DE3682882D1 - Menschliches immunoglobulin-g-fc-region-protein und dessen herstellung. - Google Patents
Menschliches immunoglobulin-g-fc-region-protein und dessen herstellung.Info
- Publication number
- DE3682882D1 DE3682882D1 DE8686117996T DE3682882T DE3682882D1 DE 3682882 D1 DE3682882 D1 DE 3682882D1 DE 8686117996 T DE8686117996 T DE 8686117996T DE 3682882 T DE3682882 T DE 3682882T DE 3682882 D1 DE3682882 D1 DE 3682882D1
- Authority
- DE
- Germany
- Prior art keywords
- protein
- region
- production
- human immunoglobulin
- immunoglobulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60292298A JPS62153300A (ja) | 1985-12-26 | 1985-12-26 | ヒト免疫グロブリンGFc領域蛋白質およびその製造方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3682882D1 true DE3682882D1 (de) | 1992-01-23 |
Family
ID=17779944
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686117996T Expired - Lifetime DE3682882D1 (de) | 1985-12-26 | 1986-12-23 | Menschliches immunoglobulin-g-fc-region-protein und dessen herstellung. |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0227110B1 (de) |
JP (1) | JPS62153300A (de) |
DE (1) | DE3682882D1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2639231A1 (fr) * | 1988-11-23 | 1990-05-25 | Merieux Inst | Utilisation de fragments fc d'immunoglobulines g humaines, de peptides analogues du fragment fc, ou d'immunoglobulines g humaines dans l'obtention d'un medicament preparatoire a l'administration chez l'homme, dans un but therapeutique ou de diagnostic, d'anticorps monoclonaux |
DK0417563T3 (da) | 1989-09-12 | 2000-11-06 | Hoffmann La Roche | TNF-bindende proteiner |
DE69416078T2 (de) * | 1993-10-22 | 1999-05-27 | Nihon Mediphysics Co Ltd | Peptide mit Affinität für Entzündungen und deren radiomarkierte, diagnostische Zusammensetzungen |
AU2004282984B2 (en) | 2003-11-13 | 2011-07-14 | Hanmi Science Co., Ltd. | Protein complex using immunoglobulin fragment andmethod for the preparation thereof |
US20080089892A1 (en) * | 2004-01-12 | 2008-04-17 | Eli Lilly And Co. | Fc Region Variants |
UA97628C2 (ru) | 2005-08-16 | 2012-03-12 | Ханми Холдингз Ко., Лтд. | Способ получения fc-фрагмента иммуноглобулина, свободного от начального метионинового остатка, в массовом масштабе |
KR20080050591A (ko) | 2005-09-01 | 2008-06-09 | 아레스 트레이딩 에스.에이. | 시신경염 치료 |
JP2009537605A (ja) | 2006-05-24 | 2009-10-29 | メルク セローノ ソシエテ アノニム | 多発性硬化症を治療するためのクラドリビン・レジメン |
WO2013138643A1 (en) | 2012-03-16 | 2013-09-19 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Soluble engineered monomeric fc |
PT3087095T (pt) * | 2013-12-24 | 2019-10-09 | Argenx Bvba | Antagonistas de fcrn e métodos de utilização |
JP2022535908A (ja) | 2019-06-07 | 2022-08-10 | アルジェニクス ビーブイ | 皮下投与に好適なFcRnインヒビターの医薬製剤 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
FR2556219B1 (fr) * | 1983-12-07 | 1987-06-26 | Merieux Inst | Nouveau medicament immunomodulateur, a base de fragments fc d'igg humaines |
JPS61134325A (ja) * | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
-
1985
- 1985-12-26 JP JP60292298A patent/JPS62153300A/ja active Pending
-
1986
- 1986-12-23 DE DE8686117996T patent/DE3682882D1/de not_active Expired - Lifetime
- 1986-12-23 EP EP86117996A patent/EP0227110B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0227110B1 (de) | 1991-12-11 |
EP0227110A2 (de) | 1987-07-01 |
JPS62153300A (ja) | 1987-07-08 |
EP0227110A3 (en) | 1988-08-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |