CY1122156T1 - Αντισωματα κατα του σχετιζομενου με τον νεφρο αντιγονου 1 και αντιγονοδεσμευτικα θραυσματα αυτων - Google Patents

Αντισωματα κατα του σχετιζομενου με τον νεφρο αντιγονου 1 και αντιγονοδεσμευτικα θραυσματα αυτων

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Publication number
CY1122156T1
CY1122156T1 CY20191100961T CY191100961T CY1122156T1 CY 1122156 T1 CY1122156 T1 CY 1122156T1 CY 20191100961 T CY20191100961 T CY 20191100961T CY 191100961 T CY191100961 T CY 191100961T CY 1122156 T1 CY1122156 T1 CY 1122156T1
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CY
Cyprus
Prior art keywords
cancer
antigen
antibodies
binding fragments
kidney
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Application number
CY20191100961T
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English (en)
Inventor
Gilles Bernard Tremblay
Anna N. MORAITIS
Traian Sulea
Mario Filion
Original Assignee
Adc Therapeutics Sa
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Filing date
Publication date
Application filed by Adc Therapeutics Sa filed Critical Adc Therapeutics Sa
Publication of CY1122156T1 publication Critical patent/CY1122156T1/el

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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Abstract

Νέα αντισώματα και αντιγονοδεσμευτικά θραύσματα που δεσμεύονται ειδικά στο KAAG1 και που μπορεί να χρησιμοποιηθούν στην αγωγή, την ανίχνευση και τη διάγνωση του καρκίνου που περιλαμβάνει κύτταρα που εκφράζουν KAAG1 αποκαλύπτονται στο παρόν. Τα κύτταρα που εκφράζουν τα αντισώματα και τα αντιγονοδεσμευτικά θραύσματα καθώς επίσης και μέθοδοι ανιχνεύσεως και αγωγής του καρκίνου δια της χρήσεως των αντισωμάτων και θραυσμάτων αποκαλύπτονται επίσης. Οι ενδείξεις του καρκίνου που μπορεί να ωφεληθούν από αυτήν την αγωγή ή την ανίχνευση περιλαμβάνουν καρκίνο των ωοθηκών, νεφρικό καρκίνο, καρκίνο του πνεύμονα, ορθοκολικό καρκίνο, καρκίνο του μαστού, καρκίνο του εγκεφάλου και καρκίνο του προστάτη καθώς επίσης και μελανώματα.
CY20191100961T 2011-03-31 2019-09-16 Αντισωματα κατα του σχετιζομενου με τον νεφρο αντιγονου 1 και αντιγονοδεσμευτικα θραυσματα αυτων CY1122156T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161470063P 2011-03-31 2011-03-31
US201161533346P 2011-09-12 2011-09-12
PCT/CA2012/000296 WO2012129668A1 (en) 2011-03-31 2012-03-28 Antibodies against kidney associated antigen 1 and antigen binding fragments thereof
EP12765926.6A EP2691421B1 (en) 2011-03-31 2012-03-28 Antibodies against kidney associated antigen 1 and antigen binding fragments thereof

Publications (1)

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CY1122156T1 true CY1122156T1 (el) 2020-11-25

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AU (1) AU2012234754B2 (el)
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CA2829105C (en) * 2011-03-31 2019-09-24 Alethia Biotherapeutics Inc. Antibodies against kidney associated antigen 1 and antigen binding fragments thereof
PL2802351T3 (pl) 2012-01-09 2019-11-29 Adc Therapeutics Sa Środki do leczenia potrójnie negatywnego raka piersi
US20130280282A1 (en) * 2012-04-24 2013-10-24 Daiichi Sankyo Co., Ltd. Dr5 ligand drug conjugates
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