ES2155172T3 - Derivados milbemicina 5-oxima 13-sustituidos, su preparacion y su uso contra insectos y otras plagas. - Google Patents

Derivados milbemicina 5-oxima 13-sustituidos, su preparacion y su uso contra insectos y otras plagas.

Info

Publication number
ES2155172T3
ES2155172T3 ES96307092T ES96307092T ES2155172T3 ES 2155172 T3 ES2155172 T3 ES 2155172T3 ES 96307092 T ES96307092 T ES 96307092T ES 96307092 T ES96307092 T ES 96307092T ES 2155172 T3 ES2155172 T3 ES 2155172T3
Authority
ES
Spain
Prior art keywords
sup
rent
cyclalquil
sub
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96307092T
Other languages
English (en)
Inventor
Kazuo Sato
Akio Saito
Toshimitsu Toyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of ES2155172T3 publication Critical patent/ES2155172T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/24—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with two or more hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pest Control & Pesticides (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

COMPUESTOS DE FORMULA (I): EN DONDE: R 1 ES METILO, ETILO, ISOPROPILO O SEC-BUTILO; X ES CARBONILO O METILENO; Z ES =C=(R{SUP,2}){SUB,2} O =C=(CH{SUB,2}){SUB,M} (EN DONDE R{SUP,2} ES ALQUILO, Y M ES UN ENTERO DE 2 A 5); N ES 0 O 1; R{SUP,3} ES NITRO, AMINO, ALQUILAMINO, DIALQUILAMINO, ALCOXI, ALCOXIALCOXI, O UN GRUPO (III), (IV), (V), (VI), (VII), (VIII) O (IX): (EN DONDE : R{SUP,4}REPRESENTA: ALQUILO; ALQUILO SUSTITUIDO; CICLOALQUILO DE 3 A 6 ATOMOS DE CARBONO; CICLOALQUILO SUSTITUIDO; ALQUENILO; ALQUINILO; ARILO CARBOCICLICO O HETEROCICLICO; R{SUP,5} ES UN ATOMO DE HIDROGENO O ALQUILO; R{SUP,6} REPRESENTA: HIDROGENO; ALQUILO; O CICLOALQUILO; R{SUP,7} REPRESENTA: ALQUILO; CICLOALQUILO; ARILO CARBOCICLICO; O ARALQUILO; O R{SUP,6} Y R{SUP,7}, JUNTO CON EL ATOMO DE NITROGENO AL CUAL ESTAN UNIDOS, ESTAN FUSIONADOS FORMANDO UN ANILLO HETEROCICLICO; Y ES OXIGENO O AZUFRE; R ES 1,2 O 3; Q ES METILENO O CARBONILO; R{SUP,8} ES: ALQUILO O ARILO CARBOCICLICO; R{SUP,9} ES: ALQUILO; CICLOALQUILO; ARILOCARBOCICLICO; O ARALQUILO; R{SUP,10} ES HETEROCICLICO; Y R{SUP,11} ES ALQUILO). DICHOS COMPUESTON PRESENTAN ACTIVIDADES ACARICIDAS, INSECTICIDAS Y ANTIHELMINTICAS UTILES.
ES96307092T 1995-09-29 1996-09-27 Derivados milbemicina 5-oxima 13-sustituidos, su preparacion y su uso contra insectos y otras plagas. Expired - Lifetime ES2155172T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP25296595 1995-09-29

Publications (1)

Publication Number Publication Date
ES2155172T3 true ES2155172T3 (es) 2001-05-01

Family

ID=17244627

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96307092T Expired - Lifetime ES2155172T3 (es) 1995-09-29 1996-09-27 Derivados milbemicina 5-oxima 13-sustituidos, su preparacion y su uso contra insectos y otras plagas.

Country Status (19)

Country Link
US (1) US5861429A (es)
EP (1) EP0765879B1 (es)
KR (1) KR100300376B1 (es)
AT (1) ATE199154T1 (es)
AU (1) AU707152B2 (es)
CA (1) CA2186650A1 (es)
CZ (1) CZ288178B6 (es)
DE (1) DE69611773T2 (es)
DK (1) DK0765879T3 (es)
ES (1) ES2155172T3 (es)
GR (1) GR3035565T3 (es)
HK (1) HK1003937A1 (es)
HU (1) HU225226B1 (es)
IL (1) IL119321A (es)
NO (1) NO317090B1 (es)
NZ (1) NZ299460A (es)
PT (1) PT765879E (es)
RU (1) RU2128181C1 (es)
ZA (1) ZA968183B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000043371A2 (en) 1999-01-22 2000-07-27 Elan Pharmaceuticals, Inc. Fused ring heteroaryl and heterocyclic compounds which inhibit leukocyte adhesion mediated by vla-4
EP1144388B1 (en) 1999-01-22 2010-01-13 Elan Pharmaceuticals, Inc. Acyl derivatives which treat vla-4 related disorders
US6465513B1 (en) 1999-01-22 2002-10-15 Elan Pharmaceuticals, Inc. Multicyclic compounds which inhibit leukocyte adhesion mediated by VLA-4
US6436904B1 (en) * 1999-01-25 2002-08-20 Elan Pharmaceuticals, Inc. Compounds which inhibit leukocyte adhesion mediated by VLA-4
DE60009883T2 (de) 1999-03-01 2005-04-07 Elan Pharmaceuticals, Inc., San Francisco Alpha-aminoessigsäure derivate als alpha 4 beta 7- rezeptor antagonisten
CN1247607C (zh) 2000-04-27 2006-03-29 三共生命科技株式会社 13－取代的米尔螨素衍生物,它们的制备方法及其杀昆虫和其它有害动物的用途
NZ532977A (en) * 2001-10-25 2007-01-26 Sankyo Lifetech Company Ltd Anthelmintic composition
TW200307671A (en) * 2002-05-24 2003-12-16 Elan Pharm Inc Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins
TWI281470B (en) * 2002-05-24 2007-05-21 Elan Pharm Inc Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins
JP4373080B2 (ja) * 2002-12-24 2009-11-25 三井化学アグロ株式会社 ミルベマイシン類の精製法
BRPI0507428B8 (pt) 2004-02-05 2021-07-27 Nippon Catalytic Chem Ind agente particulado para absorção de água, método de produção do mesmo e artigo absorvente
TWI344469B (en) 2005-04-07 2011-07-01 Nippon Catalytic Chem Ind Polyacrylic acid (salt) water-absorbent resin, production process thereof, and acrylic acid used in polymerization for production of water-absorbent resin
JP5081828B2 (ja) * 2005-09-29 2012-11-28 エラン ファーマシューティカルズ，インコーポレイテッド Ｖｌａ−４によって媒介される白血球粘着を阻害するカルバメート化合物
NZ567270A (en) * 2005-09-29 2011-06-30 Elan Pharm Inc Pyrimidinyl amide compounds which inhibit leukocyte adhesion mediated by VLA-4
TWI394789B (zh) 2005-12-22 2013-05-01 Nippon Catalytic Chem Ind 吸水性樹脂組成物及其製造方法、吸收性物品
KR20080100271A (ko) * 2006-02-27 2008-11-14 엘란 파마슈티칼스, 인크. Ｖｌａ-4에 의해 매개되는 백혈구 부착을 억제하는 피리미디닐 술폰아미드 화합물
EP1837348B9 (en) 2006-03-24 2020-01-08 Nippon Shokubai Co.,Ltd. Water-absorbing resin and method for manufacturing the same
JP2012525336A (ja) * 2009-04-27 2012-10-22 エラン ファーマシューティカルズ，インコーポレイテッド α−４インテグリンのピリジノンアンタゴニスト
US8952116B2 (en) 2009-09-29 2015-02-10 Nippon Shokubai Co., Ltd. Particulate water absorbent and process for production thereof

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950360A (en) * 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
US4201861A (en) * 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
US4206205A (en) * 1977-10-03 1980-06-03 Merck & Co., Inc. Monosaccharide and aglycone derivatives of C-076
US4171314A (en) * 1977-12-19 1979-10-16 Merck & Co., Inc. 13-Halo and 13-deoxy C-076 compounds
US4173571A (en) * 1977-12-19 1979-11-06 Merck & Co., Inc. 13-Halo and 13-deoxy derivatives of C-076 compounds
US4203976A (en) * 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
JPS5632481A (en) * 1979-08-23 1981-04-01 Sankyo Co Ltd Antibiotic b-41d, its preparation, and acaricide and anthelminthic agent and repellent containing the same as active constituent
US4289760A (en) * 1980-05-02 1981-09-15 Merck & Co., Inc. 23-Keto derivatives of C-076 compounds
US4457920A (en) * 1981-09-03 1984-07-03 Merck & Co., Inc. 4a-Substituted avermectin compounds
US4423209A (en) * 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
JPS59108785A (ja) * 1982-11-25 1984-06-23 Sankyo Co Ltd ミルベマイシン類の５−オキシム誘導体
US4579864A (en) * 1984-06-11 1986-04-01 Merck & Co., Inc. Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
US4547491A (en) * 1984-07-18 1985-10-15 Merck & Co., Inc. C-8A-Oxo-avermectin and milbemycin derivatives, pharmaceutical compositions and method of use
JPS6289685A (ja) * 1985-05-31 1987-04-24 Sankyo Co Ltd １３−ハロゲンミルベマイシン誘導体
RU2024527C1 (ru) * 1986-03-25 1994-12-15 Санкио Компани Лимитед Способ получения макролидных соединений
US5428034A (en) * 1988-09-02 1995-06-27 Sankyo Co., Ltd. Milbemycin derivatives, their preparation and their use
KR0171426B1 (ko) * 1991-12-18 1999-02-01 가와무라 요시부미 13-(치환 티오) 아세톡시밀베마이신 유도체, 그의 제조방법 및 농화학적 용도
US5614470A (en) * 1994-04-01 1997-03-25 Sankyo Company, Limited 13-substituted milbemycin derivatives, their preparation and their use
AU3935495A (en) * 1994-11-24 1996-06-17 Sankyo Company Limited 13-etherified milbemycin derivative with insecticidal activity

Also Published As

Publication number Publication date
HUP9602678A1 (en) 1997-11-28
NO964090D0 (no) 1996-09-27
NZ299460A (en) 1997-12-19
PT765879E (pt) 2001-05-31
CA2186650A1 (en) 1997-03-30
CZ288178B6 (en) 2001-05-16
HU225226B1 (en) 2006-08-28
IL119321A0 (en) 1996-12-05
ATE199154T1 (de) 2001-02-15
EP0765879B1 (en) 2001-02-14
HK1003937A1 (en) 1998-11-13
DE69611773T2 (de) 2001-09-13
KR100300376B1 (ko) 2001-10-22
GR3035565T3 (en) 2001-06-29
HU9602678D0 (en) 1996-11-28
DK0765879T3 (da) 2001-03-19
RU2128181C1 (ru) 1999-03-27
US5861429A (en) 1999-01-19
NO317090B1 (no) 2004-08-02
CZ286296A3 (en) 1997-04-16
NO964090L (no) 1997-04-01
IL119321A (en) 2001-05-20
DE69611773D1 (de) 2001-03-22
AU6586196A (en) 1997-04-10
EP0765879A1 (en) 1997-04-02
KR970015592A (ko) 1997-04-28
AU707152B2 (en) 1999-07-01
ZA968183B (en) 1997-04-25

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