DE60138829D1 - Verfahren zur unterscheidung des reizkolons von der entzündlichen darmerkrankung (inflammatory bowel disease, ibd) und zur überwachung von patienten mit ibd unter verwendung von endogenem gesamt-lactoferrin als marker - Google Patents

Verfahren zur unterscheidung des reizkolons von der entzündlichen darmerkrankung (inflammatory bowel disease, ibd) und zur überwachung von patienten mit ibd unter verwendung von endogenem gesamt-lactoferrin als marker

Info

Publication number
DE60138829D1
DE60138829D1 DE60138829T DE60138829T DE60138829D1 DE 60138829 D1 DE60138829 D1 DE 60138829D1 DE 60138829 T DE60138829 T DE 60138829T DE 60138829 T DE60138829 T DE 60138829T DE 60138829 D1 DE60138829 D1 DE 60138829D1
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DE
Germany
Prior art keywords
ibd
inflammatory bowel
bowel disease
monitoring
lactoferrine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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DE60138829T
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English (en)
Inventor
James Hunter Boone
David Maxwell Lyerly
Tracy Dale Wilkins
Richard Littleton Guerrant
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Techlab Inc
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Techlab Inc
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Publication date
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Publication of DE60138829D1 publication Critical patent/DE60138829D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/79Transferrins, e.g. lactoferrins, ovotransferrins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/06Gastro-intestinal diseases
    • G01N2800/065Bowel diseases, e.g. Crohn, ulcerative colitis, IBS

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE60138829T 2000-11-14 2001-11-14 Verfahren zur unterscheidung des reizkolons von der entzündlichen darmerkrankung (inflammatory bowel disease, ibd) und zur überwachung von patienten mit ibd unter verwendung von endogenem gesamt-lactoferrin als marker Expired - Lifetime DE60138829D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24828800P 2000-11-14 2000-11-14
PCT/US2001/045301 WO2002039883A2 (en) 2000-11-14 2001-11-14 Method for differentiating between irritable bowel syndrome and inflammatory bowel disease using lactoferrin as marker

Publications (1)

Publication Number Publication Date
DE60138829D1 true DE60138829D1 (de) 2009-07-09

Family

ID=22938469

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60138829T Expired - Lifetime DE60138829D1 (de) 2000-11-14 2001-11-14 Verfahren zur unterscheidung des reizkolons von der entzündlichen darmerkrankung (inflammatory bowel disease, ibd) und zur überwachung von patienten mit ibd unter verwendung von endogenem gesamt-lactoferrin als marker

Country Status (8)

Country Link
US (3) US7192724B2 (de)
EP (2) EP2071332A1 (de)
AT (1) ATE432470T1 (de)
AU (3) AU2002220029B2 (de)
CA (1) CA2427898C (de)
DE (1) DE60138829D1 (de)
ES (1) ES2325059T3 (de)
WO (1) WO2002039883A2 (de)

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US7785818B2 (en) 2002-10-25 2010-08-31 Techlab, Inc. Inflammatory bowel disease and irritable bowel syndrome IBD-first chek diagnostic panel
US7759079B2 (en) * 2004-05-13 2010-07-20 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
US20060154276A1 (en) 2004-05-13 2006-07-13 Prometheus Laboratories Inc. Methods of diagnosing inflammatory bowel disease
US7943328B1 (en) 2006-03-03 2011-05-17 Prometheus Laboratories Inc. Method and system for assisting in diagnosing irritable bowel syndrome
US20100094560A1 (en) * 2006-08-15 2010-04-15 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
US20080085524A1 (en) * 2006-08-15 2008-04-10 Prometheus Laboratories Inc. Methods for diagnosing irritable bowel syndrome
US20100129838A1 (en) 2008-11-11 2010-05-27 Prometheus Laboratories Inc. Methods for prediction of inflammatory bowel disease (ibd) using serologic markers
EP2419529B1 (de) 2009-04-14 2015-05-20 Nestec S.A. Prognostik entzündlicher darmerkrankung
EP2778685B1 (de) 2009-06-25 2017-04-26 Nestec S.A. Verfahren zur diagnostizierung des reizdarmsyndroms
WO2011060098A1 (en) 2009-11-10 2011-05-19 Prometheus Laboratories Inc. Methods for predicting post-surgery risk associated with ileal pouch-anal anastomosis
EP3564357B1 (de) 2010-02-01 2022-04-06 Rebiotix, Inc. Bakterientherapie für clostridium-difficile-colitis
ES2380664B2 (es) 2010-10-19 2012-09-13 Certest Biotec, S.L. Método y dispositivo para el diagnóstico rápido de enfermedades en muestras fecales.
MX343327B (es) 2011-02-17 2016-11-01 Nestec Sa Ensayos para detectar autoanticuerpos contra farmacos anti-tnfa.
US10295535B2 (en) 2011-04-29 2019-05-21 Techlab, Inc. Clostridium difficile dehydrogenase and toxin as a biomarker for monitoring infection in patients with clostridium difficile disease and differentiating carrier state from active disease
US20120276059A1 (en) * 2011-04-29 2012-11-01 Techlab, Inc. Fecal lactoferrin as a biomarker for determining disease severity and for monitoring infection in patients with clostridium difficile disease
WO2012154987A1 (en) 2011-05-10 2012-11-15 Nestec Sa Methods of disease activity profiling for personalized therapy management
WO2013014669A1 (en) 2011-07-24 2013-01-31 Carmel-Haifa University Economic Corp. Lactoferrin fragments and use thereof
US20120258477A1 (en) * 2011-07-25 2012-10-11 Northwestern University Fecal neopterin concentration measurement as an indicator of disease activity in inflammatory bowel disease
WO2013059732A1 (en) 2011-10-21 2013-04-25 Nestec S.A. Methods for improving inflammatory bowel disease diagnosis
WO2013082288A1 (en) * 2011-11-29 2013-06-06 The Regents Of The University Of California Glucorticoid receptor gene nr3c1 methylation in irritable bowel syndrome and other stress disorders
WO2013132347A2 (en) 2012-03-06 2013-09-12 Calpro As Improved elisa immunoassay for calprotectin
WO2013132338A2 (en) 2012-03-06 2013-09-12 Calpro As Competitive immunoassay for calprotectin
CN103575903B (zh) * 2012-08-07 2016-01-20 中国检验检疫科学研究院 一种人乳铁蛋白夹心elisa检测试剂盒及其应用
RU2504779C1 (ru) * 2012-10-08 2014-01-20 Государственное бюджетное образовательное учреждение высшего профессионального образования "Ростовский государственный медицинский университет" Минздравсоцразвития России Способ оценки эффективности лечения больных язвенным колитом
JP6330032B2 (ja) 2013-06-05 2018-05-23 レビオティクス インコーポレイテッドRebiotix,Inc. 微生物叢回復療法組成物を製造、処理、および梱包するための方法
US10383901B2 (en) 2013-06-05 2019-08-20 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9511099B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9782445B2 (en) 2013-06-05 2017-10-10 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9511100B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9694039B2 (en) 2013-06-05 2017-07-04 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
EP3094973B1 (de) 2013-11-07 2020-07-29 Diagnodus Limited Biomarker
US10905726B2 (en) 2015-06-09 2021-02-02 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
BR112017026586B1 (pt) 2015-06-09 2021-11-03 Rebiotix, Inc. Composições de terapia de restauração de microbiota (mrt) e métodos de fabricação
US10828340B2 (en) 2015-06-09 2020-11-10 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
US10799539B2 (en) 2015-06-09 2020-10-13 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
PL3171174T3 (pl) * 2015-11-20 2018-04-30 Geroa Diagnostics, S.L Laktoferryna do zastosowania w diagnostyce lub prognozowaniu choroby Alzheimera

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US4444879A (en) * 1981-01-29 1984-04-24 Science Research Center, Inc. Immunoassay with article having support film and immunological counterpart of analyte
US5124252A (en) * 1989-11-28 1992-06-23 University Of Virginia Alumni Patents Foundation In vitro test for fecal leukocytes
US5552292A (en) 1993-01-18 1996-09-03 Ikagaku Co., Ltd. Method of screening for colorectal cancer
US5455160A (en) 1993-05-27 1995-10-03 Fagerhol; Magne K. Diagnostic test and kit for disease or disorders in the digestive system
US5681699A (en) 1994-02-11 1997-10-28 Cedars-Sinai Medical Center Methods of diagnosing ulcerative colitis and Crohn's disease
US6174664B1 (en) * 1997-02-05 2001-01-16 University Of Pittsburgh Screening method for inflammatory diseases using neutrophil defensins and lactoferrin
US6358939B1 (en) * 1999-12-21 2002-03-19 Northern Lights Pharmaceuticals, Llc Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease

Also Published As

Publication number Publication date
US20020168698A1 (en) 2002-11-14
EP1340078A2 (de) 2003-09-03
ES2325059T3 (es) 2009-08-25
ATE432470T1 (de) 2009-06-15
EP2071332A1 (de) 2009-06-17
EP1340078B1 (de) 2009-05-27
AU2002902A (en) 2002-05-27
WO2002039883A3 (en) 2002-08-08
US7892762B2 (en) 2011-02-22
US20090253155A1 (en) 2009-10-08
AU2007234504B2 (en) 2010-11-18
CA2427898C (en) 2017-08-15
US7560240B2 (en) 2009-07-14
EP1340078A4 (de) 2006-07-05
WO2002039883A2 (en) 2002-05-23
US7192724B2 (en) 2007-03-20
AU2007234504A1 (en) 2007-12-06
CA2427898A1 (en) 2002-05-23
US20040033537A1 (en) 2004-02-19
AU2002220029B2 (en) 2007-09-06

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