DE3665711D1 - Novel guanidinomethylbenzoic acid derivatives - Google Patents

Novel guanidinomethylbenzoic acid derivatives

Info

Publication number
DE3665711D1
DE3665711D1 DE8686110197T DE3665711T DE3665711D1 DE 3665711 D1 DE3665711 D1 DE 3665711D1 DE 8686110197 T DE8686110197 T DE 8686110197T DE 3665711 T DE3665711 T DE 3665711T DE 3665711 D1 DE3665711 D1 DE 3665711D1
Authority
DE
Germany
Prior art keywords
novel
acid derivatives
guanidinomethylbenzoic acid
guanidinomethylbenzoic
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8686110197T
Other languages
English (en)
Inventor
Toshio Satoh
Hitoshi Matsumoto
Hisao Kakegawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Med-Creat KK
Original Assignee
Med-Creat KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Med-Creat KK filed Critical Med-Creat KK
Application granted granted Critical
Publication of DE3665711D1 publication Critical patent/DE3665711D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
DE8686110197T 1985-07-30 1986-07-24 Novel guanidinomethylbenzoic acid derivatives Expired DE3665711D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP60166903A JPS6229566A (ja) 1985-07-30 1985-07-30 新規グアニジノメチル安息香酸誘導体

Publications (1)

Publication Number Publication Date
DE3665711D1 true DE3665711D1 (de) 1989-10-26

Family

ID=15839768

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686110197T Expired DE3665711D1 (de) 1985-07-30 1986-07-24 Novel guanidinomethylbenzoic acid derivatives

Country Status (7)

Country Link
US (1) US4732916A (de)
EP (1) EP0218027B1 (de)
JP (1) JPS6229566A (de)
AT (1) ATE46501T1 (de)
DE (1) DE3665711D1 (de)
ES (1) ES2001341A6 (de)
PT (1) PT83104B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63126860A (ja) * 1986-11-17 1988-05-30 Nippon Haipotsukusu:Kk グアニジノメチル安息香酸誘導体
US4948891A (en) * 1988-05-24 1990-08-14 Pfizer Inc. Benzamide protease inhibitors
US4970318A (en) * 1988-05-24 1990-11-13 Pfizer Inc. Aromatic and heterocyclic carboxamide derivatives as antineoplastic agents
US4948901A (en) * 1988-05-24 1990-08-14 Pfizer Inc. Benzamide protease inhibitors
US4874864A (en) * 1988-05-24 1989-10-17 Pfizer Inc. Benzamide protease inhibitors
US5654451B1 (en) * 1993-01-14 2000-02-22 Magainin Pharma Amino acids and peptides having modified c-terminals and modified n-terminals
DE4305536A1 (de) * 1993-02-19 1994-08-25 Asche Ag Verwendung von Enzym-Inhibitoren zur Herstellung eines Arzneimittels
EP1195372A1 (de) * 1994-04-18 2002-04-10 Mitsubishi Pharma Corporation N-Heterozyklisch substitutierte Benzamid Deriviate mit antihypertensiver Wirkung
TW499412B (en) 1996-11-26 2002-08-21 Dimensional Pharm Inc Aminoguanidines and alkoxyguanidines as protease inhibitors
DZ3415A1 (fr) 2000-08-31 2002-03-07 Chiron Corp Guanidinobenzamides comme mc4-r agonistes.
DE60216747T2 (de) * 2001-04-09 2007-10-04 Novartis Vaccines and Diagnostics, Inc., Emeryville Guanidinoverbindungen als melanocortin-4-rezeptor (mc4-r) agonisten
CN1203055C (zh) * 2001-09-26 2005-05-25 朱德煦 治疗或预防细菌感染的方法和组合物
US20030195187A1 (en) * 2002-02-04 2003-10-16 Chiron Corporation Guanidino compounds
US20030207814A1 (en) * 2002-02-04 2003-11-06 Chiron Corporation Novel guanidinyl derivatives
US20070004743A1 (en) * 2002-02-25 2007-01-04 Xiao Linda L Intranasal administration of mc4-r agonists
US7034033B2 (en) * 2002-05-23 2006-04-25 Chiron Corporation Substituted quinazolinone compounds
AU2004249120B2 (en) * 2003-05-23 2008-07-24 Glaxosmithkline Guanidino-substituted quinazolinone compounds as MC4-R agonists
EP1686996A4 (de) * 2003-11-19 2008-11-12 Novartis Vaccines & Diagnostic Chinazolinon-verbindungen mit verringerter bioakkumulation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3479401A (en) * 1966-06-28 1969-11-18 Merck & Co Inc Guanidinoaryl and guanidinomethylaryl compounds
BE757956A (fr) * 1969-10-24 1971-04-23 Ici Ltd Composes antiviraux
AU541738B2 (en) * 1979-09-20 1985-01-17 Nippon Chemiphar Co. Ltd. Cyclohexane carboxylic acid derivatives
JPS57197256A (en) * 1981-05-28 1982-12-03 Nippon Chemiphar Co Ltd Novel cyclohexanecarboxamide derivative and its preparation

Also Published As

Publication number Publication date
US4732916A (en) 1988-03-22
ATE46501T1 (de) 1989-10-15
JPS6229566A (ja) 1987-02-07
EP0218027A1 (de) 1987-04-15
ES2001341A6 (es) 1988-05-16
PT83104B (en) 1987-12-23
PT83104A (en) 1986-08-01
EP0218027B1 (de) 1989-09-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee