DE3586335D1 - Herstellung von gamma-interferon. - Google Patents

Herstellung von gamma-interferon.

Info

Publication number
DE3586335D1
DE3586335D1 DE8585105058T DE3586335T DE3586335D1 DE 3586335 D1 DE3586335 D1 DE 3586335D1 DE 8585105058 T DE8585105058 T DE 8585105058T DE 3586335 T DE3586335 T DE 3586335T DE 3586335 D1 DE3586335 D1 DE 3586335D1
Authority
DE
Germany
Prior art keywords
production
gamma interferon
interferon
gamma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585105058T
Other languages
English (en)
Other versions
DE3586335T2 (de
Inventor
Michel Revel
Menachem Rubinstein
Yves Mory
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Original Assignee
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research and Development Co Ltd filed Critical Yeda Research and Development Co Ltd
Application granted granted Critical
Publication of DE3586335D1 publication Critical patent/DE3586335D1/de
Publication of DE3586335T2 publication Critical patent/DE3586335T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/57—IFN-gamma
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE8585105058T 1984-04-27 1985-04-25 Herstellung von gamma-interferon. Expired - Lifetime DE3586335T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL71691A IL71691A (en) 1984-04-27 1984-04-27 Production of interferon-ypsilon

Publications (2)

Publication Number Publication Date
DE3586335D1 true DE3586335D1 (de) 1992-08-20
DE3586335T2 DE3586335T2 (de) 1993-01-14

Family

ID=11055023

Family Applications (2)

Application Number Title Priority Date Filing Date
DE198585105058T Pending DE159714T1 (de) 1984-04-27 1985-04-25 Herstellung von gamma-interferon.
DE8585105058T Expired - Lifetime DE3586335T2 (de) 1984-04-27 1985-04-25 Herstellung von gamma-interferon.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE198585105058T Pending DE159714T1 (de) 1984-04-27 1985-04-25 Herstellung von gamma-interferon.

Country Status (8)

Country Link
US (1) US4889803A (de)
EP (1) EP0159714B1 (de)
JP (1) JPH0753112B2 (de)
AU (1) AU587576B2 (de)
CA (1) CA1304704C (de)
DE (2) DE159714T1 (de)
IL (1) IL71691A (de)
ZA (1) ZA853138B (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0154186B1 (de) * 1984-02-10 1992-07-22 Cytoclonal Pharmaceutics Inc. Isolierung eines Interferongens und Expression desselben
CA1302320C (en) * 1984-06-11 1992-06-02 Hideo Niwa Expression of human cromosomal interferon-_ in animal cells
DE3545126A1 (de) * 1985-12-19 1987-06-25 Boehringer Mannheim Gmbh Verfahren zur verbesserung der expression von eukaryontenprotein
JP2585532B2 (ja) * 1986-05-10 1997-02-26 三井東圧化学株式会社 動物細胞の形質転換体及びそれを得る方法並びにその形質転換体を用いてｔ−ＰＡを生産する方法
DE3624453A1 (de) * 1986-07-19 1988-01-28 Behringwerke Ag Verfahren zur herstellung von humanem antithrombin iii (atiii), dafuer geeignete vektoren und wirtszellen, so erhaltenes, biologisch aktives atiii und dieses enthaltende arzneimittel
JPS63105675A (ja) * 1986-10-23 1988-05-10 Green Cross Corp:The ヒトウロキナ−ゼの製造方法
JP2694228B2 (ja) * 1987-11-12 1997-12-24 壹夫 柳 抗ｅｂｎａ抗体の測定法
US7037663B2 (en) * 1998-02-19 2006-05-02 Eastern Virginia Medical School Human zona pellucida protein 3 and uses thereof
WO1999042581A1 (en) * 1998-02-19 1999-08-26 Eastern Virginia Medical School RECOMBINANT ACTIVE HUMAN ZONA PELLUCIDA PROTEIN 3 (hZP3)
CA2456821A1 (en) * 2001-08-02 2003-02-13 Trinity Biomedical Technology Corporation Human zona pellucida proteins and methods of their use in diagnosing male infertility
EP2305312B1 (de) 2001-10-10 2015-03-04 ratiopharm GmbH Neumodulierung und Glykokonjugation von Follitropin (FSH)
ES2561985T3 (es) 2001-10-10 2016-03-01 Ratiopharm Gmbh Remodelación y glicoconjugación de anticuerpos
CA2590461A1 (en) 2004-12-23 2006-06-29 Laboratoires Serono S.A. Bcma polypeptides and uses thereof
JP2009516513A (ja) * 2005-11-21 2009-04-23 ラボラトワール セローノ ソシエテ アノニム ハイブリッド抗原結合分子の組成物及び製造方法並びにその使用
CN103044550A (zh) 2006-09-01 2013-04-17 津莫吉尼蒂克斯公司 Il-31单克隆抗体的可变区序列和使用方法
FR2914652B1 (fr) 2007-04-03 2013-01-18 Librophyt Genes codant pour z,z-farnesyl diphosphate synthase et une sesquiterpene synthase a produits multiples et leurs utilisations
EP2724728B1 (de) 2007-06-27 2018-10-17 The United States of America, as Represented by The Secretary, Department of Health and Human Services Komplexe von il-15 und il-15r alpha und verwendungen davon
ES2660036T3 (es) 2007-12-07 2018-03-20 Zymogenetics, Inc. Moléculas de anticuerpo humanizadas específicas para IL-31
US8420088B2 (en) 2008-01-28 2013-04-16 Novartis Ag Methods and compositions using FGF23 fusion polypeptides
TW200936156A (en) 2008-01-28 2009-09-01 Novartis Ag Methods and compositions using Klotho-FGF fusion polypeptides
AU2010282340B2 (en) 2009-08-13 2016-12-22 The Johns Hopkins University Methods of modulating immune function
WO2013027191A1 (en) 2011-08-25 2013-02-28 Novartis Ag Methods and compositions using fgf23 fusion polypeptides
ES2747997T3 (es) 2012-10-24 2020-03-12 Novartis Ag Formas de IL-15R alfa, células que expresan formas de IL-15R alfa, y usos terapéuticos de IL-15R alfa y complejos IL-15/IL-15R alfa
CA2901226C (en) 2013-02-18 2020-11-17 Vegenics Pty Limited Vascular endothelial growth factor binding proteins
EP2843044A1 (de) 2013-09-03 2015-03-04 Roquette Frères Verbesserte Variante von D-Psicose-3-Epimerase und Verwendungen davon
KR102189458B1 (ko) 2013-09-03 2020-12-11 로께뜨프레르 D-사이코스 3-에피머라제의 개선된 변이체 및 그의 용도
EP2853538A1 (de) 2013-09-27 2015-04-01 Université Pierre et Marie Curie (Paris 6) Analoge von Temporin-SHa und Verwendungen davon
EP2876156A1 (de) 2013-11-26 2015-05-27 Commissariat A L'energie Atomique Et Aux Energies Alternatives Neue Enzyme und Verfahren zur Herstellung von hydroxyliertem L-Lysin oder L-Ornithin und Analoga davon
EP2886656A1 (de) 2013-12-18 2015-06-24 Commissariat A L'energie Atomique Et Aux Energies Alternatives Neues Enzym und Verfahren zur Herstellung von 4-hydroxylbenzylalkohol und Derivaten davon
WO2016018920A1 (en) 2014-07-29 2016-02-04 Admune Therapeutics Llc Il-15 and il-15ralpha heterodimer dose escalation regimens for treating conditions
US10010607B2 (en) 2014-09-16 2018-07-03 Institut Curie Method for preparing viral particles with cyclic dinucleotide and use of said particles for inducing immune response
EP3227319B1 (de) 2014-12-04 2019-11-27 Novartis AG Verfahren und zusammensetzungen mit polypeptiden der klotho-variante
CN108368158A (zh) 2015-12-02 2018-08-03 法国农业科学研究院 具有抗微生物活性的新型肽和能够将肽中的l-构型残基转变成d-构型氨基酸的新型酶
SG11201807960PA (en) 2016-03-16 2018-10-30 Inst Curie Method for preparing viral particles with cyclic dinucleotide and use of said particles for treating cancer
EP3246401A1 (de) 2016-05-20 2017-11-22 Commissariat À L'Énergie Atomique Et Aux Énergies Alternatives Neue fettsäuredecarboxylase und deren verwendungen
FR3052462A1 (fr) 2016-06-14 2017-12-15 Dna Script Variants d'une adn polymerase de la famille polx
EP3570870A1 (de) 2017-01-20 2019-11-27 Novartis AG Kombinationstherapie zur behandlung von krebs
CN110177568A (zh) 2017-01-20 2019-08-27 诺华股份有限公司 用于治疗癌症的组合疗法
WO2018229706A1 (en) 2017-06-16 2018-12-20 Novartis Ag Combination therapy for the treatment of cancer
CA3090171A1 (en) 2018-02-02 2019-08-08 Novartis Ag Combination of sting agonist and il-15/il15-ra for the treatment of cancer
EP3838286A1 (de) 2019-12-19 2021-06-23 Latoxan Antimikrobielles peptid aus polistes gallicus gift und dessen analoga
US20210244821A1 (en) 2020-02-05 2021-08-12 Novartis Ag Cho cell expressed het il-15
WO2022223619A1 (en) 2021-04-20 2022-10-27 Institut Curie Compositions and methods for use in immunotherapy
US20240270792A1 (en) 2021-06-11 2024-08-15 Sorbonne Universite Short antimicrobial peptides
WO2023083999A2 (en) 2021-11-10 2023-05-19 Dna Script Novel terminal deoxynucleotidyl transferase (tdt) variants
WO2023083997A2 (en) 2021-11-10 2023-05-19 Dna Script Novel terminal deoxynucleotidyl

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405712A (en) * 1981-07-01 1983-09-20 The United States Of America As Represented By The Department Of Health And Human Services LTR-Vectors
US4656134A (en) * 1982-01-11 1987-04-07 Board Of Trustees Of Leland Stanford Jr. University Gene amplification in eukaryotic cells
ZA831094B (en) * 1982-02-22 1983-11-30 Biogen Nv Dna sequences,recombinant dna molecules and processes for producing human immune interferon-like polypeptides
US4713339A (en) * 1983-01-19 1987-12-15 Genentech, Inc. Polycistronic expression vector construction

Also Published As

Publication number Publication date
EP0159714B1 (de) 1992-07-15
DE159714T1 (de) 1987-09-24
AU4175385A (en) 1985-10-31
EP0159714A2 (de) 1985-10-30
JPH0753112B2 (ja) 1995-06-07
ZA853138B (en) 1985-12-24
IL71691A (en) 1991-04-15
JPS6143990A (ja) 1986-03-03
IL71691A0 (en) 1984-07-31
CA1304704C (en) 1992-07-07
EP0159714A3 (en) 1988-03-30
DE3586335T2 (de) 1993-01-14
US4889803A (en) 1989-12-26
AU587576B2 (en) 1989-08-24

Similar Documents

Publication Publication Date Title
DE3586335D1 (de) Herstellung von gamma-interferon.
FI863378A (fi) Rengoeringsfoerfarande av interferon.
DE3583940D1 (de) Herstellung von streptavidinaehnlichen polypeptiden.
FI871570A0 (fi) Utmatningsanordning foer en fraon en rulle avdragbar materialbana.
DE3579719D1 (de) Herstellung von emulsionen.
DE3689555D1 (de) Herstellung von aliphatischen Polyaminen.
DE3484374D1 (de) Gamma-interferonzusammensetzung.
DE3675680D1 (de) Herstellung von guanidinen.
DE3481568D1 (de) Herstellung von photodioden.
ATE38211T1 (de) Herstellung von zeolith-l.
DK256385D0 (da) Interferonpraeparat
DE3584503D1 (de) Herstellung von emulsionen.
FR2564854B1 (fr) Photobioreacteur.
DE3382074D1 (de) Herstellung von hydroxyarylaldehyden.
DE3685258D1 (de) Verwendung von pflanzenprotoplasten.
DE3752184D1 (de) Herstellung und Verwendungen von gamma-Interferon
DE3381907D1 (de) Herstellung von trifluormethylpyridinen.
DE3582003D1 (de) Herstellung von glycolmonoestern.
DE3581238D1 (de) Mikrobiologische herstellung von l-phenylalanin.
DE3564103D1 (de) Novel alpha-aminoalkyl-alpha-alkylphenylacetonitriles
DE3586574D1 (de) Menschliches gamma-interferon.
DE3579284D1 (de) Herstellung von l-karnitin.
FI852772A0 (fi) Formsten.
DE3670063D1 (de) Herstellung von thioantimonaten.
DK77387A (da) Interleukin

Legal Events

Date Code Title Description
8364 No opposition during term of opposition