DE3675812D1 - Carbostyrilderivate und ihre salze, verfahren zu ihrer herstellung und diese enthaltende cardiotonische zubereitungen. - Google Patents

Carbostyrilderivate und ihre salze, verfahren zu ihrer herstellung und diese enthaltende cardiotonische zubereitungen.

Info

Publication number
DE3675812D1
DE3675812D1 DE8686302768T DE3675812T DE3675812D1 DE 3675812 D1 DE3675812 D1 DE 3675812D1 DE 8686302768 T DE8686302768 T DE 8686302768T DE 3675812 T DE3675812 T DE 3675812T DE 3675812 D1 DE3675812 D1 DE 3675812D1
Authority
DE
Germany
Prior art keywords
salts
production
preparations containing
carbostyril derivatives
cardiotonic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686302768T
Other languages
English (en)
Inventor
Atsushi Abiko
Takafumi Fujioka
Kazuyuki Nakagawa
Kazumi Kondo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP61066889A external-priority patent/JPH07116157B2/ja
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3675812D1 publication Critical patent/DE3675812D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8686302768T 1985-04-12 1986-04-14 Carbostyrilderivate und ihre salze, verfahren zu ihrer herstellung und diese enthaltende cardiotonische zubereitungen. Expired - Fee Related DE3675812D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP7898085 1985-04-12
JP22749385 1985-10-11
JP61066889A JPH07116157B2 (ja) 1985-04-12 1986-03-24 カルボスチリル誘導体

Publications (1)

Publication Number Publication Date
DE3675812D1 true DE3675812D1 (de) 1991-01-10

Family

ID=27299295

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686302768T Expired - Fee Related DE3675812D1 (de) 1985-04-12 1986-04-14 Carbostyrilderivate und ihre salze, verfahren zu ihrer herstellung und diese enthaltende cardiotonische zubereitungen.

Country Status (3)

Country Link
US (1) US4845100A (de)
EP (1) EP0202760B1 (de)
DE (1) DE3675812D1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4886809A (en) * 1986-07-31 1989-12-12 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and salts thereof
JPH0696555B2 (ja) * 1986-07-31 1994-11-30 大塚製薬株式会社 カルボスチリル誘導体
GB8630702D0 (en) * 1986-12-23 1987-02-04 Wellcome Found Quinoline compound
US5166160A (en) * 1986-12-23 1992-11-24 Burroughs Wellcome Co. Quinoline compound
JPH06239858A (ja) * 1993-02-16 1994-08-30 Otsuka Pharmaceut Co Ltd 末梢血管拡張剤
AU2001293847B2 (en) * 2000-10-02 2007-05-24 Janssen Pharmaceutica N.V. Metabotropic glutamate receptor antagonists
ES2462240T3 (es) * 2006-02-28 2014-05-22 Dart Neuroscience (Cayman) Ltd Piperazinas terapéuticas como inhibidores de PDE4
US8927546B2 (en) 2006-02-28 2015-01-06 Dart Neuroscience (Cayman) Ltd. Therapeutic piperazines
ITMI20061581A1 (it) * 2006-08-04 2008-02-05 Univ Bari Ligandi del recettore beta-3 adrenergico e loro uso in terapia
WO2012061597A1 (en) * 2010-11-03 2012-05-10 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer, National Institutes Of Health Alpha-glucosidase binders and methods of their use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4022784A (en) * 1974-01-31 1977-05-10 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-substituted-carbostyril and -3,4-dihydrocarbostyril derivatives
US4026897A (en) * 1974-01-31 1977-05-31 Otsuka Pharmaceutical Company 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-hydroxycarbostyril derivatives
JPS5777676A (en) * 1980-10-31 1982-05-15 Otsuka Pharmaceut Co Ltd Carbostyril derivative
FI77852C (fi) * 1981-02-17 1989-05-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av nya, saosom hjaertmediciner anvaendbara substituerade amid- och (maettad heterocykel)karbonylkarbostyrilderivat.
DE3108873A1 (de) * 1981-03-09 1982-09-16 Basf Ag, 6700 Ludwigshafen Dichlorchinolinderivate, ihre herstellung, ihre verwendung als herbizide und mittel dafuer
JPS58148817A (ja) * 1982-02-26 1983-09-05 Otsuka Pharmaceut Co Ltd 強心剤
JPS58148861A (ja) * 1982-02-26 1983-09-05 Otsuka Pharmaceut Co Ltd カルボスチリル誘導体
DE3233089A1 (de) * 1982-09-07 1984-03-08 Basf Ag, 6700 Ludwigshafen Chinolinderivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses

Also Published As

Publication number Publication date
EP0202760A3 (en) 1988-01-13
EP0202760A2 (de) 1986-11-26
EP0202760B1 (de) 1990-11-28
US4845100A (en) 1989-07-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee