DE60026584D1 - Microbielles wirkstoffabgabesystem - Google Patents
Microbielles wirkstoffabgabesystemInfo
- Publication number
- DE60026584D1 DE60026584D1 DE60026584T DE60026584T DE60026584D1 DE 60026584 D1 DE60026584 D1 DE 60026584D1 DE 60026584 T DE60026584 T DE 60026584T DE 60026584 T DE60026584 T DE 60026584T DE 60026584 D1 DE60026584 D1 DE 60026584D1
- Authority
- DE
- Germany
- Prior art keywords
- proteins
- allergic
- allergens
- subjects
- microorganisms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000000813 microbial effect Effects 0.000 title 1
- 239000000758 substrate Substances 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 abstract 5
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 206010020751 Hypersensitivity Diseases 0.000 abstract 4
- 239000013566 allergen Substances 0.000 abstract 4
- 244000005700 microbiome Species 0.000 abstract 3
- 208000026935 allergic disease Diseases 0.000 abstract 2
- 230000000172 allergic effect Effects 0.000 abstract 2
- 230000007815 allergy Effects 0.000 abstract 2
- 230000002052 anaphylactic effect Effects 0.000 abstract 2
- 208000010668 atopic eczema Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 206010002198 Anaphylactic reaction Diseases 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000192125 Firmicutes Species 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 230000036783 anaphylactic response Effects 0.000 abstract 1
- 208000003455 anaphylaxis Diseases 0.000 abstract 1
- 210000000612 antigen-presenting cell Anatomy 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 239000004816 latex Substances 0.000 abstract 1
- 229920000126 latex Polymers 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000001048 venom Anatomy 0.000 abstract 1
- 239000002435 venom Substances 0.000 abstract 1
- 231100000611 venom Toxicity 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5156—Animal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19503500P | 2000-04-06 | 2000-04-06 | |
US195035P | 2000-04-06 | ||
US09/731,375 US8153414B2 (en) | 2000-04-06 | 2000-12-06 | Microbial delivery system |
PCT/US2000/033121 WO2001066136A2 (en) | 2000-04-06 | 2000-12-06 | Microbial delivery system |
US731375 | 2000-12-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60026584D1 true DE60026584D1 (de) | 2006-05-04 |
DE60026584T2 DE60026584T2 (de) | 2007-03-08 |
Family
ID=26890647
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60026584T Expired - Lifetime DE60026584T2 (de) | 2000-04-06 | 2000-12-06 | Microbielles wirkstoffabgabesystem |
Country Status (11)
Country | Link |
---|---|
US (6) | US8153414B2 (de) |
EP (1) | EP1272213B1 (de) |
JP (3) | JP2004527450A (de) |
AT (1) | ATE319475T1 (de) |
AU (2) | AU2001219510B2 (de) |
CA (1) | CA2403292C (de) |
CY (1) | CY1105216T1 (de) |
DE (1) | DE60026584T2 (de) |
DK (1) | DK1272213T3 (de) |
ES (1) | ES2260078T3 (de) |
WO (1) | WO2001066136A2 (de) |
Families Citing this family (52)
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---|---|---|---|---|
US6698162B2 (en) * | 2000-03-23 | 2004-03-02 | Teikoku Pharma Usa, Inc. | Methods of producing a terminally sterilized topical patch preparation |
US8246945B2 (en) * | 2000-04-06 | 2012-08-21 | University Of Arkansas | Methods and reagents for decreasing clinical reaction to allergy |
DK1272213T3 (da) * | 2000-04-06 | 2006-07-10 | Seer Pharmaceuticals Llc | Mikrobielt afgivelsessystem |
CA2405424A1 (en) * | 2000-04-07 | 2001-10-18 | The Regents Of The University Of California | Synergistic improvements to polynucleotide vaccines |
US7083787B2 (en) * | 2000-11-15 | 2006-08-01 | Globeimmune, Inc. | Yeast-dendritic cell vaccines and uses thereof |
US7060687B2 (en) * | 2001-02-07 | 2006-06-13 | Genmont Biotechnology Co. | Live vaccines for allergy treatment |
CN104147597A (zh) * | 2002-12-16 | 2014-11-19 | 全球免疫股份有限公司 | 用于免疫治疗的基于酵母的疫苗 |
US7439042B2 (en) * | 2002-12-16 | 2008-10-21 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
US8343502B2 (en) * | 2002-12-16 | 2013-01-01 | Globeimmune, Inc. | Yeast-based vaccines as immunotherapy |
US20070231796A1 (en) * | 2003-09-17 | 2007-10-04 | The Regents Of The University Of California | Sensor and method for detection of a target substance |
JP5234445B2 (ja) * | 2004-10-05 | 2013-07-10 | 源一郎 杣 | 薬剤 |
WO2006044923A2 (en) * | 2004-10-18 | 2006-04-27 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis c infection |
EP1906997A2 (de) * | 2005-07-11 | 2008-04-09 | Globeimmune, Inc. | Zusammensetzungen und verfahren zur auslösung einer immunantwort auf escape-mutanten von gezielten therapien |
US20070172503A1 (en) | 2005-12-13 | 2007-07-26 | Mycologics,Inc. | Compositions and Methods to Elicit Immune Responses Against Pathogenic Organisms Using Yeast Based Vaccines |
TW200806789A (en) * | 2006-03-27 | 2008-02-01 | Globeimmune Inc | RAS mutation and compositions and methods related thereto |
US20080124355A1 (en) | 2006-09-22 | 2008-05-29 | David Gordon Bermudes | Live bacterial vaccines for viral infection prophylaxis or treatment |
BRPI0807828B8 (pt) * | 2007-02-02 | 2021-05-25 | Globeimmune Inc | composição compreendendo leveduras e usos das mesmas, bem como método para o crescimento de leveduras e kit para o cultivo de leveduras |
EP2134358A1 (de) * | 2007-03-19 | 2009-12-23 | Globeimmune, Inc. | Zusammensetzungen und verfahren zur gezielten ablation von escape-mutationen bei gezielten krebstherapien |
LT2244734T (lt) | 2008-02-01 | 2016-09-12 | Murdoch Childrens Research Institute | Alergeno toleravimo paskatinimo būdas |
EP2331125A4 (de) | 2008-09-19 | 2013-03-27 | Globeimmune Inc | Immuntherapie zur für chronische hepatitis-c-virus-infektionen |
US8241623B1 (en) | 2009-02-09 | 2012-08-14 | David Bermudes | Protease sensitivity expression system |
CA2759013C (en) | 2009-04-17 | 2021-10-19 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Combination immunotherapy compositions against cancer and methods |
CN102639702A (zh) * | 2009-07-13 | 2012-08-15 | 疫苗基因集团 | 使用可食用的微生物制造及施用的口服疫苗 |
CA2774326C (en) | 2009-09-14 | 2023-11-07 | Donald Bellgrau | Modulation of yeast-based immunotherapy products and responses |
US9597379B1 (en) | 2010-02-09 | 2017-03-21 | David Gordon Bermudes | Protease inhibitor combination with therapeutic proteins including antibodies |
US8524220B1 (en) | 2010-02-09 | 2013-09-03 | David Gordon Bermudes | Protease inhibitor: protease sensitivity expression system composition and methods improving the therapeutic activity and specificity of proteins delivered by bacteria |
US8771669B1 (en) | 2010-02-09 | 2014-07-08 | David Gordon Bermudes | Immunization and/or treatment of parasites and infectious agents by live bacteria |
EP2651439B1 (de) | 2010-12-17 | 2018-09-19 | Globeimmune, Inc. | Zusammensetzungen und verfahren zur behandlung oder vorbeugung von menschlicher adenovirus-36-infektion |
CA2827150C (en) | 2011-02-12 | 2018-09-11 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis b infection |
RU2619850C2 (ru) | 2011-03-17 | 2017-05-18 | Глоубиммьюн, Инк. | Иммунотерапевтические композиции на основе дрожжей с brachyury |
SG195383A1 (en) | 2011-06-14 | 2013-12-30 | Globeimmune Inc | Yeast-based compositions and methods for the treatment or prevention of hepatitis delta virus infection |
CA2844500C (en) | 2011-08-17 | 2022-05-10 | Globeimmune, Inc. | Yeast-muc1 immunotherapeutic compositions and uses thereof |
