CY1122872T1 - Ανασυνδυασμενοι hvt φορεις οι οποιοι εκφραζουν αντιγονα παθογονων των πτηνων και χρησεις αυτων - Google Patents
Ανασυνδυασμενοι hvt φορεις οι οποιοι εκφραζουν αντιγονα παθογονων των πτηνων και χρησεις αυτωνInfo
- Publication number
- CY1122872T1 CY1122872T1 CY20191101319T CY191101319T CY1122872T1 CY 1122872 T1 CY1122872 T1 CY 1122872T1 CY 20191101319 T CY20191101319 T CY 20191101319T CY 191101319 T CY191101319 T CY 191101319T CY 1122872 T1 CY1122872 T1 CY 1122872T1
- Authority
- CY
- Cyprus
- Prior art keywords
- recombinant
- vectors
- recombinant hvt
- pathogen antigens
- vectors expressing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- C12N15/869—Herpesviral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/15—Reoviridae, e.g. calf diarrhea virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
- A61K39/17—Newcastle disease virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
- A61K39/255—Marek's disease virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/03—Herpetoviridae, e.g. pseudorabies virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/115—Paramyxoviridae, e.g. parainfluenza virus
- C07K14/125—Newcastle disease virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/14—Reoviridae, e.g. rotavirus, bluetongue virus, Colorado tick fever virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16041—Use of virus, viral particle or viral elements as a vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16041—Use of virus, viral particle or viral elements as a vector
- C12N2710/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16071—Demonstrated in vivo effect
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16341—Use of virus, viral particle or viral elements as a vector
- C12N2710/16343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/00034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/10011—Birnaviridae
- C12N2720/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
- C12N2760/18134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
Η παρούσα εφεύρεση παρέχει ανασυνδυασμένους φορείς ιού του έρπητα από γαλοπούλες (HVT) οι οποίοι περιέχουν και εκφράζουν αντιγόνα παθογόνων των πτηνών, συνθέσεις οι οποίες περιλαμβάνουν τους ανασυνδυασμένους HVT φορείς, πολυσθενή εμβόλια τα οποία περιλαμβάνουν τους ανασυνδυασμένους HVT φορείς και έναν ή περισσότερους αγρίου τύπου ιούς ή ανασυνδυασμένους φορείς. Η παρούσα εφεύρεση περαιτέρω παρέχει μεθόδους εμβολιασμού έναντι μιας ποικιλίας παθογόνων των πτηνών και μέθοδο παραγωγής των ανασυνδυασμένων HVT φορέων.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161564877P | 2011-11-30 | 2011-11-30 | |
US201261694957P | 2012-08-30 | 2012-08-30 | |
PCT/US2012/067135 WO2013082327A1 (en) | 2011-11-30 | 2012-11-29 | Recombinant hvt vectors expressing antigens of avian pathogens and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1122872T1 true CY1122872T1 (el) | 2021-05-05 |
Family
ID=47358292
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20191100394T CY1121528T1 (el) | 2011-11-30 | 2019-04-09 | Ανασυνδυασμενοι φορεις ερπητοϊου gallid 3 (mdv οροτυπου 2) που εκφραζουν αντιγονα παθογονων των πτηνων και χρησεις αυτων |
CY20191101319T CY1122872T1 (el) | 2011-11-30 | 2019-12-16 | Ανασυνδυασμενοι hvt φορεις οι οποιοι εκφραζουν αντιγονα παθογονων των πτηνων και χρησεις αυτων |
CY20201100003T CY1124618T1 (el) | 2011-11-30 | 2020-01-07 | Ανασυνδυασμενοι hvt φορεις οι οποιοι εκφραζουν αντιγονα παθογονων των πτηνων και χρησεις αυτων |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20191100394T CY1121528T1 (el) | 2011-11-30 | 2019-04-09 | Ανασυνδυασμενοι φορεις ερπητοϊου gallid 3 (mdv οροτυπου 2) που εκφραζουν αντιγονα παθογονων των πτηνων και χρησεις αυτων |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20201100003T CY1124618T1 (el) | 2011-11-30 | 2020-01-07 | Ανασυνδυασμενοι hvt φορεις οι οποιοι εκφραζουν αντιγονα παθογονων των πτηνων και χρησεις αυτων |
Country Status (28)
Country | Link |
---|---|
EP (7) | EP3572092A1 (el) |
JP (1) | JP6149301B2 (el) |
KR (1) | KR102013135B1 (el) |
CN (3) | CN104159605B (el) |
AR (2) | AR090401A1 (el) |
BR (1) | BR112014013276B1 (el) |
CA (1) | CA2857025C (el) |
CO (1) | CO7061033A2 (el) |
CY (3) | CY1121528T1 (el) |
DK (3) | DK2785373T3 (el) |
ES (3) | ES2719409T5 (el) |
HK (4) | HK1247832A1 (el) |
HR (3) | HRP20190525T8 (el) |
HU (3) | HUE047909T2 (el) |
IN (1) | IN2014CN04833A (el) |
LT (3) | LT2785373T (el) |
ME (1) | ME03433B (el) |
MX (2) | MX361893B (el) |
PE (1) | PE20141482A1 (el) |
PH (2) | PH12014501174A1 (el) |
PL (3) | PL2785374T5 (el) |
PT (3) | PT2785374T (el) |
RS (3) | RS59892B1 (el) |
RU (1) | RU2620936C2 (el) |
SI (3) | SI2785373T1 (el) |
UA (1) | UA118651C2 (el) |
WO (2) | WO2013082327A1 (el) |
ZA (1) | ZA201403804B (el) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013057236A1 (en) | 2011-10-21 | 2013-04-25 | Intervet International B.V. | Recombinant non-pathogenic marek's disease virus constructs encoding infectious laryngotracheitis virus and newcastle disease virus antigens |
WO2013082327A1 (en) | 2011-11-30 | 2013-06-06 | Merial Limited | Recombinant hvt vectors expressing antigens of avian pathogens and uses thereof |
EP2644702A1 (en) | 2012-03-30 | 2013-10-02 | Ceva Sante Animale | Multivalent recombinant avian herpes virus and vaccine for immunizing avian species |
AR097029A1 (es) * | 2013-07-26 | 2016-02-17 | Intervet Int Bv | Aceleración de la respuesta inmune inducida por virus vectorial en aves, composición, uso, método para la vacunación y método para acelerar la respuesta inmune |
EP2845904A1 (en) * | 2013-09-06 | 2015-03-11 | Ceva Sante Animale | Recombinant Marek's disease viruses and uses thereof |
AR103245A1 (es) * | 2014-12-24 | 2017-04-26 | Intervet Int Bv | Vacuna vectorial basada en hvt (herpes virus de los pavos) frente a nd (enfermedad de newcastle) - ibd (enfermedad de gumboro) mejorada |
US10537628B2 (en) | 2015-08-10 | 2020-01-21 | The Texas A&M University System | Recombinant turkey herpesvirus vaccines and uses thereof |
JP7046014B2 (ja) | 2016-06-17 | 2022-04-01 | インターベット インターナショナル ベー. フェー. | 伝染性喉頭気管炎ウイルスおよび伝染性ファブリキウス嚢病ウイルスの抗原をコードする組換え非病原性マレック病ウイルスコンストラクト |
JOP20190088A1 (ar) * | 2016-10-21 | 2019-04-21 | Us Agriculture | نواقل مؤتلفة للتعبير عن مولدات مضاد فيروس انفلونزا الطيور و استخداماتها |
WO2018112051A1 (en) * | 2016-12-14 | 2018-06-21 | Merial, Inc. | Recombinant hvt vectors expressing multiple antigens of avian pathogens, and vaccines comprising them |
CN106929483B (zh) * | 2017-01-19 | 2020-09-25 | 北京邦卓生物科技有限公司 | 表达鸡新城疫病毒f基因的重组火鸡疱疹病毒的构建及其应用 |
CN106701693A (zh) * | 2017-01-19 | 2017-05-24 | 北京邦卓生物科技有限公司 | 表达血清ⅰ型马立克氏病病毒gb基因的重组火鸡疱疹病毒的构建及其应用 |
EP3391903B1 (en) * | 2017-04-21 | 2022-02-23 | The Pirbright Institute | Recombinant gallid herpesvirus 3 vaccines encoding heterologous avian pathogen antigens |
CN107099513B (zh) * | 2017-06-22 | 2020-07-14 | 北京邦卓生物科技有限公司 | 一种共表达ndv hn和ibdv vp2基因的hvt的构建及其应用 |
CN107254450A (zh) * | 2017-07-20 | 2017-10-17 | 扬州大学 | 克服鸡新城疫母源抗体影响的嵌合新城疫病毒疫苗载体候选株及构建方法 |
CN107603958A (zh) * | 2017-09-29 | 2018-01-19 | 天津农学院 | 融合表达TM‑1基因和gD基因重组腺病毒的构建方法及重组腺病毒和应用 |
EP3694987A1 (en) * | 2017-10-12 | 2020-08-19 | Intervet International B.V. | Recombinant non-pathogenic marek's disease virus constructs encoding multiple heterologous antigens |
CN111542337A (zh) | 2017-12-20 | 2020-08-14 | 英特维特国际股份有限公司 | 用于细胞相关联的α疱疹病毒疫苗的改良稀释剂 |
CN108543067A (zh) * | 2017-12-25 | 2018-09-18 | 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) | 共表达h5亚型禽流感ha蛋白和传染性法氏囊vp2蛋白的重组火鸡疱疹病毒疫苗株 |
EP3743084A4 (en) * | 2018-01-24 | 2021-12-08 | Virogin Biotech Canada Ltd | RECOMBINANT ANTIVIRAL VACCINES |
CN109468315B (zh) * | 2018-12-07 | 2021-09-07 | 袁隆平农业高科技股份有限公司 | 水稻耐淹基因Sub1共显性分子标记及应用 |
MX2021007408A (es) * | 2018-12-21 | 2021-07-15 | Ceva Sante Animale | Virus del herpes aviar recombinantes que contienen multiples genes extra?os. |
CN114616325A (zh) | 2019-09-11 | 2022-06-10 | 硕腾服务有限责任公司 | 表达禽病原体抗原的重组火鸡疱疹病毒载体和其用途 |
CN110872578B (zh) * | 2019-11-29 | 2022-09-16 | 扬州优邦生物药品有限公司 | 一株变异株传染性法氏囊病毒、亚单位疫苗及其制备方法和应用 |
US11299517B2 (en) * | 2020-04-15 | 2022-04-12 | The United States Of America, As Represented By The Secretary Of Agriculture | Recombinant vaccine against Marek's disease and Newcastle disease |
MX2022016337A (es) | 2020-06-17 | 2023-04-10 | Boehringer Ingelheim Vetmedica Gmbh | Vectores de hvt recombinantes que expresan hemaglutinina de influenza y composiciones inmunogenicas, su produccion y usos. |
CN112206317B (zh) * | 2020-10-12 | 2023-09-22 | 浙江省淡水水产研究所 | 一种草鱼出血病二价核酸菌蜕疫苗的制备方法 |
JP2023545524A (ja) | 2020-10-15 | 2023-10-30 | セヴァ サンテ アニマレ | 組換えhvt及びその使用 |
CN114317827B (zh) * | 2022-01-07 | 2023-03-24 | 河南省农业科学院 | 一种鉴别不同血清型马立克病病毒感染与免疫的多重pcr引物、方法及应用 |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5174993A (en) | 1981-12-24 | 1992-12-29 | Health Research Inc. | Recombinant avipox virus and immunological use thereof |
US4603112A (en) | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
