DE60135029D1 - Verwendung von löslichen ctla4-mutanten zur behandlung von rheumatoider arthritis - Google Patents

Verwendung von löslichen ctla4-mutanten zur behandlung von rheumatoider arthritis

Info

Publication number
DE60135029D1
DE60135029D1 DE60135029T DE60135029T DE60135029D1 DE 60135029 D1 DE60135029 D1 DE 60135029D1 DE 60135029 T DE60135029 T DE 60135029T DE 60135029 T DE60135029 T DE 60135029T DE 60135029 D1 DE60135029 D1 DE 60135029D1
Authority
DE
Germany
Prior art keywords
treatment
rheumatoid arthritis
soluble ctla4
ctla4 mutants
mutants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60135029T
Other languages
English (en)
Inventor
Robert Cohen
Suzette Carr
David Hagerty
Robert J Peach
Jean-Claude Becker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22804919&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60135029(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DE60135029D1 publication Critical patent/DE60135029D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
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    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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    • A61P35/02—Antineoplastic agents specific for leukemia
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
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  • Public Health (AREA)
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  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
DE60135029T 2000-07-03 2001-07-02 Verwendung von löslichen ctla4-mutanten zur behandlung von rheumatoider arthritis Expired - Lifetime DE60135029D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21591300P 2000-07-03 2000-07-03
PCT/US2001/021204 WO2002002638A2 (en) 2000-07-03 2001-07-02 Methods for treating rheumatic diseases using a soluble ctla4 molecule

Publications (1)

Publication Number Publication Date
DE60135029D1 true DE60135029D1 (de) 2008-09-04

Family

ID=22804919

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60135029T Expired - Lifetime DE60135029D1 (de) 2000-07-03 2001-07-02 Verwendung von löslichen ctla4-mutanten zur behandlung von rheumatoider arthritis

Country Status (39)

Country Link
US (1) US7455835B2 (de)
EP (4) EP1935427B1 (de)
JP (1) JP2004517806A (de)
KR (3) KR100895552B1 (de)
CN (1) CN1318086C (de)
AR (2) AR035037A1 (de)
AT (1) ATE401909T1 (de)
AU (2) AU2001273174B2 (de)
BG (2) BG66024B1 (de)
BR (1) BR0112104A (de)
CA (2) CA2413190C (de)
CY (3) CY1109786T1 (de)
CZ (1) CZ303959B6 (de)
DE (1) DE60135029D1 (de)
DK (2) DK1372696T3 (de)
EE (1) EE05378B1 (de)
ES (2) ES2667203T3 (de)
HK (1) HK1058486A1 (de)
HR (1) HRP20030071B1 (de)
HU (3) HU227669B1 (de)
IL (2) IL153593A0 (de)
IS (1) IS2834B (de)
LT (2) LT1935427T (de)
LV (1) LV12993B (de)
MX (1) MXPA02012603A (de)
MY (1) MY137552A (de)
NO (3) NO20026264L (de)
PE (1) PE20020772A1 (de)
PL (2) PL207534B1 (de)
PT (2) PT1935427T (de)
RS (1) RS50811B (de)
RU (1) RU2287340C2 (de)
SI (3) SI1372696T1 (de)
SK (1) SK287940B6 (de)
TR (1) TR201807700T4 (de)
TW (2) TWI311564B (de)
UY (1) UY26815A1 (de)
WO (1) WO2002002638A2 (de)
ZA (1) ZA200210058B (de)

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