DE3480653D1 - Pyridazin-derivate, wirksam auf das zentralnervensystem, verfahren zur herstellung, und diese enthaltende arzneimittel. - Google Patents

Pyridazin-derivate, wirksam auf das zentralnervensystem, verfahren zur herstellung, und diese enthaltende arzneimittel.

Info

Publication number
DE3480653D1
DE3480653D1 DE8484400156T DE3480653T DE3480653D1 DE 3480653 D1 DE3480653 D1 DE 3480653D1 DE 8484400156 T DE8484400156 T DE 8484400156T DE 3480653 T DE3480653 T DE 3480653T DE 3480653 D1 DE3480653 D1 DE 3480653D1
Authority
DE
Germany
Prior art keywords
effective
production
ventilation system
products containing
medicinal products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8484400156T
Other languages
English (en)
Inventor
Jean-Pierre Chambon
Kathleen Biziere
Camille-Georges Wermuth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Application granted granted Critical
Publication of DE3480653D1 publication Critical patent/DE3480653D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE8484400156T 1983-01-27 1984-01-25 Pyridazin-derivate, wirksam auf das zentralnervensystem, verfahren zur herstellung, und diese enthaltende arzneimittel. Expired - Fee Related DE3480653D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8301234A FR2540113A1 (fr) 1983-01-27 1983-01-27 Acides derives de la pyridazine actifs sur le systeme nerveux central

Publications (1)

Publication Number Publication Date
DE3480653D1 true DE3480653D1 (de) 1990-01-11

Family

ID=9285330

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484400156T Expired - Fee Related DE3480653D1 (de) 1983-01-27 1984-01-25 Pyridazin-derivate, wirksam auf das zentralnervensystem, verfahren zur herstellung, und diese enthaltende arzneimittel.

Country Status (27)

Country Link
US (1) US4721711A (de)
EP (1) EP0117779B1 (de)
JP (1) JPS59141564A (de)
KR (1) KR910000638B1 (de)
AR (1) AR240045A1 (de)
AT (1) ATE48417T1 (de)
AU (2) AU2372984A (de)
CA (1) CA1238637A (de)
DD (1) DD220026A5 (de)
DE (1) DE3480653D1 (de)
DK (1) DK162985C (de)
ES (1) ES529081A0 (de)
FI (1) FI78691C (de)
FR (1) FR2540113A1 (de)
HU (1) HU193890B (de)
IE (1) IE57054B1 (de)
IL (1) IL70756A (de)
MA (1) MA20018A1 (de)
NO (1) NO840313L (de)
NZ (1) NZ206945A (de)
OA (1) OA07644A (de)
PH (1) PH21162A (de)
PL (1) PL142340B1 (de)
PT (1) PT77993B (de)
SG (1) SG93690G (de)
YU (1) YU14284A (de)
ZA (1) ZA84502B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2540113A1 (fr) * 1983-01-27 1984-08-03 Sanofi Sa Acides derives de la pyridazine actifs sur le systeme nerveux central
DE3664772D1 (en) * 1985-01-14 1989-09-07 Boehringer Ingelheim Kg 12-amino pyridazinoû4',5':3,4¨pyrroloû2,1-a¨isoquinolines, process for their preparation and use
US5082939A (en) * 1987-01-08 1992-01-21 I.S.F. Societa Per Azioni Pyridazine derivatives
US5106973A (en) * 1987-11-23 1992-04-21 Janssen Pharmaceutica N.V. Pyridzainamine derivatives
US5631255A (en) * 1989-02-07 1997-05-20 Sanofi Pyridazine derivatives
FR2663326B2 (fr) * 1989-11-17 1992-10-16 Sanofi Sa Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR2668151A1 (fr) * 1990-10-23 1992-04-24 Rhone Poulenc Agrochimie Composes a groupe triazolopyridazine leurs preparations et compositions herbicides les contenant.
FR2676444B1 (fr) * 1991-05-16 1995-03-10 Sanofi Elf Nouveaux derives d'amino-3 pyridazines actifs sur le systeme nerveux central, procede de preparation et compositions pharmaceutiques en contenant.
CN1038249C (zh) * 1991-08-28 1998-05-06 罗姆和哈斯公司 含有二氢哒嗪酮及其相关化合物的杀菌组合物
US20100210590A1 (en) * 1995-09-27 2010-08-19 Northwestern University Compositions and treatments for seizure-related disorders
US20030176437A1 (en) * 2001-08-31 2003-09-18 D.M. Watterson Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
EP1812007B1 (de) * 2004-11-02 2011-09-07 Northwestern University Pyridazinverbindungen und verfahren
ES2441718T3 (es) 2004-11-02 2014-02-06 Northwestern University Compuestos de piridazina, composiciones y métodos
US20090325973A1 (en) * 2006-04-28 2009-12-31 Watterson D Martin Formulations containing pyridazine compounds
EP2015750A2 (de) * 2006-04-28 2009-01-21 Northwestern University Zusammensetzungen und behandlungen mit pyridazinverbindungen und cholisterinasehemmern
CA2650704A1 (en) * 2006-04-28 2007-11-08 Northwestern University Salts of pyridazine compounds
CN101668732A (zh) * 2007-04-02 2010-03-10 同一世界健康研究院 Cftr抑制剂化合物及其用途
WO2009131958A2 (en) * 2008-04-21 2009-10-29 Institute For Oneworld Health Compounds, compositions and methods comprising triazine derivatives
WO2009131951A2 (en) * 2008-04-21 2009-10-29 Institute For Oneworld Health Compounds, compositions and methods comprising isoxazole derivatives
WO2009131947A2 (en) * 2008-04-21 2009-10-29 Institute For Oneworld Health Compounds, compositions and methods comprising pyridazine derivatives
US8207205B2 (en) 2008-04-21 2012-06-26 Institute For Oneworld Health Compounds, compositions and methods comprising oxadiazole derivatives
JP2012503005A (ja) * 2008-09-19 2012-02-02 インスティテュート フォア ワンワールド ヘルス イミダゾール誘導体およびトリアゾール誘導体を含む、化合物、組成物ならびに方法。
US8343976B2 (en) * 2009-04-20 2013-01-01 Institute For Oneworld Health Compounds, compositions and methods comprising pyrazole derivatives
US20100267706A1 (en) * 2009-04-20 2010-10-21 Institute For Oneworld Health Compounds, Compositions and Methods Comprising Pyridazine Derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2510998B1 (fr) * 1981-08-07 1986-01-10 Sanofi Sa Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent
FR2510997A1 (fr) * 1981-08-10 1983-02-11 Sanofi Sa Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant
FR2540113A1 (fr) * 1983-01-27 1984-08-03 Sanofi Sa Acides derives de la pyridazine actifs sur le systeme nerveux central
CA1218655A (en) * 1983-01-28 1987-03-03 Kathleen Biziere Process for the preparation of pyridazine derivatives having a psychotropic action

