DE60114996D1 - Senkung des serum cholesterols - Google Patents
Senkung des serum cholesterolsInfo
- Publication number
- DE60114996D1 DE60114996D1 DE60114996T DE60114996T DE60114996D1 DE 60114996 D1 DE60114996 D1 DE 60114996D1 DE 60114996 T DE60114996 T DE 60114996T DE 60114996 T DE60114996 T DE 60114996T DE 60114996 D1 DE60114996 D1 DE 60114996D1
- Authority
- DE
- Germany
- Prior art keywords
- lowering
- serum cholesterol
- subject
- cholesterol
- glp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Revoked
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200000375 | 2000-03-08 | ||
DK200000375 | 2000-03-08 | ||
PCT/DK2001/000150 WO2001066135A1 (en) | 2000-03-08 | 2001-03-08 | Lowering serum lipids |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60114996D1 true DE60114996D1 (de) | 2005-12-22 |
DE60114996T2 DE60114996T2 (de) | 2006-08-10 |
Family
ID=8159299
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60114996T Revoked DE60114996T2 (de) | 2000-03-08 | 2001-03-08 | Senkung des serum cholesterols |
Country Status (7)
Country | Link |
---|---|
EP (2) | EP1263458B1 (de) |
JP (1) | JP2003525908A (de) |
AT (1) | ATE309818T1 (de) |
AU (1) | AU2001237254A1 (de) |
DE (1) | DE60114996T2 (de) |
ES (1) | ES2253353T3 (de) |
WO (1) | WO2001066135A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU6323001A (en) | 2000-05-19 | 2001-12-03 | Bionebraska Inc | Treatment of acute coronary syndrome with glp-1 |
PL205971B1 (pl) | 2001-09-24 | 2010-06-30 | Imp Innovations Ltd | Zastosowanie PYY₃-₃₆ do wytwarzania leku na ograniczanie apetytu, zmniejszenie otyłości lub do zapobiegania otyłości |
WO2003059378A2 (en) | 2001-12-29 | 2003-07-24 | Novo Nordisk A/S | Combined use of a glp-1 compound and another drug for treating dyslipidemia |
ES2280596T3 (es) * | 2001-12-29 | 2007-09-16 | Novo Nordisk A/S | Uso combinado de un compuesto de glp-1 y un inhibidor de una aldosa reductasa. |
WO2003057235A2 (en) | 2002-01-10 | 2003-07-17 | Imperial College Innovations Ltd | Modification of feeding behavior |
JP2005535569A (ja) * | 2002-04-04 | 2005-11-24 | ノボ・ノルデイスク・エー/エス | Glp−1アゴニスト及び心臓血管合併症 |
EP1688148A1 (de) * | 2002-12-03 | 2006-08-09 | Novo Nordisk A/S | Behandlung mit Kombinationspräparaten aus Exendin-4 und Thiazolidindionen |
WO2004050115A2 (en) * | 2002-12-03 | 2004-06-17 | Novo Nordisk A/S | Combination treatment using exendin-4 and thiazolidinediones |
GB0300571D0 (en) | 2003-01-10 | 2003-02-12 | Imp College Innovations Ltd | Modification of feeding behaviour |
US20060228331A1 (en) | 2003-10-10 | 2006-10-12 | Novo Nordisk A/S | IL-21 Derivatives and variants |
ES2336575T3 (es) | 2005-09-22 | 2010-04-14 | Biocompatibles Uk Limited | Polipeptidos de fusion glp-1 (peptido-1 similar al glucagon) con resistencia aumentada a la peptidasa. |
ATE444741T1 (de) | 2006-05-10 | 2009-10-15 | Biocompatibles Uk Ltd | Glp-1 peptide enthaltende kugelförmige mikrokapseln, deren produktion und deren verwendung |
EP2452683A3 (de) | 2006-06-26 | 2012-08-22 | Amgen Inc. | Verfahren zur Behandlung von Atherosklerose |
WO2008019143A2 (en) * | 2006-08-04 | 2008-02-14 | Amylin Pharmaceuticals, Inc | Use of exendins and glp-i receptor agonists for altering lipoprotein particle size and subclass composition |
TWI428346B (zh) | 2006-12-13 | 2014-03-01 | Imp Innovations Ltd | 新穎化合物及其等對進食行為影響 |
TW200843794A (en) * | 2006-12-21 | 2008-11-16 | Centocor Inc | Use of long-acting GLP-1 receptor agonists to improve insulin sensitivity and lipid profiles |
