DE3168572D1 - Cephalosporin derivatives, process for their preparation and antibiotic compositions containing them - Google Patents

Cephalosporin derivatives, process for their preparation and antibiotic compositions containing them

Info

Publication number
DE3168572D1
DE3168572D1 DE8181400430T DE3168572T DE3168572D1 DE 3168572 D1 DE3168572 D1 DE 3168572D1 DE 8181400430 T DE8181400430 T DE 8181400430T DE 3168572 T DE3168572 T DE 3168572T DE 3168572 D1 DE3168572 D1 DE 3168572D1
Authority
DE
Germany
Prior art keywords
preparation
compositions containing
cephalosporin derivatives
antibiotic compositions
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181400430T
Other languages
English (en)
Inventor
Bernard Labeeuw
Ali Salhi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9240143&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3168572(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi SA filed Critical Sanofi SA
Application granted granted Critical
Publication of DE3168572D1 publication Critical patent/DE3168572D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Thermal Transfer Or Thermal Recording In General (AREA)
DE8181400430T 1980-03-26 1981-03-20 Cephalosporin derivatives, process for their preparation and antibiotic compositions containing them Expired DE3168572D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8006757A FR2479229B1 (fr) 1980-03-26 1980-03-26 Nouveaux derives des cephalosporines, leur procede de preparation et les medicaments utilisables comme antibiotiques qui contiennent lesdits derives

Publications (1)

Publication Number Publication Date
DE3168572D1 true DE3168572D1 (en) 1985-03-14

Family

ID=9240143

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181400430T Expired DE3168572D1 (en) 1980-03-26 1981-03-20 Cephalosporin derivatives, process for their preparation and antibiotic compositions containing them

Country Status (9)

