DE3769872D1 - Herstellung von rekombinantem protein. - Google Patents

Herstellung von rekombinantem protein.

Info

Publication number
DE3769872D1
DE3769872D1 DE8787109276T DE3769872T DE3769872D1 DE 3769872 D1 DE3769872 D1 DE 3769872D1 DE 8787109276 T DE8787109276 T DE 8787109276T DE 3769872 T DE3769872 T DE 3769872T DE 3769872 D1 DE3769872 D1 DE 3769872D1
Authority
DE
Germany
Prior art keywords
production
recombinant protein
lipoprotein
culturing
enhanced
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE8787109276T
Other languages
English (en)
Inventor
Sham Yuen Chan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25384571&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3769872(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Miles Inc filed Critical Miles Inc
Application granted granted Critical
Publication of DE3769872D1 publication Critical patent/DE3769872D1/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE8787109276T 1986-07-11 1987-06-27 Herstellung von rekombinantem protein. Revoked DE3769872D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88441286A 1986-07-11 1986-07-11

Publications (1)

Publication Number Publication Date
DE3769872D1 true DE3769872D1 (de) 1991-06-13

Family

ID=25384571

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787109276T Revoked DE3769872D1 (de) 1986-07-11 1987-06-27 Herstellung von rekombinantem protein.

Country Status (5)

Country Link
EP (1) EP0254076B1 (de)
JP (1) JPH0630610B2 (de)
AT (1) ATE63335T1 (de)
DE (1) DE3769872D1 (de)
DK (1) DK359487A (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198349A (en) * 1986-01-03 1993-03-30 Genetics Institute, Inc. Method for producing factor VIII:C and analogs
JP2525022B2 (ja) * 1986-01-03 1996-08-14 ジェネティックス・インスチチュ−ト・インコ−ポレ−テッド ▲ＶＩＩＩ▼：ｃ因子型タンパク質の改良生産方法
US5595886A (en) * 1986-01-27 1997-01-21 Chiron Corporation Protein complexes having Factor VIII:C activity and production thereof
US6060447A (en) * 1987-05-19 2000-05-09 Chiron Corporation Protein complexes having Factor VIII:C activity and production thereof
JP3045307B2 (ja) * 1989-08-11 2000-05-29 ザイモジェネティクス，インコーポレイティド 活性化プロテインｃを生成するための細胞培養法
FR2657884B1 (fr) * 1990-02-05 1994-09-02 Tm Innovation Procede pour la preparation du facteur viii humain et d'analogues du facteur viii.
DK53792D0 (da) * 1992-04-24 1992-04-24 Novo Nordisk As Fremgangsmaade til fremstilling af proteiner
EP0679192A1 (de) * 1992-11-17 1995-11-02 Novo Nordisk A/S Verbesserte rekombinante produktion von proteinen welche faktor viii:c aktivität haben
US5952198A (en) * 1995-05-04 1999-09-14 Bayer Corporation Production of recombinant Factor VIII in the presence of liposome-like substances of mixed composition
US6358703B1 (en) 1998-12-10 2002-03-19 Bayer Corporation Expression system for factor VIII
EP1707634A1 (de) 2005-03-29 2006-10-04 Octapharma AG Verfahren zur Isolierung von rekombinant hergestellten Proteinen
EP1739179A1 (de) 2005-06-30 2007-01-03 Octapharma AG Serumfreie stabile Transfektion und Produktion von rekombinanten humanen Proteinen in humanen Zelllinien
EP1988101A1 (de) * 2007-05-04 2008-11-05 Novo Nordisk A/S Verbesserung von Faktor-VIII-Polypeptid-Titern in Zellkulturen
WO2011095604A1 (en) 2010-02-04 2011-08-11 Octapharma Biopharmaceuticals Gmbh Half-life prolongation of proteins

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125409B (en) 1982-08-04 1985-11-13 Nat Res Dev Genetic engineering
EP0162067B1 (de) 1983-10-28 1992-07-15 Genetics Institute, Inc. Herstellung des faktors viii und damit verwandte erzeugnisse
DE3588242T2 (de) 1984-01-12 2004-03-11 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Für Faktor-VIIIc kodierende DNA-Sequenzen und verwandte DNA-Konstruktionen
ZA852099B (en) 1984-03-26 1985-12-24 Meloy Lab Recombinant factor viii-c.
FI86885C (fi) * 1984-04-20 1992-10-26 Genentech Inc Foerfarande foer framstaellning av human rekombinantfaktor viii och nukleinsyrasekvenser och vektorer anvaend daertill
JPS6163283A (ja) * 1984-09-03 1986-04-01 Teijin Ltd ハイブリ−ド−マの培養方法

Also Published As

Publication number Publication date
JPS6342699A (ja) 1988-02-23
DK359487A (da) 1988-01-12
DK359487D0 (da) 1987-07-10
ATE63335T1 (de) 1991-05-15
EP0254076A1 (de) 1988-01-27
JPH0630610B2 (ja) 1994-04-27
EP0254076B1 (de) 1991-05-08

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation