CY1113735T1 - Εμβολια ογκου - Google Patents

Εμβολια ογκου

Info

Publication number
CY1113735T1
CY1113735T1 CY20121101024T CY121101024T CY1113735T1 CY 1113735 T1 CY1113735 T1 CY 1113735T1 CY 20121101024 T CY20121101024 T CY 20121101024T CY 121101024 T CY121101024 T CY 121101024T CY 1113735 T1 CY1113735 T1 CY 1113735T1
Authority
CY
Cyprus
Prior art keywords
monophosphoryl lipid
protein
vaccines
volume
volume vaccines
Prior art date
Application number
CY20121101024T
Other languages
English (en)
Inventor
Nathalie Garcon
Catherine Marie Ghislaine Gerard
Jean Stephenne
Original Assignee
Glaxosmithkline Biologicals S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0025573A external-priority patent/GB0025573D0/en
Priority claimed from GB0025574A external-priority patent/GB0025574D0/en
Priority claimed from US09/690,921 external-priority patent/US6544518B1/en
Application filed by Glaxosmithkline Biologicals S.A. filed Critical Glaxosmithkline Biologicals S.A.
Publication of CY1113735T1 publication Critical patent/CY1113735T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103—Receptors for growth factors
    • A61K39/001106—Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ErbB4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K39/001186—MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55583—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6068—Other bacterial proteins, e.g. OMP
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Permanent Magnet Type Synchronous Machine (AREA)
  • Control Of Throttle Valves Provided In The Intake System Or In The Exhaust System (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Η παρούσα εφεύρεση παρέχει νέες συνταγοποιήσεις ανοσοενισχυτικού για χρήση με αντιγόνα καρκίνου. Το ανοσοενισχυτικό περιλαμβάνει σαπωνίνη, ανοσοδιεγερτικό ολιγονουκλεοτίδιο και λιποπολυσακχαρίδιο που επιλέγεται από Μονοφωσφορύλο Λιπίδιο Α, 3-Ο-Αποακυλιωμένο Μονοφωσφορύλο Λιπίδιο Α και Διφωσφορύλο Λιπίδιο Α. Το αντιγόνο καρκίνου επιλέγεται από HASH-1 (ASCL-1) HASH-2 (ASCL-2) και πρωτεΐνη σύντηξης της MAGE και πρωτεΐνης D.
CY20121101024T 2000-10-18 2012-10-26 Εμβολια ογκου CY1113735T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0025573A GB0025573D0 (en) 2000-10-18 2000-10-18 Vaccine
GB0025574A GB0025574D0 (en) 2000-10-18 2000-10-18 Vaccine
US09/690,921 US6544518B1 (en) 1999-04-19 2000-10-18 Vaccines
EP10170408A EP2266603B1 (en) 2000-10-18 2001-10-16 Tumour vaccines

Publications (1)

Publication Number Publication Date
CY1113735T1 true CY1113735T1 (el) 2016-06-22

Family

ID=34082077

Family Applications (3)

Application Number Title Priority Date Filing Date
CY20081100112T CY1108526T1 (el) 2000-10-18 2008-01-31 Εμβολια εναντι καρκινων
CY20121100147T CY1112658T1 (el) 2000-10-18 2012-02-14 Εμβολια τα οποια περιεχουν αντιγονο μαgε συνδεομενο με θραυσμα πρωτεϊνης d
CY20121101024T CY1113735T1 (el) 2000-10-18 2012-10-26 Εμβολια ογκου

Family Applications Before (2)

Application Number Title Priority Date Filing Date
CY20081100112T CY1108526T1 (el) 2000-10-18 2008-01-31 Εμβολια εναντι καρκινων
CY20121100147T CY1112658T1 (el) 2000-10-18 2012-02-14 Εμβολια τα οποια περιεχουν αντιγονο μαgε συνδεομενο με θραυσμα πρωτεϊνης d

Country Status (14)

Country Link
US (1) US20050019340A1 (el)
EP (1) EP2266603B1 (el)
JP (1) JP2008285487A (el)
KR (1) KR100831139B1 (el)
AT (1) ATE534401T1 (el)
CY (3) CY1108526T1 (el)
DE (1) DE60131670T2 (el)
DK (2) DK1889630T3 (el)
ES (2) ES2392943T3 (el)
HK (3) HK1057992A1 (el)
IL (1) IL155282A (el)
PL (1) PL211151B1 (el)
PT (3) PT1326638E (el)
SI (1) SI2266603T1 (el)

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US7807803B2 (en) * 2002-07-03 2010-10-05 Coley Pharmaceutical Group, Inc. Nucleic acid compositions for stimulating immune responses
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Also Published As

Publication number Publication date
CY1108526T1 (el) 2014-04-09
PT2266603E (pt) 2012-11-02
PL211151B1 (pl) 2012-04-30
ES2377077T3 (es) 2012-03-22
KR20030044015A (ko) 2003-06-02
PT1889630E (pt) 2012-02-29
CY1112658T1 (el) 2016-02-10
PT1326638E (pt) 2008-02-06
US20050019340A1 (en) 2005-01-27
SI2266603T1 (sl) 2012-12-31
EP2266603B1 (en) 2012-09-12
HK1057992A1 (en) 2004-04-30
IL155282A (en) 2010-11-30
DK2266603T3 (da) 2012-11-05
HK1117729A1 (en) 2009-01-23
EP2266603A1 (en) 2010-12-29
ES2392943T3 (es) 2012-12-17
HK1147673A1 (en) 2011-08-19
JP2008285487A (ja) 2008-11-27
DE60131670T2 (de) 2008-10-30
DE60131670D1 (de) 2008-01-10
ATE534401T1 (de) 2011-12-15
KR100831139B1 (ko) 2008-05-20
DK1889630T3 (da) 2012-03-05

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