Also Published As

Publication number Publication date
SG93690G (en) 1991-01-18
DK162985B (da) 1992-01-06
ES8500243A1 (es) 1984-10-01
KR910000638B1 (ko) 1991-01-31
YU14284A (en) 1986-12-31
PT77993A (fr) 1984-02-01
AU2372984A (en) 1984-08-02
PL245931A1 (en) 1985-07-16
OA07644A (fr) 1985-05-23
IE57054B1 (en) 1992-04-08
FI78691B (fi) 1989-05-31
NZ206945A (en) 1987-07-31
MA20018A1 (fr) 1984-10-01
PL142340B1 (en) 1987-10-31
IL70756A0 (en) 1984-04-30
HU193890B (en) 1987-12-28
KR840007586A (ko) 1984-12-08
AU2142188A (en) 1989-03-16
FI840323A (fi) 1984-07-28
DK38984D0 (da) 1984-01-27
FI840323A0 (fi) 1984-01-26
FR2540113A1 (fr) 1984-08-03
US4721711A (en) 1988-01-26
DK162985C (da) 1992-06-01
FR2540113B1 (de) 1985-05-17
AR240045A1 (es) 1990-01-31
IE840149L (en) 1984-07-27
DK38984A (da) 1984-07-28
ES529081A0 (es) 1984-10-01
PH21162A (en) 1987-08-05
ATE48417T1 (de) 1989-12-15
ZA84502B (en) 1984-09-26
DD220026A5 (de) 1985-03-20
EP0117779B1 (de) 1989-12-06
JPS59141564A (ja) 1984-08-14
AU652118B2 (en) 1994-08-18
NO840313L (no) 1984-07-30
PT77993B (fr) 1986-04-10
FI78691C (fi) 1989-09-11
CA1238637A (en) 1988-06-28
EP0117779A1 (de) 1984-09-05
IL70756A (en) 1987-03-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee