DE2967642D1 - Azabicyclo alkyl derivatives - Google Patents

Azabicyclo alkyl derivatives

Info

Publication number
DE2967642D1
DE2967642D1 DE8282109116T DE2967642T DE2967642D1 DE 2967642 D1 DE2967642 D1 DE 2967642D1 DE 8282109116 T DE8282109116 T DE 8282109116T DE 2967642 T DE2967642 T DE 2967642T DE 2967642 D1 DE2967642 D1 DE 2967642D1
Authority
DE
Germany
Prior art keywords
alkyl derivatives
azabicyclo
azabicyclo alkyl
derivatives
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282109116T
Other languages
English (en)
Inventor
Michael Stewart Hadley
Francis David King
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Application granted granted Critical
Publication of DE2967642D1 publication Critical patent/DE2967642D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE8282109116T 1978-12-30 1979-12-20 Azabicyclo alkyl derivatives Expired DE2967642D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB7850380 1978-12-30
GB7909262 1979-03-15
GB7927831 1979-08-09
EP79302978A EP0013138B1 (de) 1978-12-30 1979-12-20 Azabicycloalkyl-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
DE2967642D1 true DE2967642D1 (de) 1987-01-29

Family

ID=27260652

Family Applications (3)

Application Number Title Priority Date Filing Date
DE8585115575T Expired DE2967692D1 (de) 1978-12-30 1979-12-20 Azabicycloalkyl derivatives
DE7979302978T Expired DE2966476D1 (en) 1978-12-30 1979-12-20 Azabicycloalkyl derivatives, a process for their preparation and pharmaceutical compositions containing them
DE8282109116T Expired DE2967642D1 (de) 1978-12-30 1979-12-20 Azabicyclo alkyl derivatives

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE8585115575T Expired DE2967692D1 (de) 1978-12-30 1979-12-20 Azabicycloalkyl derivatives
DE7979302978T Expired DE2966476D1 (en) 1978-12-30 1979-12-20 Azabicycloalkyl derivatives, a process for their preparation and pharmaceutical compositions containing them

Country Status (14)

Country Link
US (5) US4273778A (de)
EP (3) EP0081054B1 (de)
AR (1) AR225301A1 (de)
AT (1) ATE24320T1 (de)
AU (2) AU527837B2 (de)
CA (2) CA1218062A (de)
DE (3) DE2967692D1 (de)
DK (1) DK553979A (de)
ES (1) ES8101072A1 (de)
IE (2) IE49737B1 (de)
IL (1) IL59004A0 (de)
MX (1) MX6255E (de)
NZ (1) NZ192476A (de)
ZA (1) ZA797054B (de)

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DE3368061D1 (en) * 1982-05-11 1987-01-15 Beecham Group Plc Azabicycloalkane derivatives, their preparation and medicaments containing them
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EP0099194A3 (de) * 1982-07-03 1984-04-11 Beecham Group Plc Benzamide
JPS5936675A (ja) * 1982-07-13 1984-02-28 サンド・アクチエンゲゼルシヤフト 二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド
EP0101641A3 (de) * 1982-07-22 1984-03-28 Beecham Group Plc Sulphonylamino-aza-bicycloalkyl-Derivate
EP0102195A3 (de) * 1982-08-03 1984-04-11 Beecham Group Plc Substituierte Azabicycloalkyl-Derivate mit dopaminantagonistischer Wirkung
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GB8516371D0 (en) * 1985-06-28 1985-07-31 Beecham Group Plc Compounds
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DK2268646T3 (da) 2008-04-11 2013-11-18 Janssen Pharmaceutica Nv Thiazolopyridin-2-yloxy-phenyl og thiazolopyrazin-2-yloxy-phenyl-aminer som modulatorer af leukotrien-a4-hydrolase
CN102459251B (zh) * 2009-05-14 2015-05-20 詹森药业有限公司 作为白三烯a4水解酶的调节剂的具有两个稠合双环杂芳基部分的化合物
CN104860946A (zh) * 2015-05-14 2015-08-26 湖北生物医药产业技术研究院有限公司 Ccr5拮抗剂的制备方法
JP2021512952A (ja) * 2018-02-05 2021-05-20 アルカームス・インコーポレイテッド 疼痛の処置のための化合物

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Also Published As

Publication number Publication date
IL59004A0 (en) 1980-03-31
US4544660A (en) 1985-10-01
CA1218062A (en) 1987-02-17
AU527837B2 (en) 1983-03-24
ES487379A0 (es) 1980-12-01
AR225301A1 (es) 1982-03-15
IE792524L (en) 1980-06-30
AU543825B2 (en) 1985-05-02
DK553979A (da) 1980-08-15
AU9135182A (en) 1983-03-10
IE49737B1 (en) 1985-12-11
US4599420A (en) 1986-07-08
US4273778A (en) 1981-06-16
EP0220339B1 (de) 1989-11-08
EP0220339A1 (de) 1987-05-06
US4705858A (en) 1987-11-10
DE2967692D1 (de) 1989-12-14
MX6255E (es) 1985-02-15
ATE24320T1 (de) 1987-01-15
IE49736B1 (en) 1985-12-11
ZA797054B (en) 1980-12-31
EP0081054A2 (de) 1983-06-15
EP0013138B1 (de) 1983-12-07
EP0081054B1 (de) 1986-12-17
ES8101072A1 (es) 1980-12-01
NZ192476A (en) 1982-09-14
US4336259A (en) 1982-06-22
AU5425579A (en) 1980-07-03
EP0081054A3 (en) 1983-08-24
CA1220473A (en) 1987-04-14
DE2966476D1 (en) 1984-01-12
EP0013138A1 (de) 1980-07-09

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