Country Link
US (1) US4464367A (de)
EP (1) EP0036812B1 (de)
JP (1) JPS57154191A (de)
AT (1) ATE11541T1 (de)
CA (1) CA1140114A (de)
DE (1) DE3168572D1 (de)
FR (1) FR2479229B1 (de)
LU (1) LU88361I2 (de)
NL (1) NL930130I1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60120886A (ja) * 1983-12-02 1985-06-28 Takeda Chem Ind Ltd セフェムカルボン酸のナトリウム塩の結晶
FR2570702B1 (fr) * 1984-09-27 1987-01-09 Sanofi Sa Derives des cephalosporines, procedes d'obtention et leur application a titre d'antibiotiques
IT1181672B (it) * 1984-10-25 1987-09-30 Upjohn Co Cefalosporina alogenidrato cristallino
US4902683A (en) * 1984-10-25 1990-02-20 The Upjohn Company Crystalline cephalosporin hydrohalide salts
WO1987001117A2 (en) * 1985-08-12 1987-02-26 The Upjohn Company Conversion of cephalosporin hydrohalide salt to alkali metal salt
EP0263901A1 (de) * 1986-10-08 1988-04-20 The Upjohn Company Umsetzung von Cephalosporinhalogenwasserstoffsäuresalz in Alkalimetallsalz
US5147871A (en) * 1986-07-03 1992-09-15 Hoffmann La-Roche, Inc. Anti-bacterial cephalosporin compounds
US5189157A (en) * 1987-06-16 1993-02-23 Hoffmann La Roche Inc. Antibacterial cephalosporin compounds
DE3869135D1 (de) * 1987-07-29 1992-04-16 Upjohn Co Kontrollierte freisetzung von antibiotika-salzen aus einem implantat.
US5223496A (en) * 1987-11-10 1993-06-29 The Upjohn Company Cephalosporin antibiotics
KR0128242B1 (ko) * 1987-11-10 1998-04-02 로버트 에이. 아미테이지 세팔로스포린 항생물질
NZ227470A (en) * 1987-12-28 1991-06-25 Hoffmann La Roche Acyl derivatives of substituted cephem compounds; pharmaceutical compositions and methods for preparation and treatment
AU612468B2 (en) * 1988-02-16 1991-07-11 Upjohn Company, The Zinc ceftiofur complexes
US4877782A (en) * 1988-02-16 1989-10-31 The Upjohn Company Zinc ceftiofur complexes
US5162523A (en) * 1989-07-21 1992-11-10 Hoffmann-La Roche Inc. Cephalosporin antibacterial compounds
US5159077A (en) * 1989-07-21 1992-10-27 Hoffmann-La Roche Inc. Penam antibacterial compounds
AU694419B2 (en) * 1993-03-12 1998-07-23 Zoetis P&U Llc Crystalline ceftiofur free acid
US5929086A (en) * 1996-05-10 1999-07-27 Pharmacia & Upjohn Company Topical administration of antimicrobial agents for the treatment of systemic bacterial diseases
US5736151A (en) * 1996-12-09 1998-04-07 Pharmacia & Upjohn Company Antibiotic oil suspensions
US6074657A (en) * 1997-03-20 2000-06-13 Pharmacia & Upjohn Company Administration of an injectable antibiotic in the ear of an animal
US6458949B1 (en) * 2000-08-14 2002-10-01 Aurobindo Pharma Limited Ceftiofur, its intermediate and a process for the preparation of the same
KR100502390B1 (ko) * 2001-09-07 2005-07-19 주식회사 엘지생명과학 세팔로스포린산 유도체의 제조방법
US6555679B2 (en) 2001-10-03 2003-04-29 Orchid Chemicals & Pharmaceuticals Ltd. Method for preparation of ceftiofur sodium from its hydrohalide salts
US6555680B1 (en) 2001-12-10 2003-04-29 Orchid Chemicals & Pharmaceuticals Ltd. Method for the preparation of ceftiofur sodium
AU2002222353A1 (en) * 2001-12-11 2003-06-23 Orchid Chemicals And Pharmaceuticals Limited A new method for the preparation of ceftiofur sodium
US20030135041A1 (en) 2002-01-04 2003-07-17 Orchid Chemicals & Pharmaceuticals Limited, India Synthesis of ceftiofur intermediate
AU2002219436A1 (en) * 2002-01-15 2003-07-30 Orchid Chemicals And Pharmaceuticals Limited An improved synthesis of ceftiofur intermediate
US6800756B2 (en) * 2002-05-03 2004-10-05 Orchid Chemicals And Pharmaceuticals, Ltd. Method for the preparation of ceftiofur sodium and its intermediates
US7335767B2 (en) * 2002-10-29 2008-02-26 Lupin Limited Method for preparation of ceftiofur and salts thereof
US7842791B2 (en) * 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
US20060094872A1 (en) * 2003-08-22 2006-05-04 Orchid Chemicals & Pharmaceuticals Ltd. Process for the preparation of cephalosporin antibiotic
WO2005019227A1 (en) * 2003-08-22 2005-03-03 Orchid Chemicals & Pharmaceuticals Ltd Process for the preparation of cephalosporin antibiotic
US8470809B2 (en) * 2005-10-12 2013-06-25 Orchid Chemicals & Pharmaceuticals Limited Crystalline sodium salt of cephalosporin antibiotic
EP2324034A4 (de) * 2008-08-22 2012-05-16 Orchid Chemicals & Pharm Ltd Kristallines natriumsalz eines cephalosporin-antibiotikums
CN104610281B (zh) * 2015-02-09 2016-01-13 施维雅(青岛)生物制药有限公司 头孢噻呋镁及其制备和使用方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2342733A1 (fr) * 1976-01-14 1977-09-30 Roussel Uclaf Derives de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4202893A (en) * 1976-03-25 1980-05-13 Roussel Uclaf Alkyloximes of 7-amino-thiazolyl-acetamido-cephalosporanic acids
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
JPS57154191A (en) 1982-09-22
NL930130I1 (nl) 1993-11-01
CA1140114A (en) 1983-01-25
FR2479229A1 (fr) 1981-10-02
EP0036812B1 (de) 1985-01-30
LU88361I2 (fr) 1994-05-04
ATE11541T1 (de) 1985-02-15
US4464367A (en) 1984-08-07
FR2479229B1 (fr) 1986-01-17
EP0036812A1 (de) 1981-09-30
JPH0255437B2 (de) 1990-11-27

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Legal Events

Date Code Title Description
V448 Application of spc

Free format text: PRODUCT NAME: CEFTIOFUR-NATRIUM; REGISTRATION NO/DATE: 34100.00.00, 34100.01.00; 19950215

Spc suppl protection certif: 195 75 028

Filing date: 19950804

8327 Change in the person/name/address of the patent owner

Owner name: THE UPJOHN CO., KALAMAZOO, MICH., US

8328 Change in the person/name/address of the agent

Free format text: FEILER UND KOLLEGEN, 81675 MUENCHEN

8327 Change in the person/name/address of the patent owner

Owner name: PHARMACIA & UPJOHN CO., KALAMAZOO, MICH., US

V457 Spc granted

Free format text: PRODUCT NAME: CEFTIOFUR-NATRIUM; REGISTRATION NO/DATE: 34100.00.00, 34100.01.00; 19950215

Spc suppl protection certif: 195 75 028

Filing date: 19950804

V464 Spc expired

Free format text: PRODUCT NAME: CEFTIOFUR-NATRIUM; REGISTRATION NO/DATE: 34100.00.00, 34100.01.00; 19950215

Spc suppl protection certif: 195 75 028

Filing date: 19950804