DE60133596D1 - S-Methyl-Dihydro-Ziprasidone für die Behandlung von Schizophrenie - Google Patents

S-Methyl-Dihydro-Ziprasidone für die Behandlung von Schizophrenie

Info

Publication number: DE60133596D1
Authority: DE; Germany
Prior art keywords: ziprasidone; schizophrenia; dihydro; methyl; treatment
Prior art date: 2000-06-02
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60133596T

Other languages

English (en)

Inventor

Chandra A Prakash

Teresa A Smolarek

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Products Inc

Original Assignee

Pfizer Products Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-02

Filing date

2001-05-28

Publication date

2008-05-21

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26903852&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60133596(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-05-28 Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc

2008-05-21 Application granted granted Critical

2008-05-21 Publication of DE60133596D1 publication Critical patent/DE60133596D1/de

2021-05-29 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

NHUDBVVEHOSVCD-UHFFFAOYSA-N 6-chloro-5-[2-[4-(2-methylsulfanylbenzenecarboximidoyl)piperazin-1-yl]ethyl]-1,3-dihydroindol-2-one Chemical compound CSC1=CC=CC=C1C(=N)N1CCN(CCC=2C(=CC=3NC(=O)CC=3C=2)Cl)CC1 NHUDBVVEHOSVCD-UHFFFAOYSA-N 0.000 title 1
201000000980 schizophrenia Diseases 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
Psychiatry (AREA)
Emergency Medicine (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Anesthesiology (AREA)
Psychology (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Hydrogenated Pyridines (AREA)
Medicinal Preparation (AREA)
Plural Heterocyclic Compounds (AREA)

DE60133596T 2000-06-02 2001-05-28 S-Methyl-Dihydro-Ziprasidone für die Behandlung von Schizophrenie Expired - Lifetime DE60133596D1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US20913600P	2000-06-02	2000-06-02
US21217200P	2000-06-16	2000-06-16

Publications (1)

Publication Number	Publication Date
DE60133596D1 true DE60133596D1 (de)	2008-05-21

Family

ID=26903852

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DE60133596T Expired - Lifetime DE60133596D1 (de)	2000-06-02	2001-05-28	S-Methyl-Dihydro-Ziprasidone für die Behandlung von Schizophrenie
DE60124791T Expired - Fee Related DE60124791T2 (de)	2000-06-02	2001-05-28	S-Methyl-Dihydro-Ziprasidone zur Behandlung von psychiatrischen Störungen.
DE60124093T Expired - Lifetime DE60124093D1 (de)	2000-06-02	2001-05-28	S-methyl-dihydro-ziprasidon zur Behandlung von Augenerkrankungen.

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
DE60124791T Expired - Fee Related DE60124791T2 (de)	2000-06-02	2001-05-28	S-Methyl-Dihydro-Ziprasidone zur Behandlung von psychiatrischen Störungen.
DE60124093T Expired - Lifetime DE60124093D1 (de)	2000-06-02	2001-05-28	S-methyl-dihydro-ziprasidon zur Behandlung von Augenerkrankungen.

Country Status (44)

Country	Link
US (1)	US20060287336A1 (de)
EP (3)	EP1698338B1 (de)
JP (2)	JP2003534381A (de)
KR (1)	KR20030007824A (de)
CN (1)	CN1431901A (de)
AP (2)	AP1747A (de)
AR (1)	AR028937A1 (de)
AT (3)	ATE391507T1 (de)
AU (1)	AU2001258690A1 (de)
BG (1)	BG107267A (de)
BR (1)	BR0111271A (de)
CA (1)	CA2410618A1 (de)
CY (1)	CY1105992T1 (de)
CZ (1)	CZ20023860A3 (de)
DE (3)	DE60133596D1 (de)
DK (1)	DK1468686T3 (de)
DO (1)	DOP2001000181A (de)
EA (1)	EA007068B1 (de)
EC (1)	ECSP024369A (de)
EE (1)	EE200200670A (de)
ES (1)	ES2277170T3 (de)
GE (1)	GEP20053512B (de)
HN (1)	HN2001000119A (de)
HR (1)	HRP20020953A2 (de)
HU (1)	HUP0301747A2 (de)
IL (2)	IL152782A0 (de)
IS (1)	IS6619A (de)
MA (1)	MA26908A1 (de)
MX (1)	MXPA02011862A (de)
NO (1)	NO325077B1 (de)
NZ (1)	NZ551012A (de)
OA (1)	OA12267A (de)
PA (1)	PA8518301A1 (de)
PE (1)	PE20011329A1 (de)
PL (1)	PL365576A1 (de)
PT (2)	PT1468686E (de)
SI (1)	SI1468686T1 (de)
SK (1)	SK16622002A3 (de)
SV (1)	SV2002000473A (de)
UA (1)	UA79425C2 (de)
UY (1)	UY26742A1 (de)
WO (1)	WO2001091756A2 (de)
YU (1)	YU90702A (de)
ZA (1)	ZA200209665B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2004054487A2 (en)	2002-12-13	2004-07-01	Regents Of The University Of Minnesota	Scleral depressor
US7667037B2 (en)	2003-10-24	2010-02-23	Teva Pharmaceutical Industries Ltd.	Processes for preparation of ziprasidone
ES2250001B1 (es) *	2004-09-29	2007-06-01	Medichem, S.A.	Proceso para la purificacion de ziprasidona.
JP2012174228A (ja) *	2011-02-24	2012-09-10	Kyocera Corp	プログラム保護装置および通信装置
US10154988B2 (en)	2012-11-14	2018-12-18	The Johns Hopkins University	Methods and compositions for treating schizophrenia
US9981041B2 (en) *	2016-08-23	2018-05-29	Ira Jason Salzman	Ophthalmic lubricating spray

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW491847B (en) *	1996-05-07	2002-06-21	Pfizer	Mesylate dihydrate salts of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2h-indol-2-one
IL126590A (en) *	1996-05-07	2001-11-25	Pfizer	Trihydrate salt of -5 (-2 (-4 (1 (2, 2-benzothiazole - 3yl) -1-piperazinyl) ethyl) - 6-chloro-1, 3-dihydro-2 (1H) - indole - 2On (= Ziprasidone) and pharmaceutical preparations containing it
DE69910706T2 (de) *	1998-05-26	2004-07-08	Pfizer Products Inc., Groton	Medikament zur Behandlung von Glaukoma und ischämischer Retinopathie
EP1165083A2 (de) *	1999-04-06	2002-01-02	Sepracor Inc.	Methoden und zusammenstellungen zur behandlung von psychosen und damit zusammenhängenden erkrankungen unter verwendung von ziprasidonmetaboliten

