CY1119950T1 - Μη υδατικα μονοφασικα βιοσυμβατα ιξωδη οχηματα και μεθοδοι παρασκευης αυτων - Google Patents
Μη υδατικα μονοφασικα βιοσυμβατα ιξωδη οχηματα και μεθοδοι παρασκευης αυτωνInfo
- Publication number
- CY1119950T1 CY1119950T1 CY20121100281T CY121100281T CY1119950T1 CY 1119950 T1 CY1119950 T1 CY 1119950T1 CY 20121100281 T CY20121100281 T CY 20121100281T CY 121100281 T CY121100281 T CY 121100281T CY 1119950 T1 CY1119950 T1 CY 1119950T1
- Authority
- CY
- Cyprus
- Prior art keywords
- visual
- surfactant
- esters
- solvent
- copolymers
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Dispersion Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
Αποκαλύπτεται μη υδατικό μονοφασικό βιοσυμβατό ιξώδες όχημα ικανό να εναιωρήσει επωφελές μέσο και να διανείμει το επωφελές μέσο για παρατεταμένη χρονική περίοδο σε θερμοκρασία σώματος. Το όχημα περιλαμβάνει διαλύτη, επιφανειοδραστικό, και πολυμερές. Ο διαλύτης, το επιφανειοδραστικό και το πολυμερές δεν είναι τα ίδια. Ο διαλύτης είναι λαυρυλική αλκοόλη ή γαλακτικός λαυρυλεστέρας, το επιφανειοδραστικό επιλέγεται από την ομάδα που αποτελείται από εστέρες πολυυδρικών αλκοολών, αιθοξυλιωμένο καστορέλαιο, πολυσορβικά, εστέρες ή αιθέρες κορεσμένων αλκοολών, και συμπολυμερή κατά συστάδες πολυοξυαιθυλενίου-πολυοξυπροπυλενίου, και το πολυμερές επιλέγεται από την ομάδα που αποτελείται από πολυεστέρες, πυρρολιδόνες, εστέρες ή αιθέρες ακόρεστων αλκοολών, και συμπολυμερή κατά συστάδες πολυοξυαιθυλενίου-πολυοξυπροπυλενίου.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11917099P | 1999-02-08 | 1999-02-08 | |
EP00913350A EP1152749B1 (en) | 1999-02-08 | 2000-02-02 | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1119950T1 true CY1119950T1 (el) | 2018-12-12 |
Family
ID=22382917
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20121100281T CY1119950T1 (el) | 1999-02-08 | 2015-05-22 | Μη υδατικα μονοφασικα βιοσυμβατα ιξωδη οχηματα και μεθοδοι παρασκευης αυτων |
Country Status (22)
Country | Link |
---|---|
EP (2) | EP1152749B1 (el) |
JP (1) | JP4861551B2 (el) |
KR (2) | KR100858856B1 (el) |
CN (1) | CN1232244C (el) |
AR (1) | AR029613A1 (el) |
AT (2) | ATE322889T1 (el) |
AU (1) | AU775904B2 (el) |
CA (1) | CA2361424C (el) |
CO (1) | CO5140096A1 (el) |
CY (1) | CY1119950T1 (el) |
DE (1) | DE60027272T2 (el) |
DK (1) | DK1666026T4 (el) |
ES (2) | ES2379471T5 (el) |
HK (2) | HK1041451B (el) |
HU (1) | HUP0200202A3 (el) |
IL (1) | IL144755A0 (el) |
NO (1) | NO20013861L (el) |
NZ (1) | NZ513441A (el) |
PT (2) | PT1152749E (el) |
TW (2) | TWI292716B (el) |
WO (1) | WO2000045790A2 (el) |
ZA (1) | ZA200106443B (el) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4931282B2 (ja) * | 2000-10-02 | 2012-05-16 | 日本ケミカルリサーチ株式会社 | 生理活性ペプチド含有粉末 |
US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
US20040224903A1 (en) * | 2002-12-19 | 2004-11-11 | Stephen Berry | Stable, non-aqueous, single-phase gels and formulations thereof for delivery from an implantable device |
JP2006521897A (ja) | 2003-03-31 | 2006-09-28 | アルザ・コーポレーション | 内部圧力を放散する手段を備える浸透ポンプ |
DE602004015755D1 (de) * | 2003-03-31 | 2008-09-25 | Alza Corp | Nicht wässrige einphasige visköse vehikel und formulierungen die diese vehikel verwenden |
US20050118206A1 (en) * | 2003-11-14 | 2005-06-02 | Luk Andrew S. | Surfactant-based gel as an injectable, sustained drug delivery vehicle |
US7772182B2 (en) * | 2004-08-05 | 2010-08-10 | Alza Corporation | Stable suspension formulations of erythropoietin receptor agonists |
US20060141040A1 (en) * | 2004-12-23 | 2006-06-29 | Guohua Chen | Injectable non-aqueous suspension |
US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
US7655254B2 (en) | 2005-02-03 | 2010-02-02 | Intarcia Therapeutics, Inc. | Implantable device for continuous delivery of interferon |
US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
ES2351527T3 (es) | 2006-05-30 | 2011-02-07 | Intarcia Therapeutics, Inc | Modulador de flujo en dos piezas con conducto interno para un sistema osmótico de administración. |
EP2359808B1 (en) | 2006-08-09 | 2013-05-22 | Intarcia Therapeutics, Inc | Osmotic delivery systems and piston assemblies |
EP2157967B1 (en) | 2007-04-23 | 2013-01-16 | Intarcia Therapeutics, Inc | Suspension formulations of insulinotropic peptides and uses thereof |
DK2170283T3 (en) | 2007-06-22 | 2019-04-15 | Univ Texas | CREATION OF STABLE SUBMICRON Peptide OR PROTEIN PARTICLES BY THIN FILM FREEZING |
CA2726861C (en) | 2008-02-13 | 2014-05-27 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
US8779094B2 (en) | 2008-11-16 | 2014-07-15 | Board Of Regents, The University Of Texas System | Low viscosity highly concentrated suspensions |
EP3323423B1 (en) | 2009-09-28 | 2020-06-17 | Intarcia Therapeutics, Inc | Rapid establishment and/or termination of substantial steady-state drug delivery |
KR101656121B1 (ko) | 2010-03-17 | 2016-09-08 | 노바리크 게엠베하 | 안압 증가를 치료하기 위한 약학 조성물 |
EP2444063A1 (en) | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Liquid pharmaceutical compositions for the delivery of active ingredients |
EP2462921A1 (en) | 2010-11-11 | 2012-06-13 | Novaliq GmbH | Liquid pharmaceutical compositions for the treatment of a posterior eye disease |
US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
KR101773648B1 (ko) | 2011-05-25 | 2017-08-31 | 노바리크 게엠베하 | 조갑에 투여를 위한 제약학적 조성물 |
CN103596554A (zh) | 2011-05-25 | 2014-02-19 | 诺瓦利克有限责任公司 | 基于半氟化烷烃类的外用药物组合物 |
CN104023743B (zh) | 2011-10-25 | 2017-05-03 | 普罗西纳治疗有限公司 | 抗体制剂和方法 |
PL2806886T3 (pl) | 2012-01-23 | 2017-08-31 | Novaliq Gmbh | Stabilizowane kompozycje białkowe oparte na semifluorowanych alkanach |
EP3488847B1 (en) | 2012-09-12 | 2023-11-08 | Novaliq GmbH | Semifluorinated alkane compositions |
CN106511322B (zh) | 2012-09-12 | 2021-09-17 | 诺瓦利克有限责任公司 | 包含半氟化烷烃的混合物的组合物 |
MX370207B (es) | 2013-07-23 | 2019-12-05 | Novaliq Gmbh | Composiciones estabilizadas de anticuerpos. |
US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
MA44390A (fr) | 2015-06-03 | 2019-01-23 | Intarcia Therapeutics Inc | Systèmes de mise en place et de retrait d'implant |
JP6642935B2 (ja) | 2015-09-30 | 2020-02-12 | ノバリック ゲーエムベーハー | 眼投与用の半フッ素化化合物 |
PL3355990T3 (pl) | 2015-09-30 | 2019-11-29 | Novaliq Gmbh | Semifluorowane związki oraz ich kompozycje |
SG11201810102SA (en) | 2016-05-16 | 2018-12-28 | Intarcia Therapeutics Inc | Glucagon-receptor selective polypeptides and methods of use thereof |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
JP2019520357A (ja) | 2016-06-23 | 2019-07-18 | ノバリック ゲーエムベーハー | 局所投与方法 |
AU2017329772B2 (en) | 2016-09-22 | 2023-02-02 | Novaliq Gmbh | Pharmaceutical compositions for use in the therapy of blepharitis |
ES2965677T3 (es) | 2016-09-23 | 2024-04-16 | Novaliq Gmbh | Composiciones oftálmicas que comprenden ciclosporina |
CN110225762A (zh) | 2017-01-03 | 2019-09-10 | 因塔西亚制药公司 | 包括glp-1受体激动剂的连续施用和药物的共同施用的方法 |
WO2018193093A1 (en) | 2017-04-21 | 2018-10-25 | Novaliq Gmbh | Iodine compositions |
WO2018206656A1 (en) | 2017-05-12 | 2018-11-15 | Novaliq Gmbh | Pharmaceutical compositions comprosing semifluorinated alkanes for the treatment of contact lense-related conditions |
KR20200059272A (ko) | 2017-09-27 | 2020-05-28 | 노바리크 게엠베하 | 안구 질환의 치료에서의 사용을 위한 라타노프로스트를 포함하는 안과적 조성물 |
WO2019068763A1 (en) | 2017-10-04 | 2019-04-11 | Novaliq Gmbh | OPHTHALMIC COMPOSITIONS COMPRISING F6H8 |
