DE4393381T1 - Peptide - Google Patents
PeptideInfo
- Publication number
- DE4393381T1 DE4393381T1 DE4393381T DE4393381T DE4393381T1 DE 4393381 T1 DE4393381 T1 DE 4393381T1 DE 4393381 T DE4393381 T DE 4393381T DE 4393381 T DE4393381 T DE 4393381T DE 4393381 T1 DE4393381 T1 DE 4393381T1
- Authority
- DE
- Germany
- Prior art keywords
- peptides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10211—Podoviridae
- C12N2795/10222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Virology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929215009A GB9215009D0 (en) | 1992-07-15 | 1992-07-15 | Organic compounds |
GB929226415A GB9226415D0 (en) | 1992-12-18 | 1992-12-18 | Organic compounds |
GB929226859A GB9226859D0 (en) | 1992-12-23 | 1992-12-23 | Organic compounds |
GB929226861A GB9226861D0 (en) | 1992-12-23 | 1992-12-23 | Organic compounds |
GB939301691A GB9301691D0 (en) | 1993-01-28 | 1993-01-28 | Organic compounds |
GB939301692A GB9301692D0 (en) | 1993-01-28 | 1993-01-28 | Organic compounds |
GB939307673A GB9307673D0 (en) | 1993-04-14 | 1993-04-14 | Organic compounds |
GB939308033A GB9308033D0 (en) | 1993-04-19 | 1993-04-19 | Organic compounds |
PCT/EP1993/001749 WO1994002510A2 (en) | 1992-07-15 | 1993-07-06 | Analogs of pth |
Publications (1)
Publication Number | Publication Date |
---|---|
DE4393381T1 true DE4393381T1 (de) | 1995-04-27 |
Family
ID=27571302
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE4393381A Expired - Lifetime DE4393381B4 (de) | 1992-07-15 | 1993-07-06 | PTH-Verbindungen mit PTH-ähnlicher Aktivität, Verfahren zu deren Herstellung, diese enthaltende pharmazeutische Zusammensetzungen und deren Verwendungen |
DE4393381T Withdrawn DE4393381T1 (de) | 1992-07-15 | 1993-07-06 | Peptide |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE4393381A Expired - Lifetime DE4393381B4 (de) | 1992-07-15 | 1993-07-06 | PTH-Verbindungen mit PTH-ähnlicher Aktivität, Verfahren zu deren Herstellung, diese enthaltende pharmazeutische Zusammensetzungen und deren Verwendungen |
Country Status (25)
Country | Link |
---|---|
US (2) | US20050009147A1 (de) |
EP (1) | EP0672057B1 (de) |
JP (1) | JP3164463B2 (de) |
KR (1) | KR100321651B1 (de) |
CN (1) | CN1051769C (de) |
AT (1) | AT408100B (de) |
AU (1) | AU672790B2 (de) |
CA (1) | CA2100423C (de) |
CH (1) | CH688195A5 (de) |
CZ (1) | CZ286889B6 (de) |
DE (2) | DE4393381B4 (de) |
DK (1) | DK0672057T3 (de) |
ES (1) | ES2150948T3 (de) |
FI (1) | FI113872B (de) |
GB (1) | GB2269176B (de) |
GR (1) | GR3035089T3 (de) |
HK (1) | HK1004896A1 (de) |
HU (2) | HUT70459A (de) |
IL (1) | IL106326A (de) |
NO (1) | NO319448B1 (de) |
NZ (1) | NZ248137A (de) |
PT (1) | PT672057E (de) |
SG (1) | SG63625A1 (de) |
SK (1) | SK283485B6 (de) |
WO (1) | WO1994002510A2 (de) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5814603A (en) * | 1992-06-12 | 1998-09-29 | Affymax Technologies N.V. | Compounds with PTH activity |
WO1995011697A1 (fr) * | 1993-10-27 | 1995-05-04 | Chugai Seiyaku Kabushiki Kaisha | Accelerateur de guerison utilise en chondroplastie |
US5955425A (en) * | 1996-08-02 | 1999-09-21 | National Research Council Of Canada | Parathyroid hormone analogues for the treatment of osteoporosis |
US6110892A (en) | 1994-06-20 | 2000-08-29 | National Research Council Of Canada | Parathyroid hormone analogues for the treatment of osteoporosis |
US5556940A (en) * | 1994-06-20 | 1996-09-17 | National Research Council Of Canada | Parathyroid hormone analogues for the treatment of osteoporosis |
CO4410206A1 (es) * | 1994-07-28 | 1997-01-09 | Sandoz Ag | DERIVADOS DE PTH o PTHrP, SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN |
US5747456A (en) * | 1994-12-19 | 1998-05-05 | Beth Israel Deaconess Medical Center | Continuous low-dose administration of parathyroid hormone or its agonist |
CA2178894A1 (en) * | 1995-06-15 | 1996-12-16 | Tsunehiko Fukuda | Parathyroid hormone derivatives and their use |
US7410948B2 (en) | 1995-07-13 | 2008-08-12 | Societe De Conseils De Recherches Et D'applications Scientifiques, Sas | Analogs of parathyroid hormone |
US5955574A (en) * | 1995-07-13 | 1999-09-21 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A. | Analogs of parathyroid hormone |
US5969095A (en) * | 1995-07-13 | 1999-10-19 | Biomeasure, Inc. | Analogs of parathyroid hormone |
US6544949B1 (en) | 1995-07-13 | 2003-04-08 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Analogs of parathyroid hormone |
US5723577A (en) * | 1995-07-13 | 1998-03-03 | Biomeasure Inc. | Analogs of parathyroid hormone |
EP1352912A1 (de) * | 1996-08-02 | 2003-10-15 | National Research Council Of Canada | Analoge des Parathormons zur Behandlung der Osteoporose |
EE9900039A (et) * | 1996-08-02 | 1999-08-16 | National Research Council Of Canada | Paratüreoidhormooni analoogid osteoporoosi raviks |
BR9808786A (pt) | 1997-05-14 | 2000-07-11 | Rhone Poulenc Rorer Pharma | Composto peptìdio cìclico ou um seu sal ou pró-medicamento farmaceuticamente aceitáveis, composição farmacêutica, e, processos para tratar doenças associadas com a regulagem do cálcio em um paciente e para tratar a osteopenia ou a osteoporose em um mamìfero hospedeiro |
EP1721617A3 (de) * | 1997-07-22 | 2008-05-28 | Chugai Seiyaku Kabushiki Kaisha | Zahnärztliche Therapeutika enthaltend Parathyroidhormon |
ES2244090T3 (es) * | 1997-09-09 | 2005-12-01 | F. Hoffmann-La Roche Ag | Curacion de fracturas utilizando analogos de pthrp. |
EP1075491B1 (de) | 1998-05-05 | 2008-04-16 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Pth2 rezeptor selektive verbindungen |
WO2000023594A1 (en) | 1998-10-22 | 2000-04-27 | The General Hospital Corporation | BIOACTIVE PEPTIDES AND PEPTIDE DERIVATIVES OF PARATHYROID HORMONE (PTH) AND PARATHYROID HORMONE-RELATED PEPTIDE (PTHrP) |
JP4486258B2 (ja) | 1998-11-25 | 2010-06-23 | ザ・ジェネラル・ホスピタル・コーポレイション | ヒト副甲状腺ホルモンの改変、調製および使用 |
EP1147133B1 (de) * | 1998-12-31 | 2008-08-06 | The General Hospital Corporation | Peptide, bestehend aus zwei funktionellen PTH-Domänen, die durch ein Linkermolekül verknüpft sind, und Derivate davon |
US7057012B1 (en) | 1998-12-31 | 2006-06-06 | The General Hospital Corporation | PTH functional domain conjugate peptides, derivatives thereof and novel tethered ligand-receptor molecules |
EP1141237B1 (de) | 1998-12-31 | 2005-11-02 | The General Hospital Corporation | Pth rezeptor und testverfahren unter verwendung desselben |
US20050272652A1 (en) * | 1999-03-29 | 2005-12-08 | Gault Victor A | Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity |
DE19916419B4 (de) * | 1999-04-08 | 2005-06-16 | Schering Ag | Kombinationspräparat aus Vitamin-D-Metaboliten oder Vitamin-D-Analoga und einem Östrogenpartialagonisten zur Behandlung von Osteoporose |
AU7734800A (en) | 1999-09-29 | 2001-04-30 | General Hospital Corporation, The | Polypeptide derivatives of parathyroid hormone (pth) |
EP1439854B1 (de) | 2001-07-23 | 2016-12-14 | The General Hospital Corporation | Parathormon (pth)-analoga mit beschränkter konformation |
JP2005525312A (ja) | 2002-01-10 | 2005-08-25 | オステオトロフィン エルエルシー | 骨同化物質を用いた骨疾患の治療方法 |
GB0205693D0 (en) * | 2002-03-09 | 2002-04-24 | Astrazeneca Ab | Chemical compounds |
US7906480B2 (en) | 2002-05-23 | 2011-03-15 | Michael Holick | Use of a parathyroid hormone peptide analogs for the treatment of vaginal atrophy |
AU2002951372A0 (en) * | 2002-09-13 | 2002-09-26 | St Vincent's Institute Of Medical Research | Parathyroid hormone-like polypeptides |
US7795220B2 (en) | 2003-03-19 | 2010-09-14 | The General Hospital Corporation | Conformationally constrained parathyroid hormones with alpha-helix stabilizers |
WO2005009358A2 (en) | 2003-07-17 | 2005-02-03 | The General Hospital Corporation | Conformationally constrained parathyroid hormone (pth) analogs |
US9046537B2 (en) | 2003-09-22 | 2015-06-02 | Enzo Biochem, Inc. | Method for treating inflammation by administering a compound which binds LDL-receptor-related protein (LRP) ligand binding domain |
EP1744683B1 (de) | 2004-05-13 | 2016-03-16 | Alza Corporation | Gerät und verfahren für die transdermale abgabe von parathyroidhormon-mitteln |
US9052324B2 (en) | 2004-05-19 | 2015-06-09 | Enzo Biochem, Inc. | Compounds and assays for controlling Wnt activity |
KR20070115947A (ko) | 2005-02-11 | 2007-12-06 | 아밀린 파마슈티칼스, 인크. | 선택가능한 특성들을 가지는 gip 유사체 및 하이브리드폴리펩타이드 |
US8263545B2 (en) * | 2005-02-11 | 2012-09-11 | Amylin Pharmaceuticals, Inc. | GIP analog and hybrid polypeptides with selectable properties |
WO2007028632A2 (en) * | 2005-09-08 | 2007-03-15 | Uutech Limited | Analogs of gastric inhibitory polypeptide as a treatment for age related decreased pancreatic beta cell function |
WO2007028633A2 (en) * | 2005-09-08 | 2007-03-15 | Uutech Limited | Treatment of diabetes related obesity |
AU2006315132A1 (en) * | 2005-11-10 | 2007-05-24 | Board Of Control Of Michigan Technological University | Black bear parathyroid hormone and methods of using black bear parathyroid hormone |
EP2054077A4 (de) * | 2006-08-04 | 2010-10-13 | Gen Hospital Corp | Polypeptidderivate des parathyroidhormons (pth) |
US8497240B2 (en) | 2006-08-17 | 2013-07-30 | Amylin Pharmaceuticals, Llc | DPP-IV resistant GIP hybrid polypeptides with selectable properties |
EP2084183B1 (de) | 2006-10-13 | 2010-05-26 | Eli Lilly & Company | Pegyliertes pth als pth-rezeptormodulatoren und ihre verwendung |
CA3017668C (en) | 2007-08-01 | 2021-11-09 | The General Hospital Corporation | Screening methods using g-protein coupled receptors and related compositions |
CA2740873C (en) | 2008-10-17 | 2019-09-10 | Wisconsin Alumni Research Foundation | Method of making biologically active alpha-beta peptides |
CN102448482A (zh) | 2009-03-27 | 2012-05-09 | 范安德尔研究所 | 甲状旁腺素肽和甲状旁腺素相关蛋白肽及使用方法 |
EP2509996A1 (de) | 2009-12-07 | 2012-10-17 | Michigan Technological University | Schwarzbär-parathyroid-hormon und verfahren zur verwendung des schwarzbär-parathyroid-hormons |
MX358161B (es) | 2010-05-13 | 2018-08-06 | The General Hospital Corp Star | Analogos de hormona paratiroidea y usos para los mismos. |
US8609621B2 (en) | 2010-11-15 | 2013-12-17 | E I Du Pont De Nemours And Company | Acid-cleavable linkers exhibiting altered rates of acid hydrolysis |
JP2014508765A (ja) * | 2011-03-01 | 2014-04-10 | スローン − ケタリング・インスティテュート・フォー・キャンサー・リサーチ | 副甲状腺ホルモン類似体、組成物およびその使用 |
US20170037086A1 (en) * | 2014-04-09 | 2017-02-09 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles with pth activity |
JP2022511515A (ja) | 2018-12-20 | 2022-01-31 | ケーエスキュー セラピューティクス, インコーポレイテッド | 置換されたピラゾロピリミジン及び置換されたプリンならびにユビキチン特異的プロセシングプロテアーゼ1(usp1)阻害剤としてのそれらの使用 |
CN116615424A (zh) | 2020-10-30 | 2023-08-18 | Ksq治疗公司 | 经取代的吡唑并嘧啶的固态形式和其用途 |
WO2023066881A1 (en) | 2021-10-18 | 2023-04-27 | Astrazeneca Ab | Inhibition of map3k15 for treating and preventing diabetes |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3886132A (en) * | 1972-12-21 | 1975-05-27 | Us Health | Human parathyroid hormone |
US4423037A (en) * | 1982-05-13 | 1983-12-27 | The General Hospital Corporation | Inhibitors of peptide hormone action |
FR2550204B1 (fr) * | 1983-08-05 | 1987-11-13 | Toyo Jozo Kk | Derives peptidiques de (nle8,nle1b, tyr34)-h-pth |
US4752585A (en) * | 1985-12-17 | 1988-06-21 | Cetus Corporation | Oxidation-resistant muteins |
US5420242A (en) * | 1986-10-22 | 1995-05-30 | Kaare M. Gautvik | Production of human parathyroid hormone from microorganisms |
US4771124A (en) * | 1987-05-26 | 1988-09-13 | Merck & Co., Inc. | Parathyroid hormone antagonists with simplified synthetic methodology |
EP0293158A3 (de) * | 1987-05-26 | 1990-05-09 | Merck & Co. Inc. | Parathyroide Hormon-Antagonisten |
US5001223A (en) * | 1987-05-26 | 1991-03-19 | Merck & Co., Inc. | Parathyroid hormone antagonists with enhanced metabolic properties |
DE3725320A1 (de) * | 1987-07-30 | 1989-02-09 | Biotechnolog Forschung Gmbh | Expressionsvektoren und verfahren unter deren verwendung zur gewinnung von cro/ss-galaktosidase/pth-fusionsproteinen und von pth |
US4968669A (en) * | 1988-05-09 | 1990-11-06 | Merck & Co., Inc. | Parathyroid hormone antagonists |
JPH03504201A (ja) * | 1989-02-23 | 1991-09-19 | ゲゼルシャフト・フュア・ビオテクノロギッシェ・フォルシュンク・ミット・ベシュレンクテル・ハフツング (ゲー・ベー・エフ) | Pth変種をコードするdna配列、pth変種、発現ベクター、細菌宿主、利用と治療用組成物 |
CA2040264A1 (en) * | 1990-04-12 | 1991-10-13 | Tatsuhiko Kanmera | Parathyroid hormone antagonists |
US5093233A (en) * | 1990-04-25 | 1992-03-03 | Merck & Co., Inc. | Antagonists with position 13 modification |
GB9020544D0 (en) * | 1990-09-20 | 1990-10-31 | Sandoz Ltd | Improvements in or relating to organic compounds |
JPH0532696A (ja) * | 1990-09-28 | 1993-02-09 | Takeda Chem Ind Ltd | 副甲状腺ホルモン誘導体 |
AU9103791A (en) * | 1990-12-21 | 1992-07-22 | Allelix Biopharmaceuticals Inc. | Oxidation resistant variants of parathyroid hormone |
ES2087323T3 (es) * | 1991-02-19 | 1996-07-16 | Takeda Chemical Industries Ltd | Metodo para producir peptidos exentos de cisteina. |
US5317010A (en) * | 1991-10-10 | 1994-05-31 | Peter K. T. Pang | Parathyroid hormone analogues substituted at AA 25, 26, 27, and use in osteoporosis treatment |
US5434246A (en) * | 1992-03-19 | 1995-07-18 | Takeda Chemical Industries, Ltd. | Parathyroid hormone derivatives |
US5382658A (en) * | 1992-04-03 | 1995-01-17 | Allelix Biopharmaceuticals Inc. | Stability-enhanced variants of parathyroid hormone |
US5589452A (en) * | 1992-07-14 | 1996-12-31 | Syntex (U.S.A.) Inc. | Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis |
-
1993
- 1993-06-29 AU AU41566/93A patent/AU672790B2/en not_active Ceased
- 1993-07-06 HU HU9500115A patent/HUT70459A/hu unknown
- 1993-07-06 SK SK43-95A patent/SK283485B6/sk unknown
- 1993-07-06 CH CH00784/94A patent/CH688195A5/de not_active IP Right Cessation
- 1993-07-06 DE DE4393381A patent/DE4393381B4/de not_active Expired - Lifetime
- 1993-07-06 DE DE4393381T patent/DE4393381T1/de not_active Withdrawn
- 1993-07-06 EP EP93915814A patent/EP0672057B1/de not_active Expired - Lifetime
- 1993-07-06 ES ES93915814T patent/ES2150948T3/es not_active Expired - Lifetime
- 1993-07-06 AT AT0903993A patent/AT408100B/de not_active IP Right Cessation
- 1993-07-06 CZ CZ199588A patent/CZ286889B6/cs not_active IP Right Cessation
- 1993-07-06 PT PT93915814T patent/PT672057E/pt unknown
- 1993-07-06 DK DK93915814T patent/DK0672057T3/da active
- 1993-07-06 WO PCT/EP1993/001749 patent/WO1994002510A2/en active IP Right Grant
- 1993-07-12 GB GB9314384A patent/GB2269176B/en not_active Expired - Fee Related
- 1993-07-12 SG SG1996008052A patent/SG63625A1/en unknown
- 1993-07-13 CA CA002100423A patent/CA2100423C/en not_active Expired - Fee Related
- 1993-07-13 IL IL106326A patent/IL106326A/xx not_active IP Right Cessation
- 1993-07-13 NZ NZ248137A patent/NZ248137A/en not_active IP Right Cessation
- 1993-07-14 CN CN93116483A patent/CN1051769C/zh not_active Expired - Fee Related
- 1993-07-14 KR KR1019930013440A patent/KR100321651B1/ko not_active IP Right Cessation
- 1993-07-14 JP JP17416393A patent/JP3164463B2/ja not_active Expired - Fee Related
-
1995
- 1995-01-12 NO NO19950123A patent/NO319448B1/no unknown
- 1995-01-13 FI FI950171A patent/FI113872B/fi not_active IP Right Cessation
- 1995-06-21 HU HU95P/P00320P patent/HU211856A9/hu unknown
-
1998
- 1998-05-12 HK HK98104077A patent/HK1004896A1/xx not_active IP Right Cessation
-
2000
- 2000-12-15 GR GR20000402777T patent/GR3035089T3/el unknown
-
2004
- 2004-05-18 US US10/848,279 patent/US20050009147A1/en not_active Abandoned
-
2008
- 2008-07-08 US US12/169,134 patent/US20080318838A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE4393381T1 (de) | Peptide | |
DE69332485D1 (de) | Immunmodulierende peptide | |
DE69129395D1 (de) | Antimikrobielle Peptide | |
DE69315842D1 (de) | Peptidverbindungen | |
NO942066L (no) | Peptidderivater | |
DK6893D0 (da) | Peptid | |
IS4115A (is) | Ný peptíð | |
FI940109A (fi) | Peptidejä | |
FI970168A (fi) | Peptidejä | |
DE69427363T2 (de) | Plättchenaggregationsinhibierende peptide | |
NO943540D0 (no) | Antivirale peptider | |
BR9606756A (pt) | Peptídeo | |
DE69314120T2 (de) | Phospholipase c hemmendes peptid | |
NO981052D0 (no) | Peptidderivater | |
NO932237D0 (no) | Lineaere peptider | |
MA22717A1 (fr) | Peptides hemoregulateurs | |
NO981051D0 (no) | Peptidderivater | |
NO177858C (no) | Peptid | |
LV10286A (lv) | Peptidu savienojumi | |
DE69638206D1 (de) | Antineoplastische Peptide | |
DE69420044D1 (de) | Blutregulierende peptide | |
LV10287A (lv) | Peptidu savienojumi | |
DE68914057D1 (de) | Peptide. | |
ITMI922963A0 (it) | Peptidi ciclici | |
SE9504467D0 (sv) | Peptide |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8127 | New person/name/address of the applicant |
Owner name: NOVARTIS AG, BASEL, CH |
|
8110 | Request for examination paragraph 44 | ||
8125 | Change of the main classification |
Ipc: C07K 14/635 |
|
8364 | No opposition during term of opposition | ||
8328 | Change in the person/name/address of the agent |
Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336 |
|
8339 | Ceased/non-payment of the annual fee | ||
R119 | Application deemed withdrawn, or ip right lapsed, due to non-payment of renewal fee |
Effective date: 20110201 |
|
R082 | Change of representative |
Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN, DE Representative=s name: DR. SCHOEN & PARTNER, DE Representative=s name: DR. SCHOEN, NEYMEYR & PARTNER MBB, DE |