DE3650032T2 - Anticytomegaloviraler menschlicher monoklonaler antikörper und dessen herstellung. - Google Patents

Anticytomegaloviraler menschlicher monoklonaler antikörper und dessen herstellung.

Info

Publication number
DE3650032T2
DE3650032T2 DE3650032T DE3650032T DE3650032T2 DE 3650032 T2 DE3650032 T2 DE 3650032T2 DE 3650032 T DE3650032 T DE 3650032T DE 3650032 T DE3650032 T DE 3650032T DE 3650032 T2 DE3650032 T2 DE 3650032T2
Authority
DE
Germany
Prior art keywords
human monoclonal
anticytomegaloviral
production
monoclonal antibodies
cmv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3650032T
Other languages
English (en)
Other versions
DE3650032D1 (de
Inventor
Yasuhiko Masuho
Toru Sugano
Yoh-Ichi Matsumoto
Shigeki Fujinaga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Publication of DE3650032D1 publication Critical patent/DE3650032D1/de
Application granted granted Critical
Publication of DE3650032T2 publication Critical patent/DE3650032T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/085—Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • C07K16/088—Varicella-zoster virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/085—Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • C07K16/089—Cytomegalovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
DE3650032T 1985-12-06 1986-12-02 Anticytomegaloviraler menschlicher monoklonaler antikörper und dessen herstellung. Expired - Lifetime DE3650032T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP27350485 1985-12-06
PCT/JP1986/000613 WO1987003602A1 (en) 1985-12-06 1986-12-02 Anticytomegaloviral human monoclonal antibody and process for its preparation

Publications (2)

Publication Number Publication Date
DE3650032D1 DE3650032D1 (de) 1994-09-22
DE3650032T2 true DE3650032T2 (de) 1995-03-09

Family

ID=17528811

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3650032T Expired - Lifetime DE3650032T2 (de) 1985-12-06 1986-12-02 Anticytomegaloviraler menschlicher monoklonaler antikörper und dessen herstellung.

Country Status (7)

Country Link
US (1) US5043281A (de)
EP (1) EP0248909B1 (de)
KR (1) KR910000736B1 (de)
AT (1) ATE110084T1 (de)
AU (1) AU590656B2 (de)
DE (1) DE3650032T2 (de)
WO (1) WO1987003602A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5126130A (en) * 1986-11-24 1992-06-30 The Childrens Hospital Incorporated Monoclonal antibodies reactive with specific antigenic sites on human cytomegalovirus glycoprotein a
US5153311A (en) * 1986-11-24 1992-10-06 The Children's Hospital, Incorporated Immunogenic glycoproteins of human cytomegalovirus gCII
US6511665B1 (en) * 1987-11-25 2003-01-28 Immunex Corporation Antibodies to interleukin-1 receptors
AU641121B2 (en) * 1988-01-29 1993-09-16 Chiron Corporation Recombinant CMV neutralizing proteins
SE9201281L (sv) * 1992-04-23 1993-10-24 Bioinvent Int Ab Nya humana monoklonala antikroppar och förfarande för framställning därav
GB9221654D0 (en) * 1992-10-15 1992-11-25 Scotgen Ltd Recombinant human anti-cytomegalovirus antibodies
US5750106A (en) * 1993-01-28 1998-05-12 Novartis Ag Human monoclonal antibodies to cytomegalovirus
WO1996018102A1 (fr) * 1994-12-07 1996-06-13 Fujisawa Pharmaceutical Co., Ltd. Methode de mesure de la concentration en proteines de fixation de fk506
ES2187796T3 (es) * 1996-07-12 2003-06-16 Organon Teknika Bv Reactivo de peptidos que permiten la deteccion de citomegalovirus (cmv) humano.
JPWO2007094423A1 (ja) * 2006-02-15 2009-07-09 株式会社イーベック ヒトサイトメガロウイルスに結合するヒトのモノクローナル抗体並びにその抗原結合部分
US7947274B2 (en) 2007-01-04 2011-05-24 Humabs, LLC. Human cytomegalovirus neutralising antibodies and use thereof
GB0700133D0 (en) 2007-01-04 2007-02-14 Humabs Llc Human cytomegalovirus neutralising antibodies and use thereof
US7763261B2 (en) * 2007-12-19 2010-07-27 Dcb-Usa Llc Anti-human cytomegalovirus antibodies
JP5475774B2 (ja) * 2008-07-16 2014-04-16 インスティテュート フォー リサーチ イン バイオメディシン ヒトサイトメガロウイルス中和抗体およびその使用
SG10201608381SA (en) 2008-07-16 2016-11-29 Inst Research In Biomedicine Human cytomegalovirus neutralizing antibodies and use thereof
RU2542472C2 (ru) 2009-04-01 2015-02-20 Эвек Инкорпорейтед Моноклональное антитело, способное связываться со специфическим прерывистым эпитопом, расположенным в области ad1 гликопротеина gb цитомегаловируса человека, и его антигенсвязывающий фрагмент
WO2010129033A2 (en) * 2009-04-29 2010-11-11 Calmune Corporation Modified antibodies for passive immunotherapy
BR112012015523A2 (pt) 2009-12-23 2017-04-18 4-Antibody Ag membros de ligação do citomegalovirus humano, composição contendo os mesmos, método de tratamento, moléculas de anticorpo, método de produção, molecular de ácido nucléico, célula hospedeira, e, método de neutralização do hcmv.
JP7350716B2 (ja) * 2018-03-27 2023-09-26 森永乳業株式会社 微生物の細胞及び／又はウイルスの測定方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4574116A (en) * 1983-01-13 1986-03-04 The Board Of Trustees Of The Leland Stanford Jr. University Methods and cell lines for immortalization and monoclonal antibody production by antigen-stimulated B-lymphocytes
FR2543570B1 (fr) * 1983-03-31 1985-08-09 Pasteur Institut Anticorps monoclonaux anticytomegalovirus humains, hybridomes secreteurs de ces anticorps et polypeptides porteurs d'un determinant antigenique sequentiel de cytomegalovirus humains
GB8404368D0 (en) * 1984-02-20 1984-03-28 Cogent Ltd Monoclonal antibodies to human cytomegalovirus
DE3581400D1 (de) * 1984-09-28 1991-02-21 Teijin Ltd Maus/mensch-hybridoma mit erzeugung von antiviralen menschlichen antikoerpern, deren herstellung und antivirale menschliche monoklonale antikoerper.
JP2933786B2 (ja) * 1992-10-13 1999-08-16 甲南電機株式会社 逃がし弁
JPH06181782A (ja) * 1992-12-21 1994-07-05 Mitsubishi Petrochem Co Ltd 酵素反応方法

Also Published As

Publication number Publication date
DE3650032D1 (de) 1994-09-22
KR880700823A (ko) 1988-04-12
WO1987003602A1 (en) 1987-06-18
US5043281A (en) 1991-08-27
KR910000736B1 (ko) 1991-02-06
AU590656B2 (en) 1989-11-09
EP0248909B1 (de) 1994-08-17
EP0248909A4 (de) 1989-11-07
AU6721887A (en) 1987-06-30
ATE110084T1 (de) 1994-09-15
EP0248909A1 (de) 1987-12-16

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