CA3091308A1 (en) | 2018-03-02 | 2019-09-06 | Novaliq Gmbh | Pharmaceutical compositions comprising nebivolol |
PL3856128T3 (pl) | 2018-09-27 | 2023-10-16 | Dermaliq Therapeutics, Inc. | Formulacja filtra przeciwsłonecznego do stosowania miejscowego |
CA3112031A1 (en) | 2018-10-12 | 2020-04-16 | Novaliq Gmbh | Ophthalmic composition for treatment of dry eye disease |
KR20220140711A (ko) | 2020-01-13 | 2022-10-18 | 듀렉트 코퍼레이션 | 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법 |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2528516A1 (de) † | 1974-07-05 | 1976-01-22 | Sandoz Ag | Neue galenische zubereitung |
JPS5788115A (en) * | 1980-10-06 | 1982-06-01 | Miles Lab | Stable non-aqueous solution of tetracycline antibiotic salt |
DE3320583A1 (de) † | 1983-06-08 | 1984-12-13 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue galenische zubereitungsformen von oralen antidiabetika und verfahren zu ihrer herstellung |
US5385738A (en) * | 1983-10-14 | 1995-01-31 | Sumitomo Pharmaceuticals Company, Ltd. | Sustained-release injection |
JPS61189230A (ja) * | 1985-02-19 | 1986-08-22 | Nippon Kayaku Co Ltd | エトポシド製剤 |
GB8528959D0 (en) * | 1985-11-25 | 1986-01-02 | Leo Pharm Prod Ltd | Chemical compounds |
DE3636123A1 (de) * | 1986-10-23 | 1988-05-05 | Rentschler Arzneimittel | Arzneizubereitungen zur oralen verabreichung, die als einzeldosis 10 bis 240 mg dihydropyridin enthalten |
JPH0720866B2 (ja) † | 1987-05-15 | 1995-03-08 | 三生製薬株式会社 | エペリゾン又はトルペリゾン或いはそれらの塩類含有経皮適用製剤 |
US5756450A (en) * | 1987-09-15 | 1998-05-26 | Novartis Corporation | Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms |
JP2794022B2 (ja) † | 1988-11-11 | 1998-09-03 | 三生製薬株式会社 | ブナゾシン或いはその塩類含有経皮適用製剤 |
US5112614A (en) * | 1989-09-14 | 1992-05-12 | Alza Corporation | Implantable delivery dispenser |
JPH03236317A (ja) † | 1989-12-06 | 1991-10-22 | Sansei Seiyaku Kk | ドパミン誘導体含有経皮用製剤 |
US5733572A (en) † | 1989-12-22 | 1998-03-31 | Imarx Pharmaceutical Corp. | Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles |
EP0520119A1 (de) † | 1991-06-17 | 1992-12-30 | Spirig Ag Pharmazeutische Präparate | Neue orale Diclofenaczubereitung |
WO1993009763A1 (en) † | 1991-11-15 | 1993-05-27 | Isp Investments Inc. | Pharmaceutical tablet with pvp having an enhanced drug dissolution rate |
US5314685A (en) † | 1992-05-11 | 1994-05-24 | Agouron Pharmaceuticals, Inc. | Anhydrous formulations for administering lipophilic agents |
AU6410494A (en) * | 1993-03-17 | 1994-10-11 | Alza Corporation | Device for the transdermal administration of alprazolam |
GB9309422D0 (en) * | 1993-05-07 | 1993-06-23 | Res Inst Medicine Chem | Chemical compounds |
DE69401945T3 (de) † | 1993-06-25 | 2004-09-02 | Alza Corp., Palo Alto | Einarbeitung eines poly-n-vinylamids in ein transdermales system |
CA2165802A1 (en) † | 1993-09-29 | 1995-04-06 | Eun Soo Lee | Monoglyceride/lactate ester permeation enhancer for oxybutynin |
EP0793963A4 (en) * | 1994-10-24 | 2001-12-12 | Nikken Chemicals Co Ltd | PREPARABLE TRANSDERMAL PREPARATION |
US5736159A (en) † | 1995-04-28 | 1998-04-07 | Andrx Pharmaceuticals, Inc. | Controlled release formulation for water insoluble drugs in which a passageway is formed in situ |
TR199701541T1 (xx) * | 1995-06-06 | 1998-03-21 | F.Hoffmann-La Roche Ag | Proteinaz engelleyici ve tekli gliserid i�eren farmas�tik bile�im. |
US6572879B1 (en) † | 1995-06-07 | 2003-06-03 | Alza Corporation | Formulations for transdermal delivery of pergolide |
US5904935A (en) * | 1995-06-07 | 1999-05-18 | Alza Corporation | Peptide/protein suspending formulations |
JP3534775B2 (ja) † | 1995-06-07 | 2004-06-07 | オーソ―マクニール ファーマシューティカル,インコーポレイテッド | 17−デアセチルノルゲスチマートを単独でまたはエストロゲンと組み合わせて投与するための経皮パッチおよび方法 |