US4769330A (en) | 1981-12-24 | 1988-09-06 | Health Research, Incorporated | Modified vaccinia virus and methods for making and using the same |
US4708871A (en) | 1983-03-08 | 1987-11-24 | Commonwealth Serum Laboratories Commission | Antigenically active amino acid sequences |
WO1987004463A1 (en) | 1986-01-27 | 1987-07-30 | Syntro Corporation | Attenuated herpesviruses, herpesviruses which include foreign dna encoding an amino acid sequence and vaccine containing same |
JP2779447B2 (ja) | 1988-03-20 | 1998-07-23 | 財団法人阪大微生物病研究会 | 弱毒マレック病ウイルス・ベクターを用いる組換え遺伝子作成法、及び該ウイルスの組換え体 |
ES2070997T3 (es) | 1989-12-04 | 1995-06-16 | Akzo Nobel Nv | Virus de herpes recombinante de pavos y vacunas vector vivas derivadas de los mismos. |
DE69233158T2 (de) | 1991-03-07 | 2004-05-13 | Connaught Technology Corp., Greenville | Gentechnologisch hergestellter stamm für impfstoffe |
BE1004877A3 (fr) | 1991-05-27 | 1993-02-16 | Solvay | Virus de l'avipox recombinant, culture de cellules infectees par ce virus et vaccins pour la volaille derives de ce virus. |
US5853733A (en) | 1993-02-26 | 1998-12-29 | Syntro Corporation | Recombinant herpesvirus of turkeys and uses thereof |
US6183753B1 (en) | 1994-08-09 | 2001-02-06 | Schering-Plough Veterinary Corp. | Recombinant chimeric virus and uses thereof |
FR2719056B1 (fr) | 1994-04-20 | 1996-09-06 | Rhone Merieux | Herpesvirus transformés pour exprimer gD in vitro. |
CA2626498C (en) * | 1994-08-09 | 2011-04-12 | Schering-Plough Limited | Recombinant chimeric virus |
RU2059414C1 (ru) * | 1994-12-09 | 1996-05-10 | Государственная Курская биофабрика - Фирма "БИОК" | Поливалентная вакцина для профилактики болезни марека и способ ее изготовления |
FR2728795B1 (fr) * | 1994-12-30 | 1997-03-21 | Rhone Merieux | Vaccin vivant recombinant aviaire, utilisant comme vecteur un virus herpes aviaire |
JPH104956A (ja) * | 1996-06-21 | 1998-01-13 | Univ Michigan State | マレク病ワクチン製造のための維持可能な細胞株の改良 |
FR2751225B1 (fr) * | 1996-07-19 | 1998-11-27 | Rhone Merieux | Formule de vaccin polynucleotidique aviaire |
DE69733020T2 (de) | 1996-10-11 | 2006-02-16 | The Regents Of The University Of California, Oakland | Immunostimulierende oligonucleotidekonjugate |
US5980912A (en) | 1997-03-25 | 1999-11-09 | Zonagen, Inc. | Chitosan induced immunopotentiation |
EP1026246B1 (en) * | 1997-10-03 | 2006-11-29 | Zeon Corporation | Avian infectious herpesvirus recombinants and recombinant vaccines prepared with the use of the same |
EP0974660A1 (en) | 1998-06-19 | 2000-01-26 | Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) | Newcastle disease virus infectious clones, vaccines and diagnostic assays |
US6299882B1 (en) | 1999-04-09 | 2001-10-09 | Schering Corporation | UL54.5 of Marek's disease virus (MDV) |
KR100354972B1 (ko) * | 2000-04-11 | 2002-10-05 | 대한민국 | 닭전염성기관지염 바이러스 s1 단백질을 발현하는유전자재조합 마렉바이러스 및 그의 제조방법 |
US6764684B2 (en) * | 2001-09-28 | 2004-07-20 | Zeon Corporation | Avian herpesvirus-based recombinant infectious bursal disease vaccine |
US6866852B2 (en) | 2002-01-31 | 2005-03-15 | Zeon Corporation | Recombinant herpesvirus of turkeys and use thereof |
KR100801180B1 (ko) * | 2006-09-26 | 2008-02-05 | 주식회사 고려비엔피 | 약독화된 재조합 뉴캐슬병 바이러스 및 이를 함유하는뉴캐슬병 백신 |
CN105567648B (zh) * | 2009-04-15 | 2019-09-03 | 法国诗华大药厂 | 用于免疫接种水禽物种的重组禽疱疹病毒载体和疫苗 |
WO2013082327A1 (en) | 2011-11-30 | 2013-06-06 | Merial Limited | Recombinant hvt vectors expressing antigens of avian pathogens and uses thereof |
-
2012
- 2012-11-29 WO PCT/US2012/067135 patent/WO2013082327A1/en active Application Filing
- 2012-11-29 RU RU2014126375A patent/RU2620936C2/ru active
- 2012-11-29 ES ES12805843T patent/ES2719409T5/es active Active
- 2012-11-29 EP EP19167408.4A patent/EP3572092A1/en active Pending
- 2012-11-29 HU HUE17179863A patent/HUE047909T2/hu unknown
- 2012-11-29 LT LTEP12801680.5T patent/LT2785373T/lt unknown
- 2012-11-29 HR HRP20190525TT patent/HRP20190525T8/hr unknown
- 2012-11-29 SI SI201231721T patent/SI2785373T1/sl unknown
- 2012-11-29 PT PT12805843T patent/PT2785374T/pt unknown
- 2012-11-29 PL PL12805843.5T patent/PL2785374T5/pl unknown
- 2012-11-29 PE PE2014000764A patent/PE20141482A1/es active IP Right Grant
- 2012-11-29 AR ARP120104498A patent/AR090401A1/es active IP Right Grant
- 2012-11-29 RS RS20200111A patent/RS59892B1/sr unknown
- 2012-11-29 HU HUE12801680A patent/HUE047724T2/hu unknown
- 2012-11-29 KR KR1020147017914A patent/KR102013135B1/ko active IP Right Grant
- 2012-11-29 RS RS20190443A patent/RS58610B1/sr unknown
- 2012-11-29 EP EP19167407.6A patent/EP3578199A1/en active Pending
- 2012-11-29 PL PL17179863T patent/PL3251691T3/pl unknown
- 2012-11-29 CA CA2857025A patent/CA2857025C/en active Active
- 2012-11-29 UA UAA201407192A patent/UA118651C2/uk unknown
- 2012-11-29 PL PL12801680T patent/PL2785373T3/pl unknown
- 2012-11-29 ME MEP-2019-103A patent/ME03433B/me unknown
- 2012-11-29 DK DK12801680.5T patent/DK2785373T3/da active
- 2012-11-29 AR ARP120104499A patent/AR089039A1/es not_active Application Discontinuation
- 2012-11-29 DK DK17179863.0T patent/DK3251691T3/da active
- 2012-11-29 CN CN201280066324.4A patent/CN104159605B/zh active Active
- 2012-11-29 MX MX2014006361A patent/MX361893B/es active IP Right Grant
- 2012-11-29 SI SI201231722T patent/SI3251691T1/sl unknown
- 2012-11-29 BR BR112014013276-3A patent/BR112014013276B1/pt active IP Right Grant
- 2012-11-29 WO PCT/US2012/067123 patent/WO2013082317A2/en active Application Filing
- 2012-11-29 ES ES12801680T patent/ES2785045T3/es active Active
- 2012-11-29 HU HUE12805843A patent/HUE042471T2/hu unknown
- 2012-11-29 EP EP17179863.0A patent/EP3251691B1/en active Active
- 2012-11-29 DK DK12805843.5T patent/DK2785374T3/en active
- 2012-11-29 RS RS20200113A patent/RS59893B1/sr unknown
- 2012-11-29 SI SI201231570T patent/SI2785374T1/sl unknown
- 2012-11-29 EP EP22174415.4A patent/EP4112073A1/en active Pending
- 2012-11-29 PT PT128016805T patent/PT2785373T/pt unknown
- 2012-11-29 ES ES17179863T patent/ES2775218T3/es active Active
- 2012-11-29 IN IN4833CHN2014 patent/IN2014CN04833A/en unknown
- 2012-11-29 MX MX2014006360A patent/MX365984B/es active IP Right Grant
- 2012-11-29 JP JP2014544892A patent/JP6149301B2/ja active Active
- 2012-11-29 CN CN201610341171.XA patent/CN105920598A/zh active Pending
- 2012-11-29 EP EP17181500.4A patent/EP3263130A1/en not_active Ceased
- 2012-11-29 CN CN201280066323.XA patent/CN104159604B/zh active Active
- 2012-11-29 EP EP12805843.5A patent/EP2785374B2/en active Active
- 2012-11-29 PT PT171798630T patent/PT3251691T/pt unknown
- 2012-11-29 LT LTEP17179863.0T patent/LT3251691T/lt unknown
- 2012-11-29 EP EP12801680.5A patent/EP2785373B1/en active Active
- 2012-11-29 LT LTEP12805843.5T patent/LT2785374T/lt unknown
-
2014
- 2014-05-23 ZA ZA2014/03804A patent/ZA201403804B/en unknown
- 2014-05-26 PH PH12014501174A patent/PH12014501174A1/en unknown
- 2014-06-24 CO CO14136125A patent/CO7061033A2/es unknown
- 2014-10-21 HK HK18107348.4A patent/HK1247832A1/zh unknown
- 2014-10-21 HK HK18108356.1A patent/HK1248566A1/zh unknown
- 2014-10-21 HK HK14110483A patent/HK1197175A1/xx unknown
-
2015
- 2015-01-15 HK HK15100455.1A patent/HK1200018A1/xx unknown
- 2015-12-16 PH PH12015502790A patent/PH12015502790B1/en unknown
-
2019
- 2019-04-09 CY CY20191100394T patent/CY1121528T1/el unknown
- 2019-12-10 HR HRP20192215TT patent/HRP20192215T1/hr unknown
- 2019-12-12 HR HRP20192241TT patent/HRP20192241T1/hr unknown
- 2019-12-16 CY CY20191101319T patent/CY1122872T1/el unknown
-
2020
- 2020-01-07 CY CY20201100003T patent/CY1124618T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1122872T1 (el) | Ανασυνδυασμενοι hvt φορεις οι οποιοι εκφραζουν αντιγονα παθογονων των πτηνων και χρησεις αυτων | |
PH12019501366A1 (en) | Recombinant hvt vectors expressing multiple antigens of avian pathogens, and vaccines comprising them | |
CY1124867T1 (el) | Αντισωματα μονης περιοχης που κατευθυνονται εναντι ενδοκυτταρικων αντιγονων | |
CY1124202T1 (el) | Εμβολια ανασυνδυασμενου zika | |
PH12018501602A1 (en) | Subunit immersion vaccines for fish | |
MX2016012845A (es) | Vacuna contra el virus de la diarrea epidemica porcina. | |
MX2016016722A (es) | Coronavirus. | |
PH12019500854A1 (en) | Recombinant vectors expressing antigens of avian influenza virus and uses thereof | |
CY1124707T1 (el) | Συνθεσεις και μεθοδοι για την επαγωγη ενισχυμενης ανοσοαποκρισης με χρηση φορεων ιων poxvirus (ευλογοϊων) | |
PH12019500557A1 (en) | New ehv insertion site orf70 | |
MX2019007252A (es) | Metodos y composiciones para vacunas del virus del dengue. | |
PH12017501100B1 (en) | Recombinant swinepox virus and vaccines | |
MX338052B (es) | Vectores de parapoxvirus que contienen el antigeno del virus de la rabia. | |
DK3471766T3 (da) | Rekombinante, ikke-patogene mareks sygdomsviruskonstrukter, der koder for infektiøs laryngotracheitisvirus- og infektiøs bursitis virus-antigener patentkrav | |
EA201990719A1 (ru) | Новые промоторы | |
MX2019007924A (es) | Vacunas contra la influenza. |