DE2640599C2 - - Google Patents
Info
- Publication number
- DE2640599C2 DE2640599C2 DE19762640599 DE2640599A DE2640599C2 DE 2640599 C2 DE2640599 C2 DE 2640599C2 DE 19762640599 DE19762640599 DE 19762640599 DE 2640599 A DE2640599 A DE 2640599A DE 2640599 C2 DE2640599 C2 DE 2640599C2
- Authority
- DE
- Germany
- Prior art keywords
- ammonium
- water
- mixture
- reaction
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19762640599 DE2640599A1 (de) | 1976-09-09 | 1976-09-09 | Verfahren zur herstellung von 1,4- benzodiazepinen |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19762640599 DE2640599A1 (de) | 1976-09-09 | 1976-09-09 | Verfahren zur herstellung von 1,4- benzodiazepinen |
Publications (2)
Publication Number | Publication Date |
---|---|
DE2640599A1 DE2640599A1 (de) | 1978-03-16 |
DE2640599C2 true DE2640599C2 (fr) | 1987-11-05 |
Family
ID=5987537
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19762640599 Granted DE2640599A1 (de) | 1976-09-09 | 1976-09-09 | Verfahren zur herstellung von 1,4- benzodiazepinen |
Country Status (1)
Country | Link |
---|---|
DE (1) | DE2640599A1 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR084070A1 (es) | 2010-12-02 | 2013-04-17 | Constellation Pharmaceuticals Inc | Inhibidores del bromodominio y usos de los mismos |
US9249161B2 (en) | 2010-12-02 | 2016-02-02 | Constellation Pharmaceuticals, Inc. | Bromodomain inhibitors and uses thereof |
US9422292B2 (en) | 2011-05-04 | 2016-08-23 | Constellation Pharmaceuticals, Inc. | Bromodomain inhibitors and uses thereof |
EP2721031B1 (fr) | 2011-06-17 | 2016-01-20 | Constellation Pharmaceuticals, Inc. | Inhibiteurs à bromodomaine et leurs utilisations |
TWI602820B (zh) | 2012-06-06 | 2017-10-21 | 星宿藥物公司 | 溴域抑制劑及其用途 |
EP2864336B1 (fr) | 2012-06-06 | 2016-11-23 | Constellation Pharmaceuticals, Inc. | Inhibiteurs de bromo-domaine de benzo[b]isoxazoloazépines et applications associées |
CA2952830C (fr) | 2014-06-20 | 2022-11-01 | Constellation Pharmaceuticals, Inc. | Formes cristallines de l'acetamide 2-((4s)-6- (4-chlorophenyl)-1-methyl-4 h-benzo [c] isoxazolo [4s5-e] azepin-4-yle) |
-
1976
- 1976-09-09 DE DE19762640599 patent/DE2640599A1/de active Granted
Also Published As
Publication number | Publication date |
---|---|
DE2640599A1 (de) | 1978-03-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8110 | Request for examination paragraph 44 | ||
D2 | Grant after examination | ||
8364 | No opposition during term of opposition |