DE60031357D1 - Testtablett, Kit und Verfahren zum Screening von Körperflüssigkeiten von Neugeborenen durch Tandem-Massenspektrometrie - Google Patents

Testtablett, Kit und Verfahren zum Screening von Körperflüssigkeiten von Neugeborenen durch Tandem-Massenspektrometrie

Info

Publication number
DE60031357D1
DE60031357D1 DE60031357T DE60031357T DE60031357D1 DE 60031357 D1 DE60031357 D1 DE 60031357D1 DE 60031357 T DE60031357 T DE 60031357T DE 60031357 T DE60031357 T DE 60031357T DE 60031357 D1 DE60031357 D1 DE 60031357D1
Authority
DE
Germany
Prior art keywords
kit
mass spectrometry
tandem mass
body fluids
test tray
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60031357T
Other languages
English (en)
Other versions
DE60031357T2 (de
Inventor
Jan Ostrup
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PerkinElmer Health Sciences Inc
Original Assignee
PerkinElmer Life Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PerkinElmer Life Sciences Inc filed Critical PerkinElmer Life Sciences Inc
Publication of DE60031357D1 publication Critical patent/DE60031357D1/de
Application granted granted Critical
Publication of DE60031357T2 publication Critical patent/DE60031357T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N2001/2893—Preparing calibration standards
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
DE60031357T 1999-12-29 2000-05-29 Geräte, Kits und Verfahren zum Testen von Körperflüssigkeiten zum Screening vonNeugeborenen durch Tandem-Massenspektrometrie-Kits Expired - Lifetime DE60031357T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US474604 1983-03-11
US47460499A 1999-12-29 1999-12-29

Publications (2)

Publication Number Publication Date
DE60031357D1 true DE60031357D1 (de) 2006-11-30
DE60031357T2 DE60031357T2 (de) 2007-08-30

Family

ID=23884258

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60031357T Expired - Lifetime DE60031357T2 (de) 1999-12-29 2000-05-29 Geräte, Kits und Verfahren zum Testen von Körperflüssigkeiten zum Screening vonNeugeborenen durch Tandem-Massenspektrometrie-Kits

Country Status (4)

Country Link
US (1) US20030199102A1 (de)
EP (1) EP1113269B1 (de)
AT (1) ATE343130T1 (de)
DE (1) DE60031357T2 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7297545B2 (en) * 1999-01-30 2007-11-20 Pediatrix Screening, Inc. Clinical method for the genetic screening of newborns using tandem mass spectrometry and internal standards therefor
US6800489B2 (en) * 2002-06-05 2004-10-05 Izaak Walton Killam Health Center Electrospray tandem mass spectrometry of transition metal diimine complexes of amino acids, α-hydroxyketones and hexose phosphates for newborn screening
US20050048499A1 (en) * 2003-08-29 2005-03-03 Perkin Elmer Life Sciences, Inc. Tandem mass spectrometry method for the genetic screening of inborn errors of metabolism in newborns
US7485435B2 (en) * 2004-08-30 2009-02-03 Perkinelmer Las, Inc. Simultaneous detection of metabolic enzyme activity and metabolite levels
EP1664721A4 (de) * 2003-09-22 2008-05-21 Becton Dickinson Co Quantifizierung von analyten unter verwendung innerer standards
ES2452025T3 (es) * 2005-06-30 2014-03-31 Biocrates Life Sciences Ag Aparato de análisis de un perfil de metabolitos
CN101484808B (zh) * 2006-05-05 2015-11-25 珀金埃尔默·拉斯公司 用质谱法定量分析源自表面的样品
AU2010241614B2 (en) * 2009-04-30 2014-09-04 Purdue Research Foundation Ion generation using wetted porous material
US9500572B2 (en) 2009-04-30 2016-11-22 Purdue Research Foundation Sample dispenser including an internal standard and methods of use thereof
MX347230B (es) * 2011-03-04 2017-04-20 Becton Dickinson Co Dispositivo para extracción de sangre que contiene inhibidor de lisofosfolipasa.
US9074237B2 (en) 2011-04-13 2015-07-07 Stc.Unm Method for diagnosing Francisella tularensis infection
EP2783388A4 (de) * 2011-11-23 2015-12-09 Quest Diagnostics Invest Inc Kisspeptin-54 nachweis durch tandem-massenspektrometrie
EP2671642B1 (de) * 2012-06-04 2016-12-28 Michael Böttcher Verfahren zum Bestimmen des Gehalts einer nachzuweisenden Substanz in einer Probe
CN108287209B (zh) 2013-01-31 2021-01-26 普度研究基金会 分析原油的方法
US10008375B2 (en) 2013-01-31 2018-06-26 Purdue Research Foundation Systems and methods for analyzing an extracted sample
US9620344B2 (en) 2013-06-25 2017-04-11 Purdue Research Foundation Mass spectrometry analysis of microorganisms in samples
JP2017101924A (ja) * 2014-03-31 2017-06-08 積水メディカル株式会社 内部標準物質試薬
US20170189902A1 (en) * 2014-09-12 2017-07-06 Pinpoint Testing, Llc Ready-to-constitute analytical platforms for chemical analyses and quantification
US9786478B2 (en) 2014-12-05 2017-10-10 Purdue Research Foundation Zero voltage mass spectrometry probes and systems
EP4379770A2 (de) 2015-02-06 2024-06-05 Purdue Research Foundation Sonden, systeme und kartuschen
CN108152380A (zh) * 2016-12-05 2018-06-12 山东国际生物科技园发展有限公司 串联质谱非衍生化法多种氨基酸和肉碱检测试剂盒
US10793327B2 (en) 2017-10-09 2020-10-06 Terumo Bct Biotechnologies, Llc Lyophilization container and method of using same
CN110220984A (zh) * 2018-03-01 2019-09-10 上海可力梅塔生物医药科技有限公司 一种衍生化法检测试剂盒
CN114127501B (zh) 2019-03-14 2023-02-17 泰尔茂比司特生物技术有限公司 多部分冻干容器及使用方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3607072A (en) * 1970-01-21 1971-09-21 Mendel Friedman Novel cysteine derivative
US3791933A (en) * 1971-02-25 1974-02-12 Geomet Rapid methods for assay of enzyme substrates and metabolites
US3966852A (en) * 1971-10-28 1976-06-29 Siemens Aktiengesellschaft Method for preparing test specimens for analysis
JPS6110772A (ja) * 1984-06-26 1986-01-18 Kyowa Medetsukusu Kk 生体成分の分析法
US4714682A (en) * 1985-12-11 1987-12-22 Flow Cytometry Standards Corporation Fluorescent calibration microbeads simulating stained cells
US5759774A (en) * 1988-05-18 1998-06-02 Cobe Laboratories, Inc. Method of detecting circulating antibody types using dried or lyophilized cells
US5183761A (en) * 1989-07-21 1993-02-02 Freeman Mary J Method of making calibration solution for verifying calibration and linearity of vertical photometers
US5031449A (en) * 1990-03-02 1991-07-16 Shimadzu Corporation Electrochemical detector for liquid chromatographic analysis of carbohydrates
US5212096A (en) * 1992-02-19 1993-05-18 University Of Colorado Foundation, Inc. Gas chromatography/mass spectrometry determination of ascorbate and oxidation products thereof
JP2727289B2 (ja) * 1993-09-29 1998-03-11 呉羽化学工業株式会社 ３−デオキシグルコソン誘導体及びその定量法
US5559038A (en) * 1994-05-04 1996-09-24 The Regents Of The University Of Colorado Gas chromatography/mass spectrometry determination of oxidized sulfhydryl amino acids
US6177266B1 (en) * 1996-04-29 2001-01-23 The United States Of America As Represented By The Secretary Of The Army Rapid identification of bacteria by mass spectrometry
US5731208A (en) * 1996-09-09 1998-03-24 Washington University Method of detecting conditions indicative of atherosclerosis
US6258605B1 (en) * 1999-03-26 2001-07-10 Neo Gen Screening, Inc. Clinical method for the genetic screening of newborns using tandem mass spectrometry

