DE3571988D1 - Esters of boron analogues of amino acids - Google Patents
Esters of boron analogues of amino acidsInfo
- Publication number
- DE3571988D1 DE3571988D1 DE8585307732T DE3571988T DE3571988D1 DE 3571988 D1 DE3571988 D1 DE 3571988D1 DE 8585307732 T DE8585307732 T DE 8585307732T DE 3571988 T DE3571988 T DE 3571988T DE 3571988 D1 DE3571988 D1 DE 3571988D1
- Authority
- DE
- Germany
- Prior art keywords
- esters
- amino acids
- haloalkyl
- proviso
- benzyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002148 esters Chemical class 0.000 title abstract 2
- 150000001413 amino acids Chemical class 0.000 title 1
- 150000001638 boron Chemical class 0.000 title 1
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol group Chemical group [C@@H]1(CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)[C@H](C)CCCC(C)C HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 125000001188 haloalkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 1
- KKAXNAVSOBXHTE-UHFFFAOYSA-N boranamine Chemical class NB KKAXNAVSOBXHTE-UHFFFAOYSA-N 0.000 abstract 1
- KOXIGEBRUGYXFD-UHFFFAOYSA-N boranylformic acid Chemical compound BC(O)=O KOXIGEBRUGYXFD-UHFFFAOYSA-N 0.000 abstract 1
- FZFAMSAMCHXGEF-UHFFFAOYSA-N chloro formate Chemical compound ClOC=O FZFAMSAMCHXGEF-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005270 trialkylamine group Chemical group 0.000 abstract 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/027—Organoboranes and organoborohydrides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1896—Compounds having one or more Si-O-acyl linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/664,647 US4647555A (en) | 1984-10-25 | 1984-10-25 | Esters of boron analogues of amino acids |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3571988D1 true DE3571988D1 (en) | 1989-09-07 |
Family
ID=24666855
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8585307732T Expired DE3571988D1 (en) | 1984-10-25 | 1985-10-25 | Esters of boron analogues of amino acids |
Country Status (4)
Country | Link |
---|---|
US (1) | US4647555A (de) |
EP (1) | EP0181721B1 (de) |
AT (1) | ATE45162T1 (de) |
DE (1) | DE3571988D1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2610522B1 (fr) * | 1987-02-06 | 1989-08-18 | Gueyne Jean | Produit therapeutique a base de derives organiques du silicium |
US5023513A (en) * | 1989-06-09 | 1991-06-11 | Boron Biologicals, Inc. | Amine-alkylborane derivatives and methods |
US5260427A (en) * | 1991-05-10 | 1993-11-09 | Boron Biolgicals, Inc. | Nucleosidylphosphite-borane compounds and method of making the same |
US5143907A (en) * | 1991-05-10 | 1992-09-01 | Boron Biologicals, Inc. | Phosphite-borane compounds, and method of making and using the same |
GB0111872D0 (en) | 2001-05-15 | 2001-07-04 | Northwick Park Inst For Medica | Therapeutic agents and methods |
US7968605B2 (en) | 2002-02-04 | 2011-06-28 | ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. | Methods for treating inflammatory disease by administering aldehydes and derivatives thereof |
JP2005519928A (ja) | 2002-02-04 | 2005-07-07 | ハース,ベルナー | Co放出能力を有する化合物の投与によって哺乳動物を治療する方法と、co放出能力を有する化合物ならびにその医薬組成物 |
GB0601394D0 (en) | 2006-01-24 | 2006-03-01 | Hemocorm Ltd | Therapeutic delivery of carbon monoxide |
JP5978291B2 (ja) | 2011-04-19 | 2016-08-24 | アルファーマ インコーポレイテッドAlfama,Inc. | 一酸化炭素放出分子およびその使用 |
ES2628634T3 (es) | 2011-07-21 | 2017-08-03 | Alfama, Inc. | Moléculas liberadoras de monóxido de carbono-rutenio y usos de las mismas |
EP2881398A1 (de) | 2013-12-04 | 2015-06-10 | Université de Bordeaux I | Verfahren zur Herstellung von Aminoarylboranverbindungen oder Derivaten davon |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US312989A (en) * | 1885-02-24 | John t | ||
US3018299A (en) * | 1960-07-01 | 1962-01-23 | Union Carbide Corp | Aryl borate addition compounds of amino hydrocarbon silicon compounds |
US3265737A (en) * | 1964-11-03 | 1966-08-09 | Du Pont | Boron amines and process for formation thereof |
US4035409A (en) * | 1974-12-18 | 1977-07-12 | Texaco Inc. | Hydrocarbyl amine substituted propionic ester |
EP0034238B1 (de) * | 1979-12-21 | 1985-04-17 | Duke University | Amin-carboxyborane mit pharmakologischer Wirkung |
US4440941A (en) * | 1980-12-22 | 1984-04-03 | Usv Pharmaceutical Corporation | Aroyl-aminoacids, amides and esters thereof |
-
1984
- 1984-10-25 US US06/664,647 patent/US4647555A/en not_active Expired - Fee Related
-
1985
- 1985-10-25 AT AT85307732T patent/ATE45162T1/de not_active IP Right Cessation
- 1985-10-25 DE DE8585307732T patent/DE3571988D1/de not_active Expired
- 1985-10-25 EP EP85307732A patent/EP0181721B1/de not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0181721B1 (de) | 1989-08-02 |
EP0181721A1 (de) | 1986-05-21 |
US4647555A (en) | 1987-03-03 |
ATE45162T1 (de) | 1989-08-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE3571988D1 (en) | Esters of boron analogues of amino acids | |
IN163624B (de) | ||
ATE15362T1 (de) | Neue dibenzoyl-methan-derivate, verfahren zu ihrer herstellung und ihre verwendung. | |
YU120386A (en) | Process for obtaining 1-substituted oxindole-3-carboxamide | |
DE3853538D1 (de) | Glykosidester und verfahren zur enzymatischen herstellung. | |
ATE28076T1 (de) | Verfahren zur herstellung von tetrahydropyridinen. | |
GR3001523T3 (en) | Substituted pyrimidine amides of oleic or linoleic acid as inhibitors of acyl-coa cholesterol acyltransferase | |
NO895002D0 (no) | Enzymhemmende aminosyrederivater. | |
DK182783D0 (da) | Fremgangsmade til fremstilling af 1-carboxy-(alkanoyl eller aralkanoyl)-indolin-2-carboxylsyreestere eller salte deraf | |
DE3464619D1 (en) | Pentaerythritol-spiro-bis-phosphite compositions having improved hydrolytic stability | |
RO103073B1 (en) | Installation for additive injection in smelting mass | |
DK444982A (da) | Substituerede hydroxymalonsyrediamider, fremgangsmaade til fremstilling deraf samt deres anvendelse som skadedyrsbekaempende midler | |
DK423188A (da) | Svovlforbindelser, fremgangsmaade til deres fremstilling samt laegemidler indeholdende disse forbindelser | |
ZA873871B (en) | Halogenoolefines | |
DE69501716D1 (de) | Verfahren zur Herstellung von Halogendifluoressigsäurealkylester | |
ATE175419T1 (de) | Verfahren zur herstellung von 4-amino-delta 4-3- ketosteroiden via 4-nitro-delta-4-3-ketosteroiden | |
ES538959A0 (es) | Procedimiento para fotoestabilizar molsidomina | |
DK451282A (da) | Fremgangsmaade til fremstilling af thiazolidinylestere af mineralsyrer | |
ATE31769T1 (de) | Wandverkleidung. | |
ATE105293T1 (de) | Phosphortrilactame und verfahren zu deren herstellung. | |
DE19675016I2 (de) | Verfahren zur Herstellung von 17-Alpha-acyloxy-6-chlor-1-alpha, 2-alpha-methylen-4,6-pregnadien-3, 20-dionen. | |
ATE12770T1 (de) | Ester von 7-hydroxylalkyl-1,3-dimethylxanthinen, verfahren zu ihrer herstellung und ihre verwendung als lipidsenkende mittel. | |
ATE16696T1 (de) | Verfahren zur herstellung von 3-alkyl-6-methylbeta-resorcylsaeureestern. | |
AU4771090A (en) | Methyl-3,3-dialkoxy-1-propylphosphinic acid esters, the corresponding 3-oxo compounds, and a process for their preparation | |
KR930002339A (ko) | 모충 박멸제의 헤테로 시클릭 화합물 및 그의 제조방법 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |