DE3851309T2 - Transfizierte Zellstämme, die den menschlichen Rhinovirus-Hauptrezeptor exprimieren. - Google Patents

Transfizierte Zellstämme, die den menschlichen Rhinovirus-Hauptrezeptor exprimieren.

Info

Publication number
DE3851309T2
DE3851309T2 DE3851309T DE3851309T DE3851309T2 DE 3851309 T2 DE3851309 T2 DE 3851309T2 DE 3851309 T DE3851309 T DE 3851309T DE 3851309 T DE3851309 T DE 3851309T DE 3851309 T2 DE3851309 T2 DE 3851309T2
Authority
DE
Germany
Prior art keywords
receptor protein
human
cell lines
human rhinovirus
rhinovirus receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3851309T
Other languages
English (en)
Other versions
DE3851309D1 (de
Inventor
Alan Mcclelland
Ann Marie Meyer
Jeffrey M Greve
Gary Davis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Inc filed Critical Miles Inc
Publication of DE3851309D1 publication Critical patent/DE3851309D1/de
Application granted granted Critical
Publication of DE3851309T2 publication Critical patent/DE3851309T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32711—Rhinovirus
    • C12N2770/32722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Inert Electrodes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE3851309T 1987-12-08 1988-11-28 Transfizierte Zellstämme, die den menschlichen Rhinovirus-Hauptrezeptor exprimieren. Expired - Fee Related DE3851309T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13037887A 1987-12-08 1987-12-08
US26257088A 1988-10-25 1988-10-25

Publications (2)

Publication Number Publication Date
DE3851309D1 DE3851309D1 (de) 1994-10-06
DE3851309T2 true DE3851309T2 (de) 1994-12-22

Family

ID=26828436

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3851309T Expired - Fee Related DE3851309T2 (de) 1987-12-08 1988-11-28 Transfizierte Zellstämme, die den menschlichen Rhinovirus-Hauptrezeptor exprimieren.

Country Status (7)

Country Link
EP (1) EP0319815B1 (de)
JP (1) JPH0242977A (de)
AT (1) ATE110771T1 (de)
AU (1) AU623105B2 (de)
CA (1) CA1341055C (de)
DE (1) DE3851309T2 (de)
ES (1) ES2058219T3 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5284931A (en) 1987-05-04 1994-02-08 Dana Farber Cancer Institute Intercellular adhesion molecules, and their binding ligands
US7354588B1 (en) 1987-05-04 2008-04-08 Dana Farber Cancer Institute Functional derivatives of ICAM-1 with altered ability to bind LFA-1 or HRV
US5831036A (en) * 1987-05-04 1998-11-03 Dana Farber Cancer Institute Soluble fragments of human intercellular adhesion molecule-1
US5336603A (en) * 1987-10-02 1994-08-09 Genentech, Inc. CD4 adheson variants
US6710169B2 (en) 1987-10-02 2004-03-23 Genentech, Inc. Adheson variants
US6514936B1 (en) 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
US6051231A (en) * 1988-09-01 2000-04-18 Bayer Corporation Antiviral methods and prepations
ZA896668B (en) * 1988-09-01 1990-06-27 Molecular Therapeutics Inc A human rhinovirus receptor protein that inhibits virus infectivity
US6143298A (en) * 1988-09-01 2000-11-07 Bayer Corporation Soluble truncated forms of ICAM-1
ES2141076T3 (es) 1988-09-01 2000-03-16 Bayer Ag Proteina del receptor de rinovirus humano que inhibe la infectividad del virus.
ATE125708T1 (de) * 1988-09-28 1995-08-15 Dana Farber Cancer Inst Inc Interzellulare adhäsions-moleküle und deren bindungsliganden.
US5235049A (en) * 1989-01-24 1993-08-10 Molecular Therapeutics, Inc. Nucleic acid sequences encoding a soluble molecule (SICAM-1) related to but distinct from ICAM-1
NO900155L (no) * 1989-01-24 1990-07-25 Molecular Therapeutics Inc Et opploeselig molekyl som er relatert til, men forskjellig fra icam-1.
CA2008368C (en) * 1989-01-24 2003-04-08 Jeffrey Greve Soluble molecule related to but distinct from icam-1
DK0387701T3 (da) * 1989-03-09 1992-12-07 Boehringer Ingelheim Pharma Anvendelse af intercellulære adhæsionsmolekyler samt deres bindende ligander ved behandling af astma
DE69033983T2 (de) * 1989-03-16 2003-03-20 Blood Res Center Verwendung von funktionellen Derivaten des Interzellulär-Adhäsions-Moleküls ICAM-1 in einer Antivirus-Therapie
US6797270B1 (en) * 1989-03-16 2004-09-28 Center For Blood Research, Inc. Functional derivatives of the intercellular adhesion molecule ICAM-1 in anti-viral therapy
US6777191B1 (en) 1989-03-16 2004-08-17 Center For Blood Research, Inc. Use of functional derivatives of the intercellular adhesion molecule ICAM-1 in diagnosis of viral infection
DK0468257T3 (da) * 1990-07-20 2000-03-27 Bayer Ag Multimer form af human rhinovirusreceptorprotein
US5674982A (en) * 1990-07-20 1997-10-07 Bayer Corporation Multimeric form of human rhinovirus receptor protein
US5871733A (en) * 1990-07-20 1999-02-16 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
US6107461A (en) * 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US6130202A (en) * 1990-07-20 2000-10-10 Bayer Corporation Antiviral methods
EP0510483A1 (de) * 1991-04-22 1992-10-28 Boehringer Ingelheim Pharmaceuticals Inc. Verfahren zum Nachweis von Viren
US7241569B2 (en) 1993-01-18 2007-07-10 Olympus Corporation Method and a device for the evaluation of biopolymer fitness
DK0679251T3 (da) 1993-01-18 1999-01-25 Evotec Biosystems Aktiengesell Fremgangsmåde og apparat til vurdering af biopolymerers fitness
CN113402601A (zh) * 2021-06-09 2021-09-17 河南中泽生物工程有限公司 一种抗非洲猪瘟病毒p54蛋白单克隆抗体的制备方法及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS551594A (en) * 1978-06-12 1980-01-08 Corning Glass Works Measuring antigen receptor on cell membrane
EP0169146A3 (de) * 1984-07-20 1988-07-20 Merck & Co. Inc. Monoklonale Antikörper gegen den Rezeptor des menschlichen Rhinovirus
EP0169729A3 (de) * 1984-07-23 1988-08-03 Becton Dickinson and Company Gewinnung von Zellenrezeptoren
DE3712678A1 (de) * 1987-04-14 1988-10-27 Boehringer Ingelheim Int Rezeptor der kleinen rhinovirus rezeptor gruppe
US4893075A (en) * 1988-08-29 1990-01-09 Eaton Corporation Dual speed sensor pickup assembly with anti-cross talk coils

Also Published As

Publication number Publication date
AU623105B2 (en) 1992-05-07
ES2058219T3 (es) 1994-11-01
JPH0242977A (ja) 1990-02-13
DE3851309D1 (de) 1994-10-06
EP0319815A2 (de) 1989-06-14
EP0319815A3 (en) 1989-09-27
AU2659488A (en) 1989-06-08
ATE110771T1 (de) 1994-09-15
CA1341055C (en) 2000-07-18
EP0319815B1 (de) 1994-08-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee