000874D1 DE602005000874D1 DE602005000874T DE602005000874T DE602005000874D1 DE 602005000874 D1 DE602005000874 D1 DE 602005000874D1 DE 602005000874 T DE602005000874 T DE 602005000874T DE 602005000874 T DE602005000874 T DE 602005000874T DE 602005000874 D1 DE602005000874 D1 DE 602005000874D1
- Authority
- DE
- Germany
- Prior art keywords
- zebrief
- blood brain
- screening method
- brain barriers
- effect
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Revoked
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0403490 | 2004-02-17 | ||
GBGB0403490.6A GB0403490D0 (en) | 2004-02-17 | 2004-02-17 | Screening methods |
PCT/GB2005/000583 WO2005080974A1 (en) | 2004-02-17 | 2005-02-17 | Screening methods employing zebrafish and the blood brain barrier |
Publications (2)
Publication Number | Publication Date |
---|---|
DE602005000874D1 true DE602005000874D1 (de) | 2007-05-24 |
DE602005000874T2 DE602005000874T2 (de) | 2008-01-17 |
Family
ID=32039873
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005000874T Revoked DE602005000874T2 (de) | 2004-02-17 | 2005-02-17 | Screening-verfahren unter verwendung von zebrafisch und der blut-hirn-schranke |
Country Status (10)
Country | Link |
---|---|
US (1) | US20060193776A1 (de) |
EP (1) | EP1644733B1 (de) |
JP (1) | JP2007525665A (de) |
AT (1) | ATE359508T1 (de) |
AU (1) | AU2005215455A1 (de) |
CA (1) | CA2556680A1 (de) |
DE (1) | DE602005000874T2 (de) |
ES (1) | ES2286794T3 (de) |
GB (1) | GB0403490D0 (de) |
WO (1) | WO2005080974A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE512233T1 (de) | 1998-02-23 | 2011-06-15 | Phylonix Pharmaceuticals Inc | Screeningverfahren für die aktivität von agenzien unter verwendung von teleosten |
US7951989B2 (en) | 1998-02-23 | 2011-05-31 | Phylonix Pharmaceuticals, Inc. | Methods of screening agents for activity using teleosts |
US6656449B1 (en) | 1998-02-23 | 2003-12-02 | Phylonix Pharmaceuticals, Inc. | Methods of screening agents for activity using teleosts |
WO2005098428A2 (en) * | 2004-04-07 | 2005-10-20 | Marinus Pharmaceuticals, Inc. | Method and system for screening compounds for muscular and/or neurological activity in animals |
DK2329265T3 (da) | 2008-09-22 | 2013-12-02 | Entomopharm Aps | Fremgangsmåder til screening, hvor der anvendes insekter med blodhjernebarriere |
WO2011077751A1 (ja) | 2009-12-25 | 2011-06-30 | キヤノン株式会社 | 中枢神経系組織標識用組成物、中枢神経系組織の標識方法、及び中枢神経系組織標識用組成物を用いたスクリーニング方法 |
JP5733715B2 (ja) * | 2009-12-25 | 2015-06-10 | キヤノン株式会社 | 経鼻中枢神経系組織標識用組成物、経鼻中枢神経系組織標識用組成物を用いた標識方法及びスクリーニング方法 |
JP5888904B2 (ja) | 2011-02-16 | 2016-03-22 | 国立大学法人三重大学 | 中枢神経移行性評価用プローブ、中枢神経移行性評価方法、及び、中枢神経移行性評価用プローブを用いたスクリーニング方法 |
CN102288750B (zh) * | 2011-08-12 | 2014-04-16 | 杭州环特生物科技有限公司 | 斑马鱼p-糖蛋白抑制剂筛选模型的建立方法及其应用 |
IL268660B2 (en) | 2017-02-17 | 2024-03-01 | Denali Therapeutics Inc | Polypeptides that bind to a transgenic transferrin receptor, polynucleotides encoding them, methods for their preparation and use |
US10143187B2 (en) | 2017-02-17 | 2018-12-04 | Denali Therapeutics Inc. | Transferrin receptor transgenic models |
US10457717B2 (en) | 2017-02-17 | 2019-10-29 | Denali Therapeutics Inc. | Engineered polypeptides |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE512233T1 (de) * | 1998-02-23 | 2011-06-15 | Phylonix Pharmaceuticals Inc | Screeningverfahren für die aktivität von agenzien unter verwendung von teleosten |
-
2004
- 2004-02-17 GB GBGB0403490.6A patent/GB0403490D0/en not_active Ceased
-
2005
- 2005-02-17 WO PCT/GB2005/000583 patent/WO2005080974A1/en active IP Right Grant
- 2005-02-17 ES ES05708384T patent/ES2286794T3/es active Active
- 2005-02-17 US US10/566,888 patent/US20060193776A1/en not_active Abandoned
- 2005-02-17 AT AT05708384T patent/ATE359508T1/de not_active IP Right Cessation
- 2005-02-17 JP JP2006552695A patent/JP2007525665A/ja active Pending
- 2005-02-17 DE DE602005000874T patent/DE602005000874T2/de not_active Revoked
- 2005-02-17 CA CA002556680A patent/CA2556680A1/en not_active Abandoned
- 2005-02-17 EP EP05708384A patent/EP1644733B1/de not_active Revoked
- 2005-02-17 AU AU2005215455A patent/AU2005215455A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20060193776A1 (en) | 2006-08-31 |
EP1644733B1 (de) | 2007-04-11 |
ES2286794T3 (es) | 2007-12-01 |
EP1644733A1 (de) | 2006-04-12 |
GB0403490D0 (en) | 2004-03-24 |
JP2007525665A (ja) | 2007-09-06 |
DE602005000874T2 (de) | 2008-01-17 |
AU2005215455A1 (en) | 2005-09-01 |
CA2556680A1 (en) | 2005-09-01 |
WO2005080974A1 (en) | 2005-09-01 |
ATE359508T1 (de) | 2007-05-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: SUMMIT (CAMDRIDGE) LTD., CAMBRIDGE, CAMBRIGESH, GB |
|
8331 | Complete revocation |