DE3480258D1 - Injectable therapeutic compositions containing stable s-adenosyl-l-methionine salts - Google Patents

Injectable therapeutic compositions containing stable s-adenosyl-l-methionine salts

Info

Publication number
DE3480258D1
DE3480258D1 DE8484109108T DE3480258T DE3480258D1 DE 3480258 D1 DE3480258 D1 DE 3480258D1 DE 8484109108 T DE8484109108 T DE 8484109108T DE 3480258 T DE3480258 T DE 3480258T DE 3480258 D1 DE3480258 D1 DE 3480258D1
Authority
DE
Germany
Prior art keywords
therapeutic compositions
adenosyl
compositions containing
containing stable
injectable therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484109108T
Other languages
English (en)
Inventor
Federico Gennari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioresearch SRL
Original Assignee
Bioresearch SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch SRL filed Critical Bioresearch SRL
Application granted granted Critical
Publication of DE3480258D1 publication Critical patent/DE3480258D1/de
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8484109108T 1983-08-24 1984-08-01 Injectable therapeutic compositions containing stable s-adenosyl-l-methionine salts Expired DE3480258D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22623/83A IT1169774B (it) 1983-08-24 1983-08-24 Composizioni terapeutiche iniettabili contenenti sali stabili della s-adenosil-l-metionina

Publications (1)

Publication Number Publication Date
DE3480258D1 true DE3480258D1 (en) 1989-11-30

Family

ID=11198546

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484109108T Expired DE3480258D1 (en) 1983-08-24 1984-08-01 Injectable therapeutic compositions containing stable s-adenosyl-l-methionine salts

Country Status (8)

Country Link
US (1) US5114931A (de)
EP (1) EP0136463B1 (de)
JP (1) JPS6048925A (de)
AT (1) ATE47518T1 (de)
AU (1) AU564269B2 (de)
CA (1) CA1225032A (de)
DE (1) DE3480258D1 (de)
IT (1) IT1169774B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1229479B (it) * 1989-03-13 1991-09-03 Bioresearch Spa Impiego di 5' deossi 5' metiltioadenosina, di s adenosilmetionina e dei loro sali per la preparazione di composizioni farmaceutiche atte a favorire la crescita dei capelli in soggetti affetti da calvizie e composizioni farmaceutiche relative.
IT1247903B (it) * 1991-02-25 1995-01-05 Bioresearch Spa Impiego della s-adenosil-l-metionina nel trattamento della colestasi intraepatica da nutrizione parenterale totale
ATE173627T1 (de) * 1992-09-04 1998-12-15 Fuji Chem Ind Co Ltd Medizinische zusammensetzung
IT1317920B1 (it) * 2000-10-20 2003-07-15 Univ Roma S-adenosilmetionina e suoi derivati per il trattamento e laprevenzione della malattia di alzheimer.
US6759395B2 (en) 2000-12-18 2004-07-06 Orchid Chemicals & Pharmaceuticals, Ltd. Soft-gelatin capsule comprising S-adenosylmethionine and a method for producing the same
US20050272687A1 (en) * 2004-06-08 2005-12-08 Hebert Rolland F Stable S-adenosyl-l-methionine
US20090012036A1 (en) * 2005-05-24 2009-01-08 Hebert Rolland F Stable S-adenosyl-L-methionine
ES2824807T3 (es) 2013-01-16 2021-05-13 Hebert Sam E Llc Sales de indol-3-propionato estables de S-adenosil-L-metionina
IT201900015192A1 (it) * 2019-08-29 2021-03-01 Graal S R L Formulazioni edibili a base di principi attivi e arginina

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE37913B1 (en) * 1972-08-02 1977-11-09 Bioresearch Sas Salt of s-adenosyl-l-methionine
AR221676A1 (es) * 1974-07-12 1981-03-13 Bioresearch Sas Procedimiento para la preparacion de sales estables sulfonicas y/o sulfuricas de la s-adenosil-l-metionina,particularmente utiles como donadores especificos de metilo para las reacciones bioquimicas de transferencia del grupo ch3;asi como tambien las reacciones fundamentales en el metabolismo lipilico,protilico y glucidico
JPS5195120A (en) * 1975-02-10 1976-08-20 Tenganekino seizoho
JPS6021570B2 (ja) * 1978-07-04 1985-05-28 三共株式会社 ド−パ類の高濃度製剤の製法
IT1137892B (it) * 1981-08-24 1986-09-10 Bioresearch Srl Sali stabili della s-adenosilmetionina,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo
JPS5841898A (ja) * 1981-09-07 1983-03-11 Yamasa Shoyu Co Ltd S−アデノシル−l−ホモシステインの製造法

Also Published As

Publication number Publication date
IT1169774B (it) 1987-06-03
CA1225032A (en) 1987-08-04
ATE47518T1 (de) 1989-11-15
EP0136463A3 (en) 1985-06-12
AU3232784A (en) 1985-02-28
EP0136463A2 (de) 1985-04-10
US5114931A (en) 1992-05-19
IT8322623A1 (it) 1985-02-24
JPS6048925A (ja) 1985-03-16
AU564269B2 (en) 1987-08-06
EP0136463B1 (de) 1989-10-25
IT8322623A0 (it) 1983-08-24
JPH027575B2 (de) 1990-02-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BIORESEARCH S.P.A., LISCATE, MAILAND/MILANO, IT

8328 Change in the person/name/address of the agent

Free format text: HOFFMANN, EITLE & PARTNER PATENT- UND RECHTSANWAELTE, 81925 MUENCHEN

8339 Ceased/non-payment of the annual fee