DE60112607T2 - 3-arylindolderivate und deren verwendung als cb2-rezeptoragonisten - Google Patents

3-arylindolderivate und deren verwendung als cb2-rezeptoragonisten Download PDF

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Publication number
DE60112607T2
DE60112607T2 DE60112607T DE60112607T DE60112607T2 DE 60112607 T2 DE60112607 T2 DE 60112607T2 DE 60112607 T DE60112607 T DE 60112607T DE 60112607 T DE60112607 T DE 60112607T DE 60112607 T2 DE60112607 T2 DE 60112607T2
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Prior art keywords
receptor agonists
arylindole derivatives
arylindole
derivatives
agonists
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Expired - Lifetime
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DE60112607T
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DE60112607D1 (de
Inventor
Francis Barth
Christian Congy
Carole Guillaumont
Murielle Rinaldi
Fabienne Vasse
Claude Vernhet
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Sanofi Aventis France
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Sanofi Aventis France
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
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    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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DE60112607T 2000-11-22 2001-11-21 3-arylindolderivate und deren verwendung als cb2-rezeptoragonisten Expired - Lifetime DE60112607T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0015158A FR2816938B1 (fr) 2000-11-22 2000-11-22 Derives de 3-aroylindole, leur procede de preparation et les compositions pharmaceutiques en contenant
PCT/FR2001/003665 WO2002042269A1 (fr) 2000-11-22 2001-11-21 Derives de 3-aroylindole et leur utilisation en tant qu'agonistes des recepteurs cb2

Publications (2)

Publication Number Publication Date
DE60112607D1 DE60112607D1 (de) 2005-09-15
DE60112607T2 true DE60112607T2 (de) 2006-06-14

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DE60112607T Expired - Lifetime DE60112607T2 (de) 2000-11-22 2001-11-21 3-arylindolderivate und deren verwendung als cb2-rezeptoragonisten

Country Status (32)

Country Link
US (1) US6995184B2 (de)
EP (1) EP1339679B1 (de)
JP (1) JP4264258B2 (de)
KR (1) KR20030048161A (de)
CN (1) CN1234688C (de)
AR (1) AR033594A1 (de)
AT (1) ATE301638T1 (de)
AU (1) AU2002222001A1 (de)
BG (1) BG107827A (de)
BR (1) BR0115580A (de)
CA (1) CA2427444A1 (de)
CZ (1) CZ20031392A3 (de)
DE (1) DE60112607T2 (de)
DK (1) DK1339679T3 (de)
DZ (1) DZ3443A1 (de)
EA (1) EA005854B1 (de)
EE (1) EE200300244A (de)
ES (1) ES2247201T3 (de)
FR (1) FR2816938B1 (de)
HR (1) HRP20030417A2 (de)
HU (1) HUP0400561A2 (de)
IL (1) IL155634A0 (de)
IS (1) IS6802A (de)
MA (1) MA26959A1 (de)
MX (1) MXPA03004549A (de)
NO (1) NO20031952L (de)
NZ (1) NZ525609A (de)
PL (1) PL362276A1 (de)
SK (1) SK6042003A3 (de)
TW (1) TWI224592B (de)
WO (1) WO2002042269A1 (de)
ZA (1) ZA200303728B (de)

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JP2006517194A (ja) 2002-06-06 2006-07-20 イッサム リサーチ ディベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティ オブ エルサレム 骨成長を調節するための方法、組成物および製造物
ATE375349T1 (de) 2002-08-02 2007-10-15 Merck & Co Inc Substituierte furo(2,3-b)pyridin derivate
FR2843964B1 (fr) * 2002-08-29 2004-10-01 Sanofi Synthelabo Derives de dioxane-2-alkylcarbamates, leur preparation et leur application en therapeutique
FR2847899B1 (fr) * 2002-11-29 2006-04-28 Sanofi Synthelabo Derives d'indole-3-carboxamide, leur preparation et leur application en therapeutique
FR2854633B1 (fr) * 2003-05-07 2005-06-24 Sanofi Synthelabo Derives de piperidinyl-et piperazinyl-alkylcarbamates, leur preparation et leur application en therapeutique
FR2856684B1 (fr) 2003-06-26 2008-04-11 Sanofi Synthelabo Derives de diphenylpyridine, leur preparation et leur application en therapeutique
FR2865205B1 (fr) 2004-01-16 2006-02-24 Sanofi Synthelabo Derives de type aryloxyalkylcarbamates, leur preparation et leur application en therapeutique
CA2571679A1 (en) * 2004-06-22 2005-12-29 Pharmos Limited Use of cb2 receptors agonists for the treatment of huntington's disease
KR20070041717A (ko) 2004-07-12 2007-04-19 카딜라 핼쓰캐어 리미티드 카나비노이드 수용체 조절자인 트리시클릭 피라졸 유도체들
US20060025448A1 (en) 2004-07-22 2006-02-02 Cadila Healthcare Limited Hair growth stimulators
CA2587210A1 (en) * 2004-11-22 2006-06-01 Threshold Pharmaceuticals, Inc. Tubulin binding anti cancer agents and prodrugs thereof
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FR2893615B1 (fr) 2005-11-18 2008-03-07 Sanofi Aventis Sa Derives de 3-acylindole, leur preparation et leur application en therapeutique
CA2647598A1 (en) * 2006-05-31 2007-12-06 Abbott Laboratories Compounds as cannabinoid receptor ligands and uses thereof
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US7872033B2 (en) 2007-04-17 2011-01-18 Abbott Laboratories Compounds as cannabinoid receptor ligands
FR2915199B1 (fr) * 2007-04-18 2010-01-22 Sanofi Aventis Derives de triazolopyridine-carboxamides et triazolopyrimidine-carboxamides, leur preparation et leur application en therapeutique.
CN101711253A (zh) * 2007-05-18 2010-05-19 雅培制药有限公司 用作***素受体配体的新化合物
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FR2933697B1 (fr) * 2008-07-11 2010-08-13 Sanofi Aventis Derives de 1-benzyl-cinnolin-4-(1h)-one substitues, leur preparation et leur application en therapeutique
US8846730B2 (en) * 2008-09-08 2014-09-30 Abbvie Inc. Compounds as cannabinoid receptor ligands
EP2428507B1 (de) * 2008-09-16 2015-10-21 AbbVie Bahamas Ltd. Cannabinoid-Rezeptorliganden
PA8854001A1 (es) * 2008-12-16 2010-07-27 Abbott Lab Compuestos novedosos como ligandos de receptores de canabinoides
FR2941696B1 (fr) 2009-02-05 2011-04-15 Sanofi Aventis Derives d'azaspiranyl-alkylcarbamates d'heterocycles a 5 chainons, leur preparation et leur application en therapeutique
FR2945533B1 (fr) 2009-05-12 2011-05-27 Sanofi Aventis Derives de cyclopenta°c!pyrrolyl-alkylcarbamates d'heterocycles a 5 chainons, leur preparation et leur application en therapeutique
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ATE301638T1 (de) 2005-08-15
KR20030048161A (ko) 2003-06-18
CN1483023A (zh) 2004-03-17
DZ3443A1 (fr) 2002-05-30
FR2816938B1 (fr) 2003-01-03
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EA005854B1 (ru) 2005-06-30
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PL362276A1 (en) 2004-10-18
IL155634A0 (en) 2003-11-23
FR2816938A1 (fr) 2002-05-24
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DE60112607D1 (de) 2005-09-15
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