EP2163243A1 (de) * | 2008-09-12 | 2010-03-17 | Biocompatibles UK Limited | Behandlung akuter Herzinfarkte mithilfe eingekapselter Zellen, welche GLP-1-Peptide oder deren Analoga kodieren und absondern |
EP2664374A1 (de) * | 2012-05-15 | 2013-11-20 | F. Hoffmann-La Roche AG | Lysinglutaminsäuredipeptidderivate |
Family Cites Families (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE110083T1 (de) | 1986-05-05 | 1994-09-15 | Gen Hospital Corp | Insulinotropes hormon. |
NZ222907A (en) | 1986-12-16 | 1990-08-28 | Novo Industri As | Preparation for intranasal administration containing a phospholipid absorption enhancing system |
DE68929217T2 (de) | 1989-03-20 | 2000-11-30 | Gen Hospital Corp | Insulinotropes hormon |
EP0512042B1 (de) | 1990-01-24 | 1998-04-08 | BUCKLEY, Douglas I. | Glp-1-analoga verwendbar in der diabetesbehandlung |
DK36392D0 (da) * | 1992-03-19 | 1992-03-19 | Novo Nordisk As | Anvendelse af kemisk forbindelse |
DK36492D0 (da) | 1992-03-19 | 1992-03-19 | Novo Nordisk As | Praeparat |
DK39892D0 (da) | 1992-03-25 | 1992-03-25 | Bernard Thorens | Peptid |
US5424286A (en) | 1993-05-24 | 1995-06-13 | Eng; John | Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same |
US5574008A (en) | 1994-08-30 | 1996-11-12 | Eli Lilly And Company | Biologically active fragments of glucagon-like insulinotropic peptide |
US5512549A (en) | 1994-10-18 | 1996-04-30 | Eli Lilly And Company | Glucagon-like insulinotropic peptide analogs, compositions, and methods of use |
CN1183158C (zh) | 1996-06-05 | 2005-01-05 | 罗赫诊断器材股份有限公司 | Exendin类似物,其制备方法及含有它们的药物制剂 |
US5885997A (en) | 1996-07-01 | 1999-03-23 | Dr. Reddy's Research Foundation | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases |
CN1221417A (zh) | 1996-07-26 | 1999-06-30 | 雷迪博士研究基金会 | 具有抗糖尿病、降低血脂、抗高血压性能的噻唑烷二酮化合物,其制备方法及其药物组合物 |
CA2468374C (en) | 1996-08-30 | 2010-12-21 | Novo-Nordisk A/S | Glp-1 derivatives |
CN1190434C (zh) | 1996-12-31 | 2005-02-23 | 雷迪实验室有限公司 | 新的杂环化合物、其制备方法和含有它们的药物组合物及其在治疗糖尿病和相关疾病中的应用 |
DE122007000044I2 (de) * | 1997-01-07 | 2011-05-05 | Amylin Pharmaceuticals Inc | Verwendung von exedinen und deren antagonisten zur verminderung der lebensmittelaufnahme |
WO1998043658A1 (en) | 1997-03-31 | 1998-10-08 | Eli Lilly And Company | Glucagon-like peptide-1 analogs |
WO1997041119A1 (en) | 1997-05-02 | 1997-11-06 | Dr. Reddy's Research Foundation | Novel antidiabetic compounds having hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
US6440961B1 (en) | 1997-10-27 | 2002-08-27 | Dr. Reddy's Research Foundation | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them |
WO1999019313A1 (en) | 1997-10-27 | 1999-04-22 | Dr. Reddy's Research Foundation | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them |
CN100376560C (zh) | 1997-10-27 | 2008-03-26 | 雷迪实验室有限公司 | 新型三环化合物和其作为药物的用途;其制备方法和包含该化合物的药物组合物 |
AU6966498A (en) | 1997-12-02 | 1998-10-30 | Dr. Reddy's Research Foundation | Thiazolidinedione and oxazolidinedione derivatives having antidiabetic, hypol ipidaemic and antihypertensive properties |
US6803357B1 (en) * | 1998-02-02 | 2004-10-12 | New England Medical Center Hospitals, Inc. | Method of regulating glucose metabolism, and reagents related thereto |
EP1060191B1 (de) | 1998-02-27 | 2010-04-28 | Novo Nordisk A/S | Abkömmlinge von glp-1 analogen |
AU3247799A (en) | 1998-02-27 | 1999-09-15 | Novo Nordisk A/S | Glp-1 derivatives of glp-1 and exendin with protracted profile of action |
WO1999043707A1 (en) | 1998-02-27 | 1999-09-02 | Novo Nordisk A/S | N-terminally modified glp-1 derivatives |
WO1999043341A1 (en) | 1998-02-27 | 1999-09-02 | Novo Nordisk A/S | Glp-1 derivatives with helix-content exceeding 25 %, forming partially structured micellar-like aggregates |
EP1056774A1 (de) | 1998-02-27 | 2000-12-06 | Novo Nordisk A/S | N-terminal verkürzte glp-1 derivate |
AU6325599A (en) | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
AU6325899A (en) | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
EP1123268A1 (de) | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | Neuartige vebindungen, ihre herstellung und ihre verwendung |
JP2002527507A (ja) | 1998-10-21 | 2002-08-27 | ノボ ノルディスク アクティーゼルスカブ | 新規化合物類、それらの調製及び使用 |
AU6325799A (en) | 1998-10-21 | 2000-05-08 | Dr. Reddy's Research Foundation | New compounds, their preparation and use |
EP1123267A1 (de) | 1998-10-21 | 2001-08-16 | Novo Nordisk A/S | Neuartige vebindungen, ihre herstellung und ihre verwendung |
WO2000041121A1 (en) | 1999-01-07 | 2000-07-13 | Ccrewards.Com | Method and arrangement for issuance and management of digital coupons and sales offers |
BR0010683A (pt) | 1999-04-16 | 2003-07-01 | Reddy Research Foundation | Formas polimórficas de um agente antidiabético: processo para seu preparo e composições farmacêuticas contendo o mesmo |
WO2000063191A1 (en) | 1999-04-16 | 2000-10-26 | Dr. Reddy's Research Foundation | Novel polymorphic forms of an antidiabetic agent: process for their preparation and a pharmaceutical composition containing them |
WO2000063193A1 (en) | 1999-04-16 | 2000-10-26 | Dr. Reddy's Research Foundation | Novel polymorphic forms of an antidiabetic agent: process for their preparation and a pharmaceutical composition containing them |
WO2000063153A1 (en) | 1999-04-20 | 2000-10-26 | Novo Nordisk A/S | New compounds, their preparation and use |
WO2000063196A1 (en) | 1999-04-20 | 2000-10-26 | Novo Nordisk A/S | New compounds, their preparation and use |
AU3957900A (en) | 1999-04-20 | 2000-11-02 | Novo Nordisk A/S | New compounds, their preparation and use |
EP1171438A1 (de) | 1999-04-20 | 2002-01-16 | Novo Nordisk A/S | Verbindungen, ihre herstellung und ihre verwendung |
CN1372570A (zh) * | 1999-04-30 | 2002-10-02 | 安米林药品公司 | 修饰的exendin和exendin激动剂 |
AU1269501A (en) * | 1999-11-12 | 2001-05-30 | Novo Nordisk A/S | Use of glp-1 agonists for the inhibition of beta cell degeneration |
DE60105547T3 (de) * | 2000-01-10 | 2014-12-31 | Amylin Pharmaceuticals, Llc | Verwendung von exendinen und deren agonisten zur behandlung von hypertriglyceridämie |
-
2001
- 2001-03-08 EP EP01909571A patent/EP1263458B1/de not_active Revoked
- 2001-03-08 JP JP2001564787A patent/JP2003525908A/ja active Pending
- 2001-03-08 WO PCT/DK2001/000150 patent/WO2001066135A1/en active IP Right Grant
- 2001-03-08 AT AT01909571T patent/ATE309818T1/de not_active IP Right Cessation
- 2001-03-08 ES ES01909571T patent/ES2253353T3/es not_active Expired - Lifetime
- 2001-03-08 AU AU2001237254A patent/AU2001237254A1/en not_active Abandoned
- 2001-03-08 DE DE60114996T patent/DE60114996T2/de not_active Revoked
- 2001-03-08 EP EP05110709A patent/EP1634605A3/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
DE60114996T2 (de) | 2006-08-10 |
ATE309818T1 (de) | 2005-12-15 |
EP1634605A3 (de) | 2006-10-11 |
ES2253353T3 (es) | 2006-06-01 |
AU2001237254A1 (en) | 2001-09-17 |
EP1634605A2 (de) | 2006-03-15 |
EP1263458B1 (de) | 2005-11-16 |
JP2003525908A (ja) | 2003-09-02 |
WO2001066135A1 (en) | 2001-09-13 |
EP1263458A1 (de) | 2002-12-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8331 | Complete revocation |