CY1121852T1 - Μορφοποιησεις και μεθοδοι παρασκευης μορφοποιησεων για χρηση στον καθαρισμο του παχεος εντερου - Google Patents

Μορφοποιησεις και μεθοδοι παρασκευης μορφοποιησεων για χρηση στον καθαρισμο του παχεος εντερου

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Publication number
CY1121852T1
CY1121852T1 CY20191100344T CY191100344T CY1121852T1 CY 1121852 T1 CY1121852 T1 CY 1121852T1 CY 20191100344 T CY20191100344 T CY 20191100344T CY 191100344 T CY191100344 T CY 191100344T CY 1121852 T1 CY1121852 T1 CY 1121852T1
Authority
CY
Cyprus
Prior art keywords
formulations
methods
colon cleansing
fraction
preparing
Prior art date
Application number
CY20191100344T
Other languages
English (en)
Inventor
Reza Fathi
Patrick Laughlin MCLEAN
Original Assignee
Redhill Biopharma Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Redhill Biopharma Ltd. filed Critical Redhill Biopharma Ltd.
Publication of CY1121852T1 publication Critical patent/CY1121852T1/el

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08—Oxides; Hydroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Στο παρόν έγγραφο δημοσιεύονται μορφοποιήσεις και μέθοδοι παρασκευής μορφοποιήσεων για χρήση στον καθαρισμό του παχέος εντέρου. Σε μια υλοποίηση, μια στερεή δοσολογική μορφοποίηση περιλαμβάνει ένα ενδοκοκκικό κλάσμα, αναμεμιγμένο με ένα εξωκοκκικό κλάσμα, στην οποία το ενδοκοκκικό κλάσμα περιλαμβάνει κοκκία περιέχοντα τουλάχιστον έναν ωσμωτικό καθαρτικό παράγοντα, τουλάχιστον ένα αντιόξινο και ένα πρώτο, φαρμακευτικά αποδεκτό έκδοχο και στην οποία το εξωκοκκικό κλάσμα περιέχει τουλάχιστον ένα ή περισσότερα οργανικά οξέα, ένα μη μεταλλικό λιπαντικό στοιχείο και ένα δεύτερο, φαρμακευτικά αποδεκτό έκδοχο.
CY20191100344T 2012-07-27 2019-03-26 Μορφοποιησεις και μεθοδοι παρασκευης μορφοποιησεων για χρηση στον καθαρισμο του παχεος εντερου CY1121852T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261676608P 2012-07-27 2012-07-27
PCT/IB2013/001640 WO2014016671A2 (en) 2012-07-27 2013-07-26 Formulations and methods of manufacturing formulations for use in colonic evacuation

Publications (1)

Publication Number Publication Date
CY1121852T1 true CY1121852T1 (el) 2020-07-31

Family

ID=49997911

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20191100344T CY1121852T1 (el) 2012-07-27 2019-03-26 Μορφοποιησεις και μεθοδοι παρασκευης μορφοποιησεων για χρηση στον καθαρισμο του παχεος εντερου

Country Status (25)

Country Link
US (3) US10166219B2 (el)
EP (1) EP2877163B1 (el)
JP (1) JP6454640B2 (el)
KR (1) KR102152873B1 (el)
CN (2) CN104797244B (el)
AU (1) AU2013294737B2 (el)
BR (1) BR112015001640A2 (el)
CA (1) CA2880282C (el)
CY (1) CY1121852T1 (el)
DK (1) DK2877163T3 (el)
ES (1) ES2717282T3 (el)
HK (1) HK1212596A1 (el)
HR (1) HRP20190550T1 (el)
HU (1) HUE043852T2 (el)
IL (1) IL236791B (el)
IN (1) IN2015DN00637A (el)
MX (1) MX366707B (el)
NZ (1) NZ704014A (el)
PH (1) PH12015500165A1 (el)
PL (1) PL2877163T3 (el)
PT (1) PT2877163T (el)
RU (1) RU2015106688A (el)
SI (1) SI2877163T1 (el)
TR (1) TR201904884T4 (el)
WO (1) WO2014016671A2 (el)

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CA2821196C (en) 2010-12-13 2022-11-22 Thomas Julius Borody Gastric and colonic formulations and methods for making and using them
TR201904884T4 (tr) 2012-07-27 2019-05-21 Redhill Biopharma Ltd Koloni̇k boşaltmada kullanima yöneli̇k formülasyonlar ve formülasyonlarin üreti̇m yöntemleri̇
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KR101420315B1 (ko) 2014-03-19 2014-07-17 남봉길 약학적 액제 조성물
RU2018105869A (ru) 2015-08-17 2019-09-19 Ферринг Б.В. Жидкие составы, содержащие пикосульфат и цитрат магния
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