DE3486441D1 - 3-Hydroxypyrid-4-one und pharmazeutische Zusammensetzungen - Google Patents
3-Hydroxypyrid-4-one und pharmazeutische ZusammensetzungenInfo
- Publication number
- DE3486441D1 DE3486441D1 DE3486441T DE3486441T DE3486441D1 DE 3486441 D1 DE3486441 D1 DE 3486441D1 DE 3486441 T DE3486441 T DE 3486441T DE 3486441 T DE3486441 T DE 3486441T DE 3486441 D1 DE3486441 D1 DE 3486441D1
- Authority
- DE
- Germany
- Prior art keywords
- hydroxypyrid
- pharmaceutical compositions
- pharmaceutical
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB838308054A GB8308054D0 (en) | 1983-03-24 | 1983-03-24 | Pharmaceutical compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3486441D1 true DE3486441D1 (de) | 1996-12-19 |
DE3486441T2 DE3486441T2 (de) | 1997-05-07 |
Family
ID=10540098
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8484301881T Expired - Lifetime DE3483973D1 (de) | 1983-03-24 | 1984-03-20 | Hydroxypyridone und ihre pharmazeutischen zusammensetzungen. |
DE3486441T Expired - Lifetime DE3486441T2 (de) | 1983-03-24 | 1984-03-20 | 3-Hydroxypyrid-4-one und pharmazeutische Zusammensetzungen |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8484301881T Expired - Lifetime DE3483973D1 (de) | 1983-03-24 | 1984-03-20 | Hydroxypyridone und ihre pharmazeutischen zusammensetzungen. |
Country Status (9)
Country | Link |
---|---|
US (2) | US4585780A (de) |
EP (1) | EP0120669B1 (de) |
JP (2) | JPH0672097B2 (de) |
CY (1) | CY1510A (de) |
DE (2) | DE3483973D1 (de) |
GB (2) | GB8308054D0 (de) |
GR (1) | GR81911B (de) |
HK (1) | HK37590A (de) |
SG (1) | SG71089G (de) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4912118A (en) * | 1983-09-23 | 1990-03-27 | National Research Development Corporation | Pharmaceutical compositions |
GB8329043D0 (en) * | 1983-10-31 | 1983-11-30 | Hider R C | Pharmaceutical compositions |
US5177068A (en) * | 1984-04-19 | 1993-01-05 | National Research Development Corporation | Pharmaceutical compositions |
US5089644A (en) * | 1985-01-04 | 1992-02-18 | Salutar Inc. | Preparation of oxamine complexes |
US4908371A (en) * | 1987-11-10 | 1990-03-13 | Ciba-Geigy Corporation | Esterified hydroxy dihydropyridinones for treating diseases associated with trivalent metal ion overload |
WO1989009211A1 (en) * | 1988-03-31 | 1989-10-05 | The Royal Free Hospital School Of Medicine | Process for producing pyrid-4-ones |
GB8910521D0 (en) * | 1989-05-08 | 1989-06-21 | Nat Res Dev | The stabilization of organic compounds |
GB9002061D0 (en) * | 1990-01-30 | 1990-03-28 | Bannister Joseph V | Iron assay |
GB9100465D0 (en) * | 1991-01-09 | 1991-02-20 | Hider Robert C | Pharmaceutical compositions |
US5403862A (en) * | 1992-01-17 | 1995-04-04 | University Of Utah Research Foundation | Method for oral decorporation of metals |
US5494935A (en) * | 1992-01-17 | 1996-02-27 | University Of Utah Research Foundation | Methods for oral decorporation of metals |
GB9209078D0 (en) * | 1992-04-27 | 1992-06-10 | Hider Robert C | Pharmaceutical compositions |
GB9217099D0 (en) * | 1992-08-12 | 1992-09-23 | British Tech Group | Pharmaceutical compositions |
US5849587A (en) * | 1995-06-09 | 1998-12-15 | Cornell Research Foundation, Inc. | Method of inhibiting viral replication in eukaryotic cells and of inducing apoptosis of virally-infected cells |
AU6010696A (en) | 1995-06-10 | 1997-01-09 | Vitra Pharmaceuticals Ltd | Iron compounds, compositions, methods of making the same and uses thereof |
JPH0925234A (ja) * | 1995-07-12 | 1997-01-28 | Wakunaga Pharmaceut Co Ltd | 脳疾患改善剤 |
PT768302E (pt) * | 1995-09-29 | 2005-11-30 | Novartis Ag | Novas hidroxipiridinonas |
GB9621273D0 (en) | 1996-10-11 | 1996-11-27 | Cortecs Ltd | Therapeutic method |
GB9625638D0 (en) * | 1996-12-10 | 1997-01-29 | Cenes Ltd | Therapeutic antioxidants for alzheimer's diease |
US5882799A (en) * | 1996-12-16 | 1999-03-16 | Vernay Laboratories, Inc. | Polymeric coupling agents for the adhesion of macromolecular materials and metal substrates |
US6294152B1 (en) * | 1999-01-11 | 2001-09-25 | The University Of Toledo | Iron(III) complexes as contrast agents for image enhancement in magnetic resonance imaging |
US20030024913A1 (en) * | 2002-04-15 | 2003-02-06 | Downes Joseph P. | Laser scanning method and system for marking articles such as printed circuit boards, integrated circuits and the like |
IL135884A (en) * | 2000-04-30 | 2005-08-31 | Yissum Res Dev Co | Method for measuring non-transferrin bound iron |
US7135196B2 (en) * | 2000-09-19 | 2006-11-14 | Vitra Pharmaceuticals Limited | Iron compositions |
US7160482B2 (en) * | 2000-12-22 | 2007-01-09 | Imec Vzw | Composition comprising an oxidizing and complexing compound |
GB0211500D0 (en) * | 2002-05-18 | 2002-06-26 | Vitra Pharmaceuticals Ltd | Method of forming iron hydroxypyrone compounds |
EP1578999B1 (de) | 2002-10-30 | 2013-01-16 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Verfahren zur messung von nichttransferringebundenem eisen |
AU2004285450B2 (en) | 2003-10-20 | 2010-01-14 | Gregory K. Frykman | Zeolite molecular sieves for the removal of toxins |
NZ529657A (en) | 2003-11-20 | 2004-07-30 | Apotex Inc | Iron chelating cycloalkyl derivatives of 3-hydroxy-4-pyridinones |
WO2006028523A2 (en) * | 2004-04-29 | 2006-03-16 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO USDC Technology Transfer Office | Hydroxypyridinone, hydroxypyridinethione, pyrone, and thiopyrone metalloprotein inhibitors |
WO2005110399A2 (en) * | 2004-04-29 | 2005-11-24 | The Regents Of The University Of California | Zinc-binding groups for metalloprotein inhibitors |
UY30986A1 (es) | 2007-03-28 | 2008-09-02 | Apotex Technologies Inc | Derivados fluorinados de deferiprona |
GB0803019D0 (en) * | 2008-02-19 | 2008-03-26 | Btg Int Ltd | Fluorinated compounds |
NZ588602A (en) | 2008-04-25 | 2012-08-31 | Apotex Technologies Inc | Liquid formulation for deferiprone with palatable taste |
DK2448922T3 (da) * | 2009-07-03 | 2014-11-10 | Apotex Technologies Inc | Fluorinerede derivater af 3-hydroxypyridin-4-oner |
GB201007209D0 (en) | 2010-04-29 | 2010-06-16 | King S College London | Compound |
CN102190644B (zh) * | 2011-03-31 | 2012-11-21 | 浙江大学 | 手性3-羟基吡啶-4-酮类衍生物及其合成和用途 |
WO2012137202A1 (en) | 2011-04-05 | 2012-10-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Composition comprising an iron indicator attached to a microparticle and uses of same for quantifying non-transferrin bound iron (ntbi) and cellular labile iron (lci) |
US20180338897A1 (en) * | 2017-05-24 | 2018-11-29 | New York University | Oral compositions for reducing dental stains |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3016372A (en) * | 1956-12-13 | 1962-01-09 | Searle & Co | Glycosides of the pyridone series |
CH449011A (de) * | 1965-04-29 | 1967-12-31 | Geigy Ag J R | Verfahren zur Herstellung von 2,3-Pyridindiol |
AR207322A1 (es) * | 1972-12-18 | 1976-09-30 | Merck & Co Inc | Procedimiento para preparar complejos de 4,4'-dinitrocarbanilidas con derivados de piridonas 2-y 4-substituidas pirimidin-2-y-6-/nas y tetrahidroquinolonas utiles para la prevencion y tratamiento da la coccidiosis |
US3847927A (en) * | 1972-12-20 | 1974-11-12 | Dow Chemical Co | Sulfur-containing hydroxypyridones |
GB1455687A (en) * | 1972-12-28 | 1976-11-17 | Aspro Nicholas Ltd | Pharmacologically active 3-phenyl-3-aminoalkyl-2,6-dioxo-hydro genated pyridines |
JPS5953261B2 (ja) * | 1973-08-03 | 1984-12-24 | 明治製菓株式会社 | 2(1h)−ピリドン誘導体の製造法 |
IE40057B1 (en) * | 1973-11-07 | 1979-02-28 | Richardson Merrell Inc | 4-oxo-1-pyridinyl penicillin and cephalosporin derivatives |
GB1591642A (en) * | 1977-03-03 | 1981-06-24 | Ciba Geigy Ag | Hydroxypyridone dyestuffs |
US4131131A (en) * | 1977-06-22 | 1978-12-26 | Dayco Corporation | Valve construction |
DE3005069A1 (de) * | 1980-02-11 | 1981-08-20 | Cassella Ag, 6000 Frankfurt | Pyridonderivate, ihre herstellung und ihre verwendung |
GB2117766B (en) * | 1982-03-24 | 1985-08-29 | Nat Res Dev | Pharmaceutical compositions |
GB2118176B (en) * | 1982-03-24 | 1985-12-04 | Nat Res Dev | Pharmaceutical compositions |
DK157856C (da) * | 1982-03-24 | 1990-07-30 | Nat Res Dev | Analogifremgangsmaade til fremstilling af et 3:1 hydroxypyridon:jern (iii)-kompleks |
GR78491B (de) * | 1982-03-24 | 1984-09-27 | Nat Res Dev | |
JPS59118792A (ja) * | 1982-12-24 | 1984-07-09 | Kyowa Hakko Kogyo Co Ltd | セフエム化合物 |
US4912118A (en) * | 1983-09-23 | 1990-03-27 | National Research Development Corporation | Pharmaceutical compositions |
GB8325496D0 (en) * | 1983-09-23 | 1983-10-26 | Hider R C | Pharmaceutical compositions |
GB8325494D0 (en) * | 1983-09-23 | 1983-10-26 | Hider R C | Pharmaceutical compositions |
USRE34313E (en) * | 1983-09-23 | 1993-07-13 | National Research Development Corporation | Pharmaceutical compositions |
US5177068A (en) * | 1984-04-19 | 1993-01-05 | National Research Development Corporation | Pharmaceutical compositions |
-
1983
- 1983-03-24 GB GB838308054A patent/GB8308054D0/en active Pending
-
1984
- 1984-03-20 DE DE8484301881T patent/DE3483973D1/de not_active Expired - Lifetime
- 1984-03-20 CY CY1510A patent/CY1510A/xx unknown
- 1984-03-20 DE DE3486441T patent/DE3486441T2/de not_active Expired - Lifetime
- 1984-03-20 EP EP84301881A patent/EP0120669B1/de not_active Expired - Lifetime
- 1984-03-20 GB GB08407181A patent/GB2136807B/en not_active Expired
- 1984-03-22 US US06/592,271 patent/US4585780A/en not_active Ceased
- 1984-03-23 GR GR74187A patent/GR81911B/el unknown
- 1984-03-24 JP JP59057185A patent/JPH0672097B2/ja not_active Expired - Lifetime
-
1989
- 1989-10-25 SG SG710/89A patent/SG71089G/en unknown
-
1990
- 1990-05-17 HK HK375/90A patent/HK37590A/xx not_active IP Right Cessation
-
1993
- 1993-06-22 JP JP5150865A patent/JPH0764815B2/ja not_active Expired - Lifetime
-
1995
- 1995-02-17 US US08/397,321 patent/USRE35948E/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US4585780A (en) | 1986-04-29 |
CY1510A (en) | 1990-08-03 |
GB8308054D0 (en) | 1983-05-05 |
EP0120669A3 (en) | 1985-01-23 |
DE3486441T2 (de) | 1997-05-07 |
JPH0680637A (ja) | 1994-03-22 |
USRE35948E (en) | 1998-11-03 |
EP0120669B1 (de) | 1991-01-23 |
GB2136807A (en) | 1984-09-26 |
SG71089G (en) | 1990-03-02 |
HK37590A (en) | 1990-05-25 |
JPH0672097B2 (ja) | 1994-09-14 |
GB8407181D0 (en) | 1984-04-26 |
DE3483973D1 (de) | 1991-02-28 |
GB2136807B (en) | 1987-04-23 |
GR81911B (de) | 1984-12-12 |
JPS59205361A (ja) | 1984-11-20 |
EP0120669A2 (de) | 1984-10-03 |
JPH0764815B2 (ja) | 1995-07-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: BTG INTERNATIONAL LTD., LONDON, GB |