DE3581730D1 - Menschlicher tumornekrosisfaktor. - Google Patents

Menschlicher tumornekrosisfaktor.

Info

Publication number
DE3581730D1
DE3581730D1 DE8585905169T DE3581730T DE3581730D1 DE 3581730 D1 DE3581730 D1 DE 3581730D1 DE 8585905169 T DE8585905169 T DE 8585905169T DE 3581730 T DE3581730 T DE 3581730T DE 3581730 D1 DE3581730 D1 DE 3581730D1
Authority
DE
Germany
Prior art keywords
tumorncrosis
factor
human
tumorncrosis factor
human tumorncrosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585905169T
Other languages
English (en)
Inventor
F Mark
M Wang
B Ladner
A Creasey
S Lin
Arsdell N Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/730,696 external-priority patent/US4677064A/en
Priority claimed from US06/760,661 external-priority patent/US4677063A/en
Application filed by Cetus Corp filed Critical Cetus Corp
Application granted granted Critical
Publication of DE3581730D1 publication Critical patent/DE3581730D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE8585905169T 1984-10-15 1985-10-03 Menschlicher tumornekrosisfaktor. Expired - Fee Related DE3581730D1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US66102684A 1984-10-15 1984-10-15
US67036084A 1984-11-09 1984-11-09
US06/730,696 US4677064A (en) 1984-11-09 1985-05-02 Human tumor necrosis factor
US06/760,661 US4677063A (en) 1985-05-02 1985-07-30 Human tumor necrosis factor
PCT/US1985/001921 WO1986002381A1 (en) 1984-10-15 1985-10-03 Human tumor necrosis factor

Publications (1)

Publication Number Publication Date
DE3581730D1 true DE3581730D1 (de) 1991-03-14

Family

ID=27505306

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585905169T Expired - Fee Related DE3581730D1 (de) 1984-10-15 1985-10-03 Menschlicher tumornekrosisfaktor.

Country Status (11)

Country Link
EP (1) EP0200748B1 (de)
JP (1) JPH0866194A (de)
AU (1) AU589919B2 (de)
BG (1) BG60238B1 (de)
DE (1) DE3581730D1 (de)
DK (1) DK279886D0 (de)
ES (1) ES8704547A1 (de)
FI (1) FI862531A0 (de)
IL (1) IL76699A (de)
NO (1) NO174970C (de)
WO (1) WO1986002381A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0155549B1 (de) * 1984-03-06 1991-03-20 Dainippon Pharmaceutical Co., Ltd. DNS den menschlichen Tumornekrosisfaktor kodierend und das menschliche Tumornekronisfaktor-Polypeptid
US5288852A (en) * 1984-03-06 1994-02-22 Dainippon Pharmaceutical Co., Ltd. Human tumor necrosis factor polypeptides
JPS6248634A (ja) * 1985-07-23 1987-03-03 Mochida Pharmaceut Co Ltd 新規アミノ酸組成物、その製造方法及び該アミノ酸組成物を含有する医療組成物
CA1286843C (en) * 1985-10-30 1991-07-23 Leo S. Lin Purification method for proteins
US5425940A (en) * 1986-04-09 1995-06-20 Cetus Oncology Corporation Combination therapy using interleukin-2 and tumor necrosis factor
DE3750056T2 (de) * 1986-06-20 1995-04-06 Dainippon Pharmaceutical Co Polypeptid-Mutanten des menschlichen TNF und für diese Mutanten codierende DNS.
FR2601678B1 (fr) * 1986-07-18 1989-11-24 Inst Nat Sante Rech Med Peptides comprenant la sequence seryl-aspartyl-lysyl-prolyle, procede pour l'extraction du tetrapeptide correspondant, et applications, notamment a la protection de la moelle osseuse au cours de traitements anticancereux par la chimiotherapie
WO1988006625A2 (en) * 1987-02-26 1988-09-07 Cetus Corporation Arginine-depleted human tumor necrosis factor
DE3837012A1 (de) * 1988-01-15 1989-07-27 Knoll Ag Verwendung von tnf und lt zur herstellung von arzneimitteln
JPH0797997B2 (ja) * 1988-04-28 1995-10-25 帝人株式会社 新規生理活性ポリペプチド
DE3841754A1 (de) * 1988-12-12 1990-06-13 Basf Ag Neue tnf-peptide
DE3841764A1 (de) * 1988-12-12 1990-06-13 Basf Ag Neue tnf-peptide
DE3841768A1 (de) * 1988-12-12 1990-06-13 Basf Ag Neue tnf-peptide
DE3843534A1 (de) * 1988-12-23 1990-07-12 Basf Ag Neue tnf-polypeptide
GB8905606D0 (en) * 1989-03-11 1989-04-26 Scras Peptides
DK0491878T3 (da) 1989-08-16 1997-06-23 Chiron Corp Præparater til inhibering af proteinhormondannelse og anvendelser deraf
ATE199398T1 (de) * 1989-10-24 2001-03-15 Chiron Corp Sekretion vom mit gamma-interferon signalpeptid gebundenen humänen protein
EP2953634B1 (de) 2013-02-07 2021-05-26 The General Hospital Corporation Verfahren zur expansion oder abreicherung von t-regulatorischen zellen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL90047A (en) * 1982-10-19 1992-12-01 Cetus Oncology Corp Cysteine-depleted biologically active muteins other than interferon - '
US4518584A (en) 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
EP0148311B1 (de) * 1983-12-26 1988-07-20 Asahi Kasei Kogyo Kabushiki Kaisha Physiologisch aktives Polypeptid
EP0155549B1 (de) * 1984-03-06 1991-03-20 Dainippon Pharmaceutical Co., Ltd. DNS den menschlichen Tumornekrosisfaktor kodierend und das menschliche Tumornekronisfaktor-Polypeptid
US4879226A (en) * 1984-04-06 1989-11-07 Asahi Kasei Kogyo Kabushiki Kaisha Novel human physiologically active polypeptide
DE3517153A1 (de) * 1985-01-07 1986-07-10 Murillo Contreras, Jesús, México Feuerhemmende beschichtungsmischung und verfahren zu deren herstellung
JP2515975B2 (ja) * 1985-02-26 1996-07-10 大日本製薬株式会社 抗腫瘍作用を有するポリペプチド

Also Published As

Publication number Publication date
IL76699A0 (en) 1986-02-28
NO174970C (no) 1994-08-10
ES8704547A1 (es) 1987-04-01
IL76699A (en) 1998-03-10
WO1986002381A1 (en) 1986-04-24
DK279886A (da) 1986-06-13
FI862531A (fi) 1986-06-13
AU5010685A (en) 1986-05-02
NO174970B (no) 1994-05-02
EP0200748A1 (de) 1986-11-12
DK279886D0 (da) 1986-06-13
NO862353D0 (no) 1986-06-12
JPH0866194A (ja) 1996-03-12
EP0200748B1 (de) 1991-02-06
BG60238B2 (bg) 1994-01-18
BG60238B1 (bg) 1994-01-24
ES547871A0 (es) 1987-04-01
NO862353L (no) 1986-06-12
FI862531A0 (fi) 1986-06-13
AU589919B2 (en) 1989-10-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: CHIRON CORP. (N.D.GES.D. STAATES DELAWARE), EMERYV

8339 Ceased/non-payment of the annual fee