2001
- 2001-05-28 EP EP06116051A patent/EP1698338B1/de not_active Expired - Lifetime
- 2001-05-28 EP EP01932011A patent/EP1286672B1/de not_active Expired - Lifetime
- 2001-05-28 NZ NZ551012A patent/NZ551012A/en unknown
- 2001-05-28 AU AU2001258690A patent/AU2001258690A1/en not_active Abandoned
- 2001-05-28 YU YU90702A patent/YU90702A/sh unknown
- 2001-05-28 PL PL01365576A patent/PL365576A1/xx unknown
- 2001-05-28 SI SI200130681T patent/SI1468686T1/sl unknown
- 2001-05-28 BR BR0111271-6A patent/BR0111271A/pt not_active Application Discontinuation
- 2001-05-28 AT AT06116051T patent/ATE391507T1/de not_active IP Right Cessation
- 2001-05-28 GE GE4972A patent/GEP20053512B/en unknown
- 2001-05-28 CA CA002410618A patent/CA2410618A1/en not_active Abandoned
- 2001-05-28 EE EEP200200670A patent/EE200200670A/xx unknown
- 2001-05-28 JP JP2001587771A patent/JP2003534381A/ja not_active Withdrawn
- 2001-05-28 SK SK1662-2002A patent/SK16622002A3/sk not_active Application Discontinuation
- 2001-05-28 ES ES04013380T patent/ES2277170T3/es not_active Expired - Lifetime
- 2001-05-28 OA OA1200200349A patent/OA12267A/en unknown
- 2001-05-28 CN CN01810620A patent/CN1431901A/zh active Pending
- 2001-05-28 IL IL15278201A patent/IL152782A0/xx active IP Right Grant
- 2001-05-28 DE DE60133596T patent/DE60133596D1/de not_active Expired - Lifetime
- 2001-05-28 PT PT04013380T patent/PT1468686E/pt unknown
- 2001-05-28 MX MXPA02011862A patent/MXPA02011862A/es active IP Right Grant
- 2001-05-28 EP EP04013380A patent/EP1468686B1/de not_active Expired - Lifetime
- 2001-05-28 DK DK04013380T patent/DK1468686T3/da active
- 2001-05-28 CZ CZ20023860A patent/CZ20023860A3/cs unknown
- 2001-05-28 HU HU0301747A patent/HUP0301747A2/hu unknown
- 2001-05-28 WO PCT/IB2001/000933 patent/WO2001091756A2/en active IP Right Grant
- 2001-05-28 AT AT04013380T patent/ATE345818T1/de not_active IP Right Cessation
- 2001-05-28 KR KR1020027016364A patent/KR20030007824A/ko not_active Application Discontinuation
- 2001-05-28 AT AT01932011T patent/ATE343387T1/de not_active IP Right Cessation
- 2001-05-28 UA UA2002119557A patent/UA79425C2/uk unknown
- 2001-05-28 DE DE60124791T patent/DE60124791T2/de not_active Expired - Fee Related
- 2001-05-28 PT PT06116051T patent/PT1698338E/pt unknown
- 2001-05-28 DE DE60124093T patent/DE60124093D1/de not_active Expired - Lifetime
- 2001-05-28 EA EA200201168A patent/EA007068B1/ru not_active IP Right Cessation
- 2001-05-31 PE PE2001000504A patent/PE20011329A1/es not_active Application Discontinuation
- 2001-05-31 UY UY26742A patent/UY26742A1/es not_active Application Discontinuation
- 2001-05-31 AP AP2005003272A patent/AP1747A/xx active
- 2001-05-31 DO DO2001000181A patent/DOP2001000181A/es unknown
- 2001-05-31 AP APAP/P/2001/002180A patent/AP1831A/en active
- 2001-05-31 HN HN2001000119A patent/HN2001000119A/es unknown
- 2001-06-01 PA PA20018518301A patent/PA8518301A1/es unknown
- 2001-06-01 AR ARP010102641A patent/AR028937A1/es unknown
- 2001-06-01 SV SV2001000473A patent/SV2002000473A/es not_active Application Discontinuation
- 2001-06-04 US US09/873,973 patent/US20060287336A1/en not_active Abandoned
2002
- 2002-11-11 IL IL152782A patent/IL152782A/en not_active IP Right Cessation
- 2002-11-12 BG BG107267A patent/BG107267A/bg unknown
- 2002-11-14 IS IS6619A patent/IS6619A/is unknown
- 2002-11-28 ZA ZA200209665A patent/ZA200209665B/en unknown
- 2002-11-29 EC EC2002004369A patent/ECSP024369A/es unknown
- 2002-11-29 MA MA26927A patent/MA26908A1/fr unknown
- 2002-11-29 NO NO20025760A patent/NO325077B1/no unknown
- 2002-12-02 HR HR20020953A patent/HRP20020953A2/hr not_active Application Discontinuation
2007
- 2007-02-08 CY CY20071100161T patent/CY1105992T1/el unknown
- 2007-11-14 JP JP2007296039A patent/JP2008056700A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
SV2002000473A (es)	2002-10-24
JP2003534381A (ja)	2003-11-18
DE60124093D1 (de)	2006-12-07
AU2001258690A1 (en)	2001-12-11
ECSP024369A (es)	2003-02-06
BG107267A (bg)	2003-06-30
EP1286672A2 (de)	2003-03-05
GEP20053512B (en)	2005-05-10
PT1468686E (pt)	2007-01-31
EP1468686B1 (de)	2006-11-22
DE60124791D1 (de)	2007-01-04
EP1286672B1 (de)	2006-10-25
US20060287336A1 (en)	2006-12-21
YU90702A (sh)	2005-11-28
DK1468686T3 (da)	2007-03-12
JP2008056700A (ja)	2008-03-13
HRP20020953A2 (en)	2005-02-28
ATE343387T1 (de)	2006-11-15
NO20025760D0 (no)	2002-11-29
UY26742A1 (es)	2001-12-28
EP1468686A3 (de)	2004-12-01
IS6619A (is)	2002-11-14
NZ551012A (en)	2008-04-30
HUP0301747A2 (hu)	2003-09-29
AP1831A (en)	2008-02-26
IL152782A0 (en)	2003-06-24
CA2410618A1 (en)	2001-12-06
OA12267A (en)	2004-01-20
MA26908A1 (fr)	2004-12-20
AR028937A1 (es)	2003-05-28
SK16622002A3 (sk)	2004-07-07
AP2005003272A0 (en)	2005-03-31
PE20011329A1 (es)	2002-01-15
WO2001091756A3 (en)	2002-09-26
ATE345818T1 (de)	2006-12-15
CY1105992T1 (el)	2011-04-06
EP1698338B1 (de)	2008-04-09
WO2001091756A2 (en)	2001-12-06
CN1431901A (zh)	2003-07-23
EA007068B1 (ru)	2006-06-30
BR0111271A (pt)	2003-06-10
NO325077B1 (no)	2008-01-28
ATE391507T1 (de)	2008-04-15
ES2277170T3 (es)	2007-07-01
AP1747A (en)	2007-05-31
EP1698338A2 (de)	2006-09-06
UA79425C2 (en)	2007-06-25
HN2001000119A (es)	2001-09-11
SI1468686T1 (sl)	2007-04-30
PA8518301A1 (es)	2002-09-17
IL152782A (en)	2007-10-31
PT1698338E (pt)	2008-06-03
EP1468686A2 (de)	2004-10-20
DOP2001000181A (es)	2002-04-15
CZ20023860A3 (cs)	2004-01-14
DE60124791T2 (de)	2007-09-13
ZA200209665B (en)	2003-11-28
EE200200670A (et)	2004-08-16
EP1698338A3 (de)	2006-09-20
PL365576A1 (en)	2005-01-10
KR20030007824A (ko)	2003-01-23
NO20025760L (no)	2003-01-15
MXPA02011862A (es)	2003-04-10
EA200201168A1 (ru)	2003-06-26

Legal Events

Date	Code	Title	Description
2009-01-02	8332	No legal effect for de

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ATE418554T1 (de)	2009-01-15	1-acyl-pyrrolidin-derivate für die behandlung von viralen infektionen
DE69927823T2 (de)	2006-06-14	Hydrogel für die therapeutische behandlung von aneurysmas
ATE374196T1 (de)	2007-10-15	Dihydrobenzodiazepin-2-on-derivative für die behandlung von neurologischen erkrankungen
ATE441417T1 (de)	2009-09-15	Benzoädüazepinderivate für die behandlung von neurologischen krankheiten
DE60233414D1 (de)	2009-10-01	Kombinationen für die behandlung entzündlicher erkrankungen
ATE312117T1 (de)	2005-12-15	Verbindungen für die behandlung von ischämie
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ATE276262T1 (de)	2004-10-15	Oxazinochinolone für die behandlung viraler infektionen
ATE254913T1 (de)	2003-12-15	Diacerein zur behandlung von psoriasis
DE50105735D1 (de)	2005-04-28	Chlorzoxazon zur behandlung von psoriasis
DE60103685D1 (de)	2004-07-15	Behandlung von Poriomania
DE60133596D1 (de)	2008-05-21	S-Methyl-Dihydro-Ziprasidone für die Behandlung von Schizophrenie
ATE230741T1 (de)	2003-01-15	3-tetrahydropyridin-4-yl-indole zur behandlung von psychotischen störungen