US20130216589A1 (en) * | 2012-02-17 | 2013-08-22 | Rich Content Biotech INC. | Oral vaccine for aquatic animals |
EP2841098A4 (de) | 2012-04-23 | 2016-03-02 | Allertein Therapeutics Llc | Nanopartikel zur behandlung von allergien |
EP2864792A1 (de) | 2012-06-26 | 2015-04-29 | Biodesix, Inc. | Massenspektrumsverfahren zur auswahl und zum ausschluss von krebspatienten für eine behandlung mit immunantworterzeugenden therapien |
WO2014049604A2 (en) * | 2012-09-05 | 2014-04-03 | Amrita Therapeutics Limited | A novel biomedical device for cancer therapy |
US9593339B1 (en) | 2013-02-14 | 2017-03-14 | David Gordon Bermudes | Bacteria carrying bacteriophage and protease inhibitors for the treatment of disorders and methods of treatment |
WO2014159609A1 (en) | 2013-03-14 | 2014-10-02 | Allergen Research Corporation | Peanut formulations and uses thereof |
HUE051831T2 (hu) | 2013-03-14 | 2021-03-29 | Aimmune Therapeutics Inc | Szájon át történõ deszenzitizálásra szolgáló földimogyoró-készítmények elõállítása |
US10507235B2 (en) | 2013-03-19 | 2019-12-17 | Globeimmune, Inc. | Yeast-based immunotherapy for Chordoma |
WO2014160747A2 (en) | 2013-03-26 | 2014-10-02 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of human immunodeficiency virus infection |
CA2907915C (en) | 2013-04-03 | 2023-03-07 | Allertein Therapeutics, Llc | Immunomodulatory nanoparticle compositions comprising a plurality of nanoparticles comprising biodegradable or biocompatible polymers and hydrophilic and hydrophobic cellular components |
US10226522B2 (en) | 2013-08-30 | 2019-03-12 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of tuberculosis |
US11215615B2 (en) | 2014-04-03 | 2022-01-04 | AllerGenis LLC | Peptides, reagents and methods for detecting food allergy |
EP3129036B1 (de) | 2014-04-11 | 2021-08-11 | Globeimmune, Inc. | Hefebasierte immuntherapie und typ-i-interferon-empfindlichkeit |
WO2017023840A1 (en) | 2015-08-03 | 2017-02-09 | Globeimmune, Inc. | Modified yeast-brachyury immunotherapeutic compositions |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
US11547662B2 (en) | 2017-10-25 | 2023-01-10 | Allero Therapeutics B.V. | Treatment of immune diseases by administration of antigen-specific formulations |
AU2018358125A1 (en) | 2017-11-02 | 2020-05-14 | Societe Des Produits Nestle S.A. | Methods of oral immunotherapy |
CN113966229A (zh) | 2019-05-10 | 2022-01-21 | 爱沐疗法公司 | 用于改善花生过敏患者的生活质量的方法 |
WO2021158857A1 (en) * | 2020-02-06 | 2021-08-12 | AllerGenis LLC | Assays for detecting peanut allergies |
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2000
- 2000-12-06 DK DK00982485T patent/DK1272213T3/da active
- 2000-12-06 AT AT00982485T patent/ATE319475T1/de active
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- 2003-12-04 US US10/728,051 patent/US20040234548A1/en not_active Abandoned
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AU1951001A (en) | 2001-09-17 |
US20130142817A1 (en) | 2013-06-06 |
CA2403292A1 (en) | 2001-09-13 |
US20030035810A1 (en) | 2003-02-20 |
JP2012207032A (ja) | 2012-10-25 |
US20110027298A1 (en) | 2011-02-03 |
WO2001066136A2 (en) | 2001-09-13 |
ES2260078T3 (es) | 2006-11-01 |
CY1105216T1 (el) | 2010-03-03 |
JP2009242427A (ja) | 2009-10-22 |
US20040234548A1 (en) | 2004-11-25 |
US20040208894A1 (en) | 2004-10-21 |
EP1272213A2 (de) | 2003-01-08 |
JP2004527450A (ja) | 2004-09-09 |
US8153414B2 (en) | 2012-04-10 |
CA2403292C (en) | 2011-02-08 |
DE60026584T2 (de) | 2007-03-08 |
EP1272213B1 (de) | 2006-03-08 |
AU2001219510B2 (en) | 2007-06-14 |
US20130243814A1 (en) | 2013-09-19 |
ATE319475T1 (de) | 2006-03-15 |
DK1272213T3 (da) | 2006-07-10 |
WO2001066136A3 (en) | 2001-12-27 |
US8815251B2 (en) | 2014-08-26 |
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