ATE45162T1 - Ester von boranaloga von aminosaeuren. - Google Patents

Ester von boranaloga von aminosaeuren.

Info

Publication number: ATE45162T1
Authority: AT; Austria
Prior art keywords: esters; boranalogues; amino acids; haloalkyl; proviso
Prior art date: 1984-10-25

Application number

AT85307732T

Other languages

English (en)

Inventor

Bernard F Spielvogel

Andrew T Mcphail

Iris H Hall

Original Assignee

Univ Duke

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-25

Filing date

1985-10-25

Publication date

1989-08-15

1985-10-25 Application filed by Univ Duke filed Critical Univ Duke

1989-08-15 Application granted granted Critical

1989-08-15 Publication of ATE45162T1 publication Critical patent/ATE45162T1/de

Links

150000001413 amino acids Chemical class 0.000 title 1
125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 2
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol group Chemical group [C@@H]1(CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)[C@H](C)CCCC(C)C HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
125000001188 haloalkyl group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
150000001412 amines Chemical class 0.000 abstract 1
KKAXNAVSOBXHTE-UHFFFAOYSA-N boranamine Chemical class NB KKAXNAVSOBXHTE-UHFFFAOYSA-N 0.000 abstract 1
KOXIGEBRUGYXFD-UHFFFAOYSA-N boranylformic acid Chemical compound BC(O)=O KOXIGEBRUGYXFD-UHFFFAOYSA-N 0.000 abstract 1
FZFAMSAMCHXGEF-UHFFFAOYSA-N chloro formate Chemical compound ClOC=O FZFAMSAMCHXGEF-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
125000005270 trialkylamine group Chemical group 0.000 abstract 1
UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/027—Organoboranes and organoborohydrides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1896—Compounds having one or more Si-O-acyl linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT85307732T 1984-10-25 1985-10-25 Ester von boranaloga von aminosaeuren. ATE45162T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/664,647 US4647555A (en)	1984-10-25	1984-10-25	Esters of boron analogues of amino acids
EP85307732A EP0181721B1 (de)	1984-10-25	1985-10-25	Ester von Boranaloga von Aminosäuren

Publications (1)

Publication Number	Publication Date
ATE45162T1 true ATE45162T1 (de)	1989-08-15

Family

ID=24666855

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT85307732T ATE45162T1 (de)	1984-10-25	1985-10-25	Ester von boranaloga von aminosaeuren.

Country Status (4)

Country	Link
US (1)	US4647555A (de)
EP (1)	EP0181721B1 (de)
AT (1)	ATE45162T1 (de)
DE (1)	DE3571988D1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2610522B1 (fr) *	1987-02-06	1989-08-18	Gueyne Jean	Produit therapeutique a base de derives organiques du silicium
US5023513A (en) *	1989-06-09	1991-06-11	Boron Biologicals, Inc.	Amine-alkylborane derivatives and methods
US5260427A (en) *	1991-05-10	1993-11-09	Boron Biolgicals, Inc.	Nucleosidylphosphite-borane compounds and method of making the same
US5143907A (en) *	1991-05-10	1992-09-01	Boron Biologicals, Inc.	Phosphite-borane compounds, and method of making and using the same
GB0111872D0 (en)	2001-05-15	2001-07-04	Northwick Park Inst For Medica	Therapeutic agents and methods
US7968605B2 (en)	2002-02-04	2011-06-28	ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda.	Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
JP2005519928A (ja)	2002-02-04	2005-07-07	ハース，ベルナー	Ｃｏ放出能力を有する化合物の投与によって哺乳動物を治療する方法と、ｃｏ放出能力を有する化合物ならびにその医薬組成物
GB0601394D0 (en)	2006-01-24	2006-03-01	Hemocorm Ltd	Therapeutic delivery of carbon monoxide
JP5978291B2 (ja)	2011-04-19	2016-08-24	アルファーマインコーポレイテッドＡｌｆａｍａ，Ｉｎｃ．	一酸化炭素放出分子およびその使用
ES2628634T3 (es)	2011-07-21	2017-08-03	Alfama, Inc.	Moléculas liberadoras de monóxido de carbono-rutenio y usos de las mismas
EP2881398A1 (de)	2013-12-04	2015-06-10	Université de Bordeaux I	Verfahren zur Herstellung von Aminoarylboranverbindungen oder Derivaten davon

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US312989A (en) *		1885-02-24		John t
US3018299A (en) *	1960-07-01	1962-01-23	Union Carbide Corp	Aryl borate addition compounds of amino hydrocarbon silicon compounds
US3265737A (en) *	1964-11-03	1966-08-09	Du Pont	Boron amines and process for formation thereof
US4035409A (en) *	1974-12-18	1977-07-12	Texaco Inc.	Hydrocarbyl amine substituted propionic ester
EP0034238B1 (de) *	1979-12-21	1985-04-17	Duke University	Amin-carboxyborane mit pharmakologischer Wirkung
US4440941A (en) *	1980-12-22	1984-04-03	Usv Pharmaceutical Corporation	Aroyl-aminoacids, amides and esters thereof

1984
- 1984-10-25 US US06/664,647 patent/US4647555A/en not_active Expired - Fee Related
1985
- 1985-10-25 AT AT85307732T patent/ATE45162T1/de not_active IP Right Cessation
- 1985-10-25 DE DE8585307732T patent/DE3571988D1/de not_active Expired
- 1985-10-25 EP EP85307732A patent/EP0181721B1/de not_active Expired

Also Published As

Publication number	Publication date
EP0181721B1 (de)	1989-08-02
EP0181721A1 (de)	1986-05-21
DE3571988D1 (en)	1989-09-07
US4647555A (en)	1987-03-03

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Legal Events

Date	Code	Title	Description
1990-01-15	UEP	Publication of translation of european patent specification
1996-07-15	REN	Ceased due to non-payment of the annual fee