DE2815157A1 - 3-(2-aminoaethylthio)-6-aethyl-7-oxo-1- azabicyclo eckige klammer auf 3.2.0 eckige klammer zu hept-2-en-2-carbonsaeure - Google Patents

3-(2-aminoaethylthio)-6-aethyl-7-oxo-1- azabicyclo eckige klammer auf 3.2.0 eckige klammer zu hept-2-en-2-carbonsaeure

Info

Publication number
DE2815157A1
DE2815157A1 DE19782815157 DE2815157A DE2815157A1 DE 2815157 A1 DE2815157 A1 DE 2815157A1 DE 19782815157 DE19782815157 DE 19782815157 DE 2815157 A DE2815157 A DE 2815157A DE 2815157 A1 DE2815157 A1 DE 2815157A1
Authority
DE
Germany
Prior art keywords
azabicyclo
oxo
hept
solution
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19782815157
Other languages
German (de)
English (en)
Inventor
Ronald William Ratcliffe
Linda Jean Ruswinkle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE2815157A1 publication Critical patent/DE2815157A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE19782815157 1977-04-08 1978-04-07 3-(2-aminoaethylthio)-6-aethyl-7-oxo-1- azabicyclo eckige klammer auf 3.2.0 eckige klammer zu hept-2-en-2-carbonsaeure Ceased DE2815157A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78581177A 1977-04-08 1977-04-08
US86123077A 1977-12-16 1977-12-16

Publications (1)

Publication Number Publication Date
DE2815157A1 true DE2815157A1 (de) 1978-10-19

Family

ID=27120448

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19782815157 Ceased DE2815157A1 (de) 1977-04-08 1978-04-07 3-(2-aminoaethylthio)-6-aethyl-7-oxo-1- azabicyclo eckige klammer auf 3.2.0 eckige klammer zu hept-2-en-2-carbonsaeure

Country Status (11)

Country Link
JP (1) JPS53127491A (fr)
CH (1) CH640236A5 (fr)
DE (1) DE2815157A1 (fr)
DK (1) DK123578A (fr)
FR (1) FR2386545A1 (fr)
GB (1) GB1595267A (fr)
IE (1) IE47043B1 (fr)
IT (1) IT1102456B (fr)
LU (1) LU79403A1 (fr)
NL (1) NL7802826A (fr)
SE (1) SE7803173L (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002058A1 (fr) * 1977-11-17 1979-05-30 Sanraku-Ocean Co., Ltd. 3-(2-Aminoéthylthio-6-éthyl-7-oxo-1-azabicylo-(3.2.0)-hept-2-en-2-acide carboxylique, procédé pour sa préparation et compositions le contenant
EP0005349A1 (fr) * 1978-05-06 1979-11-14 Beecham Group Plc Alkylcarbapénèmes, leur préparation, compositions pharmaceutiques les contenant et les intermédiaires
EP0017246A1 (fr) * 1979-04-06 1980-10-15 Shionogi & Co., Ltd. L'antibiotique PA-31088-IV, ses sels avec des bases, procédé pour sa préparation, compositions pharmaceutiques le contenant, streptomyces tokunonensis PA-31088 et ses mutants
US4235922A (en) * 1979-06-15 1980-11-25 Merck & Co., Inc. 3-(2-Aminoethylthio)-6-ethyl-7-oxo-1-azabicyclo [3.2.0]hept-2-ene-2-carboxylic acid
EP0024832A1 (fr) * 1979-08-10 1981-03-11 Beecham Group Plc Antibiotiques du type bêta-lactame, leur préparation, compositions pharmaceutiques les contenant et leur préparation
EP0030719A1 (fr) * 1979-12-12 1981-06-24 Shionogi & Co., Ltd. Antibiotique PA-39504-X1 et ses sels, procédé pour sa production et compositions pharmaceutiques
EP0049610A1 (fr) * 1980-10-07 1982-04-14 Kowa Company, Ltd. Un composé de carbapénème, ses esters et sels, et procédés pour leur préparation

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR62185B (en) * 1977-03-31 1979-03-02 Panlabs Inc Preparation process of an antibiotic ps-5 and its derivatives with inhibitory activity of b-lactamase
JPS5572191A (en) * 1978-11-22 1980-05-30 Sanraku Inc Antibiotic n-desacetyl ps-5

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002058A1 (fr) * 1977-11-17 1979-05-30 Sanraku-Ocean Co., Ltd. 3-(2-Aminoéthylthio-6-éthyl-7-oxo-1-azabicylo-(3.2.0)-hept-2-en-2-acide carboxylique, procédé pour sa préparation et compositions le contenant
EP0005349A1 (fr) * 1978-05-06 1979-11-14 Beecham Group Plc Alkylcarbapénèmes, leur préparation, compositions pharmaceutiques les contenant et les intermédiaires
EP0017246A1 (fr) * 1979-04-06 1980-10-15 Shionogi & Co., Ltd. L'antibiotique PA-31088-IV, ses sels avec des bases, procédé pour sa préparation, compositions pharmaceutiques le contenant, streptomyces tokunonensis PA-31088 et ses mutants
US4235922A (en) * 1979-06-15 1980-11-25 Merck & Co., Inc. 3-(2-Aminoethylthio)-6-ethyl-7-oxo-1-azabicyclo [3.2.0]hept-2-ene-2-carboxylic acid
EP0024832A1 (fr) * 1979-08-10 1981-03-11 Beecham Group Plc Antibiotiques du type bêta-lactame, leur préparation, compositions pharmaceutiques les contenant et leur préparation
EP0030719A1 (fr) * 1979-12-12 1981-06-24 Shionogi & Co., Ltd. Antibiotique PA-39504-X1 et ses sels, procédé pour sa production et compositions pharmaceutiques
EP0049610A1 (fr) * 1980-10-07 1982-04-14 Kowa Company, Ltd. Un composé de carbapénème, ses esters et sels, et procédés pour leur préparation

Also Published As

Publication number Publication date
NL7802826A (nl) 1978-10-10
LU79403A1 (fr) 1978-11-27
IT1102456B (it) 1985-10-07
IE780631L (en) 1978-10-08
IT7848747A0 (it) 1978-04-05
FR2386545B1 (fr) 1980-08-01
SE7803173L (sv) 1978-10-09
IE47043B1 (en) 1983-12-14
CH640236A5 (en) 1983-12-30
FR2386545A1 (fr) 1978-11-03
DK123578A (da) 1978-10-09
JPS53127491A (en) 1978-11-07
GB1595267A (en) 1981-08-12

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8131 Rejection