Also Published As

Publication number Publication date
ATE343130T1 (de) 2006-11-15
EP1113269A2 (de) 2001-07-04
EP1113269B1 (de) 2006-10-18
DE60031357T2 (de) 2007-08-30
EP1113269A3 (de) 2003-06-18
US20030199102A1 (en) 2003-10-23

Similar Documents

Publication Publication Date Title
DE60031357D1 (de) Testtablett, Kit und Verfahren zum Screening von Körperflüssigkeiten von Neugeborenen durch Tandem-Massenspektrometrie
DE60226797D1 (de) Instrument zum Einbringen von Befestigungselementen für Transplantate
DE60226941D1 (de) Verfahren zum Prüfen der Haut an mehreren Stellen
DE69635550D1 (de) Verfahren und mittel zur anregung des neuritwachstums
DE602004023360D1 (de) Verfahren zur Simulation von viskoelastischem Material
ATE433108T1 (de) Radiomarkierungssatz und bindungstest
DE602005027168D1 (de) Batterie, Verfahren zur deren Herstellung und Verfahren zum Prüfen von Elektrolytverlust
ATE325064T1 (de) Vorrichtung und verfahren zum prüfen von artikeln wie glaswaren
ATE271583T1 (de) Verfahren zum herstellen von reifen, damit erhaltene reifen und darin benutzte elastomerzusammensetzungen
HK1079571A1 (en) Methods for direct detection of individual methotrexate metabolites
DE60335357D1 (de) Vorrichtung zum einbeuteln von trockenen zutaten
ATA11042002A (de) Verfahren zur simulation des fahrverhaltens von fahrzeugen
ATE473728T1 (de) Verwendung von fluoreszierenden perlylenverbindungen zur behandlung menschlicher haare
DE10296203D2 (de) Verfahren zum Herstellen von lichtleitenden LED-Körpern in zwei räumlich und zeitlich getrennten Stufen
DE602005015054D1 (de) Vorrichtung zum Trennen von Treibladungsmodulen
DE50207435D1 (de) Verfahren zum beschreiben magnetoresistiver speicherzellen und mit diesem verfahren beschreibbarer magnetoresistiver speicher
DE602006013148D1 (de) Verfahren zum austrocknen und/oder entlauben von glyphosateresistenten kulturen
NO20040553L (no) BV8 Nukleinsyrer og polypeptider med mitogen aktivitet.
DE60305821D1 (de) Verfahren zum Wiegen von Poststücken
DE50310109D1 (de) Verfahren zum einfärben von düngemitteln
DE112004000431T8 (de) Verfahren zum Herstellen von Ventileinstellungsanordnungen
DE60315099D1 (de) Vorrichtung zum Wiegen und Sortieren von Früchten und dergleichen
ATE408832T1 (de) Verfahren zum nachweis von blutzell-antigenen und gegen diese gerichtete antikörper
DE60300585D1 (de) Verfahren zum Herstellen von polyolefinischer thermoplastischer Elastomerzusammensetzung
DE602004026439D1 (de) Lp-pla2-aktivitätstest mit hohem durchsatz

Legal Events

Date Code Title Description
8364 No opposition during term of opposition