US5906830A (en) † | 1995-09-08 | 1999-05-25 | Cygnus, Inc. | Supersaturated transdermal drug delivery systems, and methods for manufacturing the same |
US5766620A (en) † | 1995-10-23 | 1998-06-16 | Theratech, Inc. | Buccal delivery of glucagon-like insulinotropic peptides |
ATE277620T1 (de) † | 1996-07-15 | 2004-10-15 | Alza Corp | Neue formulierungen zur transdermale verabreichung von fluoxetinacetat und fluoxetinmaleat |
ES2191834T3 (es) † | 1996-10-24 | 2003-09-16 | Alza Corp | Agentes que facilitan la permeacion y destinados para composiciones, dispositivos y procedimientos de aporte transdermico de medicamentos. |
DE19646392A1 (de) † | 1996-11-11 | 1998-05-14 | Lohmann Therapie Syst Lts | Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht |
ATE318580T1 (de) * | 1996-12-20 | 2006-03-15 | Alza Corp | Gelzusammensetzungen und verfahren |
US20020039594A1 (en) † | 1997-05-13 | 2002-04-04 | Evan C. Unger | Solid porous matrices and methods of making and using the same |
SI9700186B (sl) † | 1997-07-14 | 2006-10-31 | Lek, Tovarna Farmacevtskih In Kemicnih Izdelkov, D.D. | Nova farmacevtska oblika z nadzorovanim sproscanjem zdravilnih ucinkovin |
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2000
- 2000-02-02 IL IL14475500A patent/IL144755A0/xx not_active IP Right Cessation
- 2000-02-02 PT PT00913350T patent/PT1152749E/pt unknown
- 2000-02-02 AT AT00913350T patent/ATE322889T1/de not_active IP Right Cessation
- 2000-02-02 AT AT06075430T patent/ATE537811T1/de active
- 2000-02-02 CA CA002361424A patent/CA2361424C/en not_active Expired - Fee Related
- 2000-02-02 DK DK06075430T patent/DK1666026T4/da active
- 2000-02-02 KR KR1020017010037A patent/KR100858856B1/ko active IP Right Grant
- 2000-02-02 KR KR1020087011434A patent/KR20080045300A/ko not_active Application Discontinuation
- 2000-02-02 HU HU0200202A patent/HUP0200202A3/hu unknown
- 2000-02-02 JP JP2000596910A patent/JP4861551B2/ja not_active Expired - Fee Related
- 2000-02-02 ES ES06075430.6T patent/ES2379471T5/es not_active Expired - Lifetime
- 2000-02-02 CN CNB008035636A patent/CN1232244C/zh not_active Expired - Fee Related
- 2000-02-02 EP EP00913350A patent/EP1152749B1/en not_active Expired - Lifetime
- 2000-02-02 ES ES00913350T patent/ES2261190T3/es not_active Expired - Lifetime
- 2000-02-02 NZ NZ513441A patent/NZ513441A/xx not_active IP Right Cessation
- 2000-02-02 AU AU34816/00A patent/AU775904B2/en not_active Ceased
- 2000-02-02 EP EP06075430.6A patent/EP1666026B2/en not_active Expired - Lifetime
- 2000-02-02 DE DE60027272T patent/DE60027272T2/de not_active Expired - Lifetime
- 2000-02-02 PT PT06075430T patent/PT1666026E/pt unknown
- 2000-02-02 WO PCT/US2000/002772 patent/WO2000045790A2/en active IP Right Grant
- 2000-02-03 TW TW089101904A patent/TWI292716B/zh active
- 2000-02-03 TW TW096109155A patent/TW200730199A/zh unknown
- 2000-02-07 AR ARP000100524A patent/AR029613A1/es not_active Application Discontinuation
- 2000-02-08 CO CO00007997A patent/CO5140096A1/es unknown
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2001
- 2001-08-06 ZA ZA200106443A patent/ZA200106443B/xx unknown
- 2001-08-08 NO NO20013861A patent/NO20013861L/no not_active Application Discontinuation
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2002
- 2002-04-30 HK HK02103234.8A patent/HK1041451B/zh not_active IP Right Cessation
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2006
- 2006-12-06 HK HK06113414.5A patent/HK1094528A1/xx not_active IP Right Cessation
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2015
- 2015-05-22 CY CY20121100281T patent/CY1119950T1/el unknown
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