DE3766401D1 - Benzodiazepinderivate und ihre herstellung und verwendung. - Google Patents

Benzodiazepinderivate und ihre herstellung und verwendung.

Info

Publication number
DE3766401D1
DE3766401D1 DE8787102733T DE3766401T DE3766401D1 DE 3766401 D1 DE3766401 D1 DE 3766401D1 DE 8787102733 T DE8787102733 T DE 8787102733T DE 3766401 T DE3766401 T DE 3766401T DE 3766401 D1 DE3766401 D1 DE 3766401D1
Authority
DE
Germany
Prior art keywords
benzodiazepine derivatives
production
chem
alkyl
nootropics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787102733T
Other languages
English (en)
Inventor
Frank Waetjen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Ferrosan ApS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrosan ApS filed Critical Ferrosan ApS
Application granted granted Critical
Publication of DE3766401D1 publication Critical patent/DE3766401D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Power Steering Mechanism (AREA)
DE8787102733T 1986-04-16 1987-02-26 Benzodiazepinderivate und ihre herstellung und verwendung. Expired - Lifetime DE3766401D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK174086A DK174086D0 (da) 1986-04-16 1986-04-16 Nye benzodiazepinderivater samt fremgangsmaade til fremstilling af samme

Publications (1)

Publication Number Publication Date
DE3766401D1 true DE3766401D1 (de) 1991-01-10

Family

ID=8107685

Family Applications (2)

Application Number Title Priority Date Filing Date
DE198787102733T Pending DE241682T1 (de) 1986-04-16 1987-02-26 Benzodiazepinderivate und ihre herstellung und verwendung.
DE8787102733T Expired - Lifetime DE3766401D1 (de) 1986-04-16 1987-02-26 Benzodiazepinderivate und ihre herstellung und verwendung.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE198787102733T Pending DE241682T1 (de) 1986-04-16 1987-02-26 Benzodiazepinderivate und ihre herstellung und verwendung.

Country Status (19)

Country Link
US (1) US4772599A (de)
EP (1) EP0241682B1 (de)
JP (1) JPH07116195B2 (de)
KR (1) KR940009784B1 (de)
AT (1) ATE58737T1 (de)
AU (1) AU588994B2 (de)
CA (1) CA1293724C (de)
DE (2) DE241682T1 (de)
DK (1) DK174086D0 (de)
ES (1) ES2037673T3 (de)
FI (1) FI87458C (de)
GR (1) GR3001160T3 (de)
IE (1) IE60488B1 (de)
IL (1) IL82117A (de)
NO (1) NO164655C (de)
NZ (1) NZ219915A (de)
PH (1) PH22406A (de)
PT (1) PT84690B (de)
ZA (1) ZA872630B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU594676B2 (en) * 1985-05-17 1990-03-15 Novo Nordisk A/S Oxadiazolyl imidazobenaodiazepine compound, pharmaceutical composition containing said compound, method of preparing said compound and method of treating a central nervous system ailment
US4622320A (en) * 1985-05-17 1986-11-11 As Ferrosan Oxadiazolylimidazobenzodiazepine, compositions, and method
FI880814A (fi) * 1987-03-10 1988-09-11 Hoffmann La Roche Imidazodiazepin-derivat.
GB8720414D0 (en) * 1987-08-28 1987-10-07 Roussel Lab Ltd Chemical compounds
CA2015336A1 (en) * 1989-05-19 1990-11-19 F. Hoffmann-La Roche Ag Imidazodiazepines for the treatment of neurological symptoms
US4904654A (en) * 1989-07-26 1990-02-27 Merck & Co., Inc. 7-chloro-5,6-dihydro-3-(5-(2-hydroxy-isopropyl)-1,2,4-oxadiazol-3-yl)-5-methyl-6-oxo-4H-imidazo[1,5a][1,4]benzodiazepine
CA2143246C (en) * 1994-03-16 2000-08-22 Thierry Godel Imidazodiazepines
US5438035A (en) * 1994-06-24 1995-08-01 American Cyanamid Company Methods for controlling undesirable plant species with benzodiazepine compounds
US5706829A (en) * 1996-06-06 1998-01-13 Creighton University Method for treating neurocardiogenic syncope
KR100283474B1 (ko) * 1999-01-18 2001-02-15 박호군 Ｎ₂ｓ₂리간드가 포함된 플루마제닐 유도체 및 그의 제조방법
TWI239333B (en) 2000-11-16 2005-09-11 Hoffmann La Roche Benzodiazepine derivatives as GABA A receptor modulators
CN101039678B (zh) * 2004-10-12 2011-06-15 弗·哈夫曼-拉罗切有限公司 用于治疗认知障碍的咪唑并[1,5-a]***并[1,5-d]苯并二氮杂䓬衍生物
RU2007112940A (ru) * 2004-10-20 2008-11-27 Ф.Хоффманн-Ля Рош Аг (Ch) Производные имидазобензодиазепина
CN101084220B (zh) * 2004-10-20 2010-12-15 弗·哈夫曼-拉罗切有限公司 卤素取代的苯并二氮杂*衍生物
ES2307230T3 (es) * 2004-12-14 2008-11-16 F. Hoffmann-La Roche Ag Imidazo-benzodiacepinas tetraciclicas como moduladores de los receptores gaba.
WO2009024325A2 (en) * 2007-08-20 2009-02-26 Evotec Neurosciences Gmbh Treatment of sleep disorders
US20090054412A1 (en) * 2007-08-20 2009-02-26 John Alan Kemp Treatment of Sleep Disorders

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1143728A (en) * 1979-10-04 1983-03-29 Max Gerecke Imidazodiazepine derivatives
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
CA1185602A (en) * 1981-02-27 1985-04-16 Emilio Kyburz Imidazodiazepines
MC1528A1 (fr) * 1982-07-21 1984-04-13 Hoffmann La Roche Imidazobenzodiazepines
DK151808C (da) * 1982-11-16 1988-06-20 Ferrosan As Analogifremgangsmaade til fremstilling af oxadiazolylimidazo-oe1,4aa-benzodiazepinderivater
IL74070A (en) * 1984-01-19 1988-12-30 Hoffmann La Roche Imidazodiazepine derivatives,their manufacture and pharmaceutical compositions containing them
CA1259612A (en) * 1985-02-28 1989-09-19 Emilio Kyburz Imidazodiazepine derivatives
AU587802B2 (en) * 1985-03-08 1989-08-31 Ferrosan A/S Novel oxadiazolyl imidazobenzodiazepine derivatives and methods of preparing such compounds
US4622320A (en) * 1985-05-17 1986-11-11 As Ferrosan Oxadiazolylimidazobenzodiazepine, compositions, and method
DE3661197D1 (en) * 1985-05-17 1988-12-22 Ferrosan As Oxadiazolylimidazobenzodiazepines, process for their preparation and pharmaceutical compositions
DK476885D0 (da) * 1985-10-17 1985-10-17 Ferrosan As Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf
AU594676B2 (en) * 1985-05-17 1990-03-15 Novo Nordisk A/S Oxadiazolyl imidazobenaodiazepine compound, pharmaceutical composition containing said compound, method of preparing said compound and method of treating a central nervous system ailment

Also Published As

Publication number Publication date
PT84690B (pt) 1989-11-30
IE60488B1 (en) 1994-07-27
NO164655B (no) 1990-07-23
KR870010052A (ko) 1987-11-30
ES2037673T3 (es) 1993-07-01
DK174086D0 (da) 1986-04-16
FI871615A0 (fi) 1987-04-13
PT84690A (en) 1987-05-01
FI871615A (fi) 1987-10-17
NO164655C (no) 1990-10-31
GR3001160T3 (en) 1992-06-30
JPH07116195B2 (ja) 1995-12-13
IL82117A (en) 1992-03-29
AU588994B2 (en) 1989-09-28
ZA872630B (en) 1987-10-02
NO871459D0 (no) 1987-04-07
FI87458C (fi) 1993-01-11
NZ219915A (en) 1989-04-26
ATE58737T1 (de) 1990-12-15
EP0241682B1 (de) 1990-11-28
JPS62249985A (ja) 1987-10-30
EP0241682A3 (en) 1988-10-26
DE241682T1 (de) 1988-02-25
US4772599A (en) 1988-09-20
IL82117A0 (en) 1987-10-30
KR940009784B1 (ko) 1994-10-17
NO871459L (no) 1987-10-19
CA1293724C (en) 1991-12-31
AU7158387A (en) 1987-10-22
IE870981L (en) 1987-10-16
PH22406A (en) 1988-08-26
EP0241682A2 (de) 1987-10-21
FI87458B (fi) 1992-09-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NOVO NORDISK A/S, BAGSVAERD, DK

8328 Change in the person/name/address of the agent

Free format text: GRUENECKER, A., DIPL.-ING. KINKELDEY, H., DIPL.-ING. DR.-ING. STOCKMAIR, W., DIPL.-ING. DR.-ING. AE.E. CAL TECH SCHUMANN, K., DIPL.-PHYS. DR.RER.NAT. JAKOB, P., DIPL.-ING. BEZOLD, G., DIPL.-CHEM. DR.RER.NAT. MEISTER, W., DIPL.-ING. HILGERS, H., DIPL.-ING. MEYER-PLATH, H., DIPL.-ING. DR.-ING. EHNOLD, A., DIPL.-ING. SCHUSTER, T., DIPL.-PHYS. GOLDBACH, K., DIPL.-ING.DR.-ING. AUFENANGER, M., DIPL.-ING. KLITZSCH, G., DIPL.-ING., PAT.-ANWAELTE, 8000 MUENCHEN

8339 Ceased/non-payment of the annual fee