DE602004024069D1 - SYNTHETIC, BIOABSORBABLE POLYMER MATERIALS AND IMPLANTS - Google Patents
SYNTHETIC, BIOABSORBABLE POLYMER MATERIALS AND IMPLANTSInfo
- Publication number
- DE602004024069D1 DE602004024069D1 DE602004024069T DE602004024069T DE602004024069D1 DE 602004024069 D1 DE602004024069 D1 DE 602004024069D1 DE 602004024069 T DE602004024069 T DE 602004024069T DE 602004024069 T DE602004024069 T DE 602004024069T DE 602004024069 D1 DE602004024069 D1 DE 602004024069D1
- Authority
- DE
- Germany
- Prior art keywords
- matrix
- tissue
- implants
- synthetic
- polymer materials
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/005—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters containing a biologically active substance, e.g. a medicament or a biocide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Materials Engineering (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention relates to synthetic, bioabsorbable polymer materials and implants, like fibres, sutures, meshes and other tissue management, wound closure or tissue engineering devices, which contain: a) a bioabsorbable polymeric matrix; b) antibiotic and/or anti-inflammatory agent particles or mixture thereof, dispersed in the matrix, and c) optionally an additive agent to facilitate device recognition and/or handling to facilitate the use and application of finalized product. In the matrix, cavities around the particles are induced by mechanical processing of the matrix phase. A preferred embodiment of the present invention is a device (suture) that provides a sustained release of antibiotic agent over several days to several weeks for the prevention or treatment of infection. The sutures may be effectively implanted into or in the vicinity of: 1) infected tissue, 2) potentially infected tissue, or in tissues where infection, should it occur, leads to disastrous consequences.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI20031090A FI20031090A (en) | 2003-07-17 | 2003-07-17 | Synthetic bioabsorbable polymeric materials and implants |
FI20045223A FI20045223A (en) | 2004-06-15 | 2004-06-15 | A multifunctional biodegradable composite and a surgical implant comprising said composite |
PCT/IB2004/002318 WO2005007209A1 (en) | 2003-07-17 | 2004-07-19 | Synthetic, bioabsorbable polymer materials and implants |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004024069D1 true DE602004024069D1 (en) | 2009-12-24 |
Family
ID=34081840
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004024069T Active DE602004024069D1 (en) | 2003-07-17 | 2004-07-19 | SYNTHETIC, BIOABSORBABLE POLYMER MATERIALS AND IMPLANTS |
Country Status (5)
Country | Link |
---|---|
US (1) | US20070134292A1 (en) |
EP (1) | EP1646410B1 (en) |
AT (1) | ATE447981T1 (en) |
DE (1) | DE602004024069D1 (en) |
WO (1) | WO2005007209A1 (en) |
Families Citing this family (93)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5931855A (en) | 1997-05-21 | 1999-08-03 | Frank Hoffman | Surgical methods using one-way suture |
GB0113697D0 (en) * | 2001-06-06 | 2001-07-25 | Smith & Nephew | Fixation devices for tissue repair |
US7056331B2 (en) * | 2001-06-29 | 2006-06-06 | Quill Medical, Inc. | Suture method |
US6773450B2 (en) | 2002-08-09 | 2004-08-10 | Quill Medical, Inc. | Suture anchor and method |
FI20045223A (en) * | 2004-06-15 | 2005-12-16 | Bioretec Oy | A multifunctional biodegradable composite and a surgical implant comprising said composite |
NZ598970A (en) | 2004-05-14 | 2013-07-26 | Ethicon Llc | Suture device using an enlongated body with barbs and a needle at one end and an anchor to prevent pull-through at the other end |
US7419681B2 (en) * | 2004-12-02 | 2008-09-02 | Bioretec, Ltd. | Method to enhance drug release from a drug-releasing material |
CA2632871A1 (en) * | 2006-01-30 | 2007-08-09 | Angiotech Pharmaceuticals, Inc. | Sutures and fibrosing agents |
WO2008033533A2 (en) * | 2006-09-15 | 2008-03-20 | Angiotech Pharmaceuticals, Inc. | Composite drug delivery system |
US20080255612A1 (en) | 2007-04-13 | 2008-10-16 | Angiotech Pharmaceuticals, Inc. | Self-retaining systems for surgical procedures |
ES2488406T3 (en) | 2007-09-27 | 2014-08-27 | Ethicon Llc | Self-retaining sutures that include tissue retention elements with enhanced strength |
US8771313B2 (en) | 2007-12-19 | 2014-07-08 | Ethicon, Inc. | Self-retaining sutures with heat-contact mediated retainers |
US8916077B1 (en) | 2007-12-19 | 2014-12-23 | Ethicon, Inc. | Self-retaining sutures with retainers formed from molten material |
US8118834B1 (en) | 2007-12-20 | 2012-02-21 | Angiotech Pharmaceuticals, Inc. | Composite self-retaining sutures and method |
WO2009097556A2 (en) | 2008-01-30 | 2009-08-06 | Angiotech Pharmaceuticals, Inc. | Appartaus and method for forming self-retaining sutures |
US8615856B1 (en) | 2008-01-30 | 2013-12-31 | Ethicon, Inc. | Apparatus and method for forming self-retaining sutures |
EP2247245B1 (en) | 2008-02-18 | 2017-06-28 | Covidien LP | A device for deploying and attaching a patch to a biological tissue |
US9034002B2 (en) | 2008-02-18 | 2015-05-19 | Covidien Lp | Lock bar spring and clip for implant deployment device |
US9833240B2 (en) | 2008-02-18 | 2017-12-05 | Covidien Lp | Lock bar spring and clip for implant deployment device |
US9398944B2 (en) | 2008-02-18 | 2016-07-26 | Covidien Lp | Lock bar spring and clip for implant deployment device |
US8808314B2 (en) | 2008-02-18 | 2014-08-19 | Covidien Lp | Device and method for deploying and attaching an implant to a biological tissue |
US9301826B2 (en) | 2008-02-18 | 2016-04-05 | Covidien Lp | Lock bar spring and clip for implant deployment device |
US8758373B2 (en) | 2008-02-18 | 2014-06-24 | Covidien Lp | Means and method for reversibly connecting a patch to a patch deployment device |
US8317808B2 (en) | 2008-02-18 | 2012-11-27 | Covidien Lp | Device and method for rolling and inserting a prosthetic patch into a body cavity |
US9393002B2 (en) | 2008-02-18 | 2016-07-19 | Covidien Lp | Clip for implant deployment device |
US9044235B2 (en) | 2008-02-18 | 2015-06-02 | Covidien Lp | Magnetic clip for implant deployment device |
US9393093B2 (en) | 2008-02-18 | 2016-07-19 | Covidien Lp | Clip for implant deployment device |
EP2249712B8 (en) | 2008-02-21 | 2018-12-26 | Ethicon LLC | Method and apparatus for elevating retainers on self-retaining sutures |
US8641732B1 (en) | 2008-02-26 | 2014-02-04 | Ethicon, Inc. | Self-retaining suture with variable dimension filament and method |
SG188784A1 (en) | 2008-04-15 | 2013-04-30 | Ethicon Llc | Self-retaining sutures with bi-directional retainers or uni-directional retainers |
US8961560B2 (en) | 2008-05-16 | 2015-02-24 | Ethicon, Inc. | Bidirectional self-retaining sutures with laser-marked and/or non-laser marked indicia and methods |
AU2009257230B2 (en) * | 2008-06-13 | 2015-05-28 | Smith & Nephew, Inc. | Fixation devices for tissue repair |
EP2303026B1 (en) | 2008-06-17 | 2020-09-09 | Brigham Young University | Cationic steroid antimicrobial diagnostic, detection, screening and imaging methods |
CA2730547C (en) | 2008-10-20 | 2013-08-06 | Polytouch Medical Ltd. | A device for attaching a patch to a biological tissue |
US8932328B2 (en) | 2008-11-03 | 2015-01-13 | Ethicon, Inc. | Length of self-retaining suture and method and device for using the same |
US8460350B2 (en) * | 2009-06-19 | 2013-06-11 | Arthrex, Inc. | Graft protection mesh and fixation technique |
EP2467093B1 (en) | 2009-08-17 | 2019-08-28 | Covidien LP | Articulating patch deployment device |
EP3508144B1 (en) | 2009-08-17 | 2021-04-07 | Covidien LP | Patch deployment device |
KR20170121318A (en) | 2010-05-04 | 2017-11-01 | 에티컨, 엘엘씨 | Self-retaining systems having laser-cut retainers |
NZ604320A (en) | 2010-06-11 | 2014-07-25 | Ethicon Llc | Suture delivery tools for endoscopic and robot-assisted surgery and methods |
US9107983B2 (en) | 2010-10-27 | 2015-08-18 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising statins |
WO2012061658A2 (en) | 2010-11-03 | 2012-05-10 | Angiotech Pharmaceuticals, Inc. | Drug-eluting self-retaining sutures and methods relating thereto |
AU2011326446B2 (en) | 2010-11-09 | 2016-03-03 | Ethicon, Llc | Emergency self-retaining sutures and packaging |
RU2456942C1 (en) * | 2010-12-27 | 2012-07-27 | Иван Васильевич Крайник | Method of hernioplasty |
RU2659454C2 (en) | 2011-03-23 | 2018-07-02 | ЭТИКОН ЭлЭлСи | Self-retaining variable loop sutures |
US20130172931A1 (en) | 2011-06-06 | 2013-07-04 | Jeffrey M. Gross | Methods and devices for soft palate tissue elevation procedures |
US20130030243A1 (en) * | 2011-07-28 | 2013-01-31 | Boston Scientific Scimed, Inc. | Anti-bacterial surgical meshes |
US9179994B2 (en) * | 2011-10-25 | 2015-11-10 | Covidien Lp | Implantable film/mesh composite |
ITFI20120041A1 (en) * | 2012-02-29 | 2013-08-30 | Univ Palermo | NEW MULTIFUNCTIONAL SUTURE THREADS WITH RELEASE OF ANTIMICROBIAL, ANTIBIOTIC, CICATRIZING SUBSTANCES. |
CA2872399C (en) | 2012-05-02 | 2021-01-12 | Brigham Young University | Ceragenin particulate materials and methods for making same |
KR20180083969A (en) * | 2012-10-04 | 2018-07-23 | 나노코 테크놀로지스 리미티드 | Illuminated signage using quantum dots |
EP2919823B1 (en) * | 2012-11-14 | 2019-07-03 | Orthopaedic Innovation Centre Inc. | Antimicrobial articles produced by additive manufacturing |
EP2941253B1 (en) | 2013-01-07 | 2021-08-11 | Brigham Young University | Cationic steroid antimicrobial agents for use in treating cancer |
AU2014227794B2 (en) | 2013-03-15 | 2018-03-01 | Cook Biotech Incorporated | Drug eluting graft constructs and methods |
US11524015B2 (en) | 2013-03-15 | 2022-12-13 | Brigham Young University | Methods for treating inflammation, autoimmune disorders and pain |
CA2907082C (en) | 2013-03-15 | 2021-05-04 | Brigham Young University | Methods for treating inflammation, autoimmune disorders and pain |
US10568893B2 (en) | 2013-03-15 | 2020-02-25 | Brigham Young University | Methods for treating inflammation, autoimmune disorders and pain |
US11690855B2 (en) | 2013-10-17 | 2023-07-04 | Brigham Young University | Methods for treating lung infections and inflammation |
US20150203527A1 (en) | 2014-01-23 | 2015-07-23 | Brigham Young University | Cationic steroidal antimicrobials |
CA2844321C (en) | 2014-02-27 | 2021-03-16 | Brigham Young University | Cationic steroidal antimicrobial compounds |
US10220045B2 (en) | 2014-03-13 | 2019-03-05 | Brigham Young University | Compositions and methods for forming stabilized compositions with reduced CSA agglomeration |
US9931350B2 (en) | 2014-03-14 | 2018-04-03 | Brigham Young University | Anti-infective and osteogenic compositions and methods of use |
US10441595B2 (en) | 2014-06-26 | 2019-10-15 | Brigham Young University | Methods for treating fungal infections |
US10238665B2 (en) | 2014-06-26 | 2019-03-26 | Brigham Young University | Methods for treating fungal infections |
US10227376B2 (en) | 2014-08-22 | 2019-03-12 | Brigham Young University | Radiolabeled cationic steroid antimicrobials and diagnostic methods |
US10155788B2 (en) | 2014-10-07 | 2018-12-18 | Brigham Young University | Cationic steroidal antimicrobial prodrug compositions and uses thereof |
GB201505527D0 (en) | 2015-03-31 | 2015-05-13 | Jmedtech Pte Ltd | Composition |
US10245034B2 (en) | 2015-08-31 | 2019-04-02 | Ethicon Llc | Inducing tissue adhesions using surgical adjuncts and medicants |
US10130738B2 (en) | 2015-08-31 | 2018-11-20 | Ethicon Llc | Adjunct material to promote tissue growth |
US10076324B2 (en) | 2015-08-31 | 2018-09-18 | Ethicon Llc | Adjunct material to provide controlled drug elution |
US9937283B2 (en) | 2015-08-31 | 2018-04-10 | Ethicon Endo-Surgery, Llc | Adjunct material to provide drug elution from vessels |
US10188390B2 (en) | 2015-08-31 | 2019-01-29 | Ethicon Llc | Adjunct material to provide heterogeneous drug elution |
US10463366B2 (en) | 2015-08-31 | 2019-11-05 | Ethicon Llc | Adjunct materials for delivery to liver tissue |
US10279086B2 (en) | 2015-08-31 | 2019-05-07 | Ethicon Llc | Composite adjunct materials for delivering medicants |
US10499913B2 (en) | 2015-08-31 | 2019-12-10 | Ethicon Llc | Tubular surgical constructs including adjunct material |
US10086116B2 (en) | 2015-08-31 | 2018-10-02 | Ethicon Llc | Adjunct material to provide controlled drug release |
US10194936B2 (en) | 2015-08-31 | 2019-02-05 | Ethicon Endo-Surgery, Llc | Adjunct material for delivery to stomach tissue |
US10188389B2 (en) | 2015-08-31 | 2019-01-29 | Ethicon Llc | Adjunct material for delivery to colon tissue |
US10111661B2 (en) | 2015-08-31 | 2018-10-30 | Ethicon Llc | Matrix metalloproteinase inhibiting adjuncts for surgical devices |
US10349938B2 (en) | 2015-08-31 | 2019-07-16 | Ethicon Llc | Surgical adjuncts with medicants affected by activator materials |
US11020116B2 (en) | 2015-08-31 | 2021-06-01 | Ethicon Llc | Surgical adjuncts with medicants affected by activators |
US10285692B2 (en) | 2015-08-31 | 2019-05-14 | Ethicon Llc | Adjuncts for surgical devices including agonists and antagonists |
US10213520B2 (en) | 2015-08-31 | 2019-02-26 | Ethicon Llc | Surgical adjuncts having medicants controllably releasable therefrom |
US10076329B2 (en) | 2015-08-31 | 2018-09-18 | Ethicon Llc | Adjunct material to promote tissue growth in a colon |
US10569071B2 (en) | 2015-08-31 | 2020-02-25 | Ethicon Llc | Medicant eluting adjuncts and methods of using medicant eluting adjuncts |
US10172973B2 (en) | 2015-08-31 | 2019-01-08 | Ethicon Llc | Surgical adjuncts and medicants for promoting lung function |
US20170080128A1 (en) * | 2015-09-21 | 2017-03-23 | Brigham Young University | Novel endotracheal tube for the reduction of intubation-related complication in neonates and babies |
US10226550B2 (en) | 2016-03-11 | 2019-03-12 | Brigham Young University | Cationic steroidal antimicrobial compositions for the treatment of dermal tissue |
US20180221021A1 (en) * | 2017-02-08 | 2018-08-09 | Ethicon, Inc. | Braided suture with filament containing a medicant |
US10959433B2 (en) | 2017-03-21 | 2021-03-30 | Brigham Young University | Use of cationic steroidal antimicrobials for sporicidal activity |
WO2019071246A2 (en) | 2017-10-06 | 2019-04-11 | Foundry Therapeutics, Inc. | Implantable depots for controlled release of analgesics to treat postoperative pain, and associated devices, systems, and methods |
CN111683622B (en) | 2017-11-14 | 2024-06-18 | 伊根设计有限责任公司 | Electrolessly bondable wire material and apparatus and methods for forming welded wire loops and other welded structures |
WO2023140423A1 (en) * | 2022-01-21 | 2023-07-27 | 주식회사 큐어팜텍 | Absorbable suture containing celecoxib and preparation method therefor |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6406498B1 (en) * | 1998-09-04 | 2002-06-18 | Bionx Implants Oy | Bioactive, bioabsorbable surgical composite material |
US6579533B1 (en) * | 1999-11-30 | 2003-06-17 | Bioasborbable Concepts, Ltd. | Bioabsorbable drug delivery system for local treatment and prevention of infections |
CA2349155A1 (en) * | 2000-05-25 | 2001-11-25 | Ethicon, Inc. | Anti-microbial surgical services |
DE10114247A1 (en) * | 2001-03-22 | 2002-10-10 | Heraeus Kulzer Gmbh & Co Kg | Antibiotic / antibiotics-polymer combination |
-
2004
- 2004-07-19 EP EP04743979A patent/EP1646410B1/en not_active Not-in-force
- 2004-07-19 US US10/565,023 patent/US20070134292A1/en not_active Abandoned
- 2004-07-19 AT AT04743979T patent/ATE447981T1/en not_active IP Right Cessation
- 2004-07-19 WO PCT/IB2004/002318 patent/WO2005007209A1/en active Application Filing
- 2004-07-19 DE DE602004024069T patent/DE602004024069D1/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2005007209A1 (en) | 2005-01-27 |
EP1646410B1 (en) | 2009-11-11 |
ATE447981T1 (en) | 2009-11-15 |
EP1646410A1 (en) | 2006-04-19 |
US20070134292A1 (en) | 2007-06-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |