DE3785936D1 - Makrolid-derivate, ihre herstellung und ihre verwendung. - Google Patents

Makrolid-derivate, ihre herstellung und ihre verwendung.

Info

Publication number
DE3785936D1
DE3785936D1 DE8989112109T DE3785936T DE3785936D1 DE 3785936 D1 DE3785936 D1 DE 3785936D1 DE 8989112109 T DE8989112109 T DE 8989112109T DE 3785936 T DE3785936 T DE 3785936T DE 3785936 D1 DE3785936 D1 DE 3785936D1
Authority
DE
Germany
Prior art keywords
production
macrolide derivatives
macrolide
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989112109T
Other languages
English (en)
Other versions
DE3785936T2 (de
Inventor
Kazuo C O Sankyo Agricult Sato
Toshiaki C O Sankyo Agri Yanai
Takao C O Sankyo Agricu Kinoto
Toshimitsu C O Sankyo C Toyama
Keiji C O Sankyo Agricu Tanaka
Akira C O Sankyo Agric Nishida
Bruno Frei
Anthony O'sullivan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of DE3785936D1 publication Critical patent/DE3785936D1/de
Application granted granted Critical
Publication of DE3785936T2 publication Critical patent/DE3785936T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/02Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
    • A01N47/06Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom containing —O—CO—O— groups; Thio analogues thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE8989112109T 1986-03-25 1987-03-23 Makrolid-derivate, ihre herstellung und ihre verwendung. Expired - Fee Related DE3785936T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6631586 1986-03-25
JP13756886 1986-06-13

Publications (2)

Publication Number Publication Date
DE3785936D1 true DE3785936D1 (de) 1993-06-24
DE3785936T2 DE3785936T2 (de) 1993-08-26

Family

ID=26407512

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8787302494T Expired - Fee Related DE3767560D1 (de) 1986-03-25 1987-03-23 Makrolide verbindungen, ihre herstellung und verwendung.
DE8989112109T Expired - Fee Related DE3785936T2 (de) 1986-03-25 1987-03-23 Makrolid-derivate, ihre herstellung und ihre verwendung.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE8787302494T Expired - Fee Related DE3767560D1 (de) 1986-03-25 1987-03-23 Makrolide verbindungen, ihre herstellung und verwendung.

Country Status (20)

Country Link
US (2) US4963582A (de)
EP (2) EP0246739B1 (de)
KR (1) KR940009790B1 (de)
CN (2) CN1022834C (de)
AR (1) AR243191A1 (de)
AT (1) ATE89560T1 (de)
AU (1) AU592858B2 (de)
BR (1) BR8701302A (de)
CA (1) CA1317935C (de)
DE (2) DE3767560D1 (de)
DK (1) DK170046B1 (de)
ES (2) ES2019932B3 (de)
FI (1) FI95707C (de)
GR (1) GR3001548T3 (de)
HU (1) HU198496B (de)
IE (1) IE61347B1 (de)
IL (1) IL81997A (de)
NZ (1) NZ219759A (de)
PT (1) PT84549B (de)
RU (2) RU2024527C1 (de)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
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EP0246739B1 (de) * 1986-03-25 1991-01-23 Sankyo Company Limited Makrolide Verbindungen, ihre Herstellung und Verwendung
EP0253378A3 (de) * 1986-07-18 1988-03-23 Ciba-Geigy Ag 13Beta-Alkyl-derivate von S541-Antibiotika zur Bekämpfung von Parasiten an Nutztieren und Pflanzen
GB8721371D0 (en) * 1987-09-11 1987-10-21 Glaxo Group Ltd Chemical compounds
AU613521B2 (en) * 1988-09-02 1991-08-01 Sankyo Company Limited 13-substituted milbemycin derivatives, their preparation and use
US5015630A (en) * 1989-01-19 1991-05-14 Merck & Co., Inc. 5-oxime avermectin derivatives
NZ233680A (en) * 1989-05-17 1995-02-24 Beecham Group Plc Avermectins and milbemycins and compositions thereof
JPH085894B2 (ja) * 1990-03-01 1996-01-24 三共株式会社 ミルベマイシンエーテル誘導体
DE4032147A1 (de) * 1990-10-10 1992-04-16 Bayer Ag Verwendung von substituierten 2-mercaptonicotinsaeurederivaten zur bekaempfung von endoparasiten, neue substituierte 2-mercaptonicotinsaeurederivate und verfahren zu ihrer herstellung
US5290804A (en) * 1991-05-01 1994-03-01 Merck & Co., Inc. Anthelmintic milbemycin analogs of novel microorganisms
RU2086552C1 (ru) * 1991-12-18 1997-08-10 Санкио Компани Лимитед Производные 13-(замещенного тио)ацетоксимилбемицина, способ их получения, инсектицидная композиция и способ защиты растений
US5345114A (en) * 1992-10-15 1994-09-06 Qiyuan Ma Superconductor logic and switching circuits
US5614470A (en) * 1994-04-01 1997-03-25 Sankyo Company, Limited 13-substituted milbemycin derivatives, their preparation and their use
ES2155172T3 (es) * 1995-09-29 2001-05-01 Sankyo Co Derivados milbemicina 5-oxima 13-sustituidos, su preparacion y su uso contra insectos y otras plagas.
WO1999027906A1 (en) * 1997-12-03 1999-06-10 Merck & Co., Inc. Long acting injectable formulations containing hydrogenated castor oil
AT501406A1 (de) * 1997-12-23 2006-08-15 Syngenta Participations Ag Verfahren zur bekämpfung von mollusken
US6733767B2 (en) 1998-03-19 2004-05-11 Merck & Co., Inc. Liquid polymeric compositions for controlled release of bioactive substances
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WO2001083500A1 (en) * 2000-04-27 2001-11-08 Sankyo Company, Limited 13-substituted milbemycin derivatives, their preparation and their use against insects and other pests
HUP0401677A2 (hu) * 2001-10-25 2004-12-28 Sankyo Lifetech Company, Limited Parazitaellenes készítmény és alkalmazása
US7001889B2 (en) * 2002-06-21 2006-02-21 Merial Limited Anthelmintic oral homogeneous veterinary pastes
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US8362086B2 (en) 2005-08-19 2013-01-29 Merial Limited Long acting injectable formulations
US20080027011A1 (en) * 2005-12-20 2008-01-31 Hassan Nached Homogeneous paste and gel formulations
EP1849363A1 (de) * 2006-03-09 2007-10-31 Cheminova A/S Synergistische Kombinationen aus Glutaminsäure- und GABA-aktivierten Chloridkanälen agonistischen Pestiziden und mindestens eins von Vitamin E und Niacin
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KR100794258B1 (ko) * 2006-12-26 2008-01-11 삼성중공업 주식회사 조파저항 감소를 위한 선박의 트랜섬 선미구조
US8088801B2 (en) 2007-05-15 2012-01-03 Merial Limited Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
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EP2237774B1 (de) 2007-12-21 2016-06-22 Merial Limited Verwendung von 6-halogen-(1,2,4)-triazolo-(1,5-a)-pyrimidin-verbindungen zur bekämpfung von schädlingen in und auf tieren
US20100022469A1 (en) * 2008-06-24 2010-01-28 Majid Razzak Anthelminthic formulations
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US8450357B2 (en) 2008-11-19 2013-05-28 Merial Limited Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof
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WO2013074892A1 (en) 2011-11-17 2013-05-23 Merial Limited Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof
BR112014013371B1 (pt) 2011-12-02 2020-04-07 Merial Ltd formulações de moxidectina injetável de ação prolongada e novas formas de cristal de moxidectina
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US4093629A (en) * 1977-04-11 1978-06-06 Merck & Co., Inc. Derivatives of antibiotic substance milbemycin and processes therefor
NZ188459A (en) * 1977-10-03 1982-09-07 Merck & Co Inc Derivatives of c-076 compounds and pesticidal compositions
US4201861A (en) * 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
PH15982A (en) * 1977-10-03 1983-05-18 Merck & Co Inc Selective hydrogenation producta of c-076 compounds and derivatives thereof
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds
US4423209A (en) * 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
JPS59108785A (ja) * 1982-11-25 1984-06-23 Sankyo Co Ltd ミルベマイシン類の5−オキシム誘導体
US4579864A (en) * 1984-06-11 1986-04-01 Merck & Co., Inc. Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
AU574852B2 (en) * 1984-10-26 1988-07-14 Sankyo Company Limited 13 - acyloxy - 5 - ketomilbemycin derivatives and preparation of 13 - hydroxy - 5 - ketomilbemycin derivatives
GB2168345B (en) * 1984-12-14 1988-05-25 Ciba Geigy Ag Pesticidal 13b-substituted milbemycin derivatives
JPS6289685A (ja) * 1985-05-31 1987-04-24 Sankyo Co Ltd 13−ハロゲンミルベマイシン誘導体
EP0246739B1 (de) * 1986-03-25 1991-01-23 Sankyo Company Limited Makrolide Verbindungen, ihre Herstellung und Verwendung
RU2086552C1 (ru) * 1991-12-18 1997-08-10 Санкио Компани Лимитед Производные 13-(замещенного тио)ацетоксимилбемицина, способ их получения, инсектицидная композиция и способ защиты растений

Also Published As

Publication number Publication date
AU592858B2 (en) 1990-01-25
AR243191A1 (es) 1993-07-30
NZ219759A (en) 1990-04-26
DK170046B1 (da) 1995-05-08
AU7060787A (en) 1987-10-01
IL81997A0 (en) 1987-10-20
FI95707C (fi) 1996-03-11
HUT43846A (en) 1987-12-28
EP0342710A1 (de) 1989-11-23
CN1071430A (zh) 1993-04-28
EP0342710B1 (de) 1993-05-19
FI95707B (fi) 1995-11-30
KR870008891A (ko) 1987-10-21
IE870760L (en) 1987-09-25
KR940009790B1 (ko) 1994-10-17
ATE89560T1 (de) 1993-06-15
US5405867A (en) 1995-04-11
RU2024527C1 (ru) 1994-12-15
PT84549B (pt) 1989-11-10
CN87103559A (zh) 1988-01-27
BR8701302A (pt) 1987-12-22
DK149987A (da) 1987-09-26
RU2049785C1 (ru) 1995-12-10
CN1022834C (zh) 1993-11-24
DE3767560D1 (de) 1991-02-28
US4963582A (en) 1990-10-16
EP0246739A3 (en) 1988-03-16
HU198496B (en) 1989-10-30
CN1028864C (zh) 1995-06-14
GR3001548T3 (en) 1992-11-23
FI871294A (fi) 1987-09-26
PT84549A (pt) 1987-04-01
ES2019932B3 (es) 1991-07-16
DE3785936T2 (de) 1993-08-26
ES2057027T3 (es) 1994-10-16
IL81997A (en) 1994-11-28
FI871294A0 (fi) 1987-03-24
DK149987D0 (da) 1987-03-24
EP0246739A2 (de) 1987-11-25
EP0246739B1 (de) 1991-01-23
IE61347B1 (en) 1994-11-02
CA1317935C (en) 1993-05-18

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