DE60136811D1 - Respiratorische synzytialvirus impfstoffe, welche schützende antigene von promotor-proximalen genen exprimieren - Google Patents
Respiratorische synzytialvirus impfstoffe, welche schützende antigene von promotor-proximalen genen exprimierenInfo
- Publication number
- DE60136811D1 DE60136811D1 DE60136811T DE60136811T DE60136811D1 DE 60136811 D1 DE60136811 D1 DE 60136811D1 DE 60136811 T DE60136811 T DE 60136811T DE 60136811 T DE60136811 T DE 60136811T DE 60136811 D1 DE60136811 D1 DE 60136811D1
- Authority
- DE
- Germany
- Prior art keywords
- gene
- rsv
- genes
- genome
- shifted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18541—Use of virus, viral particle or viral elements as a vector
- C12N2760/18543—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18561—Methods of inactivation or attenuation
- C12N2760/18562—Methods of inactivation or attenuation by genetic engineering
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21370800P | 2000-06-23 | 2000-06-23 | |
PCT/US2001/020107 WO2002000693A2 (en) | 2000-06-23 | 2001-06-22 | Respiratory syncytial virus vaccines expressing protective antigens from promotor-proximal genes |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60136811D1 true DE60136811D1 (de) | 2009-01-15 |
Family
ID=22796187
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60136811T Expired - Lifetime DE60136811D1 (de) | 2000-06-23 | 2001-06-22 | Respiratorische synzytialvirus impfstoffe, welche schützende antigene von promotor-proximalen genen exprimieren |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1294858B1 (de) |
JP (1) | JP2004515218A (de) |
KR (1) | KR100899030B1 (de) |
CN (1) | CN1468301A (de) |
AT (1) | ATE416251T1 (de) |
AU (3) | AU2001268709B2 (de) |
BR (1) | BRPI0112276B8 (de) |
CA (1) | CA2413786A1 (de) |
DE (1) | DE60136811D1 (de) |
ES (1) | ES2317914T3 (de) |
IL (1) | IL153530A0 (de) |
MX (1) | MXPA02012818A (de) |
WO (1) | WO2002000693A2 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100354425C (zh) * | 1999-07-09 | 2007-12-12 | 美国政府健康及人类服务部 | 减毒的人-牛嵌合呼吸道合胞病毒疫苗的生产 |
CA2657955A1 (en) * | 2006-07-27 | 2008-08-07 | Ligocyte Pharmaceuticals, Inc. | Chimeric virus-like particles |
CA2659275C (en) | 2006-07-27 | 2017-01-10 | Ligocyte Pharmaceuticals, Inc. | Chimeric influenza virus-like particles |
CN102753582A (zh) | 2009-11-03 | 2012-10-24 | 莱戈赛特医药股份有限公司 | 嵌合RSV-F多肽、和慢病毒或α-反转录病毒GAG基VLP |
CN105200069A (zh) * | 2015-10-16 | 2015-12-30 | 北京交通大学 | 基于rna聚合酶ⅰ的rsv微型复制基因组及其应用 |
CN108699535B (zh) * | 2015-12-11 | 2023-06-20 | ***合众国- 由健康及人类服务部部长代表 | 包含ns1和ns2基因迁移的重组呼吸道合胞病毒株 |
CN110229219B (zh) * | 2019-06-21 | 2021-03-30 | 中国科学院武汉病毒研究所 | 一种新型的呼吸道合胞病毒疫苗抗原的制备方法及其用途 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998002530A1 (en) * | 1996-07-15 | 1998-01-22 | The Government Of The United States Of America, As Represented By The Department Of Health And Human Services | Production of attenuated respiratory syncytial virus vaccines from cloned nucleotide sequences |
-
2001
- 2001-06-22 AT AT01946696T patent/ATE416251T1/de not_active IP Right Cessation
- 2001-06-22 DE DE60136811T patent/DE60136811D1/de not_active Expired - Lifetime
- 2001-06-22 IL IL15353001A patent/IL153530A0/xx not_active IP Right Cessation
- 2001-06-22 MX MXPA02012818A patent/MXPA02012818A/es active IP Right Grant
- 2001-06-22 JP JP2002505815A patent/JP2004515218A/ja active Pending
- 2001-06-22 AU AU2001268709A patent/AU2001268709B2/en not_active Ceased
- 2001-06-22 KR KR1020027017577A patent/KR100899030B1/ko not_active IP Right Cessation
- 2001-06-22 ES ES01946696T patent/ES2317914T3/es not_active Expired - Lifetime
- 2001-06-22 WO PCT/US2001/020107 patent/WO2002000693A2/en active Application Filing
- 2001-06-22 CA CA002413786A patent/CA2413786A1/en not_active Abandoned
- 2001-06-22 AU AU6870901A patent/AU6870901A/xx active Pending
- 2001-06-22 CN CNA018143628A patent/CN1468301A/zh active Pending
- 2001-06-22 EP EP01946696A patent/EP1294858B1/de not_active Expired - Lifetime
- 2001-06-22 BR BRPI0112276-2 patent/BRPI0112276B8/pt not_active IP Right Cessation
-
2006
- 2006-12-22 AU AU2006252238A patent/AU2006252238A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2006252238A1 (en) | 2007-01-25 |
KR20030045685A (ko) | 2003-06-11 |
ES2317914T3 (es) | 2009-05-01 |
BR0112276A (pt) | 2004-02-10 |
CN1468301A (zh) | 2004-01-14 |
JP2004515218A (ja) | 2004-05-27 |
EP1294858B1 (de) | 2008-12-03 |
KR100899030B1 (ko) | 2009-05-21 |
BRPI0112276B1 (pt) | 2019-12-31 |
IL153530A0 (en) | 2003-07-06 |
WO2002000693A2 (en) | 2002-01-03 |
ATE416251T1 (de) | 2008-12-15 |
AU6870901A (en) | 2002-01-08 |
EP1294858A2 (de) | 2003-03-26 |
WO2002000693A3 (en) | 2002-09-26 |
BRPI0112276B8 (pt) | 2021-05-25 |
CA2413786A1 (en) | 2002-01-03 |
AU2001268709B2 (en) | 2006-09-28 |
MXPA02012818A (es) | 2003-05-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |